Technohal

dr. E. Mos - Oppersma (Eline)

Assistant Professor
TNW-BIS-CRPH
Technohal 3181
e.mos-oppersma@utwente.nl
+31534894496
Business card

Studying Technical Medicine at the University of Twente, I already focused on respiratory physiology with a graduation project on the pulmonary function department of the Medisch Spectrum Twente in Enschede.
From 2011 I started to work at the University of Twente as lecturer in the Technical Medicine program, and as a PhD student. My PhD project focused on monitoring and regulation of supported breathing in Intensive Care, in collaboration with the Intensive Care of the Radboud hospital in Nijmegen.
After obtaining my PhD in 2018, I went to the United States for a postdoc at the Massachusetts General Hospital in Boston, where I worked on an algorithm for automatic detection of self-similarity and prediction of residual central events during continuous positive airway pressure. 

From 2019, I was appointed as an assistant professor in the Cardiovascular and Respiratory Physiology group. My research focuses on regulation of breathing and noninvasive methods to assess lung mechanics and activity of respiratory muscles. An important tool is electromyography (EMG) of the respiratory muscles, including the diaphragm. Although noninvasive measurement of respiratory EMG, with surface electrodes attached on the skin, challenges data analysis due to movement artefacts and interference of activity from other muscles, it has the potential to be of high clinical value in daily monitoring of patients on the intensive care or during home mechanical ventilation. Other tools include pressure and flow monitoring and interventions in patients receiving mechanical ventilation. In all monitoring tools, I aim to study adequate acquisition, advanced analysis and clinical adaptation and interpretation of the data. All is focused at gaining more insight in the respiratory pump physiology, leading to better adaptation and weaning of patients from mechanical ventilation.

Expertise

  • Medicine and Dentistry

    • Patient
    • Diaphragm
    • Noninvasive Ventilation
    • Obstructive Sleep Apnea
    • Continuous Positive Airway Pressure
    • Breathing
    • Chronic Obstructive Pulmonary Disease
    • Systematic Review

Organisations

Publications

2026

Development of an automated assessment of ultrasound measured diaphragm thickness (2026)Computer methods and programs in biomedicine, 276. Article 109220. Koopman, A. A., Burger, J., Laarman, K., van der Steen, D., Blokpoel, R. G. T., Oppersma, E. & Kneyber, M. C. J.https://doi.org/10.1016/j.cmpb.2025.109220Computational physiological models for hemodynamic management in critical care: a systematic literature review focusing on model design, credibility and clinical readiness (2026)Computers in biology and medicine, 205. Article 111561 (E-pub ahead of print/First online). Mulder, M. P., Warnaar, R. S. P., Arendshorst-Ruuls, T. F., van Loon, L. M., Meuwese, C. L., Broomé, M., Oppersma, E., Donker, D. W. & Fresiello, L.https://doi.org/10.1016/j.compbiomed.2026.111561Corrigendum to: “Association between high loop gain sleep apnea detected by respiratory self-similarity and left ventricular remodeling” [Sleep Med 140 (2026) 108796] (2026)Sleep Medicine, 141. Article 108821 (E-pub ahead of print/First online). Wu, W., Zhong, S., Oppersma, E., Ganglberger, W., Luo, F., Ni, Y. & Thomas, R. J.https://doi.org/10.1016/j.sleep.2026.108821Computational physiological modeling for lung-specific ventilation and perfusion management in ex vivo lung perfusion (2026)Frontiers in Physiology, 16. Article 1724724. Imholz, D., Braithwaite, S. A., Blankman, P., Oppersma, E., de Jongh, F. H. C., de Heer, L. M., Luijk, B., Buhre, W. F. F. A., Donker, D. W. & van Loon, L. M.https://doi.org/10.3389/fphys.2025.1724724Association between high loop gain sleep apnea detected by respiratory self-similarity and left ventricular remodeling (2026)Sleep, 140. Article 108796 (E-pub ahead of print/First online). Wu, W., Zhong, S., Oppersma, E., Ganglberger, W., Luo, F., Ni, Y. & Thomas, R. J.https://doi.org/10.1016/j.sleep.2026.108796Continuous and noninvasive respiratory effort monitoring:: A narrative review of emerging techniques (2026)Journal of Intensive Care, 14(1). Article 9 (E-pub ahead of print/First online). Grasshoff, J., Warnaar, R. S. P., Donker, D. W., Rostalski, P. & Oppersma, E.https://doi.org/10.1186/s40560-026-00852-z

2025

Acquisition of respiratory surface EMG: A systematic literature review of electrode configurations and methodological reporting (2025)Critical care, 29(1). Article 476. Warnaar, R. S. P., Francovich, J. E., van Baaren, L., Donker, D. W., Jonkman, A. H. & Oppersma, E.https://doi.org/10.1186/s13054-025-05696-xAdvanced serial analysis of the diaphragm surface EMG: insights into the effect of pressure support on the neuro-ventilatory response during the ICU stay (2025)Critical care, 29(1). Article 258. Warnaar, R. S. P., Cornet, A. D., Beishuizen, A., Donker, D. W. & Oppersma, E.https://doi.org/10.1186/s13054-025-05424-5ReSurfEMG: A Python Package for Comprehensive Analysis of Respiratory Surface EMG (2025)Sensors (Switzerland), 25(20). Article 6465. Warnaar, R. S. P., Moore, C. M., Baccinelli, W., Soleimani, F., Donker, D. W. & Oppersma, E.https://doi.org/10.3390/s25206465Unraveling sleep apnea dynamics: quantifying loop gain using dynamical modeling of ventilatory control (2025)Sleep, 49(2). Article zsaf213. Nassi, T., Amidi, Y., Oppersma, E., Donker, D. W., Redeker, N. S., Westover, M. B. & Thomas, R. J.https://doi.org/10.1093/sleep/zsaf213

Research profiles

Address

University of Twente

Technohal (building no. 18), room 3181
Hallenweg 5
7522 NH Enschede
Netherlands

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