Frank Simonis studied Biomedical Engineering at the Eindhoven University of Technology (TU/e). He graduated from the TU/e in 2011 on research in the group of professor Nicolay focused on a novel method to obtain T2 maps of the mouse heart. He started his PhD at the University Medical Centre of Utrecht under professor Jan Lagendijk with supervision of dr. Nico van den Berg. In his PhD project the body's physiological response to local RF heating caused by MR measurements was investigated. The capacity of the body to regulate temperature at a local scale (e.g. by elevation of local blood flow) is largely unknown and was a main topic of his research. Next to that, he did research on improving the estimation of the arterial input function in dynamic contrast enhanced MRI.

He currently is assistant professor in the Magnetic Detection and Imaging group where he mainly teaches courses covering MRI in the Technical Medicine and Biomedical Engineering programs. His research within the group focusses on new applications of low-field MRI (≤1.5T).

Expertise

  • Medicine and Dentistry

    • Magnetic Resonance Imaging
    • Pelvic Organ Prolapse
    • Diagnosis
    • Position
    • Patient
    • Pelvis
    • Standing
  • Nursing and Health Professions

    • Nuclear Magnetic Resonance Imaging

Organisations

Publications

2026

Differences in pessary support between successful and unsuccessful fit: an analysis in upright position (2026)American Journal of Obstetrics & Gynecology, 234(1), 149-157. van der Steen, A., De Alba Alvarez, I., Simonis, F. F. J., Grob, A. T. M. & van den Noort, F.https://doi.org/10.1016/j.ajog.2025.08.013

2025

Pelvic organ prolapse and pressary treatment: Insights with upright MRI (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. van der Steen, A.https://doi.org/10.3990/1.9789036568807Simulating workload reduction with an AI-based prostate cancer detection pathway using a prediction uncertainty metric (2025)European radiology, 35(12), 7821-7831. Fransen, S. J., Bosma, J. S., van Lohuizen, Q., Roest, C., Simonis, F. F. J., Kwee, T. C., Yakar, D. & Huisman, H.https://doi.org/10.1007/s00330-025-11727-6The scientific evidence of commercial AI products for MRI acceleration: a systematic review (2025)European radiology, 35(8), 4736-4746. Fransen, S. J., Roest, C., Simonis, F. F. J., Yakar, D. & Kwee, T. C.https://doi.org/10.1007/s00330-025-11423-5Pelvic Organ Prolapse Quantification After Pessary Removal: The Use of Upright MRI in POP Research (2025)International Urogynecology Journal, 36(7), 1541-1544. van der Steen, A., Simonis, F. F. J. & Grob, A. T. M.https://doi.org/10.1007/s00192-025-06182-2The influence of sacrocolporectopexy on pelvic anatomy assessed in an upright position using MRI (2025)Colorectal disease, 27(5). Article e70114. Kortman, M. C. P., Vanstiphout, J. W. P., Alhafidh, A., Simonis, F. F. J. & Grob, A. T. M.https://doi.org/10.1111/codi.70114Patient perspectives on the use of artificial intelligence in prostate cancer diagnosis on MRI (2025)European radiology, 35(2), 769–775. Fransen, S. J., Kwee, T. C., Rouw, D., Roest, C., van Lohuizen, Q. Y., Simonis, F. F. J., van Leeuwen, P. J., Heijmink, S., Ongena, Y. P., Haan, M. & Yakar, D.https://doi.org/10.1007/s00330-024-11012-y

2024

Analysing the support mechanisms of the vaginal ring pessary on supine and upright MRI (2024)Scientific reports, 14(1). Article 30951. van den Noort, F., de Alba Alvarez, I., van der Steen, A., Smelt, A. D., Simonis, F. F. J. & Grob, A. T. M.https://doi.org/10.1038/s41598-024-81985-9Assessing deep learning reconstruction for faster prostate MRI: visual vs. diagnostic performance metrics (2024)European radiology, 34, 7364-7372. van Lohuizen, Q., Roest, C., Simonis, F. F. J., Fransen, S. J., Kwee, T. C., Yakar, D. & Huisman, H.https://doi.org/10.1007/s00330-024-10771-yRecent Developments in Speeding up Prostate MRI (2024)Journal of magnetic resonance imaging, 60(3), 813-826. Mir, N., Fransen, S. J., Wolterink, J. M., Fütterer, J. J. & Simonis, F. F. J.https://doi.org/10.1002/jmri.29108

Research profiles

Address

University of Twente

Technohal (building no. 18), room 2184
Hallenweg 5
7522 NH Enschede
Netherlands

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