C. Cofino Fabres MSc (Carla)

PhD Candidate


Medicine & Life Sciences
Atrial Fibrillation
Cardiac Myocytes
In Vitro Techniques
Muscle Cells
Pluripotent Stem Cells
Preclinical Drug Evaluations
Retinoic Acid Receptor Alpha


My main goal is to identify new key molecular pathways and regulatory elements for cardiac subtype specification and enhance its maturation in order to improve the in vitro procedures to generate cells for cardiovascular disease modeling and therapeutic applications. 

This project is part of the Netherlands Organization for Health Research and Development - ZonMW. 


Harlaar, N., Dekker, S. O., Zhang, J., Snabel, R. R., Veldkamp, M. W., Verkerk, A. O. , Fabres, C. C. , Schwach, V., Lerink, L. J. S., Rivaud, M. R., Mulder, A. A., Corver, W. E., Goumans, M. J. T. H., Dobrev, D., Klautz, R. J. M., Schalij, M. J., Veenstra, G. J. C. , Passier, R., van Brakel, T. J., ... de Vries, A. A. F. (2022). Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Nature Biomedical Engineering, 6, 389-402. https://doi.org/10.1038/s41551-021-00827-5
Ribeiro, M. C. , Rivera-Arbelaez, J. M. , Cofino-Fabres, C. , Schwach, V. , Slaats, R. H. , ten Den, S. A. , Vermeul, K. , van den Berg, A., Perez-Pomares, J. M. , Segerink, L. I., Guadix, J. A. , & Passier, R. (2022). A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues. Journal of Personalized Medicine, 12(2), [214]. https://doi.org/10.3390/jpm12020214

Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst (building no. 28), room 115
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst  115
P.O. Box 217
7500 AE Enschede
The Netherlands