Signal To Noise Ratios
UT Research Information System
Tumor-derived extracellular vesicles (tdEVs) may contain information important for the management of cancer patients. Their presence in biofluids of cancer patients renders them a promising biomarker for the diagnosis of cancer, the monitoring of therapy and the profiling of the tumor leading to a therapy tailored to the individual. Within the framework of the Cancer-ID program, novel techniques for the detection, isolation and characterization of tdEVs are being developed. EVs of different origins have been prepared and are being characterized with Raman spectroscopy, fluorescence microscopy and electrical impedance spectroscopy. Functionalized microfluidics and microsieves approaches are being developed to isolate them specifically from heterogeneous patient samples.