prof.dr. G.C.M. Kusters (Ron)

Ron Kusters is a full professor at the University of Twente, Enschede and a specialist laboratory medicine, head of the laboratory for clinical chemistry and haematology at the Jeroen Bosch Hospital in Den Bosch.

He obtained his PhD in 1992 at the University of Utrecht and after a post-doc at the Vrije Universiteit Amsterdam, he started his internship in laboratory medicine at the Medisch Spectrum Twente in Enschede. As a board certified clinical biochemist, he joined the Jeroen Bosch Hospital, one of the larger teaching hospitals in the Netherlands in 1998. In 2000 he was appointed medical manager (head of laboratory). In 2005, he was recognized as supervisor to interns in laboratory medicine and up till 2021, he supervised 11 residents in laboratory medicine.

At the University of Twente he was appointed professor (part time) in 2011. His chair is at the department of health technology and services research, part of the Technical Medical Centre. His inaugural lecture (Dutch) may be found at https://goo.gl/mQLubr.

His research (https://goo.gl/BasxuM) focuses on clinical and economical effectiveness of laboratory diagnostics with particular interest in innovative biochemical markers and innovative diagnostic technologies, like point of care testing

Medicine & Life Sciences

# Biomarkers
# General Practice
# General Practitioners
# Point-Of-Care Systems
# Point-Of-Care Testing
# Primary Health Care
# Procalcitonin
# Troponin

Faculty of Behavioural, Management and Social Sciences (BMS), Health Technology & Services Research (HTSR)

Direct Diagnostics/Sanquin
advisory
METC Brabant
member of METC Brabant
Jeroen Bosch Ziekenhuis
Klinisch Chemicus en medisch manager

Kurstjens, S., Schipper, A., Krabbe, J. , & Kusters, R. (2024). Predicting hemoglobinopathies using ChatGPT. Clinical Chemistry and Laboratory Medicine, 62(3), e59-e61. https://doi.org/10.1515/cclm-2023-0885

Heerink, J. S., Oudega, R., Gemen, E., Hopstaken, R. , Koffijberg, H. , & Kusters, R. (2023). Are the latest point-of-care D-dimer devices ready for use in general practice? A prospective clinical evaluation of five test systems with a capillary blood feature for suspected venous thromboembolism. Thrombosis Research, 232, 113-122. https://doi.org/10.1016/j.thromres.2023.10.014

Heerink, J. S., Oudega, R., Hopstaken, R. , Koffijberg, H. , & Kusters, R. (2023). Clinical decision rules in primary care: necessary investments for sustainable healthcare. Primary health care research & development, 24, Article e34. https://doi.org/10.1017/S146342362300021X

Heerink, J. S., Nies, J. , Koffijberg, H., Oudega, R. , Kip, M. M. A. , & Kusters, R. (2023). Two point-of-care test-based approaches for the exclusion of deep vein thrombosis in general practice: a cost-effectiveness analysis. BMC Primary Care, 24(1), Article 42. https://doi.org/10.1186/s12875-023-01992-z

Loots, FJ., Smits, M., Hopstaken, R. M., Jenniskens, K., Schroeten, F. H., Bruel, A. V. D., van de Pol, A. C., Oosterheert, J. J., Bouma, H., Little, P., Moore, M., van Delft, S., Rijpsma, D., Holkenborg, J., van Bussel, B. C. T., Laven, R., Bergmans, D. C. J. J., Hoogerwerf, J. J., Latten, G. H. P., ... Verheij, T. J. M. (2022). New clinical prediction model for early recognition of sepsis in adult primary care patients: a prospective diagnostic cohort study of development and external validation. British journal of general practice, 72(719), E437-E445. https://doi.org/10.3399/BJGP.2021.0520

Lingervelder, D. , Kip, M. M. A., Wiese, E. D. , Koffijberg, H. , Ijzerman, M. J. , & Kusters, R. (2022). The societal impact of implementing an at-home blood sampling device for chronic care patients: patient preferences and cost impact. BMC health services research, 22(1), Article 1529. https://doi.org/10.1186/s12913-022-08782-w

Kurstjens, S., De Bel, T., van der Horst, A. , Kusters, R., Krabbe, J., & van Balveren, J. (2022). Automated prediction of low ferritin concentrations using a machine learning algorithm. Clinical Chemistry and Laboratory Medicine, 60(12), 1921-1928. https://doi.org/10.1515/cclm-2021-1194

Loots, F. J., Smits, M., Jenniskens, K., van Zanten, A. R. H. , Kusters, R., Verheij, T. J. M., & Hopstaken, R. M. (2022). Added Diagnostic Value of Biomarkers in Patients with Suspected Sepsis: A Prospective Cohort Study in Out-Of-Hours Primary Care. The journal of applied laboratory medicine, 7(5), 1088-1097. https://doi.org/10.1093/jalm/jfac031

van Balveren, J. A., Verboeket-van de Venne, W. P. H. G. , Doggen, C. J. M., Erdem-Eraslan, L. , de Graaf, A. J., Krabbe, J. G., Musson, R. E. A., Oosterhuis, W. P., De Rijke, Y. B., van der Sijs, H., Tintu, A. N., Verheul, R. J., Hoedemakers, R. M. J. , & Kusters, R. (2022). Added value of drug-laboratory test interaction alerts in test result authorisation. Clinical Chemistry and Laboratory Medicine, 60(5), E108-E111. https://doi.org/10.1515/cclm-2022-0077

van Balveren, J. A., Erdem-Eraslan, L., Verboeket-van de Venne, W. P. H. G. , Doggen, C. J. M., Hofland, J., Oosterhuis, W. P., de Rijke, Y. B., Hoedemakers, R. M. J. , & Kusters, R. (2022). Awareness of drug laboratory test interactions is important for prevention of unnecessary additional diagnostics: An example. Clinica Chimica Acta, 530, 99-103. https://doi.org/10.1016/j.cca.2022.03.013

Covid Retro Collaboration, & CAPACITY-COVID consortium (2022). Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis. BMJ, 378, Article e069881. https://doi.org/10.1136/bmj-2021-069881

Heerink, J. S., Péquériaux, N., Oudega, R., de Jong, M. , Koffijberg, H. , & Kusters, R. (2022). Implementation of a care pathway for deep vein thrombosis: What's the benefit? Thrombosis Update, 7, Article 100109. https://doi.org/10.1016/j.tru.2022.100109

Lingervelder, D. (2022). The adoption of point-of-care testing in primary care: Health economic evidence and organisational factors. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036553681

van Balveren, J. A. (2022). Drug laboratory test interactions in clinical practice: Improving laboratory test interpretation by creating awareness. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789464194883

Heerink, J. S., Gemen, E., Oudega, R., Geersing, G. J., Hopstaken, R. , & Kusters, R. (2022). Performance of C-Reactive Protein, Procalcitonin, TAT Complex, and Factor VIII in Addition to D-Dimer in the Exclusion of Venous Thromboembolism in Primary Care Patients. The journal of applied laboratory medicine, 7(2), 444-455. https://doi.org/10.1093/jalm/jfab094

Lingervelder, D. , Koffijberg, H., Emery, J. D., Fennessy, P., Price, C. P., van Marwijk, H., Eide, T. B., Sandberg, S., Cals, J. W. L., Derksen, J. T. M. , Kusters, R. , & IJzerman, M. J. (2022). How to Realize the Benefits of Point-of-Care Testing at the General Practice: A Comparison of Four High-Income Countries. International Journal of Health Policy and Management, 11(10), 2248-2260. https://doi.org/10.34172/ijhpm.2021.143

van Balveren, J. A., Verboeket-van de Venne, W. P. H. G. , Doggen, C. J. M., Erdem-Eraslan, L. , De Graaf, A. J., Krabbe, J. G., Musson, R. E. A., Oosterhuis, W. P., De Rijke, Y. B., Van Der Sijs, H., Tintu, A. N., Verheul, R. J., Hoedemakers, R. M. J. , & Kusters, R. (2021). Real-time monitoring of drug laboratory test interactions: A proof of concept. Clinical Chemistry and Laboratory Medicine, 60(2), 235-242. https://doi.org/10.1515/cclm-2021-0790

Kurstjens, S., Gemen, E., Walk, S., Njo, T., Krabbe, J., Gijzen, K., Elisen, M. G. L. M. , & Kusters, R. (2021). Performance of commercially-available cholesterol self-tests. Annals of Clinical Biochemistry, 58(4), 289-296. https://doi.org/10.1177/0004563221992393

on behalf of the Dutch Society for Clinical Chemistry and Laboratory Medicine and task group ‘SMILE’: Signaling Medication Interactions and Laboratory test Expert system (2021). Clinical usefulness of drug-laboratory test interaction alerts: A multicentre survey. Clinical Chemistry and Laboratory Medicine, 59(7), 1239-1245. https://doi.org/10.1515/cclm-2020-1770

Lingervelder, D. , Koffijberg, H. , Kusters, R. , & IJzerman, M. J. (2021). Health Economic Evidence of Point-of-Care Testing: A Systematic Review. PharmacoEconomics - Open, 5(2), 157-173. https://doi.org/10.1007/s41669-020-00248-1

Kurstjens, S., Van Der Horst, A., Herpers, R., Geerits, M. W. L., Kluiters-De Hingh, Y. C. M., Göttgens, E. L., Blaauw, M. J. T., Thelen, M. H. M., Elisen, M. G. L. M. , & Kusters, R. (2020). Rapid identification of SARS-CoV-2-infected patients at the emergency department using routine testing. Clinical Chemistry and Laboratory Medicine, 58(9), 1587-1593. https://doi.org/10.1515/cclm-2020-0593

Kip, M. M. A., Oonk, M. L. J., Levin, M. D., Schop, A., Bindels, P. J. E. , Kusters, R. , & Koffijberg, H. (2020). Preventing overuse of laboratory diagnostics: a case study into diagnosing anaemia in Dutch general practice. BMC medical informatics and decision making, 20(1), Article 178. https://doi.org/10.1186/s12911-020-01198-8

Heerink, J., Gemen, E., Oudega, R., Hopstaken, R., Geersing, G. J. , & Kusters, R. (2020). Analytical performance and user-friendliness of five novel point-of-care D-dimer assays. Scandinavian Journal of Clinical and Laboratory Investigation, 80(5), 433-440. https://doi.org/10.1080/00365513.2020.1768586

van Balveren, J., Verboeket-Van de Venne, W., Erdem-Eraslan, L., de Graaf, A., Musson, R., Oosterhuis, W., van der Sijs, I., Verheul, R. , Kusters, R., & Hoedemakers, R. (2019). Real-time monitoring of drug-laboratory test interactions with an automated decision support application. Clinica Chimica Acta, 493(Suppl. 1), S531-S532. https://doi.org/10.1016/j.cca.2019.03.1118

Kip, M., Oonk, M. L. J., Levin, M. D. L. , Kusters, G. C. M. , & Koffijberg, E. (2019). More information worse decisions? Evaluating potential overuse of laboratory diagnostics in diagnosing anaemia. Value in health, 22(Suppl. 3), S908-S908. https://doi.org/10.1016/j.jval.2019.09.2665

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