dr. E. Groot Jebbink (Erik)

I studied Technical medicine between 2006 and 2013 at the University of Twente. My graduation project focused on the interaction between stents and blood flow in case of stenotic vascular pathologies. This topic has interested me ever since and I obtained my PhD on this topic within the Physics of Fluids group (University of Twente) in 2017, under the supervision of prof. dr. Michel Reijnen and prof. dr. Michel Versluis¹. My PhD work incorporated both in vitro and in vivo flow visualization, for which I spent time in the Labs of PoF and at the department of Vascular Surgery, Rijnstate Hospital Arnhem. My PhD was setup as a six year project with a 50/50 balance between research and education, I’m involved in several courses within the Technical Medicine program.

During my Postdoc period I expanded my PhD work into a new research line, within the multi-modality medical imaging (M3i) group. In 2019 I was appointed as an Assistant Professor at the M3i group. In this role I’m continuing my work on investigating the interaction of blood flow and stents in relation to the durability of stents to maximize the outcome for patients. My work has a clear translational and applied focus, therefore I have an active secondment at the department of vascular surgery at the Rijnstate hospital.

To visualize and quantify blood flow I apply (and develop) several tools. In vitro we make use of laser particle image velocimetry techniques, realistic flow phantoms and flow circuits to simulate parts of human circulatory system². In vivo we focus on the application of high frame-rate contrast enhanced ultrasound techniques³. Based on these techniques there are several project in which I’m involved:

Stichting Lijf en Leven project, focusing on the relation between blood flow and disease progression in case of aortoiliac peripheral arterial disease. Funded by the stichting Lijf en Leven.
ADEAR project, focusing on quantifying the in vivo deformation of endografts and in vitro interaction with blood flow at the timescale of a single heartbeat or breath cycle. Funded by the Connecting Industries Call and Terumo Aortic
2ACP project, focusing on optimizing the visualization of polymers used for injection in case of active sac filling. The second goal of the project is to investigate the mechanical interaction between the stent graft and polymer. Funded by the TKI-LSH PPP call from Health Holland and TripleMed Bv.
Ultra-x-treme project, focusing on the development and application of 3D ultrasound based blood flow quantification aligned with biomechanical models for patient-specific characterization of cardiovascular status. Funded by NWO through the Perspectief program and several companies
Vortecs project, focusing at obtaining 2D in vivo blood flow quantification, both with and without the use of contrast agents. Funded by NWO through the OTP program, next to Philips and Medtronic.

1. Groot Jebbink, E. (2017). Aortoiliac stenting, how blood flow and stents interact. University of Twente. https://ris.utwente.nl/ws/portalfiles/portal/129917651/thesis_E_Groot_Jebbink.pdf

2.Groot Jebbink, E., Mathai, V., Boersen, J. T., Sun, C., Slump, C. H., Goverde, P. C., ... & Reijnen, M. M. (2017). Hemodynamic comparison of stent configurations used for aortoiliac occlusive disease. Journal of vascular surgery, 66(1), 251-260.

3. Engelhard, S., Voorneveld, J., Vos, H. J., Westenberg, J. J., Gijsen, F. J., Taimr, P., ... & Groot Jebbink, E. (2018). High-frame-rate contrast-enhanced US particle image velocimetry in the abdominal aorta: first human results. Radiology, 289(1), 119-125.

Medicine & Life Sciences

# Abdominal Aortic Aneurysm
# Aneurysm
# In Vitro Techniques
# Renal Artery
# Rheology
# Stents
# Tomography

Physics & Astronomy

# Particle Image Velocimetry

Faculty of Science and Technology (TNW), Multi-Modality Medical Imaging (M3I)

Simmering, J. A. (2023). Endovascular Repair of the Aorta: Stentgraft Deformation Matters. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036555791

Taneva, G. T. , Mirgolbabaee, H. , Jebbink, E. G. , Reijnen, M. M. P. J., & Donas, K. P. (2023). Systematic Review of the Current In Vitro Experience of the Endovascular Treatment of Juxtarenal Abdominal Aortic Aneurysms by Fenestrated and Parallel Endografting. Journal of Endovascular Therapy, 30(1), 8-17. https://doi.org/10.1177/15266028221075242

Halfwerk, F. R., Clare, C. , Groot Jebbink, E. , & Groenier, M. (2022). Selected Abstracts from the 27th Annual Meeting of the Society in Europe for Simulation Applied to Medicine: Development and evaluation of a graduate surgical skills curriculum: How to make medical simulation data Findable, Accessible, Interoperable and Reusable. Advances in Simulation, 7(Suppl 1), 7-8. [0009]. https://doi.org/10.1186/s41077-022-00211-6

Ghanbarzadeh-Dagheyan, A. , Jebbink, E. G. , Reijnen, M. , & Versluis, M. (2022). Skewedness as a Signature of Dean Flow Measured by Echo-PIV. In Proceedings of IEEE International Ultrasonics Symposium 2022 https://doi.org/10.1109/IUS54386.2022.9958480

van Helvert, M. , Engelhard, S., Voorneveld, J., van der Vee, M., Bosch, J. G. , Versluis, M. , Groot Jebbink, E. , & Reijnen, M. M. P. J. (2022). High-frame-rate contrast-enhanced ultrasound particle image velocimetry in patients with a stented superficial femoral artery: a feasibility study. European radiology experimental, 6(1), [32]. https://doi.org/10.1186/s41747-022-00278-w

Halfwerk, F. R., Clare, C. , Groot Jebbink, E. , & Groenier, M. (2022). Development and evaluation of a graduate surgical skills curriculum: How to make medical simulation data Findable, Accessible, Interoperable and Reusable. Abstract from 27th Annual Meeting of Society for Simulation in Europe 2022, Seville, Spain.

Halfwerk, F. R. , Groot Jebbink, E. , & Groenier, M. (2022). Proficient before practice: Graduate simulation-based surgical skills training increases confidence in technical skills. Abstract from 27th Annual Meeting of Society for Simulation in Europe 2022, Seville, Spain.

Engelhard, S. , van Helvert, M., Voorneveld, J., Bosch, J. G. , Lajoinie, G. , Jebbink, E. G. , Reijnen, M. M. P. J. , & Versluis, M. (2022). Blood Flow Quantification with High-Frame-Rate, Contrast-Enhanced Ultrasound Velocimetry in Stented Aortoiliac Arteries: In Vivo Feasibility. Ultrasound in medicine and biology, 48(8), 1518-1527. https://doi.org/10.1016/j.ultrasmedbio.2022.03.016

Velde, L. V. D. , Jebbink, E. G. , Hagmeijer, R. , Versluis, M. , & Reijnen, M. M. P. J. (2022). Computational Fluid Dynamics for the Prediction of Endograft Thrombosis in the Superficial Femoral Artery. Journal of Endovascular Therapy. https://doi.org/10.1177/15266028221091890

van de Velde, L. , Groot Jebbink, E., Zambrano, B. A. , Versluis, M., Tessarek, J. , & Reijnen, M. M. P. J. (2022). The Supera Interwoven Nitinol Stent as a Flow Diverting Device in Popliteal Aneurysms. CardioVascular and Interventional Radiology, 45, 858-866. https://doi.org/10.1007/s00270-022-03118-x

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e.grootjebbink@utwente.nl

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University of Twente
Faculty of Science and Technology
Technohal (building no. 18), room 2381
Hallenweg 5
7522NH Enschede
The Netherlands

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University of Twente
Faculty of Science and Technology
Technohal 2381
P.O. Box 217
7500 AE Enschede
The Netherlands

Faculty of Science and Technology (TNW), Multi-Modality Medical Imaging (M3I)

University of Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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Technical Physician | Assistant Professor

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