Prof. Dr. Andries D. van der Meer is Professor of Microphysiological Systems at the Department of Bioengineering Technologies in the Faculty of Science and Technology of the University of Twente, The Netherlands.

His primary research interest is the design, development and application of Organs-on-Chips. Organs-on-Chips are microengineered laboratory devices with cultured living tissue, which recapitulate distinct functions of human organs. Organs-on-Chips can be used to understand human diseases and discover new treatments. Some of the models that Van der Meer works on are the Retina-on-Chip, Lung-on-Chip and Heart-on-Chip, and his group has a specific focus on the realistic integration of blood vessels in Organs-on-Chips.

From 2013 to 2015, Dr. Van der Meer worked as a Senior Research Fellow at Harvard Medical School and the Wyss Institute for Biologically Inspired Engineering of Harvard University, Cambridge, MA, USA. He actively developed Organ-on-Chip models of the blood-brain barrier and the lung alveolus for the Defense Advanced Research Projects Agency (DARPA) Microphysiological Systems program and coordinated a collaborative project between the Wyss Institute Organ-on-Chip start-up company Emulate, Inc. and Janssen Pharmaceuticals.

Before joining Harvard University, he was a Post-Doctoral Fellow at Prof. Albert van den Berg’s BIOS/Lab-on-a-Chip group of the University of Twente, The Netherlands. During that time, he also served as an Assistant Coordinator for the project ‘Beyond Borders: Organs-on-Chips’ of the Dutch Royal Academy (KNAW). This project led to the founding of the Dutch Human Organ and Disease Model Technologies (hDMT) Organ-on-Chip consortium, for which Dr. Van der Meer is the representative of the University of Twente. Van der Meer is past past-President and board member of the European Organ-on-Chip Society (EUROoCS) and past-Chair of the CEN CENELEC Focus Group for Standardization for Organ-on-Chip (FGOoC).

Dr. Van der Meer obtained his Ph.D. in Biomedical Engineering from the University of Twente, The Netherlands in 2010, and received his M.Sc. degree in Medical Biology from the University of Groningen, The Netherlands in 2005.

Organisations

  • Developing microfluidic 'organ-on-chip' technology
  • Advanced in vitro models of human organs and tissues
  • Human stem cell technology
  • Applications in drug development and precision medicine
  • 3R - 'Replacement, Reduction, Refinement' of animal testing

Publications

2025

A workflow integrating organ-on-chip culture and correlative 3D light and electron microscopy for microtissue analysis (2025)Scientific reports, 15(1). Article 43666. Schaart, J. M., Wasserberg, D., Cruz, M. A. E., Kea-te Lindert, M., van der Meijden, R. H. M., Roverts, R., Debera, N., Lu, M. P., Rouwkema, J., Nijhuis, W. H., van der Meer, A. D., Jonkheijm, P., Sommerdijk, N. & Akiva, A.https://doi.org/10.1038/s41598-025-27587-5Mapping cardiac drug transport: In vitro assessment of cardiac P-glycoprotein function with [18F]MC225 by using µ-engineered heart tissues (2025)European Heart Journal Open, 5(6). Article oeaf150. Liu, W., Dannenberg, M., Mossel, P., Cai, Z., Farinha Antunes, I., Sijbesma, J., Kwizera, C., Cao, L., van der Meer, A., Passier, R., Slart, R. H. J. A., Schwach, V. & Luurtsema, G.https://doi.org/10.1093/ehjopen/oeaf150Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time-Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion (2025)Advanced Materials Technologies, 10(21). Article e00194. Gensheimer, T., Fuchs, S., de Heus, L. E., Vermeul, K., Mayr, T. & van der Meer, A.https://doi.org/10.1002/admt.202500194

Research profiles

Address

University of Twente

Horst - Zuidhorst (building no. 28), room 116
De Horst 2
7522 LW Enschede
Netherlands

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