My research focuses on personalized eHealth services for patients with chronic diseases and older adults. The main focus is to investigate how ambulant measured physiological data combined with behavioral change techniques, contextual information and motivational strategies can lead to personalized buddy systems that effectively enable people to manage their health themselves, whether or not supported by professional guidance.

Within the chair it is investigated how physiological data can be fed back to patients in order to improve their knowledge about the disease/health, but also how this physiological data can be used to coach the patient, either directly through technology or through professional support, to manage their disease/health. 

With regard to direct patient coaching through technology, it is investigated how information obtained in daily life can be used in personalized feedback strategies that motivate people to change , but also to maintain those changes for the longer term. For professional guidance, the research focuses on intelligent recommender systems in which holistic patient information is translated into treatment recommendations

An important aspect within the chair is that technology does not stand on its own, but is always considered within the possible context(s) of use. This means that a sociotechnical approach is used and that end-users and other stakeholders are always strongly involved

In addition to research into strategies, evaluation and implementation are important areas of research. Evaluation is always part of research, starting with a narrow focus on technical accuracy at low TRL levels to a multilevel and multi-stakeholder evaluation at higher TRL levels. Since standard clinical studies are often not suitable for complex eHealth interventions, there is a focus on developing new evaluation methodologies that provide sufficient evidence for the added value of the technology within the context of use.

Nourished by the 'second valley of death' that eHealth interventions suffer from, research is performed into successful implementation strategies. The focus is on strategies that support not only the patient to change, but also the professional, the organization or even partnerships.

Expertise

  • Medicine and Dentistry

    • Patient
    • Maturity Onset Diabetes of the Young
    • Hip Fracture
    • Therapeutic Procedure
  • Psychology

    • Physical Activity
    • Treatment
    • Behavior
    • Questionnaires

Organisations

Ancillary activities

  • Stichting Marga KlompeRaad van Toezicht
  • MSTBoard of directors of MST
  • STZvice voorzitter samenwerkende topklinische ziekenhuizen
  • WGV zorg en welzijnBestuurslid WGV zorg en welzijn

Publications

Jump to: 2026 | 2025

2026

The Personalized cAnceR TreatmeNt and caRe (PARTNR) project: Optimizing intervention recommendations for breast cancer-related fatigue (2026)[Contribution to conference › Poster] TechMed Research Day 2026. Wijlens, K. A. E., Bode, C., Siesling, S., Vollenbroek-Hutten, M. M. R. & Witteveen, A.Structuring telemonitoring in heart failure care in The Netherlands: Design and operational protocol of a nationwide initiative (2026)European Heart Journal - Digital Health, 7(2). Article ztaf130. Jansen, C., Otterspoor, L. C., van Pol, P. E. J., IJff, G. C., Sinkeler, S. J., van den Heuvel, M., Jansen, M. E. P., Scholten, M., van Zutphen, K., Verstappen, C. C. A. G., Hermanides, N., Joosen, I. A., Heinen, S., Valk, J. G., Vollenbroek-Hutten, M. M. R., Schuuring, M. J. & van Hout, G. P. J.https://doi.org/10.1093/ehjdh/ztaf130Predicting Geriatric Rehabilitation Stays of ≤4 Weeks After Hip Fracture Surgery: Machine Learning Approach Using Physical Activity and Patient Data (2026)JMIR Rehabilitation and Assistive Technologies, 13. Article e79331. Krakers, S. M., Wouda, F. J., van Dartel, D., Vollenbroek-Hutten, M. M. R. & Hegeman, J. H.https://doi.org/10.2196/79331Digital Interventions for Knee Osteoarthritis: A Review of Personalization Strategies (2026)[Working paper › Preprint]. JMIR Publications. Lankheet, S., ter Laak Bolk, C., Middelweerd, A., Verra, W., Schröder, F. & Vollenbroek-Hutten, M.https://doi.org/10.2196/preprints.92190Synthetic Data Guided Feature Selection for Robust Activity Recognition in Older Adults (2026)[Working paper › Preprint]. ArXiv.org. Que, S., van Dartel, D., Heeringa, I., Hegeman, H., Vollenbroek-Hutten, M. & Wang, Y.https://doi.org/10.48550/arXiv.2601.17053

2025

Tailored eHealth Strategies for Lifestyle Support in Type 2 Diabetes Care (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Hietbrink, E. A. G.https://doi.org/10.3990/1.9789036569866Accelerometry-based Energy Expenditure Estimation During Activities of Daily Living: A Comparison Among Different Accelerometer Compositions (2025)In 2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2025 - Proceedings (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). IEEE. Que, S., Poelarends, R., Veltink, P., Vollenbroek-Hutten, M. & Wang, Y.https://doi.org/10.1109/EMBC58623.2025.11253809Physical and mental health, age and level of frailty related to the self-management abilities of community living older adults: A cross-sectional study (2025)Quality in Ageing and Older Adults, 26(3-4), 140-151. van Het Bolscher-Niehuis, M., Jansen-Kosterink, S. & Vollenbroek-Hutten, M.https://doi.org/10.1108/QAOA-02-2024-0011Systematic review of dynamically tailored eHealth interventions targeting physical activity and healthy diet in chronic disease (2025)npj Digital Medicine, 8(1). Article 696. Hietbrink, E. A. G., Lansink, C., Laverman, G. D., Vollenbroek-Hutten, M. M. R., Middelweerd, A. & Tabak, M.https://doi.org/10.1038/s41746-025-02054-7Holistic assessment of cancer-related fatigue after breast cancer: Working towards monitoring and personalized treatment advice (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Wijlens, K. A. E.https://doi.org/10.3990/1.9789036567725Breast cancer-related fatigue risk and intervention recommendations: What can and cannot be personalised? (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Beenhakker, L.https://doi.org/10.3990/1.9789036568425Coming to optimal cancer-related fatigue intervention recommendations after breast cancer: the personalized cancer treatment and care (partnr) project (2025)Supportive care in cancer, 33. Article 583. Witteveen, A., Wijlens, K. A. E., Beenhakker, L., Siesling, S., Bode, C. & Vollenbroek-Hutten, M. M. R.https://link.springer.com/article/10.1007/s00520-025-09559-7Personalization in eHealth; urgent needed but how to come forward?: A Methodological framework based on literature and expert knowledge (2025)[Contribution to conference › Abstract] 14th Supporting Health by Technology Conference 2025. Lankheet, S., Straková, S., Middelweerd, A., Schröder, F. F., Tabak, M. & Vollenbroek-Hutten, M. M. R.A holistic profile for cancer-related fatigue for women with breast cancer–a qualitative study (2025)Psychology & health, 40(6), 1037-1061. Wijlens, K. A. E., Beenhakker, L., Witteveen, A., Siemerink, E. J. M., Jansen, L., Gernaat, C., Schellekens, M. P. J., Siesling, S., Vollenbroek-Hutten, M. M. R. & Bode, C.https://doi.org/10.1080/08870446.2023.2289457Working toward Personalized Intervention Advice: A Survey Study on Preference Heterogeneity in Patients with Breast Cancer–Related Fatigue (2025)MDM Policy and Practice, 10(1). Beenhakker, L., Wijlens, K. A. E., Bode, C., Vollenbroek-Hutten, M. M. R., Siesling, S., van Til, J. & Witteveen, A.https://doi.org/10.1177/23814683241309676

Research profiles

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