dr.ir. F.F.J. Simonis (Frank)

Frank Simonis studied Biomedical Engineering at the Eindhoven University of Technology (TU/e). He graduated from the TU/e in 2011 on research in the group of professor Nicolay focused on a novel method to obtain T₂ maps of the mouse heart. He started his PhD at the University Medical Centre of Utrecht under professor Jan Lagendijk with supervision of dr. Nico van den Berg. In his PhD project the body's physiological response to local RF heating caused by MR measurements was investigated. The capacity of the body to regulate temperature at a local scale (e.g. by elevation of local blood flow) is largely unknown and was a main topic of his research. Next to that, he did research on improving the estimation of the arterial input function in dynamic contrast enhanced MRI.

He currently is assistant professor in the Magnetic Detection and Imaging group where he mainly teaches courses covering MRI in the Technical Medicine and Biomedical Engineering programs. His research within the group focusses on new applications of low-field MRI (≤1.5T).

Medicine & Life Sciences

# Individual Biological Variation
# Magnetic Fields
# Magnetic Resonance Imaging
# Pelvic Organ Prolapse
# Prostatic Neoplasms
# Temperature
# Thermometry

Engineering & Materials Science

# Magnetic Resonance Imaging

Faculty of Science and Technology (TNW), Magnetic Detection and Imaging (MD&I)

van der Steen, A. , Morsinkhof, L. M., Chen, L., de Vries, M. , Simonis, F. F. J. , & Grob, A. T. M. (2023). Assessment of daily variation in pelvic anatomy in women with and without pelvic organ prolapse. International Urogynecology Journal. https://doi.org/10.1007/s00192-023-05550-0

Rodriguez, R. D., Huizing, E., Ünlü, Ç. , Simonis, F. F. J., Bokkers, R. P. H., Vries, J-P. P. M. D. , Schuurmann, R. C. L., Nakladal, D., Buikema, H., Hillebrands, J-L., & Leuvenink, H. G. D. (2023). Validation of an ex vivo Flow Model Including Magnetic Resonance Imaging to Study the Effects of Endovascular Treatments on the Arterial Wall. Journal of vascular research, 60, 1-11. https://doi.org/10.1159/000529115

Kamphuis, M. E. , Kuipers, H. , Liefers, H. R., van Es, J. , Simonis, F. F. J. , Greuter, M. J. W. , Slump, C. H. , & Slart, R. H. J. A. (2022). A Multimodality Myocardial Perfusion Phantom: Initial Quantitative Imaging Results. Bioengineering, 9(9), [436]. https://doi.org/10.3390/bioengineering9090436

Morsinkhof, L. M., Schulten, M. K., DeLancey, J. O. L. , Simonis, F. F. J. , & Grob, A. T. M. (2022). Pelvic inclination correction system for magnetic resonance imaging analysis of pelvic organ prolapse in upright position. International Urogynecology Journal, 33, 2801-2807. https://doi.org/10.1007/s00192-022-05289-0

van Zandwijk, J. K., Kuijer, K. M., Stassen, C. M. , ten Haken, B. , & Simonis, F. F. J. (2022). Internal Jugular Vein Geometry Under Multiple Inclination Angles with 3D Low-Field MRI in Healthy Volunteers. Journal of magnetic resonance imaging, 56(5), 1302-1308. https://doi.org/10.1002/jmri.28182

Zee, J. M. V. D., Fitski, M. , Simonis, F. F. J., Ven, C. P. V. D., Klijn, A. J., Wijnen, M. H. W. A., & Steeg, A. F. W. V. D. (2022). Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients. Current Oncology, 29(2), 777-784. https://doi.org/10.3390/curroncol29020066

Christenhusz, A. , Pouw, J. J. , Simonis, F. F. J., Douek, M., Ahmed, M., Klaase, J. M., Dassen, A. E., Klazen, C. A. H., van der Schaaf, M. C. , ten Haken, B. , & Alic, L. (2022). Breast MRI in patients after breast conserving surgery with sentinel node procedure using a superparamagnetic tracer. European radiology experimental, 6(1), [3]. https://doi.org/10.1186/s41747-021-00257-7

Zandwijk, J. K. V. , Simonis, F. F. J. , Heslinga, F. G., Hofmeijer, E. I. S. , Geelkerken, R. H. , Haken, B. T., & Vegh, V. (Ed.) (2021). Comparing the signal enhancement of a gadolinium based and an iron-oxide based contrast agent in low-field MRI. PLoS ONE, 16(8), [e0256252]. https://doi.org/10.1371/journal.pone.0256252

Klawer, E. M. E., van Houdt, P. J. , Simonis, F. F. J. , van den Berg, C. A. T., Pos, F. J., Heijmink, S. W. T. P. J., Isebaert, S., Haustermans, K., & van der Heide, U. A. (2021). Erratum to: Improved repeatability of dynamic contrast-enhanced MRI using the complex MRI signal to derive arterial input functions: a test-retest study in prostate cancer patients (Magn Reson Med., (2019), 81, (3358–3369), 10.1002/mrm.27646). Magnetic resonance in medicine, 85(4), 2334-2336. https://doi.org/10.1002/mrm.28606

Schröder, F. F., Post, C. , Simonis, F. F. J., Wagenaar, F. B. M. , Huis in 't Veld, R. , & Verdonschot, N. (2020). Weight-bearing low field MRI after total knee arthroplasty in patient with and without complaints. Orthopaedic proceedings, 102-B(Suppl. 2), 99-99. https://online.boneandjoint.org.uk/doi/abs/10.1302/1358-992X.2020.2.099

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