prof.dr. A.D. van der Meer (Andries)

Full Professor
TNW-BET-AST
Horst - Zuidhorst 116
andries.vandermeer@utwente.nl
+31534898064
Business card

Prof. Dr. Andries D. van der Meer is Professor of Microphysiological Systems at the Department of Bioengineering Technologies in the Faculty of Science and Technology of the University of Twente, The Netherlands.

His primary research interest is the design, development and application of Organs-on-Chips. Organs-on-Chips are microengineered laboratory devices with cultured living tissue, which recapitulate distinct functions of human organs. Organs-on-Chips can be used to understand human diseases and discover new treatments. Some of the models that Van der Meer works on are the Retina-on-Chip, Lung-on-Chip and Heart-on-Chip, and his group has a specific focus on the realistic integration of blood vessels in Organs-on-Chips.

From 2013 to 2015, Dr. Van der Meer worked as a Senior Research Fellow at Harvard Medical School and the Wyss Institute for Biologically Inspired Engineering of Harvard University, Cambridge, MA, USA. He actively developed Organ-on-Chip models of the blood-brain barrier and the lung alveolus for the Defense Advanced Research Projects Agency (DARPA) Microphysiological Systems program and coordinated a collaborative project between the Wyss Institute Organ-on-Chip start-up company Emulate, Inc. and Janssen Pharmaceuticals.

Before joining Harvard University, he was a Post-Doctoral Fellow at Prof. Albert van den Berg’s BIOS/Lab-on-a-Chip group of the University of Twente, The Netherlands. During that time, he also served as an Assistant Coordinator for the project ‘Beyond Borders: Organs-on-Chips’ of the Dutch Royal Academy (KNAW). This project led to the founding of the Dutch Human Organ and Disease Model Technologies (hDMT) Organ-on-Chip consortium, for which Dr. Van der Meer is the representative of the University of Twente. Van der Meer is currently the President of the European Organ-on-Chip Society (EUROoCS) and the Chair of the CEN CENELEC Focus Group for Standardization for Organ-on-Chip (FGOoC).

Dr. Van der Meer obtained his Ph.D. in Biomedical Engineering from the University of Twente, The Netherlands in 2010, and received his M.Sc. degree in Medical Biology from the University of Groningen, The Netherlands in 2005.

Expertise

  • Medicine and Dentistry

    • Organ
    • Endothelial Cell
    • In Vitro
    • Vascular Bundle
    • Thrombosis
    • Cells

  • Biochemistry, Genetics and Molecular Biology

    • Cell Culture
    • Membrane

Organisations

  • Developing microfluidic 'organ-on-chip' technology
  • Advanced in vitro models of human organs and tissues
  • Focus on vascular biology and thrombosis
  • Human stem cell technology
  • Applications in drug development and precision medicine
  • 3R - 'Replacement, Reduction, Refinement' of animal testing

Publications

2024

Standardizing designed and emergent quantitative features in microphysiological systems (2024)Nature Biomedical Engineering, 8, 941-962. Nahon, D., Moerkens, R., Aydogmus, H., Lendemeijer, B., Martínez-Silgado, A., Stein, J., Dostanić, M., Frimat, J.-P., Gontan, C., de Graaf, M. N. S., Hu, M., Kasi, D., Koch, L. S., Le, K., Lim, S., Middelkamp, H. H. T., Mooiweer, J., Montreux-Ragot, P., Niggl, E., … Mummery, C. L.https://doi.org/10.1038/s41551-024-01236-0Photoannealing of Microtissues Creates High-Density Capillary Network Containing Living Matter in a Volumetric-Independent Manner (2024)Advanced materials, 36(28). Article 2308949. Schot, M., Becker, M., Paggi, C. A., Gomes, F., Koch, T., Gensheimer, T., Johnbosco, C., Nogueira, L. P., van der Meer, A., Carlson, A., Haugen, H. & Leijten, J.https://doi.org/10.1002/adma.202308949Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells (2024)PLoS ONE, 19(6). Article e0305906. van der Pol, K. H., Koenderink, J., van den Heuvel, J. J. M. W., van den Broek, P., Peters, J., van Bunningen, I. D. W., Pertijs, J., Russel, F. G. M., Koldenhof, J., Morshuis, W. J., van Drongelen, J., Schirris, T. J. J., van der Meer, A. & Rongen, G. A.https://doi.org/10.1371/journal.pone.0305906

Research profiles

  • Molecular biology and cell biology
  • Biomedical engineering
  • Stem cell technology

Affiliated study programs

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2023/2024

Address

University of Twente

Horst - Zuidhorst (building no. 28), room 116
De Horst 2
7522 LW Enschede
Netherlands

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