EEMCS-EE-BSS

Annemieke Witteveen is Associate Professor at the Biomedical Signals and Systems (BSS) group and the Personalized eHealth Technology (PeHT) research program. Her research line focusses on building dynamic patient-level models for personalized prediction, monitoring and optimization to support clinical decision making in oncology. See also her interview as a featured scientist.

She studied Technical Medicine and Health Sciences at the University of Twente. After graduation, Annemieke started working as a PhD at the department of Health Technology and Services Research (HTSR) at the University of Twente. Here she worked on individualizing the breast cancer follow-up based on individual time-dependent risk profiles, resulting in a.o. the INFLUENCE nomogram. Her thesis received the prize for best oncology thesis in the Netherlands of 2018/2019.

As PI, Annemieke coordinates several large projects on self-management and decision support for oncology, such as the KWF PARTNR project for optimal cancer-related fatigue treatment and the €6.32M 4TU research program RECENTRE on lifestyle and risk-based monitoring. In 2020 she was awarded a NWO/ZonMW veni grant for researching dynamic models to predict, monitor and make recommendations for the late effects after breast cancer. She was selected as Young Academy member of the University of Twente in 2022. Additionally, Annemieke was awarded with the Royal Academy of Science (KNAW) Early Career Award for innovative and original research (2022), the Henk Stassen Award for connecting medical and technical sciences (2023) and the BOOG (Borstkanker Onderzoek Groep) Young Investigator Award for excellence in breast cancer research (2024). Her expertise in digital oncology research is recognized internationally with invited presentations and participation in multiple juries, and invited participation in an Innovation Mission by the Dutch government on digital health and cancer to India in 2023. She is also Associate Editor of the Journal of Cancer Survivorship. Annemieke is married and has three kids.


WORK EXPERIENCE

2024-present Associate Professor Personalized eHealth Technology for Oncology, Biomedical Signals and Systems (BSS) group, University of Twente         

2025            Visiting researcher, Memorial Sloan Kettering Cancer Center (NY, USA)

2022            Visiting researcher, Harvard T.H. Chan School of Public Health (Harvard University, Boston, USA)

2022            Visiting researcher, Memorial Sloan Kettering Cancer Center (NY, USA)

2021-2023  Assistant Professor, Personalized eHealth Technology for Oncology, Biomedical Signals and Systems (BSS) group, University of Twente    

2019-2023    Coordinator Health and Wellbeing track, Digital Society reseach program (University of Twente/VSNU)

2019-2021    Postdoctoral researcher, Biomedical Signals and Systems group, Personalized eHealth Technology (PeHT) research program (University of Twente)

2015             Visiting researcher, Center for the Science of Health Care Delivery (Mayo Clinic, Rochester, MN)

2013-2018    PhD student, Health Technology and Services Research (University of Twente)

 

GRANTS AND PRIZES

2026 – EEMCS faculty research voucher (€45k, University of Twente)

2025 – Project ‘DynamiCity’ (WP1, €371k, Horizon Europe Cancer Mission)

2024 - BOOG Young Investigator Award for excellence in breast cancer research (Borstkanker Onderzoek Groep) 

2024 - Proof of Concept grant (€152k, Dutch Cancer Society [KWF]) PI

2024 - Catalysator Project on Personalized Lifestyle support for Adolescents and Young Adults with cancer (€93k, RadboudUMC) Co-applicant

2023  -  Henk Stassen Award for bringing medical and technical science together (€1k, Biomedical Engineering conference)

2023 - Educational improvement grant (€15k, EEMCS faculty University of Twente) 

2022 Early Career Award  (€15k, Royal Academy of Science [KNAW])

2022 - 4TU program RECENTRE: Risk-based lifEstyle Change: daily-lifE moNiToring and REcommendations (€6.32M, 4TU) – Project Leader

2022 - Selected as member of the Young Academy (YA@UT)

2021  -  Rene Vogels Foundation Travel Grant, Harvard (USA) (€5k, Dutch Society for Oncology, NVvO)

2021 – Project sponsoring ‘Better informed, better care: Optimizing cancer information based on individual patient preferences’ (€324k, Pfizer/Roche/UT) – Project Leader

2020 - Veni Grant ‘Towards a higher quality of life after cancer: dynamic prediction, monitoring and recommendations for late effects after breast cancer’ (€250k, Dutch Research Council [NOW]/ Netherlands Organisation for Health Research and Development [ZonMW]) – Project Leader

2019 - Best Thesis in Oncology Prize of the Netherlands and Belgium in 2018/2019 (Dutch and Flemish organizations for medical oncology, NVMO/BSMO)

2019  Technology for Oncology Grant (€735k, Dutch Research Council [NWO] and Dutch Cancer Society [KWF]) – Project Leader

2019  -  Research Voucher (€50k, ZiekenhuisGroep Twente hospitals) – Project Leader

2016  -  Tech4People Travel Grant, Sorbonne University (France) (€1k, University of Twente)

2015  -  Rene Vogels Foundation Travel Grant, Mayo Clinic (USA) (€4k, Dutch Society for Oncology, NVvO)

 

NETWORKS

Member of professional societies:
· Vereniging voor Epidemiologie (VvE)
· International Society for Pharmacoeconomics and Outcomes Research (ISPOR)·
· Society for Medical Decision Making (SMDM)

 

TEACHING

Annemieke was involved in the bachelor courses Klinische Epidemiologie
(Gezondheidswetenschappen) and Epidemiologie, Statistiek en MTA (Technische
Geneeskunde), and the master course Clinical Efficacy and MTA (Health Sciences). Also,
Annemieke supervised several master students with their thesis. In 2016 and 2017 she was organizer and course leader of the University of Twente CuriousU summer school track The Future of Health Technology. In 2019 she started another course on Personalized eHealth Technology. She is developing a new master course on eHealth for the Technical Medicine curriculum.

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Recurrent Disease
    • Follow up
    • Cancer-Related Fatigue
    • Therapeutic Procedure
  • Psychology

    • Treatment
  • Nursing and Health Professions

    • Fatigue

Organisations

Publications

Jump to: 2026 | 2025

2026

Toward targeted exercise and dietary interventions for adolescents and young adults with cancer (2026)In ISEO Inaugural Conference 2026. Kenkhuis, M. F., Hermens, R. P. M. G., Witteveen, A., Kaal, S., Husson, O. & Buffart, L. M.Who is missing?: A scoping review on the representation of different populations in studies assessing the validity of consumer wearable PPG-based measurements (2026)JMIR mHealth and uHealth (Accepted/In press). Schipper, R., Fatime, O. D., Roosink, M., Winkens, L., John, A., Hazebroek, E., Witteveen, A. & Berendsen, A.Vervroegd ontslag met thuismonitoring na minor leverchirurgie (2026)[Contribution to conference › Poster] Chirurgendagen 2026. Abdulahad, D., Sprakel, J., Liem, M. S. L., Witteveen, A., Waanders, I. & Lips, D. J.The Personalized cAnceR TreatmeNt and caRe (PARTNR) project: Optimizing intervention recommendations for breast cancer-related fatigue (2026)[Contribution to conference › Poster] TechMed Research Day 2026. Wijlens, K. A. E., Bode, C., Siesling, S., Vollenbroek-Hutten, M. M. R. & Witteveen, A.Automatic noise detection in remotely monitored pacemakers and implantable cardiac defibrillators using a deep learning model (2026)In Digital Health and AI (Submitted). van Krimpen, L., John, A., Thyagarajah, A., van der Zande, J., Witteveen, A., Sacristan, B., Duchateau, J., Dubois, R., Bordachar, P., Pioux, S. & Strik, M.Comparing Unsupervised Change Point Detection Methods for Detecting Postoperative Complications in Home-Monitored Cancer Patients (2026)Medical decision making (Submitted). Fatime, O. D., Waanders, I., Lips, D. J., Nane, G. F., van Keulen, M., Witteveen, A. & John, A.Earlier Detection of Anastomotic Leakage with a Remote Patient Monitoring-Supported Early-Discharge Pathway after Elective Colorectal Surgery: A Retrospective Cohort Study (2026)Annals of Gastroenterological Surgery (In preparation). Dohuky, N., Waanders, I., Stindt, T., Lips, D. J., Daams, F. & Witteveen, A.Early detection of complications using smartphone-based symptom monitoring after colorectal cancer surgery (2026)Medical decision making (Accepted/In press). Waanders, I., Bickes, J., Kwast, A. B. G., Bretveld, R., Lips, D. J. & Witteveen, A.Prognostic value of baseline PSMA PET/CT for survival in synchronous metastatic hormone-sensitive prostate cancer: Towards redefining low- and high-volume disease (2026)European radiology (Submitted). Kleiburg, F., Heijmen, L., Witteveen, A., van Duuren, K., Zuidgeest, P., Smit, F., Oei, L.-F. & van der Hulle, T.The relation between self-reported cancer-related fatigue after breast cancer and wearable data: future chances for unobtrusive monitoring (2026)Medical decision making (Accepted/In press). Wijlens, K. A. E., Schrover, T., Siesling, S., Bode, C. & Witteveen, A.

2025

Who is missing?: A scoping review on the representation of different populations in studies assessing the validity of consumer wearable PPG-based measurements (2025)[Working paper › Preprint]. JMIR Publications. Schipper, R., Fatime, O. D., Roosink, M., Winkens, L., John, A., Hazebroek, E., Witteveen, A. & Berendsen, A.https://doi.org/10.2196/preprints.87324Holistic assessment of cancer-related fatigue after breast cancer: Working towards monitoring and personalized treatment advice (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Wijlens, K. A. E.https://doi.org/10.3990/1.9789036567725Breast cancer-related fatigue risk and intervention recommendations: What can and cannot be personalised? (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Beenhakker, L.https://doi.org/10.3990/1.97890365684252405P PSMA PET/CT-based risk stratification in synchronous metastatic hormone-sensitive prostate cancer (2025)Annals of oncology, 36(Suppl. 2), S1224. Kleiburg, F., Heijmen, L., Witteveen, A., van Duuren, K., Zuidgeest, P., Smit, F., de Geus-Oei, L.-F. & Van Der Hulle, T.https://doi.org/10.1016/j.annonc.2025.08.3021A comparison of variable selection methods and predictive models for postoperative bowel surgery complications (2025)[Working paper › Preprint]. ArXiv.org. Şahin, Ö., Kwast, A., Witteveen, A. & Nane, T.https://doi.org/10.48550/arXiv.2507.22771Unsupervised Detection of Postoperative Complications in Home-Monitored Patients: Preliminary Results (2025)In 2025 IEEE International Symposium on Medical Measurements and Applications (MeMeA) (IEEE International Workshop on Medical Measurement and Applications (MEMEA); Vol. 2025). IEEE. Fatime, O. D., Waanders, I., Lips, D. J., Nane, G. F., van Keulen, M., Witteveen, A. & John, A.https://doi.org/10.1109/MeMeA65319.2025.11068044Coming to optimal cancer-related fatigue intervention recommendations after breast cancer: the personalized cancer treatment and care (partnr) project (2025)Supportive care in cancer, 33. Article 583. Witteveen, A., Wijlens, K. A. E., Beenhakker, L., Siesling, S., Bode, C. & Vollenbroek-Hutten, M. M. R.https://link.springer.com/article/10.1007/s00520-025-09559-7Predictors of any or serious postoperative complications after colorectal and small bowel surgeries (2025)Supportive care in cancer, 33. Article 583. Witteveen, A., Şahin, Ö., Kwast, A. B. G. & Nane, G. F.https://link.springer.com/article/10.1007/s00520-025-09559-7Reporting, representation and subgroup analysis in studies assessing consumer wearable validity: a scoping review (2025)[Contribution to conference › Abstract] 14th Supporting Health by Technology Conference 2025. Schipper, R., Fatime, O. D., Roosink, M., Winkens, L., John, A., Witteveen, A., Hazebroek, E. & Berendsen, A.Unsupervised Change Point Detection for Early Complication Identification in Post-Surgical Oncology Patients (2025)[Contribution to conference › Abstract] 14th Supporting Health by Technology Conference 2025. Fatime, O. D., Waanders, I., Lips, D. J., Witteveen, A., Nane, G. F., van Keulen, M. & John, A.A holistic profile for cancer-related fatigue for women with breast cancer–a qualitative study (2025)Psychology & health, 40(6), 1037-1061. Wijlens, K. A. E., Beenhakker, L., Witteveen, A., Siemerink, E. J. M., Jansen, L., Gernaat, C., Schellekens, M. P. J., Siesling, S., Vollenbroek-Hutten, M. M. R. & Bode, C.https://doi.org/10.1080/08870446.2023.2289457Working toward Personalized Intervention Advice: A Survey Study on Preference Heterogeneity in Patients with Breast Cancer–Related Fatigue (2025)MDM Policy and Practice, 10(1). Beenhakker, L., Wijlens, K. A. E., Bode, C., Vollenbroek-Hutten, M. M. R., Siesling, S., van Til, J. & Witteveen, A.https://doi.org/10.1177/23814683241309676Development of machine learning models to predict cancer-related fatigue in Dutch breast cancer survivors up to 15 years after diagnosis (2025)Journal of cancer survivorship, 19(2), 580-593. Beenhakker, L., Wijlens, K. A. E., Witteveen, A., Heins, M., Korevaar, J. C., de Ligt, K. M., Bode, C., Vollenbroek-Hutten, M. M. R. & Siesling, S.https://doi.org/10.1007/s11764-023-01491-1Missing Data of the Philips HealthDot: insights into monitoring at home and level of physical activity (2025)[Contribution to conference › Abstract] 10th Dutch Biomedical Engineering Conference, BME 2025. Waanders, I., Vassen, H., Lips, D. J., Witteveen, A. & John, A.Dynamic Predictive Models for Side Effects Following Cancer or Cancer Treatment: A Systematic Review (2025)[Contribution to conference › Abstract] 10th Dutch Biomedical Engineering Conference, BME 2025. Fatime, O. D., Schipper, R., Berendsen, A., Nane, G. F., van Keulen, M., Witteveen, A. & John, A.

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University of Twente

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De Horst 2
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University of Twente

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