Technohal

dr. E. Mos - Oppersma (Eline)

Assistant Professor
TNW-BIS-CRPH
Technohal 3181
e.mos-oppersma@utwente.nl
+31534894496
Business card

Studying Technical Medicine at the University of Twente, I already focused on respiratory physiology with a graduation project on the pulmonary function department of the Medisch Spectrum Twente in Enschede.
From 2011 I started to work at the University of Twente as lecturer in the Technical Medicine program, and as a PhD student. My PhD project focused on monitoring and regulation of supported breathing in Intensive Care, in collaboration with the Intensive Care of the Radboud hospital in Nijmegen.
After obtaining my PhD in 2018, I went to the United States for a postdoc at the Massachusetts General Hospital in Boston, where I worked on an algorithm for automatic detection of self-similarity and prediction of residual central events during continuous positive airway pressure.Ā 

From 2019, I was appointed as an assistant professor in the Cardiovascular and Respiratory Physiology group. My research focuses on regulation of breathing and noninvasive methods to assess lung mechanics and activity of respiratory muscles. An important tool is electromyography (EMG) of the respiratory muscles, including the diaphragm. Although noninvasive measurement of respiratory EMG, with surface electrodes attached on the skin, challenges data analysis due to movement artefacts and interference of activity from other muscles, it has the potential to be of high clinical value in daily monitoring of patients on the intensive care or during home mechanical ventilation. Other tools include pressure and flow monitoring and interventions in patients receiving mechanical ventilation. In all monitoring tools, I aim to study adequate acquisition, advanced analysis and clinical adaptation and interpretation of the data. All is focused at gaining more insight in the respiratory pump physiology, leading to better adaptation and weaning of patients from mechanical ventilation.

Expertise

  • Medicine and Dentistry

    • Patient
    • Diaphragm
    • Noninvasive Ventilation
    • Continuous Positive Airway Pressure
    • Chronic Obstructive Pulmonary Disease
    • Breathing
    • Apnea
    • Pressure Support Ventilation

Organisations

Publications

2025

Acquisition of respiratory surface EMG: A systematic literature review of electrode configurations and methodological reporting (2025)Critical care, 29(1). Article 476. Warnaar, R. S. P., Francovich, J. E., van Baaren, L., Donker, D. W., Jonkman, A. H. & Oppersma, E.https://doi.org/10.1186/s13054-025-05696-xAdvanced serial analysis of the diaphragm surface EMG: insights into the effect of pressure support on the neuro-ventilatory response during the ICU stay (2025)Critical care, 29(1). Article 258. Warnaar, R. S. P., Cornet, A. D., Beishuizen, A., Donker, D. W. & Oppersma, E.https://doi.org/10.1186/s13054-025-05424-5ReSurfEMG: A Python Package for Comprehensive Analysis of Respiratory Surface EMG (2025)Sensors (Switzerland), 25(20). Article 6465. Warnaar, R. S. P., Moore, C. M., Baccinelli, W., Soleimani, F., Donker, D. W. & Oppersma, E.https://doi.org/10.3390/s25206465Unravelling Sleep Apnea Dynamics: Quantifying Loop Gain Using Dynamical Modelling of Ventilatory Control (2025)Sleep. Nassi, T.-E., Amidi, Y., Oppersma, E., Donker, D. W., Redeker, N. S., Westover, M. B. & Thomas, R. J.https://doi.org/10.1093/sleep/zsaf2130682 Recognition of High Loop Gain Respiration: Comparison of Self-Similarity Analysis and Clinician Interpretation (2025)Sleep, 48(Supplement 1), A297-A297. Russo, J., Abigayle, S., Anwar, A., Nassi, T.-E., Oppersma, E., Labarca, G., Westover, M. B. & Thomas, R.https://doi.org/10.1093/sleep/zsaf090.0682Diaphragm Pacing in Early Critical Illness? A Plea for a Super-Relaxed Approach (2025)American journal of respiratory and critical care medicine, 211(3), 316-318. Heunks, L., Donker, D. W., Oppersma, E., Ottenheijm, C. A. C. & Doorduin, J.https://doi.org/10.1164/rccm.202408-1642VPMorphological Prediction of Continuous Positive Airway Pressureā€“associated Acute Respiratory Instability (2025)Annals of the American Thoracic Society, 22(1), 138-149. Nassi, T. E., Oppersma, E., Labarca, G., Donker, D. W., Westover, M. B. & Thomas, R. J.https://doi.org/10.1513/AnnalsATS.202311-979OC

2024

Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels (2024)Critical care, 28(1). Article 195. Warnaar, R. S. P., Cornet, A. D., Beishuizen, A., Moore, C. M., Donker, D. W. & Oppersma, E.https://doi.org/10.1186/s13054-024-04978-0Deventilation Syndrome in Patients with Chronic Obstructive Pulmonary Disease Using Nocturnal Noninvasive Ventilation: What Are the Underlying Mechanisms? (2024)Respiration; international review of thoracic diseases, 103(12), 723-732. Elshof, J., Oppersma, E., Wisse, J. J., Bladder, G., Meijer, P. M., Torres, A., Wijkstra, P. J. & Duiverman, M. L.https://doi.org/10.1159/000540780Additional file 2 of Advanced waveform analysis of diaphragm surface EMG allows for continuous non-invasive assessment of respiratory effort in critically ill patients at different PEEP levels (2024)[Dataset Types › Dataset]. figshare. Warnaar, R. S. P., Cornet, A. D., Beishuizen, A., Moore, C. M., Donker, D. W. & Mos-Oppersma, E.https://doi.org/10.6084/m9.figshare.26731483

Research profiles

Address

University of Twente

Technohal (building no. 18), room 3181
Hallenweg 5
7522 NH Enschede
Netherlands

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