dr. G.M.J. Segers - Nolten (Ine)

About Me

In 1974 Ine started her HBO education ‘Hoger Natuur Wetenschappelijk Onderwijs (HNWO)’ at the Analistenschool in Groningen. She graduated in 1978 and started working as a biochemical research assistant at the Afdeling Nucleaire Geneeskunde, Academisch Ziekenhuis Groningen on a project concerning hormone dependence of breast tumor development. In 1981 she moved to the University of Twente, Technische Hogeschool Twente at that time, where she was appointed as one of the first members of the starting Biophysical Engineering group headed by Professor Jan Greve.  Here she was responsible for setting up a biochemical/cell biological laboratory. She continued working as a research assistant within this group, and participated in many different projects. From 1998 till 2003 she worked as a PhD student within the BPE group on a project using single molecule fluorescence to study the human nucleotide excision DNA repair system. After obtaining her doctoral degree she stayed as a research scientist in the BPE group, later the Nanobiophysics group. Currently she is working within the NBP alpha-synuclein/ Parkinson’s disease related theme and she is managing the MESA+ BioNanoLab at the University of Twente, as the head of the facility.


Medicine & Life Sciences
Amyloid Beta-Protein (40-42)
Thioflavin T
Amyloid Fibril
Engineering & Materials Science


Vaneyck, J., Yousif, T. A. , Segers-Nolten, I. , Blum, C. , & Claessens, M. M. A. E. (2023). Quantitative Seed Amplification Assay: A Proof-of-Principle Study. The Journal of physical chemistry B, 127(8), 1735-1743. Advance online publication. https://doi.org/10.1021/acs.jpcb.2c08326
Other Contributions

Book contributions:

M.R. Loken, C.I. Civin, V.O. Shah, M.J. Fackler, G.M.J. Segers-Nolten and L.W.M.M. Terstappen, (1992) Characterization of erythroid, lymphoid and monomyeloid lineages in normal human bone marrow. Flow Cytometry in Hematology, Eds. Laerum, O.D. and Bjerknes, R. Academic Press, Inc., 31-42

I. Segers-Nolten, M. van Raaij and V. Subramaniam, (2011) Biophysical Analysis of Amyloid Formation. Comprehensive Biomaterials, Eds.Ducheyne, P.,Healy, K., Hutmacher , D.W.,Grainger, D.W. and Kirkpatrick, C.J. Elsevier Ltd., Volume 2, 347-359





Contact Details

Visiting Address

University of Twente
Drienerlolaan 5
7522 NB Enschede
The Netherlands

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Mailing Address

University of Twente
P.O. Box 217
7500 AE Enschede
The Netherlands