A.G. De sa Vivas MSc (Aisen)

Guest Supporting Staff

About Me

I am Biomedical Engineer by training with a general interest in technology. The exciting combination of biology, physics, chemistry, electronics, microfluidics and mechanics that entails the fabrication of Organs on Chips was the driving force that led me to do a PhD.

My project consists on the fabrication of a Heart on Chip and related fluidic interfacing, having as an ultimate goal a drug assay platform. The raising morbidity and the increasing costs in drug discovery in cardiovascular diseases lead to explore new methods that close the bridge between animal models and culture well plates - with physiological and simplistic limitations, respectively -, while reducing animal testing and costs. Such platform will unravel some of the intricate interactions that take place in the human heart and its vasculature, providing valuable insights to the field.

The, sometimes, conflicting ways of thinking of biology and engineering creates an exciting interphase where previously unrelated fields come into a meeting point, creating innovative and unraveling approaches that can be used in medicine. At AST, our interdisciplinary team brings to focus all the different aspects that are involved in the creation of Organs on Chips.


Engineering & Materials Science
Cell Culture
Endothelial Cells
Flow Control
Stem Cells
Medicine & Life Sciences


Vivas, A. (2022). Microfluidic and microengineered systems for automated cardiac organ-on-a-chip tissue culture. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036554930
Paloschi, V., Sabater-Lleal, M. , Middelkamp, H. , Vivas, A., Johansson, S. , van der Meer, A., Tenje, M., & Maegdefessel, L. (2021). Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research, 117(14), 2742-2754. https://doi.org/10.1093/cvr/cvab088

Contact Details

Visiting Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex (building no. 20), room ZH126
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex  ZH126
P.O. Box 217
7500 AE Enschede
The Netherlands

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