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dr. E. Mos - Oppersma (Eline)

Assistant Professor

About Me

Studying Technical Medicine at the University of Twente, I already focused on respiratory physiology with a graduation project on the pulmonary function department of the Medisch Spectrum Twente in Enschede.
From 2011 I started to work at the University of Twente as lecturer in the Technical Medicine program, and as a PhD student. My PhD project focused on monitoring and regulation of supported breathing in Intensive Care, in collaboration with the Intensive Care of the Radboud hospital in Nijmegen.
After obtaining my PhD in 2018, I went to the United States for a postdoc at the Massachusetts General Hospital in Boston, where I worked on an algorithm for automatic detection of self-similarity and prediction of residual central events during continuous positive airway pressure. 

From 2019, I was appointed as an assistant professor in the Cardiovascular and Respiratory Physiology group. My research focuses on regulation of breathing and noninvasive methods to assess lung mechanics and activity of respiratory muscles. An important tool is electromyography (EMG) of the respiratory muscles, including the diaphragm. Although noninvasive measurement of respiratory EMG, with surface electrodes attached on the skin, challenges data analysis due to movement artefacts and interference of activity from other muscles, it has the potential to be of high clinical value in daily monitoring of patients on the intensive care or during home mechanical ventilation. Other tools include pressure and flow monitoring and interventions in patients receiving mechanical ventilation. In all monitoring tools, I aim to study adequate acquisition, advanced analysis and clinical adaptation and interpretation of the data. All is focused at gaining more insight in the respiratory pump physiology, leading to better adaptation and weaning of patients from mechanical ventilation.

Expertise

Medicine & Life Sciences
Central Sleep Apnea
Chronic Obstructive Pulmonary Disease
Continuous Positive Airway Pressure
Diaphragm
Interactive Ventilatory Support
Mechanical Ventilators
Noninvasive Ventilation
Ventilation

Publications

Recent
Oppersma, E., Geraats, S., Heikens, N. H., Welleweerd, A., Woerts, C. A. , Fresiello, L., Meuwese, C. L. , & Donker, D. W. (2022). Finite Element Modeling of Pulmonary Mechanics in Severe ARDS: Explaining the Inclination Angle? American journal of respiratory and critical care medicine. https://doi.org/10.1164/rccm.202205-0931LE
Oppersma, E., Ganglberger, W., Sun, H., Thomas, R., & Westover, M. (2021). 475 Automatic detection of self-similarity and prediction of CPAP failure. Sleep, 44(S2), A187-A187. https://doi.org/10.1093/sleep/zsab072.474
Oppersma, E., Ganglberger, W., Sun, H., Thomas, R. J., & Westover, M. B. (2021). Automatic detection of self-similarity and prediction of CPAP failure. Poster session presented at 35th Annual Meeting of the Associated Professional Sleep Societies, SLEEP 2021.
Jonkman, A. H., Frenzel, T., McCaughey, E. J., McLachlan, A. J., Boswell-Ruys, C. L., Collins, D. W., Gandevia, S. C., Girbes, A. R. J., Hoiting, O., Kox, M., Peters, M. , Oppersma, E., Pickkers, P., Roesthuis, L. H., Schouten, J., Shi, Z. H. , Veltink, P. H., de Vries, H. J., Shannon Weickert, C., ... Heunks, L. M. A. (2020). Breath-synchronized electrical stimulation of the expiratory muscles in mechanically ventilated patients: a randomized controlled feasibility study and pooled analysis. Critical care, 24(1), [628]. https://doi.org/10.1186/s13054-020-03352-0
Oppersma, E., Doorduin, J., Gooskens, P. J., Roesthuis, L. H., van der Heijden, E. H. F. M., van der Hoeven, J. G. , Veltink, P. H., & Heunks, L. M. A. (2019). Glottic patency during noninvasive ventilation in patients with chronic obstructive pulmonary disease. Respiratory Physiology and Neurobiology, 259, 53-57. https://doi.org/10.1016/j.resp.2018.07.006

UT Research Information System

Courses Academic Year  2022/2023

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
 

Courses Academic Year  2021/2022

Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Technohal (building no. 18), room 3181
Hallenweg 5
7522NH  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Technohal  3181
P.O. Box 217
7500 AE Enschede
The Netherlands