Expertise
Medicine & Life Sciences
# Clustered Regularly Interspaced Short Palindromic Repeats
# Colorectal Neoplasms
# Dna Cleavage
# Gene Editing
# Genetic Models
# Karyotype
# Organoids
Agriculture & Biology
# Gene Editing
Publications
Recent
Bollen, Y. (2022).
Karyotype diversification in colorectal cancer. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente.
https://doi.org/10.3990/1.9789036553506
Bollen, Y., Hageman, J. H., van Leenen, P., Derks, L. L. M., Ponsioen, B., Buissant des Amorie, J. R., Verlaan-Klink, I., van den Bos, M.
, Terstappen, L. W. M. M., van Boxtel, R., & Snippert, H. J. G. (2022).
Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage.
PLoS Biology,
20(1), 1-16. [e3001527].
https://doi.org/10.1371/journal.pbio.3001527
Bollen, Y., Stelloo, E., van Leenen, P., van den Bos, M., Ponsioen, B., Lu, B., van Roosmalen, M. J., Bolhaqueiro, A. C. F., Kimberley, C., Mossner, M., Cross, W. C. H., Besselink, N. J. M., van der Roest, B., Boymans, S., Oost, K. C., de Vries, S. G., Rehmann, H., Cuppen, E., Lens, S. M. A., ... Snippert, H. J. G. (2021).
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns.
Nature genetics,
53(8), 1187-1195.
https://doi.org/10.1038/s41588-021-00891-2
Bollen, Y., Post, J., Koo, B-K., & Snippert, H. J. G. (2018).
How to create state-of-the-art genetic model systems: strategies for optimal CRISPR-mediated genome editing.
Nucleic acids research,
46(13), 6435-6454.
https://doi.org/10.1093/nar/gky571
Contact Details
Visiting Address
University of Twente
Drienerlolaan 5
7522 NB Enschede
The Netherlands
Mailing Address
University of Twente
P.O. Box 217
7500 AE Enschede
The Netherlands