A chemist by training, I strive to understand, and eventually control, molecular interactions between surfaces, (bio)molecules and their surrounding medium. My research in the past decade has focused on developing (bio-)chemical strategies to enable analytical assays using biomolecules on surfaces, specifically, inside microfluidic chips. I was involved in the development of
- synthesis and characterization of androgen competitors binding to androgen receptor
- goldnanoparticle sandwich immuno assays detection via spectral imaging - fabrication of orientationally controlled protein patterns and their photophysical characterisation
- on-chip immunophenotyping in resource poor settings
- fabrication of chips via inkjetprinting and characterisation via fluorescence imaging
- surface engineering for epigenetics-based non-invasive early cancer diagnostics on chip
I am currently holding a part-time post-doctoral research position at the Faculty of TNW at AST and MnF groups, working on developing an organoid-on-a-chip device.
Since 2020, I am working part-time at LipoCoat BV, Enschede, The Netherlands, as Senior Researcher working on coating technology for medical devices.
Expertise
Chemistry
- Surface
- Deoxyribonucleic Acid
- Molecule
- Assay
- Gelatin
Engineering
- Robot
Biochemistry, Genetics and Molecular Biology
- Surface Property
- Protein
Organisations
Publications
2025
Dynamic Modeling of a Magnetic Video Capsule for Enhanced Navigation in the Gastrointestinal Tract (2025)[Contribution to conference › Paper] 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2025. Bester, E. V., Chen, W., Kobus van der Mijle Meijer, J., Ligtenberg, L.-J. W., Mulder , I., Liefers, H. R., Goulas, C., Wasserberg, D., Jonkheijm, P., Warlé, M., Mersha, A. Y., Braat, H. & Khalil, I. S. M.https://doi.org/10.1109/EMBC58623.2025.11253554Author Correction: Ex vivo validation of magnetically actuated intravascular untethered robots in a clinical setting: Ex vivo validation of magnetically actuated intravascular untethered robots in a clinical setting (Communications Engineering, (2024), 3, 1, (68), 10.1038/s44172-024-00215-2) (2025)Communications Engineering, 4. Article 16. Ligtenberg, L.-J. W., Rabou, N. C. A., Goulas, C., Duinmeijer, W. C., Halfwerk, F. R., Arens, J., Lomme, R., Magdanz, V., Klingner, A., Rot, E. A. M. K., Nijland, C. H. E., Wasserberg, D., Liefers, H. R., Jonkheijm, P., Susarrey-Arce, A., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1038/s44172-025-00353-1Swimming dynamics of screw-shaped untethered magnetic robots in confined spaces (2025)Nonlinear Dynamics, 113(21), 29197-29213. De Jongh, L., Klingner, A., Ligtenberg, L.-J. W., De Boer, M. C. J., van der Jooij, J., Lomme, R. M., Wasserberg, D., Liefers, H. R., Jonkheijm, P., Warlé, M. C. & Khalil, I. S. M.https://doi.org/10.1007/s11071-025-11646-7OPSALC: On-Particle Solvent-Assisted Lipid Coating to Create Erythrocyte Membrane-like Coatings with Improved Hemocompatibility (2025)ACS Applied Materials and Interfaces, 17(12), 18179-18193. Fernandes Gomes, F. L., Wasserberg, D., Edelbroek, R., van Weerd, J., Jonkheijm, P. & Leijten, J.https://doi.org/10.1021/acsami.5c02103Wireless mechanical and hybrid thrombus fragmentation of ex vivo endovascular thrombosis model in the iliac artery (2025)Applied physics reviews, 12(1). Article 011416. de Boer, M. C. J., Ligtenberg, L.-J. W., Mulder, I., Goulas, C., Klingner, A., Lomme, R., Rot, E. A. M. K., Wasserberg, D., Lu, Y., Liefers, R., van der Mijle Meijer, J. K., Tuijthof, G. J. M., Ben Ami, D., Sadeh, U., Shoseyov, O., Leclerc, J., Becker, A. T., Jonkheijm, P., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1063/5.0233677
2024
X-Ray-Guided Magnetic Fields for Wireless Control of Untethered Magnetic Robots in Cerebral Vascular Phantoms (2024)In 2024 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2024 (pp. 4624-4629) (IEEE International Conference on Intelligent Robots and Systems). IEEE. Ligtenberg, L. J. W., De Boer, M. C. J., Mulder, I., Lomme, R., Wasserberg, D., Klein Rot, E. A. M., Ben Ami, D., Sadeh, U., Liefers, H. R., Shoseyov, O., Jonkheijm, P., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1109/IROS58592.2024.10802534Ex vivo validation of magnetically actuated intravascular untethered robots in a clinical setting (2024)Communications Engineering, 3. Article 68. Ligtenberg, L.-J. W., Rabou, N. C. A., Goulas, C., Duinmeijer, W., Halfwerk, F. R., Arens, J., Lomme, R., Magdanz, V., Klingner, A., Klein Rot, E. A. M., Nijland, C. H. E., Wasserberg, D., Liefers, H. R., Jonkheijm, P., Susarrey-Arce, A., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1038/s44172-024-00215-2X-Ray-Guided Robotic Platform for Remote Control of Untethered Magnetic Robots Targeting Blood Clots in the Iliac Artery (2024)In 2024 10th IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob) (pp. 526-531) (Proceedings IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob); Vol. 2024). IEEE. Ligtenberg, L.-J. W., de Jongh, L., Liefers, H. R., Wasserberg, D., Klein Rot, E. A. M., Ben Ami, D., Sadeh, U., Lomme, R. M., Tuijthof, G. G. M., Shoseyov, O., Jonkheijm, P., Warlé, M. & S.M. Khalil, I.https://doi.org/10.1109/BioRob60516.2024.10719845Electrochemical Sensing with Spatially Patterned Pt Octahedra Electrodes (2024)Advanced Materials Technologies, 9(5). Article 2300878. Jonker, D., Eyovge, C., Berenschot, E., Di Palma, V., Wasserberg, D., Michel-Souzy, S., Jonkheijm, P., Krol, S., Gardeniers, H., Creatore, M., Tas, N. & Susarrey-Arce, A.https://doi.org/10.1002/admt.202300878Electrochemical Sensing with Spatially Patterned Pt Octahedra Electrodes (Adv. Mater. Technol. 5/2024): Back Cover Graphical Abstract (2024)Advanced Materials Technologies, 9(5). Jonker, D., Eyovge, C., Berenschot, E., Di Palma, V., Wasserberg, D., Michel‐Souzy, S., Jonkheijm, P., Krol, S., Gardeniers, H., Creatore, M., Tas, N. & Susarrey‐Arce, A.https://doi.org/10.1002/admt.202470025
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