TNW-BET-AST

Expertise

  • Chemistry

    • Microfluidics
    • Device
  • Engineering

    • Applications
    • Cleanroom
    • Building Block
  • Physics

    • Utilization
    • Media
    • Organ

Organisations

My part of the vascular engineering on chip (VESCEL) project is to develop a microfluidic platform for finding optimal conditions for hiPSC differentiation into cardiovascular cells. To achieve this the cells are encapsulated in microdroplets containing variable concentrations of growth factors. This approach will allow more conditions to be tested at higher throughput levels than possible with current standard methods.

Publications

2023

3D Porous Microfluidic Architectures for Heart-on-Chip (2023)[Contribution to conference › Poster] 27th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2023. Paul, A., van Dorp, T., Leferink, A. M., Vollertsen, A. R., van der Meer, A. & Odijk, M.Nanoparticle Printing for Microfluidic Applications:: Bipolar Electrochemistry and Localized Raman Sensing Spots (2023)Micromachines, 14(2). Article 453. Broccoli, A., Vollertsen, A. R., Roels, P., van Vugt, A., van den Berg, A. & Odijk, M.https://doi.org/10.3390/mi14020453

2022

An automated chip with a rapid prototypable cell culturing layer for multiplexed organs-on-chips (2022)[Contribution to conference › Paper] EUROoCS Annual Meeting 2022. Vollertsen, A. R., de Winter, S., van den Berg, A., Odijk, M. & van der Meer, A.Connecting labs for higher level organ-on-chip systems: integration of a pH sensor and a blood vessel-on-chip on a standardized platform (2022)[Contribution to conference › Paper] EUROoCS Annual Meeting 2022. Vollertsen, A. R., Aydogmus, H., Pollet, A., van Meer, B., van den Berg, A., Mastrangeli, M., Den Toonder, J., Odijk, M. & van der Meer, A.Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications (2022)Microsystems & nanoengineering, 8. Article 54. Bossink, E. G. B. M., Vollertsen, A. R., Loessberg-Zahl, J. T., Meer, A. D. v. d., Segerink, L. I. & Odijk, M.https://doi.org/10.1038/s41378-022-00378-yA metastasis-on-a-chip approach to explore the sympathetic modulation of breast cancer bone metastasis (2022)Materials Today Bio, 13. Article 100219. Conceição, F., Sousa, D. M., Loessberg-Zahl, J., Vollertsen, A. R., Neto, E., Søe, K., Paredes, J., Leferink, A. & Lamghari, M.https://doi.org/10.1016/j.mtbio.2022.100219

2021

Facilitating implementation of organs-on-chips by open platform technology (2021)Biomicrofluidics, 15(5). Article 051301. Vollertsen, A. R., Vivas, A., van Meer, B., van den Berg, A., Odijk, M. & van der Meer, A. D.https://doi.org/10.1063/5.0063428Automated medium recirculation using macro valves for high flow rates in an endothelial cell culture chip (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1269-1270). Bossink, E. G. B. M., Vollertsen, A. R., Segerink, L., van der Meer, A. & Odijk, M.Local deposition of nanoparticles on a PDMS Microfluidic device (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 1381-1382). Broccoli, A., Vollertsen, A. R., Roels, P., van Vugt, A., van den Berg, A. & Odijk, M.Multiplexed Organ-on-Chips with integrated macro valves for automated cell culture (2021)In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021 (pp. 1385-1386). Bossink, E. G. B. M., Vollertsen, A. R., Hagen , L. P., van der Meer, A., Segerink, L. & Odijk, M.

Research profiles

Address

University of Twente

Horst - Zuidhorst (building no. 28), room 125
De Horst 2
7522 LW Enschede
Netherlands

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