dr. A. Lenferink (Anke)

Assistant Professor
BMS-TPS-HTSR
a.lenferink@utwente.nl
+31534896311
Business card

As an Epidemiologist and Assistant Professor I am working at the section of Health Technology and Services Research, University of Twente, Enschede, where I am involved in education on quality in healthcare and in supervision of Bachelor and Master students (mainly Health Sciences) during their thesis.Ā I also have an affiliation with the department of Pulmonary Diseases at Medisch Spectrum Twente, Enschede.

My research interest lies in the area of self-management interventions for patients with chronic diseases.Ā Therefore, I am involved in the development of tailored self-management interventions for patients with COPD and comorbidities, and hope to continue and expand my collaboration with different (international) disciplines and institutions to contribute to further improvement of these interventions.Ā 


Other activities

Combined with my PhD project, I was also trained as an Epidemiologist B at the Radboud University Nijmegen. Therefore, I have weekly reviewed articles on methodological issues and followed courses and conferences about epidemiology and methodology. In addition, I have reviewed multiple papers for several peer-reviewed journals.

  • Member editorial review board Chronic Respiratory Disease
  • Member of The Netherlands Epidemiological Society (VVE)
  • Member of the Netherlands and European Respiratory Society (NRS & ERS)

Expertise

  • Nursing and Health Professions

    • Obstructive Lung Disease
    • Self Care
    • Patient
    • Disease Exacerbation

  • Medicine and Dentistry

    • Chronic Obstructive Pulmonary Disease
    • Inpatient
    • Symptom

  • Psychology

    • Self-Management

Organisations

My research interest lies in the area of self-management interventions for patients with chronic diseases.Ā Self-management interventions and digital health technologies enhance care delivery substitution from secondary to primary care and facilitate home-based support. This is essential to manage the increased number of patients ā€“mainly elderly- with chronic diseases. It is a challenge to tailor chronic disease self-management interventions to patientsā€™ needs and preferences, and make them better accessible and applicable for individuals. Recently, in multidisciplinary research an e-health self-management portal for patients with COPD and comorbidities has been developed, based on paper versions of a self-management intervention (COPE-III study).

Currently, I am the clinical coordinator of a European H2020 project:Ā REal-time data monitoring forĀ Shared,Ā Adaptive,Ā Multi-domain andĀ Personalised prediction and decision making forĀ Long-termĀ Pulmonary careĀ Ecosystems (RE-SAMPLE). In this project the UT (HTSR, SCS, BSS) is collaborating with MST, RRD and hospitals in Italy and Estonia to predict exacerbations of COPD and comorbidities from real-world data monitoring and artificial intelligence, and to develop a virtual companionship program to facilitate pro-active disease management. This research would give the opportunity to contribute to further adaptation and implementation of patient-tailored chronic disease self-management interventions.Ā 

In 2017, I completed my PhD at the Department of Pulmonary Medicine, Medisch Spectrum Twente, the Netherlands and the Flinders University, Adelaide, Australia. My PhD project was concerning the effectiveness of a self-management intervention in patients with Chronic Obstructive Pulmonary Disease (COPD) and comorbidities: the COPE-III study. This study was performed in two hospitals in the Netherlands and three hospitals in Adelaide, Australia. I obtained a Cotutelle agreement between the University of Twente, Enschede, and the Flinders University, Adelaide, for cooperation between the Dutch and Australian research groups on the self-management of patients with COPD. In 2014 and 2016, I visited Adelaide for two four-month research periods as part of my Cotutelle agreement.

Publications

Jump to: 2024 | 2023 | 2022

2024

Does adherence to exacerbation action plans matter? Insights from two COPD self-management studies (2024)Heliyon, 10(20). Article e39070. Schrijver, J., Effing, T., van Helden, J., van der Palen, J., van der Valk, P., Brusse-Keizer, M. & Lenferink, A.https://doi.org/10.1016/j.heliyon.2024.e39070Experiences of nurses working in novel virtual care centres in the Netherlands: a qualitative study (2024)BMC digital health, 2(70). Article 70. Leenen, J., Jordens, Y., Wegman, A., Heesink, L. & Lenferink, A.https://doi.org/10.1186/s44247-024-00127-3Potential for personalised and biomarker-guided COPD self-treatment approaches (2024)The Lancet Respiratory Medicine, 12(8), e48-e49. Lenferink, A., Citgez, E., van der Valk, P. D. L. P. M., van der Palen, J., Effing, T. & Brusse-Keizer, M. G. J.https://doi.org/10.1016/S2213-2600(24)00180-2Lack of Evidence Regarding Markers Identifying Acute Heart Failure in Patients with COPD: An AI-Supported Systematic Review (2024)International journal of chronic obstructive pulmonary disease, 19, 531-541. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Ploumen, E. H., van Beurden, W., van der Palen, J., Doggen, C. & Lenferink, A.https://doi.org/10.2147/COPD.S437899Data inputs and results from AI-supported title and abstract screening "Lack of evidence regarding markers identifying acute heart failure in patients with COPD: an AI-supported systematic review" (2024)[Dataset Types › Dataset]. Zenodo. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Ploumen, E. H., van Beurden, W. J. C., van der Palen, J., Doggen, C. J. M. & Lenferink, A.https://doi.org/10.5281/zenodo.10517334

2023

Facilitators and Barriers of Adherence to Multi-Disease Exacerbation Action Plans in COPD Patients - A Qualitative Study (2023)COPD, 20(1), 262-273. Schrijver, J., Effing, T., Brusse-Keizer, M., van der Palen, J., van der Valk, P. & Lenferink, A.https://doi.org/10.1080/15412555.2023.2240408Evaluation of Exacerbation and Symptom-Free Time in Patients with COPD (2023)COPD, 20(1), 9-17. de Vries, M., Effing, T. W., van der Palen, J., Schrijver, J., van der Valk, P. D. L. P. M. & Lenferink, A.https://doi.org/10.1080/15412555.2022.2136066Exploring Patterns of COPD Exacerbations and Comorbid Flare-Ups (2023)International journal of chronic obstructive pulmonary disease, 18, 2633-2644. van Dijk, S. H. B., Brusse-Keizer, M., Effing, T., van der Valk, P. D. L. P. M., Ploumen, E., Palen, J. v. d., Doggen, C. J. M. & Lenferink, A.https://doi.org/10.2147/COPD.S428960Biomarkers differentiating acute heart failure from COPD exacerbations: not much evidence (2023)European respiratory journal, 62, PA515. van dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Ploumen, E. H., van Beurden, W. J. C., van der Palen, J., Doggen, C. J. M. & Lenferink, A.https://doi.org/10.1183/13993003.congress-2023.PA515Exploring patterns of COPD exacerbations and comorbid flare-ups (2023)European respiratory journal, PA1348. van dijk, S. H. B., Brusse-Keizer, M. G. J., Effing, T., van der valk, P. D. L. P. M., Ploumen, E. H., van der Palen, J., Doggen, C. J. M. & Lenferink, A.https://doi.org/10.1183/13993003.congress-2023.PA1348Predictors of acute exacerbations in COPD: a systematic review (2023)European respiratory journal, PA3641. Bucsán, C. C., Lenferink, A., van dijk, S. H. B., van beurden, W. J. C., van der valk, P. D. L. P. M., Doggen, C. J. M., van der palen, J. & Brusse-Keizer, M. G. J.https://doi.org/10.1183/13993003.congress-2023.PA3641The continuously evolved RE-SAMPLE cohort: predicting outcomes of COPD and comorbidities (2023)[Contribution to conference › Poster] ERS international congress 2023. Lenferink, A., Bucsán, C. C. & Brusse-Keizer, M. G. J.Artificial intelligence in systematic reviews: promising when appropriately used (2023)BMJ open, 13(7). Article e072254. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Palen, J. v. d., Doggen, C. J. M. & Lenferink, A.https://doi.org/10.1136/bmjopen-2023-072254

2022

Differentiating acute heart failure from exacerbations of COPD: An AI-supported literature review (2022)European respiratory journal, 60(Suppl. 66), 1088-1088. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Doggen, C., van der Palen, J. & Lenferink, A.https://doi.org/10.1183/13993003.congress-2022.1088Self-management interventions for people with chronic obstructive pulmonary disease (2022)Cochrane database of systematic reviews (CD-ROM)(1). Article CD002990. Schrijver, J., Lenferink, A., Brusse-Keizer, M., Zwerink, M., van der Valk, P. D. L. P. M., van der Palen, J. & Effing, T. W.https://doi.org/10.1002/14651858.CD002990.pub4Differentiating between acute heart failure and a COPD exacerbation ā€“ Will AI help us in reviewing the literature? (2022)[Contribution to conference › Poster] Dutch Lung Congress 2022. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Doggen, C., van der Palen, J. & Lenferink, A.Distinguishing acute heart failure from COPD exacerbations in COPD patients with acute dyspnoea: Integrating a supportive AI screening tool in the systematic literature review process (2022)[Contribution to conference › Poster] WEON 2022. van Dijk, S. H. B., Brusse-Keizer, M. G. J., Bucsán, C. C., Doggen, C., van der Palen, J. & Lenferink, A.Identifying predictors of acute exacerbations in COPD: a systematic review (2022)[Contribution to conference › Poster] Dutch Lung Congress 2022. Bucsán, C. C., Lenferink, A., van Dijk, S. H. B., van Beurden, W., van der Valk, P. D. L. P. M., Doggen, C., van der Palen, J. & Brusse-Keizer, M. G. J.The influence of adherence to COPD exacerbation action plans on health outcomes (2022)[Contribution to conference › Poster] European Respiratory Society congress 2022. Schrijver, J. J., Effing, T., van Helden, J., Brusse-Keizer, M. G. J., van der Palen, J., van der Valk, P. D. L. P. M. & Lenferink, A.The influence of patientsā€™ adherence to COPD exacerbation action plans on health outcomes (2022)[Contribution to conference › Poster] Dutch Lung Congress 2022. Schrijver, J. J., Effing, T., van Helden, J., Brusse-Keizer, M. G. J., van der Palen, J., van der Valk, P. D. L. P. M. & Lenferink, A.

Research profiles

I am involved in education on epidemiology, methodology and quality in healthcare in different courses (Bachelor and Master Health Sciences, Technical Medicine, Biomedical Engineering):

  • Gezondheid, ziekte en preventie (onderdeel Epidemiologie)Ā 
  • Gezondheidszorgonderzoek (onderdeel project)
  • Optimalisatie van zorg (onderdeel Kwaliteit en veiligheid)
  • Klinisch Wetenschappelijk onderzoek (onderdeel Schrijven van een onderzoeksvoorstel)
  • Bacheloropdracht Gezondheidswetenschappen
  • Quality Management in Healthcare (Master course Health Sciences)
  • Clinical Research Methods (Master course Biomedical Engineering)
  • Clinical Internship Technical Medicine

In addition, I am involved in supervision of Bachelor and Master students (mainly Health Sciences) during their thesis.Ā 

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2023/2024

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