I am an innovative biophysicist and biochemist passionate about understanding and engineering ion channels, membrane proteins, and cellular communication mechanisms. Over the years, my research has evolved from mechanistic studies of ion channels and biohybrid systems to liquid biopsy innovations, bioelectrical signaling, and disease biomarker discovery.
With a growing patent portfolio, multiple ERC & NWO grants, and leadership in high-impact research, I bridge fundamental biophysics with real-world applications in cancer biology, neuroscience, and drug target discovery. My work spans from synthetic biology strategies for biomolecule labeling to novel, functional detection and testing of druggable protein markers of diseased cells from their extracellular vesicles in liquid biopsiesβpaving the way for new diagnostic and therapeutic technologies.
Research Focus Areas:
π¬ Liquid Biopsy & Biomarkers/drug target identification β Early disease detection & monitoring through extracellular vesicles (protein-based)
𧬠Synthetic Biology Tools β Unbiased biomolecule labeling for tracking cellular communication
β‘ Electrophysiology & Bioelectric Signaling β Understanding tumor, immune, and neuronal communication
π Membrane Protein-Based Drug Screening β liquid biopsy-based functional assays
Expertise
Biochemistry, Genetics and Molecular Biology
- Conductance
- Membrane
- Membrane Protein
- Protein
- Tension
- Surface Property
- Mechanosensitive Ion Channel
Chemistry
- Molecule
Organisations
Ancillary activities
- KNAW- NINAdvisory
- UTCWI committee member
Research Focus Areas:
π¬ Liquid Biopsy & Biomarkers/drug target identification β Early disease detection & monitoring through extracellular vesicles (protein-based)
𧬠Synthetic Biology Tools β Unbiased biomolecule labeling for tracking cellular communication
β‘ Electrophysiology & Bioelectric Signaling β Understanding tumor, immune, and neuronal communication
π Membrane Protein-Based Drug Screening β liquid biopsy-based functional assays
Publications
2023
2021
Research profiles
Courses academic year 2025/2026
Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses academic year 2024/2025
Courses academic year 2023/2024
- 193640999 - Internship BME
- 193650999 - Masters Assignment
- 193740050 - Biochemistry
- 201400273 - Capita Selecta BME TNW-MCBP
- 201700040 - In vitro diagnostics
- 201700187 - Soft and Biological Techniques
- 202001414 - Physical Biology
- 202001528 - Master Thesis DD Parma
- 202300227 - Prep. MSc Assignment CSE/Parma 2.5 EC
- 202300228 - Prep. MSc Assignment CSE/Parma 5 EC
Address

University of Twente
Carré (building no. 15), room C4431
Hallenweg 23
7522 NH Enschede
Netherlands
University of Twente
Carré C4431
P.O. Box 217
7500 AE Enschede
Netherlands