Fields of interest
Rehabilitation robotics for the lower extremities, human-machine interaction, dynamic balance control, locomotor adaptation, neuroplasticity

Edwin van Asseldonk has a master in Human Movement Sciences from the Free University in Amsterdam and a PhD in Biomechanical Engineering from the University of Twente. He currently holds the position of associate professor at the University of Twente. His research aims to improve the walking ability of patients with neurological diseases like stroke or spinal cord injury by using rehabilitation robotics (therapeutic and assistive) and/or non-invasive direct current stimulation. His current research concentrates on developing balance control strategies for wearable exoskeletons and investigating the human-machine interaction. He is principal investigator on different national (funded by STW and ZonMW) projects and co-principal investigator on international projects (funded by EU) on rehabilitation robotics and non-invasive stimulation. He has published over 100 papers and conference proceedings in the area of balance control during stance and walking, motor adaptation, lower limb rehabilitation robotics and non-invasive brain stimulation.


  • Medicine and Dentistry

    • Walking
    • Gait
    • Exoskeleton
    • Ankle
    • Pelvis
    • Joint
    • Foot
  • Nursing and Health Professions

    • Robotics



Robust and versatile control of lower limb exoskeletons. University of Twente. Rampeltshammer, W. F. the role of intrinsic and reflexive contributions to ankle joint hyper-resistance treated with botulinum toxin-AJournal of neuroengineering and rehabilitation, 20(1), Article 19. van 't Veld, R. C., Flux, E., van Oorschot, W., Schouten, A. C., van der Krogt, M. M., van der Kooij, H., Vos-van der Hulst, M., Keijsers, N. L. W. & van Asseldonk, E. H. F. on ankle-foot technology for improving gait performance of children with Cerebral Palsy in daily-life: requirements, needs and wishesJournal of neuroengineering and rehabilitation, 20, Article 44. Bayon, C., van Hoorn, M., Barrientos, A., Rocon, E., Trost, J. P. & van Asseldonk, E. H. F. of Two Design Principles of Unpowered Ankle-Foot Orthoses for Supporting Push-Off: A Case StudyIn 2023 International Conference on Rehabilitation Robotics (ICORR) (pp. 1-6). IEEE. Bayon, C., Van Crey, N., Rocon, E., Rouse, E. & van Asseldonk, E. Balance Control of a Lower-Limb Exoskeleton During StanceIn 2023 International Conference on Rehabilitation Robotics (ICORR) (pp. 1-6). IEEE. Vallinas, A., Keemink, A., Bayon, C., van Asseldonk, E. & van der Kooij, H. Based foot Placement in Stumble RecoveryIn 2023 International Conference on Rehabilitation Robotics, ICORR 2023. IEEE. Eveld, M., Van Der Kooij, H., King, S., Goldfarb, M., Zelik, K. & Van Asseldonk, E. of perturbation timing on recovering whole-body angular momentum during very slow walkingHuman movement science, 91, Article 103138. van Mierlo, M., Abma, M., Vlutters, M., van Asseldonk, E. H. F. & van der Kooij, H. and Comparison of SEA Torque Controllers in a Unified FrameworkActuators, 12(8), Article 303. Rampeltshammer, W. F., Keemink, A., Sytsma, M., Asseldonk, E. v. & van der Kooij, H. on mechanical designs for assistive ankle-foot orthosesFrontiers in bioengineering and biotechnology, 11, Article 1188685. Lora-Millán, J., Nabipour, M., van Asseldonk, E. H. F. & Bayon, C. walking balance using a bio-inspired exoskeleton controllerJournal of neuroengineering and rehabilitation, 20(1), Article 82. Afschrift, M., van Asseldonk, E., van Mierlo, M., Bayón, C., Keemink, A., D’Hondt, L., van der Kooij, H. & De Groote, F. linear and angular momentum during walking. University of Twente. van Mierlo, M. balance perturbations during very slow walking: Strategies for recovering linear and angular momentumJournal of biomechanics, 152, Article 111580. van Mierlo, M., Vlutters, M., van Asseldonk, E. H. F. & van der Kooij, H., Design of an Exergame for Balance Recovery of Stroke Patients for a Home EnvironmentIn CHI 2023 - Extended Abstracts of the 2023 CHI Conference on Human Factors in Computing Systems, Article 499. Association for Computing Machinery. Ruiz-Rodriguez, A., Hermens, H. & Van Asseldonk, E. perturbations in various directions while standing in staggered stance elicit concurrent responses in both the sagittal and frontal planePLoS ONE, 18(4), Article e0272245. van Mierlo, M., Ormiston, J., Vlutters, M., van Asseldonk, E. H. F. & van der Kooij, H.

Other contributions

Supervised PhD thesis:

  1. Robot aided gait training and assessment: development of support strategies and assessment methods for LOPES Bram Koopman (10 December 2014).
  2. Design of a robot-assisted gait trainer: LOPES II. Johannes Hendricus Meuleman (13 November 2015).
  3. Foot Placement in balance recovery - complex humans vs simple model (sumacum laude). Mark Vlutters (13 December 2017)
  4. Trans-Spinal Direct Current Stimulation for the Modulation of the Lumbar Spinal Motor Networks. Alexander Kuck (24 January 2018).
  5. Motor sequence learning in older adults. Jonathan S. Barnhoorn (18 April, 2018)
  6. Haptic human-human interaction: motor learning & haptic communication. Niek Beckers (12 July 2019)
  7. Towards postural balance control of exoskeletons. Amber R. Emmens (8 May 2020)
  8. Towards personalized robot-assisted gait training. Simone S. Fricke (10 July 2020)
  9. Integrated spasticity assessment and treatment using disentangled joint resistance. Ronald van 't Veld (25 May 2022)

Research profiles

I am coordinator and lectures of the master courses Human Movement Control and Identitication of Human Physiological systems. Besides I supervise bachelor and master assignments of mainly the BME and ME program.  

Besides I am track coordinator of the Biorobotics specialisation of the Biomedical Engineering Master program.

Affiliated study programs

Courses academic year 2023/2024

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2022/2023

Current projects

HEROES: Home-based ExeRgaming fOr Enhancing resistance to falls after Stroke

This project aims to develop the HEROES system, for home-based exergaming (exercise + gaming) to enhance resistance to falls in community-dwelling stroke survivors.

BenchBalance: A device to apply well defined perturbations for benchmarking balance capabilities of wearable robots

This project aims to develop a low-cost perturbation tool capable of measuring well-defined external perturbations manually provided by an experimenter to subjects wearing an exoskeleton. This tool will be used to benchmark balance capabilities of wearable robots.

Balance control in challenging conditions

This project is part of the TTW program Wearable Robotics. The aim of this project is to develop human-inspired control algorithms for exoskeletons to ensure balance is maintained in different challenging conditions during standing and walking.

Exo-aid for Spinal Cord Injury subjects

This project is part of the TTW program Wearable Robotics. The aim of this project is to develop a user-interface, control algorithms, and sensory substitution methods that will allow for fast, stable, and versatile locomotion of people with an SCI walking with an Exo-Aid.

Reflexioning: training the modulation of reflex activity in subjects with Spinal Cord Injury and Cerebral Palsy

This project is part of the STW program NeuroCIMT. The aim of the project is to develop a non-invasive integrated assessment and treatment approach to reduce spasticity and improve walking ability in patients with spinal cord injury and cerebral palsy.


Veni Cristina Bayón Calderón

With inGAIT project, we aim to go beyond the conventional methods of CP rehabilitation by investigating the expansion of novel technologies to daily-life. Our motivation for this research is to improve the quality of life of children with CP and similar motor disorders.

Finished projects

Wearable Robots for Augmentation, Assistance or Substitution of Human Motor Functions (COST Action)

The main aim of this COST action is to Integrate diverse expertise and develop trans-domain competences that are essential to the development of a new generation of Wearable Robots (WRs). The working group on Fondational sciences focusses on identifying the key open issues in human-machine interaction.


Follow up project of LOPES. Development of robotic gait trainer suited for a clinical setting and which will be evaluated within the project period in a clinical trial with acute stroke survivors and spinal cord injury subjects.

Mindwalker (EU)

Priming the brain for robotic training (ZonMW VENI)

This project aims to enhance cortical plasticity and functional recovery in stroke survivors by the integration of cortical brain stimulation in robotic gait training

ReLOAD: Motor skill Learning in Older ADults: neurocognitive correlates, individual differences, and interventions to enable healthy aging (NWO)

This project aims to understand the effect of age on learning new motor skills and to assess how non-invasive brain stimulation (tDCS) can increase the capacitiy of older individuals to learn.

ARTS Efficacy of Assist-As-Needed (AAN) Robotic gait Training in sub-acute Stroke survivors (ZonMW)

In this project a radomized clinical trial is performed to compare gait training in LOPESII using an Assist-As-Needed approach to conventional gait training in a population of sub-acute stroke survivors.

Evryon (EU)

BALANCE Balance Augmentation in Locomotion, through Anticipative, Natural and Cooperative control of Exoskeletons (EU)

This project aims to realize an exoskeletal robot that improves the balance performance of humans, targeted at users facing balance-challenging conditions or suffering from a lack of ability to walk or maintain balance during walking.

AWARD: Assessment during Walking using A Robotic Device (STW)

This project aims to improve the outcome of robot-aided gait training by tailoring the robotic support to the individual patient’s impairments. We will develop and evaluate protocols and algorithms to quantify the primary motor impairments while subjects are walking.

NeurAS: NEURoControl- Assessment and Stimulation (ZonMW)

This project aims to improve the outcome of gait training in spinal cord injury patients through development of a novel non-invasive stimulation paradigm that in combination with robotic support promotes neuroplasticity.

Symbitron (EU)

In this project we will develop personalzed wearable exoskeletons for SCI patients. This exoskeleton is controlled with biologically inspired controllers

Our work on the development and use of the robotic gait trainer LOPES and the wearable exoskeleton Mindwalker has attracted considerable national and international attention in the popular media.

In the press



RTV oost nieuws, May 6, 2014: “Roessingh en Universiteit Twente ontwikkelen revalidatierobot Lopes”.

Omroep Gelderland nieuws, May 14, 2014: “Sint Maartenskliniek test nieuwe looprobot”.

BBC news, Sep 25, 2011: “Robo legs help stroke victim to walk”.

SBS6 Hart van Nederland, Oct 3, 2011: “Robot is doorbraak in revalidatie”.

Reuters, Jan 12, 2011: “Robot legs help stroke survivors to walk again”.

NTR-VPRO program Labyrinth, Apr 5, 2011: “De machinemens”.

Vara’s Nieuwslicht, Nov 19, 2008: “Robot benen helpen mensen sneller op de been


BNR eyeopeners, May 12, 2014: “Een robot die je leert lopen”.

Newspapers, websites & magazines

LOPES II in De Ingenieur, Nov 2014: Weer leren lopen: robot ontlast fysiotherapeut

LOPES II in Bits & Chips, Sep 19, 2014: “Looprobot zet stap naar commerciële versie

LOPES II in De Gelderlander, May 9, 2014, : “Robot leert patiënten in kliniek weer lopen

LOPES II op RTLnieuws site, May 8, 2014: Looprobot Lopes II is een grote stap vooruit

LOPES II op, May 6, 2014: “Klinieken zetten nieuwe looprobot in voor revalidatie patiënten

Lopes in The Consultant Journal, Oct 2011: “Dutch Rehabilitation robot helps patients to learn how to walk again



Euronews, Sep 30, 2013: “Exoskeletons on the March”.

Newspapers, websites & magazines

Mindwalker in de New Scientist, Jun 7, 2014: “Exoskelet laat verlamde mensen lopen

Mindwalker in de Ingenieur, Sep 6, 2013: “Exoskelet dat het wel doet”.
Mindwalker in Horizon the EU Research and Innovation Magazine, May 30, 2014: “Walking again with an exoskeleton

News on!/2017/11/342217/major-funding-for-wearable-robotics!/2017/10/240526/edwin-van-asseldonk-in-dutch-tv-programme-klaas-kan-alles!/2015/6/221734/the-netherlands-and-the-united-states-strengthen-collaborative-research-into-neuro-rehabilitation


University of Twente

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