prof.dr. D.W. Donker MD (Dirk)

Full Professor

About Me

In March 2021, I was appointed on the chair of Cardiovascular and Respiratory Physiology (CRPH) at the faculty of Science and Technology of the University of Twente.

The chair is specifically intended to stimulate translational research and education. This, in order to allow patients and health care professionals to maximally benefit from the latest ingenious technologies integrated into modern clinical practice. In this sense, I consider my academic-clinical ambitions equally important as my dedication to professional education in technical medicine, biomedical technology and medicine.

I am indebted for the opportunity to combine my professorship with a position as a senior staff member and intensivist-cardiologist in the Intensive Care Centre at the University Medical Centre Utrecht.

The care for patients with acute and life-threatening disease remains complex and challenging. My experience from daily critical care underlines my enduring personal aspiration to advance technological innovation and improve clinical practice.  

After attending medical school in Essen, Germany, I received my PhD thesis entitled ‘Cardiac mechanomyopathy - integrating the picture from cell to beating heart’ from Maastricht University in 2008. Meanwhile, I completed my medical specialization in Cardiology followed by Intensive Care training at the Maastricht University Medical Center. In 2013, I joined the staff of the Intensive Care Centre at the University Medical Centre Utrecht and in 2019, I expanded my academic-clinical experience in Cardiological Critical Care at the La Pitié-Salpêtrière hospital in Paris.

My clinical, educational and research interests center around complex cardiovascular and respiratory care. In recent years, I focused on cardiac and pulmonary extracorporeal life support to optimize its clinical use and expand practice-relevant mechanistic insights. My affinity with echocardiography and an inspiring collaboration on patient-specific computer simulation through the years has greatly enlarged my comprehensive physiological understanding and contributes importantly to my work as a physician.

I am actively involved in national and international scientific organizations in the field, collaborate with many dedicated clinicians, researchers and companies, authored many scientific publications and provided numerous presentations. All this, to foster professionals’ enthusiasm and strive to realize a continuing translation of technology, where it is most urgently needed: at the bedside of the individual patient.


Medicine & Life Sciences
Cardiogenic Shock
Computer Simulation
Critical Illness
Extracorporeal Membrane Oxygenation
Heart Failure
Heart-Assist Devices

Ancillary Activities

  • University Medical Center Utrecht
  • Getinge Maquet Critical Care AB
    Consultancy research
  • Sonion BV
    Contract research


Mulder, M. P. , Fresiello, L., Rumindo, K., Jalde, F., Hallbäck, M., Maksuti, E. , & Donker, D. W. (Accepted/In press). A computational platform for virtual patient trials of fluid responsiveness prediction in septic shock phenotypes. Abstract from ESICM LIVES Forum Conference 2023, Utrecht, Netherlands.
van der Zande, J., Strik, M., Dubois, R., Ploux, S., Abu Alrub, S., Caillol, T., Nasarre, M. , Donker, D. W. , Oppersma, E., & Bordachar, P. (2023). Using a Smartwatch to Record Precordial Electrocardiograms: A Validation Study. Sensors (Basel, Switzerland), 23(5), [2555]. https://doi.org/10.3390/s23052555
Adriaansen, E. J. M., Hermens, J. A. J., Broome, M., Pladet, L., Dubois, E. , Donker, D. W., & Meuwese, C. L. (2023). Cardiac tamponade during venoarterial extracorporeal membrane oxygenation: a case report. Journal of Medical Case Reports, 17(1), [50]. https://doi.org/10.1186/s13256-022-03741-9
Saeed, D., Loforte, A., Morshuis, M., Schibilsky, D., Zimpfer, D., Riebandt, J., Pappalardo, F., Attisani, M., Rinaldi, M., Haneya, A., Ramjankhan, F. , Donker, D. W., Jorde, U. P., Pacini, D., Otto, W., Stein, J., Lewin, D., Jawad, K., Wieloch, R., ... Potapov, E. (2023). Stroke Complications in Patients Requiring Durable Mechanical Circulatory Support Systems after Extracorporeal Life Support. ASAIO Journal, 69(2), 145-150. https://doi.org/10.1097/MAT.0000000000001732
Suverein, M. M., Delnoij, T. S. R., Lorusso, R., Brandon Bravo Bruinsma, G. J., Otterspoor, L., Elzo Kraemer, C. V., Vlaar, A. P. J., van der Heijden, J. J., Scholten, E., den Uil, C., Jansen, T., van den Bogaard, B., Kuijpers, M., Lam, K. Y., Montero Cabezas, J. M., Driessen, A. H. G., Rittersma, S. Z. H., Heijnen, B. G., Dos Reis Miranda, D., ... van de Poll, M. C. G. (2023). Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest. The New England journal of medicine, 388(4), 299-309. https://doi.org/10.1056/NEJMoa2204511
Pladet, L. C. A., Barten, J. M. M., Vernooij, L. M., Kraemer, C. V. E., Bunge, J. J. H., Scholten, E., Montenij, L. J., Kuijpers, M. , Donker, D. W., Cremer, O. L., & Meuwese, C. L. (2023). Prognostic models for mortality risk in patients requiring ECMO. Intensive care medicine, 49, 131-141. https://doi.org/10.1007/s00134-022-06947-z
Cvetkovic, M., Chiarini, G., Belliato, M., Delnoij, T., Zanatta, P., Taccone, F. S., dos Reis Miranda, D., Davidson, M., Matta, N., Davis, C., IJsselstijn, H., Schmidt, M., Broman, L. M. , Donker, D. W., Vlasselaers, D., David, P., Di Nardo, M., Muellenbach, R. M., Mueller, T., ... Hoskote, A. (2023). International survey of neuromonitoring and neurodevelopmental outcome in children and adults supported on extracorporeal membrane oxygenation in Europe. Perfusion, 38(2), 245-260. https://doi.org/10.1177/02676591211042563
Broomé, M., Carlsson, M., Frieberg, P., Hakacova, N. , & Donker, D. W. (2022). Cardiovascular Simulation as a Decision Support Tool. In Modelling Congenital Heart Disease (pp. 261- 271) https://doi.org/10.1007/978-3-030-88892-3_26

UT Research Information System

Courses Academic Year  2022/2023

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses Academic Year  2021/2022

Contact Details

Visiting Address

University of Twente
Drienerlolaan 5
7522 NB Enschede
The Netherlands

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Mailing Address

University of Twente
P.O. Box 217
7500 AE Enschede
The Netherlands