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dr. A.D. van der Meer (Andries)

Assistant Professor

About Me

Andries van der Meer has a Master's degree in Medical Biology from the University of Groningen, and he received his Ph.D. in 2010 on the thesis 'Microfluidic Technology in Vascular Research: The Endothelial Response to Shear Stress', carried out under supervision of prof. dr. Jan Feijen and prof. dr. István Vermes of the Faculty of Science and Technology of the University of Twente. Between 2010 and 2015, dr. Van der Meer trained as a Post-Doctoral Fellow and later as a Senior Research Fellow at the University of Twente in the group of prof. dr. Albert van den Berg, and at the Wyss Institute for Biologically Inspired Engineering of Harvard University in the group of Don Ingber, M.D., Ph.D. In 2015, dr. Van der Meer joined the University of Twente as a Tenure Track Assistant Professor in the department of Applied Stem Cell Technologies. He coordinates the University of Twente Strategic Research Orientation ‘Organs-on-Chips’, he is the university representative for the hDMT Organ-on-Chip Consortium, and he heads his own research group in which he focuses on developing innovative organs-on-chips for application in the fields of vascular biology and thrombosis.

Expertise

Microfluidics
In Vitro Techniques
Thrombosis
Blood Vessels
Endothelial Cells
Technology
Blood-Brain Barrier
Brain

Research

  • Developing microfluidic 'organ-on-chip' technology
  • Advanced in vitro models of human organs and tissues
  • Focus on retina, eye disease, vascular biology and thrombosis
  • Human stem cell technology
  • Applications in drug development and precision medicine
  • 3R - 'Replacement, Reduction, Refinement' of animal testing

Publications

Recent Articles
Jain, A., Barrile, R., van der Meer, A. D., Mammoto, A., Mammoto, T., De Ceunynck, K., ... Ingber, D. E. (2018). Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clinical pharmacology & therapeutics, 103, 332-340. DOI: 10.1002/cpt.742
Tibbe, M. P., van der Meer, A. D., van den Berg, A., Stamatialis, D., & Segerink, L. (2018). Membranes for Organs-on-Chips. In D. Stamatialis (Ed.), Biomedical Membranes and (Bio)Artificial Organs (pp. 295-321). (World Scientific Series in Membrane Science and Technology: Biological and Biomimetic Applications, Energy and the Environment: ; Vol. 2). World Scientific. DOI: 10.1142/9789813223974_0011
Molloy, C. P., Yao, Y., Kammoun, H., Bonnard, T., Hoefer, T., Alt, K., ... Westein, E. (2017). Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation. Journal of thrombosis and haemostasis, 15(5), 972-982. DOI: 10.1111/jth.13666
van der Helm, M. W., Henry, O., Hamkins-Indik, T., Cronce, M., Leineweber, W., Odijk, M., ... Segerink, L. (2017). Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1114-1115). Savannah: Chemical and Biological Microstystems Society.
Jain, A., van der Meer, A. D., Papa, A-L., Barrile, R., Lai, A., Schlechter, B. L., ... Ingber, D. E. (2016). Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomedical microdevices, 18(73), 73-. [73]. DOI: 10.1007/s10544-016-0095-6
Herland, A., van der Meer, A. D., Fitzgerald, E. A., Park, T-E., Sleeboom, J. J. F., & Ingber, D. E. (2016). Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip. PLoS ONE, 11(3), -. [e0150360]. DOI: 10.1371/journal.pone.0150360

UT Research Information System

Google Scholar Link

Education

  • Molecular biology and cell biology
  • Biomedical engineering
  • Stem cell technology

Affiliated Study Programmes

Bachelor

Master

Courses

Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst (building no. 28), room 127
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst  127
P.O. Box 217
7500 AE Enschede
The Netherlands

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