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dr. G.M.J. Segers - Nolten (Ine)

Researcher

About Me

In 1974 Ine started her HBO education ‘Hoger Natuur Wetenschappelijk Onderwijs (HNWO)’ at the Analistenschool in Groningen. She graduated in 1978 and started working as a biochemical research assistant at the Afdeling Nucleaire Geneeskunde, Academisch Ziekenhuis Groningen on a project concerning hormone dependence of breast tumor development. In 1981 she moved to the University of Twente, Technische Hogeschool Twente at that time, where she was appointed as one of the first members of the starting Biophysical Engineering group headed by Professor Jan Greve.  Here she was responsible for setting up a biochemical/cell biological laboratory. She continued working as a research assistant within this group, and participated in many different projects. From 1998 till 2003 she worked as a PhD student within the BPE group on a project using single molecule fluorescence to study the human nucleotide excision DNA repair system. After obtaining her doctoral degree she stayed as a research scientist in the BPE group, later the Nanobiophysics group. Currently she is working within the NBP alpha-synuclein/ Parkinson’s disease related theme and she is managing the MESA+ BioNanoLab at the University of Twente, as the head of the facility.

Expertise

Alpha-Synuclein
Proteins
Dna
Amyloid
Molecules
Document
Granulocytes
Coloring Agents

Publications

Recent Articles
Sidhu, A., Segers-Nolten, G. M. J., & Subramaniam, V. (2015). Disease related point mutations and solution conditions determine fibrillization behavior of alpha-synuclein. -. Poster session presented at 59th Annual Biophysical Society Meeting, Baltimore, Maryland, USA, .
Sidhu, A., Segers-Nolten, G. M. J., & Subramaniam, V. (2014). Functionalizing amyloid fibrils to create hybrid metal-protein bionanostructures. -. Poster session presented at 5th Scandinavian Symposium on Amyloid Diseases and Amyloid Mechanisms, Umea Sweden, .
Segers-Nolten, G. M. J. (2013). Facilities at MESA+ BioNanoLab. -. Poster session presented at MESA+ dag, Enschede, .
Kovalska, V. B., Yu Losytskyy, M., Tolmachev, O. I., Slominskii, Y. L., Segers-Nolten, G. M. J., Subramaniam, V., & Yarmoluk, S. M. (2012). Tri- and pentamethine cyanine dyes for fluorescent detection of alpha-synuclein oligomeric aggregates. Journal of fluorescence, 22(6), 1441-1448. DOI: 10.1007/s10895-012-1081-x
Other Contributions

Book contributions:

M.R. Loken, C.I. Civin, V.O. Shah, M.J. Fackler, G.M.J. Segers-Nolten and L.W.M.M. Terstappen, (1992) Characterization of erythroid, lymphoid and monomyeloid lineages in normal human bone marrow. Flow Cytometry in Hematology, Eds. Laerum, O.D. and Bjerknes, R. Academic Press, Inc., 31-42

I. Segers-Nolten, M. van Raaij and V. Subramaniam, (2011) Biophysical Analysis of Amyloid Formation. Comprehensive Biomaterials, Eds.Ducheyne, P.,Healy, K., Hutmacher , D.W.,Grainger, D.W. and Kirkpatrick, C.J. Elsevier Ltd., Volume 2, 347-359

 

 

 

 

UT Research Information System

Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst (building no. 28), room 156
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst  156
P.O. Box 217
7500 AE Enschede
The Netherlands

Working days

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