dr. A.R. Vollertsen (Anke)

Engineering & Materials Science

# Cell Culture
# Microfluidics
# Stem Cells

Physics & Astronomy

# Cell Culturing
# Chips
# Circuit Boards
# Fluidic Circuits
# Organs

Faculty of Science and Technology (TNW), Applied Stem Cell Technologies (AST)

My part of the vascular engineering on chip (VESCEL) project is to develop a microfluidic platform for finding optimal conditions for hiPSC differentiation into cardiovascular cells. To achieve this the cells are encapsulated in microdroplets containing variable concentrations of growth factors. This approach will allow more conditions to be tested at higher throughput levels than possible with current standard methods.

Paul, A., van Dorp, T. , Leferink, A. M. , Vollertsen, A. R. , van der Meer, A. , & Odijk, M. (2023). 3D Porous Microfluidic Architectures for Heart-on-Chip. Poster session presented at 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2023, Katowice, Poland.

Broccoli, A. , Vollertsen, A. R., Roels, P., van Vugt, A. , van den Berg, A. , & Odijk, M. (2023). Nanoparticle Printing for Microfluidic Applications: Bipolar Electrochemistry and Localized Raman Sensing Spots. Micromachines, 14(2), Article 453. https://doi.org/10.3390/mi14020453

Vollertsen, A. R., de Winter, S. , van den Berg, A. , Odijk, M. , & van der Meer, A. (2022). An automated chip with a rapid prototypable cell culturing layer for multiplexed organs-on-chips. Paper presented at EUROoCS Annual Meeting 2022, Grenoble, France.

Vollertsen, A. R., Aydogmus, H., Pollet, A., van Meer, B. , van den Berg, A., Mastrangeli, M., Den Toonder, J. , Odijk, M. , & van der Meer, A. (2022). Connecting labs for higher level organ-on-chip systems: integration of a pH sensor and a blood vessel-on-chip on a standardized platform. Paper presented at EUROoCS Annual Meeting 2022, Grenoble, France.

Conceição, F., Sousa, D. M. , Loessberg-Zahl, J. , Vollertsen, A. R., Neto, E., Søe, K., Paredes, J. , Leferink, A., & Lamghari, M. (2022). A metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis. Materials Today Bio, 13, Article 100219. https://doi.org/10.1016/j.mtbio.2022.100219

Bossink, E. G. B. M. , Vollertsen, A. R. , Loessberg-Zahl, J. T. , Meer, A. D. V. D. , Segerink, L. I. , & Odijk, M. (2022). Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications. Microsystems & nanoengineering, 8, Article 54. https://doi.org/10.1038/s41378-022-00378-y

Vollertsen, A. R., Le, K., van den Hil, L., Vermeul, K., van Meer, B. , van den Berg, A., Orlova, V. V., Kumar, V. , Odijk, M. , & van der Meer, A. (2021). Dynamic inflammatory stimulation of hiPSC-endothelial cells in a multiplexed microfluidic chip. Paper presented at EUROoCS Annual conference 2021, Uppsala, Sweden.

Broccoli, A. , Vollertsen, A. R., Roels, P., van Vugt, A. , van den Berg, A. , & Odijk, M. (2021). Local deposition of nanoparticles on a PDMS Microfluidic device. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1381-1382)