Carré

prof.dr. F.R. Wurm (Frederik)

Full Professor
TNW-MM-SPC
Carré C4225
frederik.wurm@utwente.nl
Business card

Bibliography

Frederik R. Wurm (Prof. Dr. habil.) is the chair of the group “Sustainable Polymer Chemistry” (SPC) at the Universiteit Twente. The group is located in the Faculty of Science and Technology (TNW) in the Department of Molecules and Materials (M&M).

The SPC group designs polymeric materials with molecularly defined functions that lead to macroscopic properties. In recent years, especially biobased and biodegradable materials have been the focus of Frederik's research and building the main line of the SPC group. The expertise of the SPC group covers the synthesis of (bio)degradable polymers and nanocarriers for agricultural or biomedical applications but also other potential applications are currently studied - always with a focus on the molecular control of the properties of the final materials. Frederik's favorite biopolymer is lignin, which is also the core of several research projects, e.g. biodegradable nano- and microcarriers for agriculture. SPC also researches new synthetic strategies and applications of (bio)degradable polyphosphoesters (PPEs) or develops new protocols for well-defined polyamines by living polymerization of aziridines.

Frederik has published over 250 peer-reviewed papers and more than 19,000 citations (h-index: 66, November 2025).

 

Professional Experience

  • 2020-Present - Full professor and chair of the group “Sustainable Polymer Chemistry”, University of Twente, The Netherlands.
  • 2016 - Habilitation in Organic and Macromolecular Chemistry
  • 2012-2020 - Group leader of "Functional Polymers", Max Planck Institute for Polymer Research, Mainz, Germany.
  • 2013-2020 - "Junior Faculty" Max Planck Graduate Center
  • 2009-2011 - Postdoctoral Humboldt fellow EPFL, Switzerland.

 

Education

  • 2006-2009 - Dissertation at Johannes-Gutenberg-Universität, Mainz, Germany.
  • 2006 - "Diplomchemiker" Johannes Gutenberg-Universität, Mainz, Germany.
  • 2006-2001 - Studies of Chemistry Johannes Gutenberg-Universität, Mainz, Germany.

 

Awards & Honors

  • Polymer Chemistry Lectureship (2019)
  • European Polymer Journal Award 2018 – Materials Today (2019)
  • The “Dozentenpreis des Fonds der deutschen chemischen Industrie“ (2017)
  • Reimund Stadler Award of the German Chemical Society (2016)
  • Georg Manecke Preis der Gesellschaft Deutscher Chemiker (2014)
  • European Young Chemist Award of the European Chemical Society (2014)
  • Fellowship of the Chem. Ind. Fund. of the German Chemical Industry Association (2012 and 2013)
  • Rückkehrstipendium der Alexander-von-Humboldt-Stiftung (2011-2012)
  • DSM Science and Technology Award (3th place) (2009)
  • Feodor-Lynen Fellowship Alexander-von-Humboldt-Stiftung (2009-2011)
  • MAINZ PhD Award of the MAINZ Graduate School (2009)
  • DAAD Fellowship for International Exchange (2004-2005)

 

Organizational Responsibilities

  • 2024- present - Co-Founder of Phos4nova B.V.
  • 2022- present - Board of the Polymer Center Twente
  • 2022- present - Co-Founder of LigniLabs GmbH
  • 2022- present - Member of the Molecules Center Twente
  • 2020- present - Chair of the group "Sustainable Polymer Chemistry"
  • 2022- present - Editor for the European Polymer Journal
  • 2019- present - Advisory Board Member of Polymer Chemistry (RSC)
  • 2019-2022 - Editorial Board Member of Molecules (mdpi)
  • 2018-2019 - Executive Board Member of European Polymer Journal (Elsevier)
  • 2019- present - Advisory Board Member Schering Stiftung
  • 2012-2020 - Associated Member of the graduate school MAINZ (JGU, Mainz)
  • 2012-2020 - Associated Member of the Center for Innovative and Emerging Materials

Expertise

  • Chemistry

    • Polymer
    • Monomer
    • Copolymer
    • Synthesis (Chemical)
    • Group
    • Poly(ethylene Glycol)

  • Material Science

    • Polyphosphoester

  • Chemical Engineering

    • Polymerization

Organisations

Ancillary activities

  • Phos4Nova B.V.Scientific Advisor Phos4Nova
  • LigniLabs GmbHResearch Scientist

The “Sustainble Polymer Chemistry“ (SPC) group focusses on the development of novel synthesis strategies and polymeric materials to tackle different fundamental questions. The development of novel (bio)degradable materials, primarily based on phosphorus-containing polymers or biopolymers, such as starch or lignin, is a major research focus of the group. We combine modern organic and inorganic chemistry with precision polymer synthesis and colloidal formulations (miniemulsions, reactions at the interface, etc.) in order to produce smart materials for drug delivery, agriculture, adhesive technologies, flame retardants, and optics.

 

DNA as a blueprint for synthetic polyphosphoesters

Inspired by DNA, a natural polyphosphodiester, my group has especially driven the development of phosphorus-containing polymers, i.e. polyphosphoesters (PPEs). With the natural phosphate building block, biodegradable and biomimetic PPEs can be synthesized by different strategies. We take the bridging element from DNA to materials science as the installation of the phosphate group into the polymer main chain allows installing diverse chemical functionalities, which eventually control the properties of the materials such as chemical reactivity, folding, self-assembly, or interactions (functionality, responsibility, degradation, blood interactions). Such PPEs can be used in diverse applications and have an industrial interest (e.g. as surfactants or flame retardants). By a living ring-opening polymerization of cyclic phosphoesters, we were able to prepare libraries of functional PPEs, which degrade on demand and carry functional groups to allow drug attachment, surface-immobilization (Polym. Chem. 2018), adhesive (Biomacromolecules 2017) or anti-fouling properties (Nat. Nano. 2016), or flame-retardant properties (Polym. Chem. 2014). The class of PPEs has emerged in the last decade as a powerful polymer class for various applications and due to the versatility of its chemistry, it certainly will find applications in diverse areas of research and industry. We further developed a reliable protocol for the preparation of hydrophobic polyphosphoesters allowing the large-scale preparation of phosphate-based flame-retardants by engineering the chemical structure, we control the degradation during a fire event (collaboration project with BAM (Prof. Schartel)) (Polym. Chem. 2014, Angew. Chem. 2018).

In addition, smart polymers (with LCST and UCST) are accessible from PPEs (Polym. Chem. 2017). For example, amphiphilic polyphosphonate block copolymers carrying hydrogen-bonding motifs allowed us to assemble stimuli-responsive polymersomes, which can be reversibly opened and closed by a temperature trigger (J. Am. Chem. Soc. 2017). Such vesicles are a first step towards the development of compartmentalized reactors on the nano- or microscale that can release reagents. The overall hydrophilicity controls the interactions with blood proteins (Angew. Chem. 2018). Such materials have led to the unraveling of the “stealth effect” of nanocarriers which is an underlying principle for drug delivery (in collaboration with Universitätsmedizin Mainz) (Nat. Nano. 2016, Biomaterials 2015 & 2017). Nanocarriers, coated with hydrophilic PPEs exhibit a “stealth” effect, similar to the well-known poly(ethylene glycol), rendering them perfect biodegradable alternatives, especially for chronical diseases.

Plastics and Biodegradable Polymers


We live in a polymer age – our modern life is shaped by polymers every day. From food packaging to high-tech polymers in our laptops or cars, synthetic macromolecules surround us.

Research in the “SPC” Group is driven by the molecular design of (bio)degradable polymers – both fully synthetic or based on modified biopolymers.

We design biodegradable nanocarriers, i.e. nanoscopic packaging, of drugs, which we use together with the Uniclinics or the Biology department in Mainz for drug delivery – into cells for the treatment of human diseases, but also as targeted drug delivery inside of plants. The latter project especially targets the treatment of the grapevine trunk disease “Esca” – a deadly fungal disease that does not have a cure to date. We have developed a reliable protocol, based on modified wood components, that entrap a fungicide and allow a direct transport inside of a living plant and to treat the disease at the place of action – such a nanocarrier-mediated drug delivery for plants will reduce the amounts of pesticides which are sprayed on the fields in the agriculture in general.

Fully synthetic polyethylene-mimics are another major topic in this research area. We design monomers with breaking points, e.g. phosphoesters or orthoesters, that undergo hydrolysis or enzymatic cleavage under certain conditions. These very hydrophobic polymers might be able to replace the non-biodegradable polyethylene is certain applications as they ensure complete degradation. Further information can be found via the link of the interdisciplinary project “PlastX”.

Besides research on novel biodegradable polymers, we also conduct studies about commodity plastics and packaging. The results are published together with the PlastX workgroup (see external link). Shorter stories about plastics and packaging are currently published online via the institute’s Twitter account and cover for example explanations about “To Go”-products or biodegradable waste bags for organic waste. In a recent article (Haider et al. Angew. Chem 2019), we discuss the term “biodegradability” – and compare test methods from the lab to real-life applications that concern the biodegradability of plastics and polymers.

Sequence-controlled copolymers


Even 60 years after its discovery, living anionic polymerization is still the method of choice, when it comes to well-defined polymers of high molar mass, end-group functionality, block copolymers. The anionic polymerization is also very important in the industry to prepare block copolymers from vinyl monomers or epoxides, for example. The high control of the anionic polymerization allows also controlling comonomer sequences, either by sequential polymerization or a competing copolymerization of several monomers.

SPC develops comonomer systems, which undergo a selective sequenced copolymerization. By monomer design, we control the polymerization kinetics in order to prepare block copolymers (Gleede et al. J. Am. Chem. Soc. 2018) or (multi) gradient copolymers (Rieger et al. Angew. Chem. 2018 & Macromol. Rapid Comm. 2016).

In contrast to solid-supported synthetic strategies, our approach allows us to prepare sophisticated macromolecules on a large scale with high structural precision. The monomer design controls the reactivity.

A synthetic platform to realize such sequenced copolymers was established in the SPC in recent years: the living anionic polymerization of aziridines. Aziridines were missing in the monomer family for anionic polymerization and access to well-defined polyamine structures or copolymers with styrenes or epoxides are challenging or even impossible to prepare. Aziridine, or ethylene imine, is produced industrially and polymerized only by uncontrolled cationic polymerization. It has a plethora of applications, ranging from chelator, and wastewater treatment to gene transfection. The combination of such building blocks with other industrially relevant materials would be desirable to prepare novel materials with unprecedented properties. However, controlled synthesis of linear or branched poly(ethylene imine) (PEI) from aziridine had been missing. The only way for preparing linear PEI is the detour via oxazoline chemistry and subsequent hydrolysis. We established a novel monomer family for the living anionic polymerization, namely activated aziridines. By activation of the aziridine-ring with sulfonamides to allow nucleophilic ring opening, a variety of novel monomers and polymers becomes available. More importantly, base-initiated polymerization proceeds via a “living” mechanism, allowing the formation of polymer architectures or combinations with other monomer types. We were able to introduce several chemical functions into the polyaziridines, either in the activating group or as a pendant chain. Removal of the activating group, if desired, is possible by several methods to prepare polyamines which were not accessible so far.

The activating group can do more: by adjustment of the electron-withdrawing effect, the sulfonamide finely tunes the monomer reactivity and controls the synthetic primary structure. This allowed us to prepare sequence-controlled copolymers by a competing anionic polymerization of up to 5 different monomers in a one-pot and one-shot reaction (Macromol. Rapid Comm. 2016). This will allow us to prepare functional materials mimicking the primary structure of proteins and allow folding into hierarchical assemblies. In addition, chirality is currently installed into such synthetic primary structures to further control the chirality of the folding. The combination of aziridine chemistry with epoxides allowed us to prepare amphiphilic multi-block copolymers.

Compartmentalization is another handle to control the synthetic primary structure: By confining a copolymerization to nanodroplets in an emulsion, an ideal (random) copolymerization is forced into gradient copolymers. Polymerization began only inside the droplets. As that compound was gradually consumed, the change in concentration pulled ever-greater amounts of the other ingredient into the chains, creating a gradient effect.

Publications

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2026

Renewable coatings from liquefied wood: Linking epoxide structure to material properties and chemical recyclability (2026)Polymer, 348. Article 129680 (E-pub ahead of print/First online). Hu, Q., Brockötter, S., Lange, J.-P., Ruiz, M. P., Struck, C. & Wurm, F. R.https://doi.org/10.1016/j.polymer.2026.129680Facilitating Polylactide’s End-of-Life: Nutrient-Loaded Silica Nanoparticles Enhance Environmental Biodegradation in Bulk and in 3D-Printed Structures (2026)ACS sustainable chemistry & engineering, 14(3), 1331-1340. Zhu, X., Hempenius, M. A., Gojzewski, H. & Wurm, F. R.https://doi.org/10.1021/acssuschemeng.5c09739Cationic copolymerization of furfural and furfural-derived 3,4-dihydropyran: biobased and biodegradable polyacetals with high glass transition temperatures (2026)European polymer journal, 242. Article 114454. Illari, D., Zhu, X., Hempenius, M. A. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2025.114454Degradable polyphosphoester-based aqueous two-phase systems and water-in-water emulsions (2026)Chemical science (E-pub ahead of print/First online). McCone, J. A. J., Elshof, R. t., Bayliss, N., Wurm, F. R. & Schmidt, B. V. K. J.https://doi.org/10.1039/d5sc09406bGlutathione and Laccase Dual-Responsive Lignin Nanocarriers Inspired by Host-Pathogen Interactions for Fungicide Delivery (2026)Advanced functional materials, 36(2). Article e11202. Liang, W., Cheng, J., Liu, L., Zhao, J. & Wurm, F. R.https://doi.org/10.1002/adfm.202511202Biodegradable and water-soluble polymers in block copolymer architectures (2026)Polymer degradation and stability, 243. Article 111749. Azhdari, S., Gröschel, A. H. & Wurm, F. R.https://doi.org/10.1016/j.polymdegradstab.2025.111749

2025

Dual-Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers (2025)Advanced healthcare materials. Article e04352 (E-pub ahead of print/First online). Kötzsche, M., Dzierza, A., Egger, J., Rheinberger, T., Weilandt, C., Wurm, F. R., Nischang, I., Fischer, D. & Peneva, K.https://doi.org/10.1002/adhm.202504352Degradable and Recyclable 3D-Printed Pheromones Delivery System Reinforced by Metal Coordination Cross-Linking for Efficient Pest Trapping (2025)Advanced science. Article e09712 (E-pub ahead of print/First online). Wang, T., Shangguan, W., Zhang, F., Liang, W., Wurm, F. R., Huang, Q. & Cao, L.https://doi.org/10.1002/advs.202509712Mimicking Block Copolymer Self-Assembly with One-Pot Synthesized Polyphosphoester Gradient Copolymers (2025)Advanced functional materials. Article e26728 (E-pub ahead of print/First online). Azhdari, S., Rheinberger, T., Mansfeld, U., Post, Y., Linders, J., Koshkina, O., Gröschel, A. H. & Wurm, F. R.https://doi.org/10.1002/adfm.202526728Fully Bio-Based Epoxy Resins from Liquefied Wood for Chemically Recyclable Wood Coatings (2025)Advanced functional materials, 35(38). Article 2502689. Hu, Q., Martinho, R. P., Azhdari, S., Lange, J.-P., van Drongelen, M., Ruiz, M. P. & Wurm, F. R.https://doi.org/10.1002/adfm.202502689In vitro imaging of Raji B cells with fluorescent and biocompatible lipidic cubosomes (2025)European polymer journal, 235. Article 114078. Fornasier, M., Junghans, V., Schillén, K., Nylander, T., Teràn, J. C., Wurm, F. R., Jönsson, P. & Murgia, S.https://doi.org/10.1016/j.eurpolymj.2025.114078Oil-in-Water Pickering Emulsions Stabilized by Lignin Nanoparticles with Different Molecular Structures (2025)ACS sustainable chemistry & engineering, 13(29), 11266-11275. Gao, K., Hempenius, M. A., Sui, X., Wurm, F. R. & Vancso, G. J.https://doi.org/10.1021/acssuschemeng.5c01896The Horizon Europe NEWGEN Research Project: For a New Generation of High-Voltage DC Insulation Materials, Cables, and Systems after 24 Months since the Start of the Project (2025)IEEE Industry Applications Magazine, 31(4), 72-82. Mazzanti, G., Wurm, F., Vergine, C., Diban, B., Ciroth, A., Paajanen, M., Harjuhahto, J., Lahti, K., Pieroni, P., Kannampuzha, M., Rytoluoto, I., Caprara, A., Niittymaki, M. & Leproux, A.https://doi.org/10.1109/MIAS.2025.3559863Side Chain Length Impact of Linear Polyamines on Filtration Properties in Polyelectrolyte Multilayer Membranes (2025)ACS Applied Polymer Materials, 7(12), 7966-7975. Hagedoorn, D., Bockhard, C., Achterhuis, I., te Brinke, E., de Vos, W. M. & Wurm, F. R.https://doi.org/10.1021/acsapm.5c00993Towards sustainable 3D Printing: A biodegradable hybrid resin from avocado oil and lignin (2025)European polymer journal, 234. Article 114006. Yoe, L. E. A. C., Zhu, X., Ruiz Deance, A. L., Hagedoorn, D., Wurm, F. R. & Gojzewski, H.https://doi.org/10.1016/j.eurpolymj.2025.114006Kunststoffe der Zukunft? Interdisziplinäre Analyse biobasierter und biologisch abbaubarer Polymere: Fortschritte in der Chemie, gesellschaftliche Perspektiven und ökologische Auswirkungen (2025)Angewandte Chemie, 137(23). Article e202423406. Velasquez, S. T. R., Hu, Q., Kramm, J., Santin, V. C., Völker, C. & Wurm, F. R.https://doi.org/10.1002/ange.202423406Plastics of the Future? An Interdisciplinary Review on Biobased and Biodegradable Polymers: Progress in Chemistry, Societal Views, and Environmental Implications (2025)Angewandte Chemie (international edition), 64(23). Article e202423406. Velasquez, S. T. R., Hu, Q., Kramm, J., Santin, V. C., Völker, C. & Wurm, F. R.https://doi.org/10.1002/anie.202423406Unlocking complexity through neutron scattering: Structure and dynamics of protein–polymer conjugates (2025)Protein science, 34(6). Article e70137. Russo, D., Wurm, F. & Teixeira, J.https://doi.org/10.1002/pro.70137Rubber-like and Antifouling Poly(trimethylene carbonate-ethylphosphonate) Copolymers with Tunable Hydrolysis (2025)ACS Applied Materials and Interfaces, 17(16), 23513-23521. Rheinberger, T., Ankone, M. J. K., Grijpma, D. W. & Wurm, F. R.https://doi.org/10.1021/acsami.4c21079The Environmental Impact of Medical Imaging Agents and the Roadmap to Sustainable Medical Imaging (2025)Advanced science, 12(9). Article 2404411. Pichler, V., Martinho, R. P., Temming, L., Segers, T., Wurm, F. R. & Koshkina, O.https://doi.org/10.1002/advs.202404411Metal Ions in Polydopamine Coatings Enhance Polymer-Metal Adhesion (2025)ACS Applied Polymer Materials, 7(4), 2408-2418. Kafkopoulos, G., Martinho, R. P., Padberg, C. J., Duvigneau, J., Wurm, F. R. & Vancso, G. J.https://doi.org/10.1021/acsapm.4c03551Water-harvesting polymer coatings for plant leaves (2025)RSC Applied Polymers, 3(1), 173-180. Milatz, R., Reink, C., van den Berg, T. E., Duvigneau, J., Vancso, J. & Wurm, F. R.https://doi.org/10.1039/D4LP00249K

2024

Super-resolution Optoacoustic Imaging of Cerebral Microcirculation with Indocyanine Green Microcapsules (2024)ACS photonics, 11(11), 4642-4647. Tang, L., Nozdriukhin, D., Özsoy, C., Chen, Y., Wrum, F. R., Koshkina, O., Razansky, D. & Deán-Ben, X. L.https://doi.org/10.1021/acsphotonics.4c01050Updates About the Horizon Europe NEWGEN Research Project for a New Generation of HVDC Insulation Materials, Cables and Systems (2024)In Proceedings - 24th EEEIC International Conference on Environment and Electrical Engineering and 8th I and CPS Industrial and Commercial Power Systems Europe, EEEIC/I and CPS Europe 2024. IEEE. Mazzanti, G., Paajanen, M., Rytöluoto, I., Wurm, F., Harjuhahto, J., Caprara, A., Vergine, C., Lahti, K., Niittymäki, M., Diban, B., Pieroni, P., Mourad, M., Ciroth, A. & Kannampuzha, M.https://doi.org/10.1109/EEEIC/ICPSEurope61470.2024.10751490The Effects of Tomato Intercropping with Medicinal Aromatic Plants Combined with Trichoderma Applications in Organic Cultivation (2024)Agronomy, 14(11). Article 2572. Szczech, M., Kowalska, B., Wurm, F. R., Ptaszek, M., Jarecka-Boncela, A., Trzciński, P., Borup Løvschall, K., Roldan Velasquez, S. T. & Maciorowski, R.https://doi.org/10.3390/agronomy14112572Degradable Polymer Architectures Based on Polyphosphonate, Poly(2-oxazoline), and Poly(2-oxazine) (2024)Macromolecules, 57(20), 9853-9866. Gadaga, R., Varanaraja, Z., Lefley, J., Rheinberger, T., Wurm, F. R. & Becer, C. R.https://doi.org/10.1021/acs.macromol.4c01974Helical polyamines (2024)Chemical science, 15(39), 16377-16390. Hagedoorn, D., Michel-Souzy, S., Gostyński, B., Gojzewski, H., Paneth, P., Cornelissen, J. J. L. M. & Wurm, F. R.https://doi.org/10.1039/d4sc05129gBiobased Flame-Retardant Polylactic Acid Foams through Lignin-Based Nanocarriers Encapsulating Deoxyribonucleic Acid (2024)ACS sustainable chemistry & engineering, 12(40), 14866-14878. Ridard, H., Duvigneau, J., Mayer-Gall, T., Ali, W. & Wurm, F. R.https://doi.org/10.1021/acssuschemeng.4c05886Fully Degradable Polyphosphoester Cubosomes for Sustainable Agrochemical Delivery (2024)Advanced materials, 36(38). Article 2406831. Azhdari, S., Linders, J., Coban, D., Stank, T. J., Dargel, C., Gojzewski, H., Hellweg, T., Gröschel, A. H. & Wurm, F. R.https://doi.org/10.1002/adma.202406831Polyphosphoester-stabilized cubosomes encapsulating a Ru(II) complex for the photodynamic treatment of lung adenocarcinoma (2024)Journal of colloid and interface science, 670, 234-245. Casula, L., Giacomazzo, G. E., Conti, L., Fornasier, M., Manca, B., Schlich, M., Sinico, C., Rheinberger, T., Wurm, F. R., Giorgi, C. & Murgia, S.https://doi.org/10.1016/j.jcis.2024.05.088Characterization of Isotactic-Polypropylene-Based Compounds for HVDC Cable Insulation (2024)In 2024 IEEE 5th International Conference on Dielectrics (ICD). IEEE. Diban, B., Mazzanti, G., Seri, P., Paajanen, M., Rytoluoto, I., Saarimaki, E., Lahti, K., Niittymaki, M., Mourad, M., Leproux, A., Anyszka, R., Wurm, F. R., Palmieri, L. & Rheinberger, T.https://doi.org/10.1109/ICD59037.2024.10613139Screening of Suitable Random Copolymer Polypropylene Blends for HVDC Cable Insulation (2024)In 2024 IEEE 5th International Conference on Dielectrics (ICD). IEEE. Niittymaki, M., Lahti, K., Rytöluoto, I., Saarimaki, E., Paajanen, M., Diban, B., Seri, P., Mazzanti, G., Mourad, M., Leproux, A., Anyszka, R., Wurm, F. R. & Rheinberger, T.https://doi.org/10.1109/ICD59037.2024.10613125Creating Anti-Biofouling Surfaces by Degradable Main-chain Polyphosphoester Polymer Brushes (2024)Advanced functional materials, 34(32). Article 2316201. Brió Pérez, M., Resendiz-Lara, D. A., Matsushita, Y., Kakinoki, S., Iwasaki, Y., Hempenius, M. A., de Beer, S. & Wurm, F. R.https://doi.org/10.1002/adfm.202316201Accelerated hydrolysis and degradation of polylactide nanocomposites using loaded silica nanocarriers (2024)Chemical Engineering Journal, 491. Article 151903. Zhu, X., Gojzewski, H., Koshkina, O. & Wurm, F. R.https://doi.org/10.1016/j.cej.2024.151903Enhancing Stability and Efficacy of Trichoderma Bio-Control Agents Through Layer-by-Layer Encapsulation for Sustainable Plant Protection (2024)Advanced Sustainable Systems, 8(7). Article 2300409. Borup Løvschall, K., Velasquez, S. T. R., Kowalska, B., Ptaszek, M., Jarecka, A., Szczech, M. & Wurm, F. R.https://doi.org/10.1002/adsu.202300409Investigation of the structure of protein–polymer conjugates in solution reveals the impact of protein deuteration and the size of the polymer on its thermal stability (2024)Protein science, 33(6). Article e5032. Russo, D., Di Venere, A., Wurm, F. R., Moulin, M., Härtlein, M., Garvey, C. J. & Teixeira, J.https://doi.org/10.1002/pro.5032Encapsulation of Ammonium Polyphosphate in Lignin Nanocontainers Enhances Dispersion and Flame Retardancy in Polylactic Acid Foams (2024)ACS Applied Polymer Materials, 6(10), 6096-6107. Peil, S., Mouhoubi, R., Streekstra, R., Ridard, H., Veith, L., Ali, W., Mayer-Gall, T., Duvigneau, J. & Wurm, F. R.https://doi.org/10.1021/acsapm.4c00787Multi-Stimuli-Responsive, Topology-Regulated, and Lignin-Based Nano/Microcapsules from Pickering Emulsion Templates for Bidirectional Delivery of Pesticides (2024)ACS nano, 18(14), 10031-10044. Yu, B., Cheng, J., Fang, Y., Xie, Z., Xiong, Q., Zhang, H., Shang, W., Wurm, F. R., Liang, W., Wei, F. & Zhao, J.https://doi.org/10.1021/acsnano.3c11621On the Road to Circular Polymer Brushes: Challenges and Prospects (2024)Langmuir, 40(14), 7249-7256. Brió Pérez, M., Wurm, F. R. & de Beer, S.https://doi.org/10.1021/acs.langmuir.3c03683Polypropylene Copolymers and Blends for HVDC Cable Insulation: Initial Characterization and Pilot-scale Production (2024)In 2024 IEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2024 (Proceedings IEEE Conference on Electrical Insulation and Dielectric Phenomena (CEIDP); Vol. 2024). IEEE. Diban, B., Mazzanti, G., Seri, P., Diaz, R. E., Rytoluoto, I., Paajanen, M., Saarimaki, E., Lahti, K., Niittymaki, M., Mourad, M., Leproux, A., Anyszka, R., Wurm, F. & Rheinberger, T.https://doi.org/10.1109/CEIDP61745.2024.10907748Stealth Behavior of Poly(ethyloxazoline)s-Modified Hydroxyethyl Starch-Based Nanocapsules (2024)Journal of the Brazilian Chemical Society, 35(7). Article e-20240019. Fechine, L. M. U. D., Kang, B., Schöttler, S., Moreira, D. R., Queiroz, D. C., Wurm, F. R., Landfester, K. & Ricardo, N. M. P. S.https://doi.org/10.21577/0103-5053.20240019

2023

Copolymerizing Lignin for Tuned Properties of 3D-Printed PEG-Based Photopolymers (2023)ACS Applied Polymer Materials, 5(12), 10021–10031. Ruiz Deance, A. L., Siersema, B., Yoe, L. E. A. C., Wurm, F. R. & Gojzewski, H.https://doi.org/10.1021/acsapm.3c01875Superbase-enabled anionic polymerization of poly(alkyl cyanoacrylate)s: achieving well-defined structures and controlled molar masses (2023)Polymer international, 72(12), 1079-1083. Hüppe, N., Gleede, T. & Wurm, F. R.https://doi.org/10.1002/pi.6556Towards more homogeneous character in 3D printed photopolymers by the addition of nanofillers (2023)Polymer testing, 129. Article 108243. Robakowska, M., Gibson, I., Akkerman, R., Wurm, F. R. & Gojzewski, H.https://doi.org/10.1016/j.polymertesting.2023.108243The future of polyphosphoesters (2023)European polymer journal, 200. Article 112464. Rheinberger, T., Rabaux, O., Jérôme, C. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2023.112464Polyester Brush Coatings for Circularity: Grafting, Degradation, and Repeated Growth (2023)Macromolecules, 56(21), 8856–8865. Brió Pérez, M., Hempenius, M. A., de Beer, S. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.3c01601Water-soluble polyphosphonate-based bottlebrush copolymers via aqueous ring-opening metathesis polymerization (2023)Chemical science, 14(40), 11273-11282. Resendiz-Lara, D. A., Azhdari, S., Gojzewski, H., Gröschel, A. H. & Wurm, F. R.https://doi.org/10.1039/d3sc02649cAll-Lignin Polyelectrolyte Multilayers as Renewable and Biodegradable Nanofiltration Membranes (2023)ACS Applied Polymer Materials, 5(10), 8547-8558. Watt, T. R., Peil, S., Jonkers, W. A., Regenspurg, J. A., Wurm, F. R. & de Vos, W. M.https://doi.org/10.1021/acsapm.3c01661Real-time 31P NMR reveals different gradient strengths in polyphosphoester copolymers as potential MRI-traceable nanomaterials (2023)Communications Chemistry, 6(1). Article 182. Rheinberger, T., Flögel, U., Koshkina, O. & Wurm, F. R.https://doi.org/10.1038/s42004-023-00954-xNanocarriers with Multiple Cargo Load—A Comprehensive Preparation Guideline Using Orthogonal Strategies (2023)Macromolecular rapid communications, 44(16). Article 2200611. Hueppe, N., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/marc.202200611Biobased Agents for Single‐Particle Detection with Optoacoustics (2023)Small, 19(29). Article 2207199. Chen, Y., Nozdriukhin, D., Michel-Souzy, S., Padberg, C., Wurm, F. R., Razansky, D., Deán‐Ben, X. L. & Koshkina, O.https://doi.org/10.1002/smll.202207199Biodegradable polyphosphoester micelles act as both background-free 31P magnetic resonance imaging agents and drug nanocarriers (2023)Nature communications, 14(1). Article 4351. Koshkina, O., Rheinberger, T., Flocke, V., Windfelder, A., Bouvain, P., Hamelmann, N. M., Paulusse, J. M. J., Gojzewski, H., Flögel, U. & Wurm, F. R.https://doi.org/10.1038/s41467-023-40089-0Nanoscale Control of the Surface Functionality of Polymeric 2D Materials (2023)Small, 19(25). Article 2206454. Suraeva, O., Kaltbeitzel, A., Landfester, K., Wurm, F. R. & Lieberwirth, I.https://doi.org/10.1002/smll.202206454The microstructure of polyphosphoesters controls polymer hydrolysis kinetics from minutes to years (2023)European polymer journal, 190. Article 111999. Rheinberger, T., Deuker, M. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2023.111999Confining the Sol-Gel Reaction at the Water/Oil Interface: Creating Compartmentalized Enzymatic Nano-Organelles for Artificial Cells (2023)Angewandte Chemie (international edition), 62(11). Article e202216966. Gonçalves, J. P., Promlok, D., Ivanov, T., Tao, S., Rheinberger, T., Jo, S. M., Yu, Y., Graf, R., Wagner, M., Crespy, D., Wurm, F. R., Caire da Silva, L., Jiang, S. & Landfester, K.https://doi.org/10.1002/anie.202216966Acceleration of Biodegradation Using Polymer Blends and Composites (2023)Macromolecular chemistry and physics, 224(6). Article 2200421. Easton, Z. H. W., Essink, M. A. J., Rodriguez Comas, L., Wurm, F. R. & Gojzewski, H.https://doi.org/10.1002/macp.202200421AFM monitoring of the cut surface of a segmented polyurethane unveils a microtome-engraving induced growth process of oriented hard domains (2023)Polymer testing, 120. Article 107961. Gojzewski, H., van Drongelen, M., Imre, B., Hempenius, M. A., Check, C., Chartoff, R., Wurm, F. R. & Vancso, G. J.https://doi.org/10.1016/j.polymertesting.2023.107961Reversible acetalization of cellulose: A platform for bio-based materials with adjustable properties and biodegradation (2023)Chemical Engineering Journal, 452(Part 3). Article 139280. Peil, S., Gojzewski, H. & Wurm, F. R.https://doi.org/10.1016/j.cej.2022.139280The NEWGEN European Union Research Project for a New Generation of HVDC Cable Systems (2023)In 2023 AEIT HVDC International Conference, AEIT HVDC 2023. IEEE. Mazzanti, G., Paajanen, M., Rytoluoto, I., Harjuhahto, J., Caprara, A., Wurm, F., Lahti, K., Ciroth, A., Leproux, A., Kannampuzha, M. & Vergine, C.https://doi.org/10.1109/AEITHVDC58550.2023.10179056„Chemistry for a Sustainable Society“ – 8th Sino-German Frontiers of Chemistry Symposium (2023)Nachrichten aus der Chemie, 71(1), 88. Weinig, H. G., Wurm, F. & Nuhn, L.https://doi.org/10.1002/nadc.20234133979

2022

End-of-life biodegradation? how to assess the composting of polyesters in the lab and the field (2022)Waste management, 154, 36-48. Mouhoubi, R., Lasschuijt, M., Ramon Carrasco, S., Gojzewski, H. & Wurm, F. R.https://doi.org/10.1016/j.wasman.2022.09.025Environment-friendly transesterification to seawater-degradable polymers expanded: Computational construction guide to breaking points (2022)Chemosphere, 308(Part 2). Article 136381. Pokora, M., Rheinberger, T., Wurm, F. R., Paneth, A. & Paneth, P.https://doi.org/10.1016/j.chemosphere.2022.136381Real-Time 1H and 31P NMR spectroscopy of the copolymerization of cyclic phosphoesters and trimethylene carbonate reveals transesterification from gradient to random copolymers (2022)European polymer journal, 180. Article 111607. Rheinberger, T., Ankone, M., Grijpma, D. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2022.111607Lignin-based non-crosslinked nanocarriers: A promising delivery system of pesticide for development of sustainable agriculture (2022)International journal of biological macromolecules, 220, 472-481. Liang, W., Zhang, J., Wurm, F. R., Wang, R., Cheng, J., Xie, Z., Li, X. & Zhao, J.https://doi.org/10.1016/j.ijbiomac.2022.08.103Unfreezing of molecular motions in protein-polymer conjugates: a calorimetric study (2022)Journal of Thermal Analysis and Calorimetry, 147(22), 12631-12639. Pelosi, C., Tombari, E., Wurm, F. R. & Tiné, M. R.https://doi.org/10.1007/s10973-022-11437-xTrithiocarbonate-Mediated RAFT Polymerization Enables the Synthesis of Homotelechelic N-Vinylpyrrolidone Oligomers with Surfactant Properties (2022)ACS Applied Polymer Materials, 4(10), 6863-6870. Gapin, A. & Wurm, F. R.https://doi.org/10.1021/acsapm.2c00796Correction to: Multimodal Enzyme-Carrying Suprastructures for Rapid and Sensitive Biocatalytic Cascade Reactions (Advanced Science, (2022), 9, 10, (2104884), 10.1002/advs.202104884) (2022)Advanced science, 9(27). Article 2204665. Jo, S.-M., Kim, J., Lee, J. E., Wurm, F. R., Landfester, K. & Wooh, S.https://doi.org/10.1002/advs.202204665A circular dichroism study of the protective role of polyphosphoesters polymer chains in polyphosphoester-myoglobin conjugates (2022)Chirality, 34(9), 1257-1265. Pelosi, C., Arrico, L., Zinna, F., Wurm, F. R., Di Bari, L. & Tinè, M. R.https://doi.org/10.1002/chir.23486Multicomponent encapsulation into fully degradable protein nanocarriers via interfacial azide-alkyne click reaction in miniemulsion allows the co-delivery of immunotherapeutics (2022)Nanoscale Horizons, 7(8), 908-915. Hüppe, N., Schunke, J., Fichter, M., Mailänder, V., Wurm, F. R. & Landfester, K.https://doi.org/10.1039/d2nh00243dDual-Targeted Nanoreactors and Prodrugs: Hydrogen Peroxide Triggers Oxidative Damage and Prodrug Activation for Synergistic Elimination of Cancer Cells (2022)Advanced functional materials, 32(26). Article 2200791. Jo, S. M., Kim, H. S., Won, M., Champanhac, C., Kim, J. S., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/adfm.202200791Biopolymer-based nanocarriers for sustained release of agrochemicals: A review on materials and social science perspectives for a sustainable future of agri- and horticulture (2022)Advances in colloid and interface science, 303. Article 102645. Machado, T. O., Grabow, J., Sayer, C., de Araújo, P. H. H., Ehrenhard, M. L. & Wurm, F. R.https://doi.org/10.1016/j.cis.2022.102645Multimodal Enzyme-Carrying Suprastructures for Rapid and Sensitive Biocatalytic Cascade Reactions (2022)Advanced science, 9(10). Article 2104884. Jo, S. M., Kim, J., Lee, J. E., Wurm, F. R., Landfester, K. & Wooh, S.https://doi.org/10.1002/advs.202104884Blood Compatibility of Hydrophilic Polyphosphoesters (2022)ACS Applied Bio Materials, 5(3), 1151-1158. Pelosi, C., Constantinescu, I., Son, H. H., Tinè, M. R., Kizhakkedathu, J. N. & Wurm, F. R.https://doi.org/10.1021/acsabm.1c01210

2021

RNA-inspired intramolecular transesterification accelerates the hydrolysis of polyethylene-like polyphosphoesters (2021)Chemical science, 12(48), 16054-16064. Haider, T. P., Suraeva, O., Lieberwirth, I., Paneth, P. & Wurm, F. R.https://doi.org/10.1039/d1sc05509gDevelopment of physical, mechanical, antibacterial and cell growth properties of poly(glycerol sebacate urethane) (PGSU) with helping of curcumin and hydroxyapatite nanoparticles (2021)Polymer chemistry, 12(43), 6263-6282. Fakhri, V., Jafari, A., Shafiei, M. A., Ehteshamfar, M. V., Khalighiyan, S., Hosseini, H., Goodarzi, V., Wurm, F. R., Moosazadeh Moghaddam, M. & Khonakdar, H. A.https://doi.org/10.1039/d1py01040aCellulose nanocarriers via miniemulsion allow Pathogen-Specific agrochemical delivery (2021)Journal of colloid and interface science, 601, 678-688. Machado, T. O., Beckers, S. J., Fischer, J., Sayer, C., Araújo, P. H. H. d., Landfester, K. & Wurm, F. R.https://doi.org/10.1016/j.jcis.2021.05.030Polyphosphonate-Based Macromolecular RAFT-CTA Enables the Synthesis of Well-Defined Block Copolymers Using Vinyl Monomers (2021)ACS macro letters, 10, 1273-1279. Resendiz-Lara, D. A. & Wurm, F. R.https://doi.org/10.1021/acsmacrolett.1c00564RNA-Inspired and Accelerated Degradation of Polylactide in Seawater (2021)Journal of the American Chemical Society, 143(40), 16673-16681. Rheinberger, T., Wolfs, J., Paneth, A., Gojzewski, H., Paneth, P. & Wurm, F. R.https://doi.org/10.1021/jacs.1c07508Terpyridine-Induced Folding of Anisotropic Polyphosphoester Platelets (2021)ACS Polymers Au. Haider, T. P., Suraeva, O., Lieberwirth, I. & Wurm, F. R.https://doi.org/10.1021/acspolymersau.1c00021Amphiphilic polyphosphonate copolymers as new additives for pdms‐based antifouling coatings (2021)Polymers, 13(19). Article 3414. Guazzelli, E., Lusiani, N., Monni, G., Oliva, M., Pelosi, C., Wurm, F. R., Pretti, C. & Martinelli, E.https://doi.org/10.3390/polym13193414Facile template preparation of novel electroactive scaffold composed of polypyrrole-coated poly(glycerol-sebacate-urethane) for tissue engineering applications (2021)European polymer journal, 159. Article 110749. Golbaten-Mofrad, H., Seyfi Sahzabi, A., Seyfikar, S., Salehi, M. H., Goodarzi, V., Wurm, F. R. & Jafari, S. H.https://doi.org/10.1016/j.eurpolymj.2021.110749New Technologies are Needed to Improve the Recycling and Upcycling of Waste Plastics (2021)ChemSusChem, 14(19), 3982-3984. Ragauskas, A. J., Huber, G. W., Wang, J., Guss, A., O'Neill, H. M., Lin, C. S. K., Wang, Y., Wurm, F. R. & Meng, X.https://doi.org/10.1002/cssc.202101872Surface modification of porous polyethylene implants with an albumin-based nanocarrier-release system (2021)Biomedicines, 9(10). Article 1485. Eckrich, J., Hoormann, N., Kersten, E., Piradashvili, K., Wurm, F. R., Heller, M., Becker, S., Anusic, T., Brieger, J. & Strieth, S.https://doi.org/10.3390/biomedicines9101485Progress on Stimuli-Responsive Polymers (2021)Macromolecular rapid communications, 42(18). Article 2100512. Wurm, F. R., Boyer, C. & Sumerlin, B. S.https://doi.org/10.1002/marc.202100512Synthetic lignin-like and degradable nanocarriers (2021)Polymer chemistry, 12(32), 4661-4667. Beckers, S. J., Fischer, J. & Wurm, F. R.https://doi.org/10.1039/d1py00818hGreen synthesis and characterization of poly(glycerol-azelaic acid) and its nanocomposites for applications in regenerative medicine (2021)Journal of applied polymer science, 138(24). Article 50563. Chenani, F. H., Rezaei, V. F., Fakhri, V., Wurm, F. R., Uzun, L. & Goodarzi, V.https://doi.org/10.1002/app.50563Targeted Drug Delivery for Sustainable Crop Protection: Transport and Stability of Polymeric Nanocarriers in Plants (2021)Advanced science, 8(11). Article 2100067. Beckers, S. J., Staal, A. H. J., Rosenauer, C., Srinivas, M., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/advs.202100067Effect of Polymer Hydrophilicity and Molar Mass on the Properties of the Protein in Protein-Polymer Conjugates: The Case of PPEylated Myoglobin (2021)Biomacromolecules, 22(5), 1932-1943. Pelosi, C., Duce, C., Wurm, F. R. & Tine, M. R.https://doi.org/10.1021/acs.biomac.1c00058Polymer defect engineering - conductive 2D organic platelets from precise thiophene-doped polyethylene (2021)Polymer chemistry, 12(14), 2045-2053. Suraeva, O., Jeong, B., Asadi, K., Landfester, K., Wurm, F. R. & Lieberwirth, I.https://doi.org/10.1039/d1py00117eEnzyme-Loaded Nanoreactors Enable the Continuous Regeneration of Nicotinamide Adenine Dinucleotide in Artificial Metabolisms (2021)Angewandte Chemie (international edition), 60(14), 7728-7734. Jo, S.-M., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/anie.202012023Display of hidden properties of flexible aerogel based on bacterial cellulose/polyaniline nanocomposites with helping of multiscale modeling (2021)European polymer journal, 146. Article 110251. Hosseini, H., Mousavi, S. M., Wurm, F. R. & Goodarzi, V.https://doi.org/10.1016/j.eurpolymj.2020.110251Anticancer effect of green tea extract (GTE)-Loaded pH-responsive niosome Coated with PEG against different cell lines (2021)Materials today communications, 26. Article 101751. Baranei, M., Taheri, R. A., Tirgar, M., Saeidi, A., Oroojalian, F., Uzun, L., Asefnejad, A., Wurm, F. R. & Goodarzi, V.https://doi.org/10.1016/j.mtcomm.2020.101751Conformation of Myoglobin-Poly(Ethyl Ethylene Phosphate) Conjugates Probed by SANS: Correlation with Polymer Grafting Density and Interaction (2021)Macromolecular bioscience, 21(2). Article 2000356. Russo, D., Garvey, C. J., Wurm, F. R. & Teixeira, J.https://doi.org/10.1002/mabi.202000356

2020

Aqueous core and hollow silica nanocapsules for confined enzyme modules (2020)Nanoscale, 12(47), 24266-24272. Jo, S. M., Jiang, S., Graf, R., Wurm, F. R. & Landfester, K.https://doi.org/10.1039/d0nr07148jPesticide-Loaded Nanocarriers from Lignin Sulfonates - A Promising Tool for Sustainable Plant Protection (2020)ACS sustainable chemistry & engineering, 8(50), 18468-18475. Beckers, S., Peil, S. & Wurm, F. R.https://doi.org/10.1021/acssuschemeng.0c05897Defect engineering of polyethylene-like polyphosphoesters: solid-state NMR characterization and surface chemistry of anisotropic polymer nanoplatelets (2020)Polymer chemistry, 11(45), 7235-7243. Markwart, J. C., Suraeva, O., Haider, T., Lieberwirth, I., Graf, R. & Wurm, F. R.https://doi.org/10.1039/D0PY01352HMain-chain water-soluble polyphosphoesters: Multi-functional polymers as degradable PEG-alternatives for biomedical applications (2020)European polymer journal, 141. Article 110079. Pelosi, C., Tinè, M. R. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2020.110079Poly(methyl ethylene phosphate) hydrogels: Degradable and cell-repellent alternatives to PEG-hydrogels (2020)European polymer journal, 141. Article 110075. Tee, H. T., Zipp, R., Koynov, K., Tremel, W. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2020.110075Developing antibacterial superhydrophobic coatings based on polydimethylsiloxane/silver phosphate nanocomposites: Assessment of surface morphology, roughness and chemistry (2020)Progress in organic coatings, 149. Article 105944. Seyfi, J., Goodarzi, V., Wurm, F. R., Shojaei, S., Jafari-Nodoushan, M., Najmoddin, N., Khonakdar, H. A., Baghersad, M. H. & Uzun, L.https://doi.org/10.1016/j.porgcoat.2020.105944Fungicide-loaded and biodegradable xylan-based nanocarriers (2020)Biopolymers, 111(12). Article e23413. Beckers, S. J., Wetherbee, L., Fischer, J. & Wurm, F. R.https://doi.org/10.1002/bip.23413Cubosomes stabilized by a polyphosphoester-analog of Pluronic F127 with reduced cytotoxicity (2020)Journal of colloid and interface science, 580, 286-297. Fornasier, M., Biffi, S., Bortot, B., Macor, P., Manhart, A., Wurm, F. R. & Murgia, S.https://doi.org/10.1016/j.jcis.2020.07.038Crystallization of poly(Ethylene)s with regular phosphoester defects studied at the air–water interface (2020)Polymers, 12(10), 1-16. Article 2408. Hasan, N., Busse, K., Haider, T., Wurm, F. R. & Kressler, J.https://doi.org/10.3390/polym12102408Polyphosphoester surfactants as general stealth coatings for polymeric nanocarriers (2020)Acta biomaterialia, 116, 318-328. Bauer, K. N., Simon, J., Mailänder, V., Landfester, K. & Wurm, F. R.https://doi.org/10.1016/j.actbio.2020.09.016Controlling the biodegradation rates of poly(globalide-co-ε-caprolactone) copolymers by post polymerization modification (2020)Polymer degradation and stability, 179. Article 109287. Guindani, C., Candiotto, G., Araújo, P. H. H., Ferreira, S. R. S., de Oliveira, D., Wurm, F. R. & Landfester, K.https://doi.org/10.1016/j.polymdegradstab.2020.109287Plastics and the Environment—Current Status and Challenges in Germany and Australia (2020)Macromolecular rapid communications, 41(18). Article 2000351. Wurm, F. R., Spierling, S., Endres, H. J. & Barner, L.https://doi.org/10.1002/marc.202000351Water-soluble and degradable polyphosphorodiamidates via thiol-ene polyaddition (2020)Polymer degradation and stability, 179. Article 109224. Steinmann, M. & Wurm, F. R.https://doi.org/10.1016/j.polymdegradstab.2020.109224Intrinsic flame retardant phosphonate-based vitrimers as a recyclable alternative for commodity polymers in composite materials (2020)Polymer chemistry, 11(30), 4933-4941. Markwart, J. C., Battig, A., Urbaniak, T., Haag, K., Koschek, K., Schartel, B. & Wurm, F. R.https://doi.org/10.1039/D0PY00275EOne-Step Ring Opening Metathesis Block-Like Copolymers and their Compositional Analysis by a Novel Retardation Technique (2020)Angewandte Chemie (international edition), 59(32), 13597-13601. Yasir, M., Liu, P., Markwart, J. C., Suraeva, O., Wurm, F. R., Smart, J., Lattuada, M. & Kilbinger, A. F. M.https://doi.org/10.1002/anie.202005366One‐Step Ring Opening Metathesis Block‐Like Copolymers and their Compositional Analysis by a Novel Retardation Technique (2020)Angewandte Chemie, 132(32), 13699-13703. Yasir, M., Liu, P., Markwart, J. C., Suraeva, O., Wurm, F. R., Smart, J., Lattuada, M. & Kilbinger, A. F. M.https://doi.org/10.1002/ange.202005366Membrane Engineering: Phase Separation in Polymeric Giant Vesicles (2020)Small, 16(27). Article 1905230. Rideau, E., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/smll.201905230Bio-Based Lignin Nanocarriers Loaded with Fungicides as a Versatile Platform for Drug Delivery in Plants (2020)Biomacromolecules, 21(7), 2755–2763. Machado, T. O., Beckers, S. J., Fischer, J., Müller, B., Sayer, C., Araújo, P. H. H. d., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/acs.biomac.0c00487Mimic of the Cellular Antioxidant Defense System for a Sustainable Regeneration of Nicotinamide Adenine Dinucleotide (NAD) (2020)ACS Applied Materials and Interfaces, 12(23), 25625–25632. Jo, S.-M., Zhang, K. A. I., Wurm, F. R. & Landfester, K.https://doi.org/10.1021/acsami.0c05588Biodegradable, lignin-based encapsulation enables delivery of Trichoderma reesei with programmed enzymatic release against grapevine trunk diseases (2020)Materials Today Bio, 7. Article 100061. Peil, S., Beckers, S. J., Fischer, J. & Wurm, F. R.https://doi.org/10.1016/j.mtbio.2020.100061Insight into Protein–Polymer Conjugate Relaxation Dynamics: The Importance of Polymer Grafting (2020)Macromolecular bioscience, 20(6). Article 1900410. Russo, D., Pelosi, C., Wurm, F. R., Frick, B., Ollivier, J. & Teixeira, J.https://doi.org/10.1002/mabi.201900410Nonionic surfactants based on amphiphilic polyphosphonate copolymers prepared via anionic ring-opening copolymerization (2020)European polymer journal, 131. Article 109700. Rheinberger, T., Wolf, T. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2020.109700Controlling the crystal structure of precisely spaced polyethylene-like polyphosphoesters (2020)Polymer chemistry, 11(20), 3404-3415. Haider, T., Suraeva, O., O'Duill, M. L., Mars, J., Mezger, M., Lieberwirth, I. & Wurm, F. R.https://doi.org/10.1039/D0PY00272KVitamin C Loaded Polyethylene: Synthesis and Properties of Precise Polyethylene with Vitamin C Defects via Acyclic Diene Metathesis Polycondensation (2020)Macromolecules, 53(8), 2932–2941. Suraeva, O., Champanhac, C., Mailänder, V., Wurm, F. R., Weiss, H., Berger, R., Mezger, M., Landfester, K. & Lieberwirth, I.https://doi.org/10.1021/acs.macromol.0c00086Clean synthesis of linear and star amphiphilic poly(ε-caprolactone)-block-poly(ethyl ethylene phosphonate) block copolymers: assessing self-assembly and surface activity (2020)Green chemistry, 22(10), 3248-3261. Baheti, P., Rheinberger, T., Gimello, O., Bouilhac, C., Wurm, F. R., Lacroix-Desmazes, P. & Howdle, S. M.https://doi.org/10.1039/D0GC00819BDie PET-Mineralwasserflasche: Wasser in Plastik, Plastik in Wasser (2020)Chemie in Unserer Zeit, 54(1), 14-20. Sattlegger, L., Haider, T., Völker, C., Kerber, H., Kramm, J., Zimmermann, L. & Wurm, F. R.https://doi.org/10.1002/ciuz.201900875Linear Well-Defined Polyamines via Anionic Ring-Opening Polymerization of Activated Aziridines: From Mild Desulfonylation to Cell Transfection (2020)ACS macro letters, 9(1), 20-25. Gleede, T., Yu, F., Luo, Y.-L., Yuan, Y. & Wurm, F. R.https://doi.org/10.1021/acsmacrolett.9b00792Hydrophilic polyphosphoester-conjugated fluorinated chlorin as an entirely biodegradable nano-photosensitizer for reliable and efficient photodynamic therapy (2020)Chemical communications, 56(16), 2415-2418. Liu, Z., Wu, M., Xue, Y., Chen, C., Wurm, F. R., Lan, M. & Zhang, W.https://doi.org/10.1039/D0CC00142BOncolytic Nanoreactors Producing Hydrogen Peroxide for Oxidative Cancer Therapy (2020)Nano letters, 20(1), 526–533. Jo, S.-M., Wurm, F. R. & Landfester, K.https://doi.org/10.1021/acs.nanolett.9b04263Seawater-Degradable Polymers—Fighting the Marine Plastic Pollution (2020)Advanced science, 8(1). Article 2001121. Wang, G. X., Huang, D., Ji, J. H., Völker, C. & Wurm, F. R.https://doi.org/10.1002/advs.202001121Seawater‐Degradable Polymers: Seawater‐Degradable Polymers—Fighting the Marine Plastic Pollution (Adv. Sci. 1/2021) (2020)Advanced science. Article 2170004. Wang, G., Huang, D., Ji, J., Völker, C. & Wurm, F. R.https://doi.org/10.1002/advs.202170004Sulfur's role in the flame retardancy of thio-ether–linked hyperbranched polyphosphoesters in epoxy resins (2020)European polymer journal, 122. Article 109390. Battig, A., Markwart, J. C., Wurm, F. R. & Schartel, B.https://doi.org/10.1016/j.eurpolymj.2019.109390

2019

Thermo-responsive polymer brushes with side graft chains: Relationship between molecular architecture and underwater adherence (2019)International journal of molecular sciences, 20(24). Article 6295. Sidoli, U., Tee, H. T., Raguzin, I., Mühldorfer, J., Wurm, F. R. & Synytska, A.https://doi.org/10.3390/ijms20246295Competitive Copolymerization: Access to Aziridine Copolymers with Adjustable Gradient Strengths (2019)Macromolecules, 52(24), 9703–9714. Gleede, T., Markwart, J. C., Huber, N., Rieger, E. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.9b01623Matrix matters: Hyperbranched flame retardants in aliphatic and aromatic epoxy resins (2019)Polymer degradation and stability, 170. Article 108986. Battig, A., Markwart, J. C., Wurm, F. R. & Schartel, B.https://doi.org/10.1016/j.polymdegradstab.2019.108986Noncovalent Targeting of Nanocarriers to Immune Cells with Polyphosphoester‐Based Surfactants in Human Blood Plasma (2019)Advanced science, 6(22). Article 1901199. Simon, J., Bauer, K. N., Langhanki, J., Opatz, T., Mailänder, V., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/advs.201901199Both Poly(ethylene glycol) and Poly(methyl ethylene phosphate) Guide Oriented Adsorption of Specific Proteins (2019)Langmuir, 35(43), 14092–14097. Bernhard, C., Roeters, S. J., Bauer, K. N., Weidner, T., Bonn, M., Wurm, F. R. & Gonella, G.https://doi.org/10.1021/acs.langmuir.9b02275Polymer-Based Module for NAD+ Regeneration with Visible Light (2019)ChemBioChem, 20(20), 2593-2596. Ma, B. C., Caire da Silva, L., Jo, S.-M., Wurm, F. R., Bannwarth, M. B., Zhang, K. A. I., Sundmacher, K. & Landfester, K.https://doi.org/10.1002/cbic.201900093Covalently Binding of Bovine Serum Albumin to Unsaturated Poly(Globalide-Co-ε-Caprolactone) Nanoparticles by Thiol-Ene Reactions (2019)Macromolecular bioscience, 19(10). Article 1900145. Guindani, C., Frey, M.-L., Simon, J., Koynov, K., Schultze, J., Ferreira, S. R. S., Araújo, P. H. H., de Oliveira, D., Wurm, F. R., Mailänder, V. & Landfester, K.https://doi.org/10.1002/mabi.201900145Self‐Assembly of Giant Unilamellar Vesicles by Film Hydration Methodologies (2019)Advanced Biology, 3(6). Article 1800324. Rideau, E., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/adbi.201800324Noncovalent Hydrogen Bonds Tune the Mechanical Properties of Phosphoester Polyethylene Mimics (2019)ACS Omega, 4(5), 9324-9332. Tee, H. T., Koynov, K., Reichel, T. & Wurm, F. R.https://doi.org/10.1021/acsomega.9b01040Targeted Drug Delivery in Plants: Enzyme‐Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevine Trunk Disease Esca (2019)Advanced science, 6(15). Article 1802315. Fischer, J., Beckers, S. J., Yiamsawas, D., Thines, E., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/advs.201802315Phosphonylation Controls the Protein Corona of Multifunctional Polyglycerol‐Modified Nanocarriers (2019)Macromolecular bioscience, 19(5). Article 1800468. Danner, A., Schöttler, S., Alexandrino, E., Hammer, S., Landfester, K., Mailänder, V., Morsbach, S., Frey, H. & Wurm, F. R.https://doi.org/10.1002/mabi.201800468Effect of Polymer Chain Density on Protein–Polymer Conjugate Conformation (2019)Biomacromolecules, 20(5), 1944-1955. Russo, D., Angelis, A. d., Garvey, C. J., Wurm, F. R., Appavou, M.-S. & Prevost, S.https://doi.org/10.1021/acs.biomac.9b00184Systematically Controlled Decomposition Mechanism in Phosphorus Flame Retardants by Precise Molecular Architecture: P–O vs P–N (2019)ACS Applied Polymer Materials, 1(5), 1118-1128. Markwart, J. C., Battig, A., Zimmermann, L., Wagner, M., Fischer, J., Schartel, B. & Wurm, F. R.https://doi.org/10.1021/acsapm.9b00129From Compost to Colloids - Valorization of Spent Mushroom Substrate (2019)ACS sustainable chemistry & engineering, 7(7), 6991-6998. Beckers, S. J., Dallo, I. A., Del Campo, I., Rosenauer, C., Klein, K. & Wurm, F. R.https://doi.org/10.1021/acssuschemeng.8b06710Long-Chain Polyorthoesters as Degradable Polyethylene Mimics (2019)Macromolecules, 52(6), 2411-2420. Haider, T., Shyshov, O., Suraeva, O., Lieberwirth, I., Delius, M. v. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.9b00180Nanoscopic hydrophilic/hydrophilic phase-separation well below the LCST of polyphosphoesters (2019)Chemical communications, 55(23), 3414-3417. Hunold, J., Wolf, T., Wurm, F. R. & Hinderberger, D.https://doi.org/10.1039/C8CC09788GProtein–Polymer Dynamics as Affected by Polymer Coating and Interactions (2019)Langmuir, 35(7), 2674-2679. Russo, D., Angelis, A. D., Paciaroni, A., Frick, B., Sousa, N. d., Wurm, F. R. & Teixeira, J.https://doi.org/10.1021/acs.langmuir.8b03636Aliphatic Long-Chain Polypyrophosphates as Biodegradable Polyethylene Mimics (2019)Macromolecules, 52(3), 1166–1172. Tee, H. T., Lieberwirth, I. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.8b02474Copolymerization of Cyclic Phosphonate and Lactide: Synthetic Strategies toward Control of Amphiphilic Microstructure (2019)Macromolecules, 52(3), 1220-1226. Beament, J., Wolf, T., Markwart, J. C., Wurm, F. R., Jones, M. D. & Buchard, A.https://doi.org/10.1021/acs.macromol.8b02385Ligand-Binding Cooperativity Effects in Polymer–Protein Conjugation (2019)Biomacromolecules, 20(2), 1118-1131. Reichenwallner, J., Thomas, A., Steinbach, T., Eisermann, J., Schmelzer, C. E. H., Wurm, F. & Hinderberger, D.https://doi.org/10.1021/acs.biomac.9b00016Interfacial Conformation of Hydrophilic Polyphosphoesters Affects Blood Protein Adsorption (2019)ACS Applied Materials and Interfaces, 11(1), 1624-1629. Bernhard, C., Bauer, K. N., Bonn, M., Wurm, F. R. & Gonella, G.https://doi.org/10.1021/acsami.8b17146Supercooled Water Drops Do Not Freeze During Impact on Hybrid Janus Particle-Based Surfaces (2019)Chemistry of materials, 31(1), 112-123. Schwarzer, M., Otto, T., Schremb, M., Marschelke, C., Tee, H. T., Wurm, F. R., Roisman, I. V., Tropea, C. & Synytska, A.https://doi.org/10.1021/acs.chemmater.8b03183Kunststoffe der Zukunft? Der Einfluss von bioabbaubaren Polymeren auf Umwelt und Gesellschaft (2019)Angewandte Chemie, 131(1), 50-63. Haider, T. P., Völker, C., Kramm, J., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/ange.201805766Plastics of the Future? The Impact of Biodegradable Polymers on the Environment and on Society (2019)Angewandte Chemie (international edition), 58(1), 50-62. Haider, T. P., Völker, C., Kramm, J., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/anie.201805766Aromatic vs. aliphatic hyperbranched polyphosphoesters as flame retardants in epoxy resins (2019)Molecules, 24(21). Article 3901. Markwart, J. C., Battig, A., Velencoso, M. M., Pollok, D., Schartel, B. & Wurm, F. R.https://doi.org/10.3390/molecules24213901Aziridines and azetidines: Building blocks for polyamines by anionic and cationic ring-opening polymerization (2019)Polymer chemistry, 10, 3257-3283. Gleede, T., Reisman, L., Rieger, E., Mbarushimana, P. C., Rupar, P. A. & Wurm, F. R.https://doi.org/10.1039/c9py00278bCorrection: Hyperbranched phosphorus flame retardants: multifunctional additives for epoxy resins (Polymer Chemistry (2019) DOI: 10.1039/c9py00737g) (2019)Polymer chemistry, 10, 4621-4622. Battig, A., Markwart, J. C., Wurm, F. R. & Schartel, B.https://doi.org/10.1039/c9py90116gFirst phosphorus AB2 monomer for flame-retardant hyperbranched polyphosphoesters: AB2 Vs. A2 + B3 (2019)Polymer chemistry, 10(43), 5920-5930 . Markwart, J. C., Battig, A., Kuckhoff, T., Schartel, B. & Wurm, F. R.https://doi.org/10.1039/C9PY01156KHyperbranched phosphorus flame retardants: Multifunctional additives for epoxy resins (2019)Polymer chemistry, 10(31), 4346-4358. Battig, A., Markwart, J. C., Wurm, F. R. & Schartel, B.https://doi.org/10.1039/c9py00737gMagnetoliposomes with size controllable insertion of magnetic nanoparticles for efficient targeting of cancer cells (2019)RSC advances, 9(26), 15053-15060. Choi, W. I., Sahu, A., Wurm, F. R. & Jo, S.-M.https://doi.org/10.1039/C9RA02529DOrganocatalytic Ring-opening Polymerization Towards Poly(cyclopropane)s, Poly(lactame)s, Poly(aziridine)s, Poly(siloxane)s, Poly(carbosiloxane)s, Poly(phosphate)s, Poly(phosphonate)s, Poly(thiolactone)s, Poly(thionolactone)s and Poly(thiirane)s (2019)In Organic catalysis for polymerisation. Wolf, T. & Wurm, F. R.https://doi.org/10.1039/9781788015738-00406Thermodynamic stability of myoglobin-poly(ethylene glycol) bioconjugates: A calorimetric study (2019)Thermochimica acta, 671, 26-31. Pelosi, C., Saitta, F., Wurm, F. R., Fessas, D., Tinè, M. R. & Duce, C.https://doi.org/10.1016/j.tca.2018.11.001

2018

The 2-acetylthioethyl ester group: A versatile protective group for P-OH-groups (2018)Tetrahedron, 74(52), 7426-7430. Markwart, J. C. & Wurm, F. R.https://doi.org/10.1016/j.tet.2018.11.002The 7th Sino–German Frontiers of Chemistry Symposium – Learning from Nature (2018)Chemistry: an Asian journal, 13(23), 3556-3560. Jiang, W. & Wurm, F. R.https://doi.org/10.1002/asia.201801593Protein Corona Mediated Stealth Properties of Biocompatible Carbohydrate-based Nanocarriers (2018)Israel journal of chemistry, 58(12), 1363-1372. Simon, J., Christmann, S., Mailänder, V., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/ijch.201800166Mechanistic study on the hydrolytic degradation of polyphosphates (2018)European polymer journal, 108, 286-294. Bauer, K. N., Wagner, M., Andrienko, D. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2018.08.058PPEylation of proteins: Synthesis, activity, and stability of myoglobin-polyphosphoester conjugates (2018)European polymer journal, 108, 357-363. Pelosi, C., Duce, C., Russo, D., Tiné, M. R. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2018.09.019Fast Access to Amphiphilic Multiblock Architectures by the Anionic Copolymerization of Aziridines and Ethylene Oxide (2018)Journal of the American Chemical Society, 140(41), 13407-13412. Gleede, T., Rieger, E., Blankenburg, J., Klein, K. & Wurm, F. R.https://doi.org/10.1021/jacs.8b08054Biomimetic Cascade Network between Interactive Multicompartments Organized by Enzyme-Loaded Silica Nanoreactors (2018)ACS Applied Materials and Interfaces, 10(40), 34230-34237. Jo, S.-M., Wurm, F. R. & Landfester, K.https://doi.org/10.1021/acsami.8b11198Alcohol- and Water-Tolerant Living Anionic Polymerization of Aziridines (2018)Macromolecules, 51(15), 5713-5719. Gleede, T., Rieger, E., Liu, L., Bakkali-Hassani, C., Wagner, M., Carlotti, S., Taton, D., Andrienko, D. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.8b01320Molecular Firefighting—How Modern Phosphorus Chemistry Can Help Solve the Challenge of Flame Retardancy (2018)Angewandte Chemie (international edition), 57(33), 10450-10467. Velencoso, M. M., Battig, A., Markwart, J. C., Schartel, B. & Wurm, F. R.https://doi.org/10.1002/anie.201711735Molekulare Brandbekämpfung – wie moderne Phosphorchemie zur Lösung der Flammschutzaufgabe beitragen kann (2018)Angewandte Chemie, 130(33), 10608-10626. Velencoso, M. M., Battig, A., Markwart, J. C., Schartel, B. & Wurm, F. R.https://doi.org/10.1002/ange.201711735Microwave-Assisted Desulfonylation of Polysulfonamides toward Polypropylenimine (2018)ACS macro letters, 7(6), 598-603. Rieger, E., Gleede, T., Manhart, A., Lamla, M. & Wurm, F. R.https://doi.org/10.1021/acsmacrolett.8b00180Hydrophilicity Regulates the Stealth Properties of Polyphosphoester-Coated Nanocarriers (2018)Angewandte Chemie (international edition), 57(19), 5548-5553. Simon, J., Wolf, T., Klein, K., Landfester, K., Wurm, F. R. & Mailänder, V.https://doi.org/10.1002/anie.201800272Hydrophilie als bestimmender Faktor des Stealth-Effekts von Polyphosphoester-funktionalisierten Nanoträgern (2018)Angewandte Chemie, 130(19), 5647-5653. Simon, J., Wolf, T., Klein, K., Landfester, K., Wurm, F. R. & Mailänder, V.https://doi.org/10.1002/ange.201800272Selective Initiation from Unprotected Aminoalcohols for the N -Heterocyclic Carbene-Organocatalyzed Ring-Opening Polymerization of 2-Methyl- N- tosyl Aziridine: Telechelic and Block Copolymer Synthesis (2018)Macromolecules, 51(7), 2533-2541. Bakkali-Hassani, C., Coutouly, C., Gleede, T., Vignolle, J., Wurm, F. R., Carlotti, S. & Taton, D.https://doi.org/10.1021/acs.macromol.7b02493n-Heterocyclic carbene organocatalyzed ring-opening polymerization of n-tosyl aziridines using functional initiators and amino-alcohols as bifunctional and double headed initiators (2018)Abstracts of papers of the American Chemical Society, 255. Article 813. Bakkali-Hassani, C., Vignolle, J., Carlotti, S., Taton, D., Rieger, E. & Wurm, F.Trendbericht Makromolekulare Chemie 2017: Chemie (2018)Nachrichten aus der Chemie, 66(3), 327-334. Sommer, M. & Wurm, F. R.https://doi.org/10.1002/nadc.20184071838Polymerizing Phostones: A Fast Way to In-Chain Poly(phosphonate)s with Adjustable Hydrophilicity (2018)Macromolecules, 51(4), 1272-1279. Bauer, K. N., Liu, L., Andrienko, D., Wagner, M., Macdonald, E. K., Shaver, M. P. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.7b02473Controlling the Polymer Microstructure in Anionic Polymerization by Compartmentalization (2018)Angewandte Chemie (international edition), 57(9), 2483-2487. Rieger, E., Blankenburg, J., Grune, E., Wagner, M., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/anie.201710417Kontrollierte Polymermikrostruktur in anionischer Polymerisation durch Kompartimentierung (2018)Angewandte Chemie, 130(9), 2509-2513. Rieger, E., Blankenburg, J., Grune, E., Wagner, M., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/ange.201710417Temperature responsive poly(phosphonate) copolymers: From single chains to macroscopic coacervates (2018)Polymer chemistry, 9(4), 490-498. Wolf, T., Hunold, J., Simon, J., Rosenauer, C., Hinderberger, D. & Wurm, F. R.https://doi.org/10.1039/c7py01811h4-Styrenesulfonyl-(2-methyl)aziridine: The First Bivalent Aziridine-Monomer for Anionic and Radical Polymerization (2018)Macromolecular chemistry and physics, 219(1). Article 1700145. Gleede, T., Rieger, E., Homann-Müller, T. & Wurm, F. R.https://doi.org/10.1002/macp.201700145Surface-attached poly(phosphoester)-hydrogels with benzophenone groups (2018)Polymer chemistry, 9(3), 315-326. Becker, G., Deng, Z., Zober, M., Wagner, M., Lienkamp, K. & Wurm, F. R.https://doi.org/10.1039/c7py01777dA modular approach for multifunctional polymersomes with controlled adhesive properties (2018)Soft matter, 14, 894-900. Petit, J., Thomi, L., Schultze, J., Makowski, M., Negwer, I., Koynov, K., Herminghaus, S., Wurm, F. R., Bäumchen, O. & Landfester, K.https://doi.org/10.1039/c7sm01885aBiorescue: Getting high added value products from mushroom compost (2018)In 26th European Biomass Conference and Exhibition, 14-17 May 2018, Copenhagen, Denmark (pp. 1084-1088). Del Campo, I., Alegria, I., Otazu, E., Gaffney, D., Iglesias, M., Ihalainen, P., Faraco, V., Wurm, F. R., Beckers, S., Hayes, D., Díaz-Chavez, R., Etxaniz, J., Julliard, B. & Pérez, M.Crystallization of a polyphosphoester at the air-water interface (2018)European polymer journal, 101, 350-357. Hasan, N., Schwieger, C., Tee, H. T., Wurm, F. R., Busse, K. & Kressler, J.https://doi.org/10.1016/j.eurpolymj.2018.03.001Functional biodegradable polymers via ring-opening polymerization of monomers without protective groups (2018)Chemical Society reviews, 47(20), 7739-7782. Becker, G. & Wurm, F. R.https://doi.org/10.1039/C8CS00531AGiant polymersomes from non-assisted film hydration of phosphate-based block copolymers (2018)Polymer chemistry, 9(44), 5385-5394. Rideau, E., Wurm, F. R. & Landfester, K.https://doi.org/10.1039/C8PY00992ALarge-Scale Preparation of Polymer Nanocarriers by High-Pressure Microfluidization (2018)Macromolecular materials and engineering, 303(1). Article 1700505. Shafee Alkanawati, M., Wurm, F. R., Thérien-Aubin, H. & Landfester, K.https://doi.org/10.1002/mame.201700505Liposomes and polymersomes: a comparative review towards cell mimicking (2018)Chemical Society reviews, 47(23), 8572-8610. Rideau, E., Dimova, R., Schwille, P., Wurm, F. R. & Landfester, K.https://doi.org/10.1039/C8CS00162F

2017

Multifunctional Poly(phosphoester)s for Reversible Diels–Alder Postmodification To Tune the LCST in Water (2017)Macromolecules, 50(20), 7852-7862. Becker, G., Marquetant, T. A., Wagner, M. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.7b01716Morphology-Controlled Synthesis of Lignin Nanocarriers for Drug Delivery and Carbon Materials (2017)ACS biomaterials science & engineering, 3(10), 2375-2383. Yiamsawas, D., Beckers, S. J., Lu, H., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/acsbiomaterials.7b00278Expanding the scope of N-heterocyclic carbene-organocatalyzed ring-opening polymerization of N-tosyl aziridines using functional and non-activated amine initiators (2017)European polymer journal, 95, 746-755. Bakkali-Hassani, C., Rieger, E., Vignolle, J., Wurm, F. R., Carlotti, S. & Taton, D.https://doi.org/10.1016/j.eurpolymj.2017.07.005Main-chain poly(phosphoester)s: History, syntheses, degradation, bio-and flame-retardant applications (2017)Progress in polymer science, 73, 61-122. Bauer, K. N., Tee, H. T., Velencoso, M. M. & Wurm, F. R.https://doi.org/10.1016/j.progpolymsci.2017.05.004Polyglycerol Surfmers and Surfactants for Direct and Inverse Miniemulsion (2017)Macromolecular bioscience, 17(10). Article 1700070. Wald, S., Simon, J., Dietz, J. P., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/mabi.201700070Reversible Bioconjugation: Biodegradable Poly(phosphate)-Protein Conjugates (2017)Macromolecular bioscience, 17(10). Article 1600377. Steinbach, T., Becker, G., Spiegel, A., Figueiredo, T., Russo, D. & Wurm, F. R.https://doi.org/10.1002/mabi.201600377Thermoresponsive coacervate formation of random poly(phosphonate) terpolymers (2017)European polymer journal, 95, 756-765. Wolf, T., Rheinberger, T. & Wurm, F. R.https://doi.org/10.1016/j.eurpolymj.2017.05.048Acid-labile surfactants based on poly(ethyleneglycol), carbon dioxide and propylene oxide: Miniemulsion polymerization and degradation studies (2017)Polymers, 9(9). Article 422. Scharfenberg, M., Wald, S., Wurm, F. R. & Frey, H.https://doi.org/10.3390/polym9090422Fully degradable protein nanocarriers by orthogonal photoclick tetrazole-ene chemistry for the encapsulation and release (2017)Nanoscale Horizons, 2(5), 297-302. Piradashvili, K., Simon, J., Paßlick, D., Höhner, J. R., Mailänder, V., Wurm, F. R. & Landfester, K.https://doi.org/10.1039/c7nh00062fRuthenocenyl Glycidyl Ether: A Ruthenium-Containing Epoxide for Anionic Polymerization (2017)Organometallics, 36(16), 3023–3028. Alkan, A., Gleede, T. & Wurm, F. R.https://doi.org/10.1021/acs.organomet.7b00278Reversible Self-Assembly of Degradable Polymersomes with Upper Critical Solution Temperature in Water (2017)Journal of the American Chemical Society, 139(32), 11064-11072. Wolf, T., Rheinberger, T., Simon, J. & Wurm, F. R.https://doi.org/10.1021/jacs.7b02723Triazolinedione-"clicked" poly(phosphoester)s: Systematic adjustment of thermal properties (2017)Polymer chemistry, 8(28), 4074-4078. Becker, G., Vlaminck, L., Velencoso, M. M., Du Prez, F. E. & Wurm, F. R.https://doi.org/10.1039/c7py00813aPolyphosphoesters: An Old Biopolymer in a New Light (2017)In Polymers for Biomedicine: Synthesis, Characterization, and Applications (pp. 191-242). Wiley. Bauer, K. N., Tee, H. T. C., Alexandrino, E. M. & Wurm, F. R.https://doi.org/10.1002/9781118967904.ch7Breathing air as oxidant: Optimization of 2-chloro-2-oxo-1,3,2-dioxaphospholane synthesis as a precursor for phosphoryl choline derivatives and cyclic phosphate monomers (2017)Tetrahedron, 73(25), 3536-3540. Becker, G. & Wurm, F. R.https://doi.org/10.1016/j.tet.2017.05.037Biorescue: Enhanced bioconversion of agricultural residues through cascading use (2017)In Proceedings - EUBCE 2017 (pp. 2015-2018). Del Campo, I., Alegria, I., Otazu, E., Gaffney, D., Forde, C., Ihalainen, P., Faraco, V., Wurm, F., Hayes, D., Díaz-Chavez, R., Etxaniz, J., Julliard, B., Pérez, M. & Sanciñena, J.The living anionic polymerization of activated aziridines: A systematic study of reaction conditions and kinetics (2017)Polymer chemistry, 8(18), 2824-2832. Rieger, E., Gleede, T., Weber, K., Manhart, A., Wagner, M. & Wurm, F. R.https://doi.org/10.1039/c7py00436bPoly(alkyl ethylene phosphonate)s: A New Class of Non-amide Kinetic Hydrate Inhibitor Polymers (2017)Energy & fuels, 31(4), 3843-3848. Lin, H., Wolf, T., Wurm, F. R. & Kelland, M. A.https://doi.org/10.1021/acs.energyfuels.7b00019Site-Specific Polymer Attachment to HR2 Peptide Fusion Inhibitors against HIV-1 Decreases Binding Association Rates and Dissociation Rates Rather Than Binding Affinity (2017)Bioconjugate chemistry, 28(3), 701-712. Danial, M., Stauffer, A. N., Wurm, F. R., Root, M. J. & Klok, H. A.https://doi.org/10.1021/acs.bioconjchem.6b00540Joining Two Natural Motifs: Catechol-Containing Poly(phosphoester)s (2017)Biomacromolecules, 18(3), 767-777. Becker, G., Ackermann, L. M., Schechtel, E., Klapper, M., Tremel, W. & Wurm, F. R.https://doi.org/10.1021/acs.biomac.6b01613Makromolekulare Chemie 2016 (2017)Nachrichten aus der Chemie, 65(3), 348-358. Sommer, M. & Wurm, F.https://doi.org/10.1002/nadc.20174057501Amphiphilic Ferrocene-Containing PEG Block Copolymers as Micellar Nanocarriers and Smart Surfactants (2017)Langmuir, 33(1), 272-279. Alkan, A., Wald, S., Louage, B., De Geest, B. G., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/acs.langmuir.6b03917Functional Colloidal Stabilization (2017)Advanced materials interfaces, 4(1). Article 1600443. Bijlard, A. C., Wald, S., Crespy, D., Taden, A., Wurm, F. R. & Landfester, K.https://doi.org/10.1002/admi.201600443Coating nanoparticles with tunable surfactants facilitates control over the protein corona (2017)Biomaterials, 115, 1-8. Müller, J., Bauer, K. N., Prozeller, D., Simon, J., Mailänder, V., Wurm, F. R., Winzen, S. & Landfester, K.https://doi.org/10.1016/j.biomaterials.2016.11.015

2016

Binding Matters: Binding Patterns Control the Degradation of Phosphorus-containing Polymers (2016)Green Materials, 4(4), 135-139. Wurm, F. R.https://doi.org/10.1680/jgrma.16.00016Poly(phosphorodiamidate)s by Olefin Metathesis Polymerization with Precise Degradation (2016)Chemistry : a European journal, 22(48), 17329-17338. Steinmann, M., Wagner, M. & Wurm, F. R.https://doi.org/10.1002/chem.201603990MPLA-coated hepatitis B virus surface antigen (HBsAg) nanocapsules induce vigorous T cell responses in cord blood derived human T cells (2016)Nanomedicine : nanotechnology, biology and medicine, 12(8), 2383-2394. Pietrzak-Nguyen, A., Piradashvili, K., Fichter, M., Pretsch, L., Zepp, F., Wurm, F. R., Landfester, K. & Gehring, S.https://doi.org/10.1016/j.nano.2016.07.010Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses (2016)Biomaterials, 108, 1-12. Fichter, M., Piradashvili, K., Pietrzak-Nguyen, A., Pretsch, L., Kuhn, G., Strand, S., Knuf, M., Zepp, F., Wurm, F. R., Mailänder, V., Landfester, K. & Gehring, S.https://doi.org/10.1016/j.biomaterials.2016.08.046Fast ultrasound assisted synthesis of chitosan-based magnetite nanocomposites as a modified electrode sensor (2016)Carbohydrate polymers, 151, 760-769. Freire, T. M., Dutra, L. M. U., Queiroz, D. C., Ricardo, N. M. P. S., Barreto, K., Denardin, J. C., Wurm, F. R., Sousa, C. P., Correia, A. N., De Lima-Neto, P. & Fechine, P. B. A.https://doi.org/10.1016/j.carbpol.2016.05.095Degradable Polyphosphoester-Protein Conjugates: "PPEylation" of Proteins (2016)Biomacromolecules, 17(10), 3338-3346. Steinbach, T. & Wurm, F. R.https://doi.org/10.1021/acs.biomac.6b01107ALTMET polymerization of amino acid-based monomers targeting controlled drug release (2016)Macromolecules, 49(18), 6723-6730. Peres, L. B., Preiss, L. C., Wagner, M., Wurm, F. R., De Araújo, P. H. H., Landfester, K., Muñoz-Espí, R. & Sayer, C.https://doi.org/10.1021/acs.macromol.6b01530N -Ferrocenylsulfonyl-2-methylaziridine: The first ferrocene monomer for the anionic (co)polymerization of aziridines (2016)Polymer chemistry, 7(35), 5501-5506. Homann-Müller, T., Rieger, E., Alkan, A. & Wurm, F. R.https://doi.org/10.1039/c6py01019aPoly(phosphoester) Colloids by Interfacial Polycondensation in Miniemulsion (2016)Macromolecular chemistry and physics, 217(17), 1941-1947. Alexandrino, E. M., Wagner, M., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/macp.201600218Water-Soluble Metallocene-Containing Polymers (2016)Macromolecular rapid communications, 37(18), 1482-1493. Alkan, A. & Wurm, F. R.https://doi.org/10.1002/marc.201600205Side-chain poly(phosphoramidate)s: Via acyclic diene metathesis polycondensation (2016)Polymer chemistry, 7(31), 5004-5010. Cankaya, A., Steinmann, M., Bülbül, Y., Lieberwirth, I. & Wurm, F. R.https://doi.org/10.1039/c6py00999aStabilization of inverse miniemulsions by silyl-protected homopolymers (2016)Polymers, 8(8). Article 303. Wald, S., Wurm, F. R., Landfester, K. & Crespy, D.https://doi.org/10.3390/polym8080303Artificial cartilage bio-matrix formed of hyaluronic acid and MG2+-polyphosphate (2016)European cells & materials, 32, 271-283. Wang, X., Ackermann, M., Tolba, E., Neufurth, M., Wurm, F., Feng, Q., Schröder, H. C. & Müller, W. E. G.https://doi.org/10.22203/ECM.V032A18In-chain poly(phosphonate)s via acyclic diene metathesis polycondensation (2016)Macromolecules, 49(10), 3761-3768. Bauer, K. N., Tee, H. T., Lieberwirth, I. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.6b00366Cyclohexyl-substituted poly(phosphonate)-copolymers with adjustable glass transition temperatures (2016)Polymer chemistry, 7(17), 2934-2937. Wolf, T., Naß, J. & Wurm, F. R.https://doi.org/10.1039/c6py00358cAcid-Labile Amphiphilic PEO-b-PPO-b-PEO Copolymers: Degradable Poloxamer Analogs (2016)Macromolecular rapid communications, 37(9), 775-780. Worm, M., Kang, B., Dingels, C., Wurm, F. R. & Frey, H.https://doi.org/10.1002/marc.201600080Sequence-Controlled Polymers via Simultaneous Living Anionic Copolymerization of Competing Monomers (2016)Macromolecular rapid communications, 37(10), 833-839. Rieger, E., Alkan, A., Manhart, A., Wagner, M. & Wurm, F. R.https://doi.org/10.1002/marc.201600092Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers (2016)Nature nanotechnology, 11(4), 372-377. Schöttler, S., Becker, G., Winzen, S., Steinbach, T., Mohr, K., Landfester, K., Mailänder, V. & Wurm, F. R.https://doi.org/10.1038/nnano.2015.330Morphology and Thermal Properties of Precision Polymers: The Crystallization of Butyl Branched Polyethylene and Polyphosphoesters (2016)Macromolecules, 49(4), 1321-1330. Zheng, Y. R., Tee, H. T., Wei, Y., Wu, X. L., Mezger, M., Yan, S., Landfester, K., Wagener, K., Wurm, F. R. & Lieberwirth, I.https://doi.org/10.1021/acs.macromol.5b02581Hydroxyethyl starch nanocapsules as a potent drug-delivery system for targeting of CD4+CD25+T cells with different IL-2 receptor affinities (2016)Experimental dermatology, 25(3), E24. Article P140. Domogalla, M. P., Frick, S. U., Baier, G., Wurm, F., Mailaender, V., Landfester, K. & Steinbrink, K.https://doi.org/10.1111/exd.12952Polymerization of ethylene oxide, propylene oxide, and other alkylene oxides: Synthesis, novel polymer architectures, and bioconjugation (2016)Chemical reviews, 116(4), 2170-2243. Herzberger, J., Niederer, K., Pohlit, H., Seiwert, J., Worm, M., Wurm, F. R. & Frey, H.https://doi.org/10.1021/acs.chemrev.5b00441Multihydroxy Polyamines by Living Anionic Polymerization of Aziridines (2016)ACS macro letters, 5(2), 195-198. Rieger, E., Manhart, A. & Wurm, F. R.https://doi.org/10.1021/acsmacrolett.5b00901Polyethers (2016)In Handbook of Thermoplastics: Second Edition (pp. 251-284). CRC Press/Balkema. Klein, R. & Wurm, F. R.Stimulus-Responsive Release from Poly(ferrocenylsilane) Nanocontainers (2016)Macromolecules, 49(1), 105-109. Thomi, L., Schaefer, P., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.5b02367Investigation into the Relaxation Dynamics of Polymer-Protein Conjugates Reveals Surprising Role of Polymer Solvation on Inherent Protein Flexibility (2016)Biomacromolecules, 17(1), 141-147. Russo, D., Plazanet, M., Teixeira, J., Moulin, M., Härtlein, M., Wurm, F. R. & Steinbach, T.https://doi.org/10.1021/acs.biomac.5b01269Processing and adjusting the hydrophilicity of poly(oxymethylene) (co)polymers: Nanoparticle preparation and film formation (2016)Polymer chemistry, 7(1), 184-190. Bannwarth, M. B., Klein, R., Kurch, S., Frey, H., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c5py01418bCompeting and simultaneous click reactions at the interface and in solution (2016)RSC advances, 6(56), 51327-51331. Yiamsawas, D., Wagner, M., Baier, G., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c6ra08880eHigh biocompatibility and improved osteogenic potential of amorphous calcium carbonate/vaterite (2016)Journal of materials chemistry. B: materials for biology and medicine, 4(3), 376-386. Tolba, E., Müller, W. E. G., Abd El-Hady, B. M., Neufurth, M., Wurm, F., Wang, S., Schröder, H. C. & Wang, X.https://doi.org/10.1039/c5tb02228bInterleukin-2 Functionalized Nanocapsules for T Cell-Based lmmunotherapy (2016)ACS nano, 10(10), 9216-9226. Frick, S. U., Domogalla, M. P., Baier, G., Wurm, F. R., Mailaender, V., Landfester, K. & Steinbrink, K.https://doi.org/10.1021/acsnano.5b07973Reactions and polymerizations at the liquid-liquid interface (2016)Chemical reviews, 116(4), 2141-2169. Piradashvili, K., Alexandrino, E. M., Wurm, F. R. & Landfester, K.https://doi.org/10.1021/acs.chemrev.5b00567The organocatalytic ring-opening polymerization of N -tosyl aziridines by an N-heterocyclic carbene (2016)Chemical communications, 52(62), 9719-9722. Bakkali-Hassani, C., Rieger, E., Vignolle, J., Wurm, F. R., Carlotti, S. & Taton, D.https://doi.org/10.1039/c6cc04323b

2015

Triple-Stimuli-Responsive Ferrocene-Containing PEGs in Water and on the Surface (2015)ACS Applied Materials and Interfaces, 7(47), 26137-26144. Alkan, A., Steinmetz, C., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/acsami.5b07945Carbohydrate nanocarriers in biomedical applications: Functionalization and construction (2015)Chemical Society reviews, 44(22), 8301-8325. Kang, B., Opatz, T., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c5cs00092kWater-soluble and redox-responsive hyperbranched polyether copolymers based on ferrocenyl glycidyl ether (2015)Polymer chemistry, 6(40), 7112-7118. Alkan, A., Klein, R., Shylin, S. I., Kemmer-Jonas, U., Frey, H. & Wurm, F. R.https://doi.org/10.1039/c5py01162kReactive poly(phosphoester)-telechelics (2015)Journal of Polymer Research, 22(7). Article 143. Steinmann, M., Marsico, F. & Wurm, F. R.https://doi.org/10.1007/s10965-015-0788-1A Library of Well-Defined and Water-Soluble Poly(alkyl phosphonate)s with Adjustable Hydrolysis (2015)Macromolecules, 48(12), 3853-3863. Wolf, T., Steinbach, T. & Wurm, F. R.https://doi.org/10.1021/acs.macromol.5b00897Kohlenhydrat-basierte Nanocarrier mit spezifischem Zell-Targeting und minimalem Einfluss durch die Proteinkorona (2015)Angewandte Chemie, 127(25), 7544-7548. Kang, B., Okwieka, P., Schöttler, S., Winzen, S., Langhanki, J., Mohr, K., Opatz, T., Mailänder, V., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/ange.201502398Aliphatic polyethers: Classical polymers for the 21st century (2015)Macromolecular rapid communications, 36(12), 1147-1165. Klein, R. & Wurm, F. R.https://doi.org/10.1002/marc.201500013Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona (2015)Angewandte Chemie (international edition), 54(25), 7436-7440. Kang, B., Okwieka, P., Schöttler, S., Winzen, S., Langhanki, J., Mohr, K., Opatz, T., Mailänder, V., Landfester, K. & Wurm, F. R.https://doi.org/10.1002/anie.201502398Vinyl ferrocenyl glycidyl ether: An unprotected orthogonal ferrocene monomer for anionic and radical polymerization (2015)Polymer chemistry, 6(19), 3617-3624. Alkan, A., Thomi, L., Gleede, T. & Wurm, F. R.https://doi.org/10.1039/c5py00404gPoly(phosphoester)s: A New Platform for Degradable Polymers (2015)Angewandte Chemie (international edition), 54(21), 6098-6108. Steinbach, T. & Wurm, F. R.https://doi.org/10.1002/anie.201500147Polyphosphoester: eine neue Plattform für abbaubare Polymere (2015)Angewandte Chemie, 127(21), 6196-6207. Steinbach, T. & Wurm, F. R.https://doi.org/10.1002/ange.201500147Tailoring the stealth properties of biocompatible polysaccharide nanocontainers (2015)Biomaterials, 49, 125-134. Kang, B., Okwieka, P., Schöttler, S., Seifert, O., Kontermann, R. E., Pfizenmaier, K., Musyanovych, A., Meyer, R., Diken, M., Sahin, U., Mailänder, V., Wurm, F. R. & Landfester, K.https://doi.org/10.1016/j.biomaterials.2015.01.042Biodegradable Protein Nanocontainers (2015)Biomacromolecules, 16(3), 815-821. Piradashvili, K., Fichter, M., Mohr, K., Gehring, S., Wurm, F. R. & Landfester, K.https://doi.org/10.1021/bm5016915Living anionic polymerization of functional aziridines (2015)Macromolecular symposia, 349(1), 51-56. Thomi, L. & Wurm, F. R.https://doi.org/10.1002/masy.201400006Poly(phosphonate)-mediated Horner-Wadsworth-Emmons reactions (2015)Polymer chemistry, 6(7), 1192-1202. Steinbach, T., Wahlen, C. & Wurm, F. R.https://doi.org/10.1039/c4py01365dSophorolipids: Expanding structural diversity by ring-opening cross-metathesis (2015)European Journal of Lipid Science and Technology, 117(2), 217-228. Peng, Y., Totsingan, F., Meier, M. A. R., Steinmann, M., Wurm, F., Koh, A. & Gross, R. A.https://doi.org/10.1002/ejlt.201400466Multifunctional poly(phosphoester)s with two orthogonal protective groups (2015)RSC advances, 5(53), 42881-42888. Müller, L. K., Steinbach, T. & Wurm, F. R.https://doi.org/10.1039/c5ra07167dPolyacrylonitrile (2015)In Handbook of Thermoplastics. CRC Press (Taylor & Francis). Klein, R. & Wurm, F.https://doi.org/10.1201/b19190-8

2014

Poly(alkylidene chlorophosphate)s via acyclic diene metathesis polymerization: A general platform for the postpolymerization modification of poly(phosphoester)s (2014)Macromolecules, 47(24), 8506-8513. Steinmann, M., Markwart, J. & Wurm, F. R.https://doi.org/10.1021/ma501959hHyperbranched poly(phosphoester)s as flame retardants for technical and high performance polymers (2014)Polymer chemistry, 5(24), 7042-7053. Täuber, K., Marsico, F., Wurm, F. R. & Schartel, B.https://doi.org/10.1039/c4py00830hA molecular “screw-clamp”: Accelerating click reactions in miniemulsions (2014)Chemical communications, 50(72), 10495-10498. Alexandrino, E. M., Wagner, M., Fuchs, A., Kreyes, A., Weiss, C. K., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c4cc04119dPoly(phosphonate)s via olefin metathesis: Adjusting hydrophobicity and morphology (2014)Macromolecules, 47(15), 4884-4893. Steinbach, T., Alexandrino, E. M., Wahlen, C., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/ma5013286Hyperbranched unsaturated polyphosphates as a protective matrix for long-term photon upconversion in air (2014)Journal of the American Chemical Society, 136(31), 11057-11064. Marsico, F., Turshatov, A., Peköz, R., Avlasevich, Y., Wagner, M., Weber, K., Donadio, D., Landfester, K., Baluschev, S. & Wurm, F. R.https://doi.org/10.1021/ja5049412Squaric acid mediated bioconjugation expanded to polymers prepared by ATRP (2014)Polymer chemistry, 5(13), 4039-4047. Steinbach, T., Wurm, F. & Klok, H. A.https://doi.org/10.1039/c4py00168kFunctional group distribution and gradient structure resulting from the living anionic copolymerization of styrene and para -but-3-enyl styrene (2014)ACS macro letters, 3(6), 560-564. Natalello, A., Alkan, A., Von Tiedemann, P., Wurm, F. R. & Frey, H.https://doi.org/10.1021/mz500255hFerrocene-containing multifunctional polyethers: Monomer sequence monitoring via quantitative 13C NMR spectroscopy in bulk (2014)Macromolecules, 47(7), 2242-2249. Alkan, A., Natalello, A., Wagner, M., Frey, H. & Wurm, F. R.https://doi.org/10.1021/ma500323mWater-soluble poly(phosphonate)s via living ring-opening polymerization (2014)ACS macro letters, 3(3), 244-248. Steinbach, T., Ritz, S. & Wurm, F. R.https://doi.org/10.1021/mz500016hPaclitaxel-loaded polyphosphate nanoparticles: A potential strategy for bone cancer treatment (2014)Journal of materials chemistry. B: materials for biology and medicine, 2(10), 1298-1306. Alexandrino, E. M., Ritz, S., Marsico, F., Baier, G., Mailänder, V., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c3tb21295eBiodegradable lignin nanocontainers (2014)RSC advances, 4(23), 11661-11663. Yiamsawas, D., Baier, G., Thines, E., Landfester, K. & Wurm, F. R.https://doi.org/10.1039/c3ra47971dAziridine termination of living anionic polymerization (2014)Macromolecular rapid communications, 35(5), 585-589. Thomi, L. & Wurm, F. R.https://doi.org/10.1002/marc.201300860Stabilization of nanoparticles synthesized by miniemulsion polymerization using "green" amino-acid based surfactants (2014)Macromolecular symposia, 337(1), 9-17. Baier, G., Baki, A., Tomcin, S., Mailänder, V., Alexandrino, E., Wurm, F. & Landfester, K.https://doi.org/10.1002/masy.201450301Combining oxyanionic polymerization and click-chemistry: A general strategy for the synthesis of polyether polyol macromonomers (2014)Polymer chemistry, 5(3), 899-909. Thomas, A., Niederer, K., Wurm, F. & Frey, H.https://doi.org/10.1039/c3py01078cSelective interfacial olefin cross metathesis for the preparation of hollow nanocapsules (2014)ACS macro letters, 3(1), 40-43. Malzahn, K., Marsico, F., Koynov, K., Landfester, K., Weiss, C. K. & Wurm, F. R.https://doi.org/10.1021/mz400578eNanoparticles from renewable polymers (2014)Frontiers in Chemistry, 2(JUL). Article 49. Wurm, F. R. & Weiss, C. K.https://doi.org/10.3389/fchem.2014.00049

2013

Be squared: Expanding the horizon of squaric acid-mediated conjugations (2013)Chemical Society reviews, 42(21), 8220-8236. Wurm, F. R. & Klok, H. A.https://doi.org/10.1039/c3cs60153fMicrostructure analysis of biocompatible phosphoester copolymers (2013)Polymer chemistry, 4(16), 4469-4479. Steinbach, T., Schröder, R., Ritz, S. & Wurm, F. R.https://doi.org/10.1039/c3py00563aOne-pot squaric acid diester mediated aqueous protein conjugation (2013)Chemical communications, 49(71), 7815-7817. Wurm, F., Steinbach, T. & Klok, H. A.https://doi.org/10.1039/c3cc44039gA metathesis route for BODIPY labeled polyolefins (2013)Organic letters, 15(15), 3844-3847. Marsico, F., Turshatov, A., Weber, K. & Wurm, F. R.https://doi.org/10.1021/ol401461hUnsaturated poly(phosphoester)s via ring-opening metathesis polymerization (2013)Polymer chemistry, 4(13), 3800-3806. Steinbach, T., Alexandrino, E. M. & Wurm, F. R.https://doi.org/10.1039/c3py00437fFrom CO2-based multifunctional polycarbonates with a controlled number of functional groups to graft polymers (2013)Macromolecular chemistry and physics, 214(8), 892-901. Geschwind, J., Wurm, F. & Frey, H.https://doi.org/10.1002/macp.201200608Enlarging the toolbox: Epoxide termination of polyferrocenylsilane (PFS) as a key step for the synthesis of amphiphilic PFS-polyether block copolymers (2013)ACS macro letters, 2(4), 313-316. Natalello, A., Alkan, A., Friedel, A., Lieberwirth, I., Frey, H. & Wurm, F. R.https://doi.org/10.1021/mz400080sFerrocenyl glycidyl ether: A versatile ferrocene monomer for copolymerization with ethylene oxide to water-soluble, thermoresponsive copolymers (2013)Macromolecules, 46(3), 647-655. Tonhauser, C., Alkan, A., Schömer, M., Dingels, C., Ritz, S., Mailänder, V., Frey, H. & Wurm, F. R.https://doi.org/10.1021/ma302241w

2012

Squaric acid mediated chemoselective PEGylation of proteins: Reactivity of single-step-activated α-amino poly(ethylene glycol)s (2012)Chemistry : a European journal, 18(52), 16828-16835. Dingels, C., Wurm, F., Wagner, M., Klok, H. A. & Frey, H.https://doi.org/10.1002/chem.201200182Hyperbranched Polymers: Synthetic Methodology, Properties, and Complex Polymer Architectures (2012)In Polymer Science: A Comprehensive Reference, 10 Volume Set (pp. 177-198). Elsevier. Wurm, F. & Frey, H.https://doi.org/10.1016/B978-0-444-53349-4.00163-1Functional PEG-based polymers with reactive groups via anionic ROP of tailor-made epoxides (2012)Polymer chemistry, 3(7), 1714-1721. Mangold, C., Wurm, F. & Frey, H.https://doi.org/10.1039/c2py00489eSquaric acid mediated synthesis and biological activity of a library of linear and hyperbranched poly(glycerol)-protein conjugates (2012)Biomacromolecules, 13(4), 1161-1171. Wurm, F., Dingels, C., Frey, H. & Klok, H. A.https://doi.org/10.1021/bm300103uFunctional, hyperbranched polyesters via Baylis-Hillman polymerization (2012)Journal of polymer science. Part A: Polymer chemistry, 50(1), 25-34. Ji, S., Bruchmann, B., Wurm, F. & Klok, H. A.https://doi.org/10.1002/pola.24954Unsaturated polyphosphoesters via acyclic diene metathesis polymerization (2012)Macromolecules, 45(21), 8511–8518. Marsico, F., Wagner, M., Landfester, K. & Wurm, F. R.https://doi.org/10.1021/ma301508s

2011

From an epoxide monomer toolkit to functional PEG copolymers with adjustable LCST behavior (2011)Macromolecular rapid communications, 32(23), 1930-1934. Mangold, C., Obermeier, B., Wurm, F. & Frey, H.https://doi.org/10.1002/marc.201100489Polymers interfacing with biology (2011)Chimia, 65(9), 659-662. Wurm, F. & Klok, H.-A.https://doi.org/10.2533/chimia.2011.659PEG-based multifunctional polyethers with highly reactive vinyl-ether side chains for click-type functionalization (2011)Macromolecules, 44(16), 6326-6334. Mangold, C., Dingels, C., Obermeier, B., Frey, H. & Wurm, F.https://doi.org/10.1021/ma200898nMultifunctional poly(ethylene glycol)s (2011)Angewandte Chemie (international edition), 50(35), 7988-7997. Obermeier, B., Wurm, F., Mangold, C. & Frey, H.https://doi.org/10.1002/anie.201100027Multifunktionelle Poly(ethylenglycole) (2011)Angewandte Chemie, 123(35), 8136-8146. Obermeier, B., Wurm, F., Mangold, C. & Frey, H.https://doi.org/10.1002/ange.201100027Arginine-specific protein modification using α-oxo-aldehyde functional polymers prepared by atom transfer radical polymerization (2011)Polymer chemistry, 2(7), 1490-1498. Gauthier, M. A., Ayer, M., Kowal, J., Wurm, F. R. & Klok, H. A.https://doi.org/10.1039/c0py00422gRapid access to polyfunctional lipids with complex architecture via oxyanionic ring-opening polymerization (2011)Macromolecules, 44(12), 4648-4657. Hofmann, A. M., Wurm, F. & Frey, H.https://doi.org/10.1021/ma200367cAsymmetric micellization of oragnometallic polyether block copolymers (2011)In Non-Conventional Functional Block Copolymers (pp. 103-115) (ACS Symposium Series; Vol. 1066). American Chemical Society. Mangold, C., Wurm, F. & Kilbinger, A. F. M.https://doi.org/10.1021/bk-2011-1066.ch008Linear-dendritic block copolymers: The state of the art and exciting perspectives (2011)Progress in polymer science, 36(1), 1-52. Wurm, F. & Frey, H.https://doi.org/10.1016/j.progpolymsci.2010.07.009

2010

Chiroptical induction and molecular recognition in optically active hyperbranched polyethers with inherently chiral benzophenone core (2010)Macromolecules, 43(23), 9583-9587. Pastor-Pérez, L., Kemmer-Jonas, U., Wurm, F., Stiriba, S. E., Pérez-Prieto, J. & Frey, H.https://doi.org/10.1021/ma101660s"Functional poly(ethylene glycol)": PEG-based random copolymers with 1,2-diol side chains and terminal amino functionality (2010)Macromolecules, 43(20), 8511-8518. Mangold, C., Wurm, F., Obermeier, B. & Frey, H.https://doi.org/10.1021/ma1015352Hyperbranched PEG by random copolymerization of ethylene oxide and glycidol (2010)Macromolecular rapid communications, 31(20), 1811-1815. Wilms, D., Schömer, M., Wurm, F., Hermanns, M. I., Kirkpatrick, C. J. & Frey, H.https://doi.org/10.1002/marc.201000329Multihydroxyl-functional polystyrenes in continuous flow (2010)Macromolecules, 43(13), 5582-5588. Tonhauser, C., Wilms, D., Wurm, F., Berger-Nicoletti, E., Maskos, M., Lowe, H. & Frey, H.https://doi.org/10.1021/ma902849rα, ωn-heterotelechelic hyperbranched polyethers solubilize carbon nanotubes (2010)Macromolecular chemistry and physics, 211(8), 932-939. Wurm, F., Hofmann, A. M., Thomas, A., Dingels, C. & Frey, H.https://doi.org/10.1002/macp.200900652Amino functional poly(ethylene glycol) copolymers via protected amino glycidol (2010)Macromolecules, 43(5), 2244-2251. Obermeier, B., Wurm, F. & Frey, H.https://doi.org/10.1021/ma902245dHyperbranched polyglycerol-based lipids via oxyanionic polymerization: Toward multifunctional stealth liposomes (2010)Biomacromolecules, 11(3), 568-574. Hofmann, A. M., Wurm, F., Huhn, E., Nawroth, T., Langguth, P. & Frey, H.https://doi.org/10.1021/bm901123jHetero-multifunctional poly(ethylene glycol) copolymers with multiple hydroxyl groups and a single terminal functionality (2010)Macromolecular rapid communications, 31(3), 258-264. Mangold, C., Wurm, F., Obermeier, B. & Frey, H.https://doi.org/10.1002/marc.200900472Rapid synthesis and MALDI-ToF characterization of polyethylene oxide multiarm star polymers (2010)Macromolecular chemistry and physics, 211(1), 35-44. Doycheva, M., Berger-Nicoletti, E., Wurm, F. & Frey, H.https://doi.org/10.1002/macp.200900377

2009

Long-chain branched ROMP polymers (2009)Journal of polymer science. Part A: Polymer chemistry, 47(24), 6932-6940. Hilf, S., Wurm, F. & Kilbinger, A. F. M.https://doi.org/10.1002/pola.23733Polymere Janus-Partikel (2009)Angewandte Chemie, 121(45), 8564-8574. Wurm, F. & Kilbinger, A.https://doi.org/10.1002/ange.200901735Polymeric janus particles (2009)Angewandte Chemie (international edition), 48(45), 8412-8421. Wurm, F. & Kilbinger, A. F. M.https://doi.org/10.1002/anie.200901735Hyperbranched-linear-hyperbranched ABA-type block copolymers based on poly(ethylene oxide) and polyglycerol (2009)Polymer international, 58(9), 989-995. Wurm, F., Kemmer-Jonar, U. & Frey, H.https://doi.org/10.1002/pi.2619Electroactive linear-hyperbranched block copolymers based on linear poly(ferrocenylsilane)s and hyperbranched poly (carbosilane)s (2009)Chemistry : a European journal, 15(36), 9068 – 9077. Wurm, F., Hilf, S. & Frey, H.https://doi.org/10.1002/chem.200900666Branched versus linear polyisoprene: Flory-huggins interaction parameters for their solutions in cyclohexane (2009)Macromolecular chemistry and physics, 210(17), 1433-1439. Eckelt, J., Samadi, F., Wurm, F., Frey, H. & Wolf, B. A.https://doi.org/10.1002/macp.200900191Synthesis and noncovalent protein conjugation of linear-hyperbranched PEG-poly(glycerol) α,ωn-telechelics (2009)Journal of the American Chemical Society, 131(23), 7954-7955. Wurm, F., Klos, J., Räder, H. J. & Frey, H.https://doi.org/10.1021/ja9019148Ferrocenyl-functionalized long chain branched polydienes (2009)Journal of polymer science. Part A: Polymer chemistry, 47(10), 2518-2529. Wurm, F., López-Villanueva, F. J. & Frey, H.https://doi.org/10.1002/pola.23334Hyperbranched polyglycerols with elevated molecular weights: A facile two-step synthesis protocol based on polyglycerol Macroinitiators (2009)Macromolecules, 42(9), 3230-3236. Wilms, D., Wurm, F., Nieberle, J., Böhm, P., Kemmer-Jonas, U. & Frey, H.https://doi.org/10.1021/ma802701g

2008

Amphiphilic Linear-Hyperbranched block copolymers with linear poly(ethylene oxide) and hyperbranched poly(carbosilane) block (2008)Macromolecules, 41(24), 9602-9611. Wurm, F., Schüle, H. & Frey, H.https://doi.org/10.1021/ma8018427Carbanions on tap - Living anionic polymerization in a microstructured reactor (2008)Macromolecular chemistry and physics, 209(11), 1106-1114. Wurm, F., Wilms, D., Klos, J., Löwe, H. & Frey, H.https://doi.org/10.1002/macp.200700613Janus micelles induced by olefin metathesis (2008)Journal of the American Chemical Society, 130(18), 5876-5877. Wurm, F., König, H. M., Hilf, S. & Kilbinger, A. F. M.https://doi.org/10.1021/ja801919yBranched and functionalized polybutadienes by a facile two-step synthesis (2008)Macromolecular chemistry and physics, 209(7), 675-684. Wurm, F., López-Villanueva, F. J. & Frey, H.https://doi.org/10.1002/macp.200700574Synthesis and characterization of poly(glyceryl glycerol) block copolymers (2008)Macromolecules, 41(6), 1909-1911. Wurm, F., Nieberle, J. & Frey, H.https://doi.org/10.1021/ma702458gIonic polymerizations in microstructured reactors (2008)Chimica oggi = Chemistry today, 26(2), 32-36. Wilms, D., Wurm, F., Klos, J., Löwe, H. & Frey, H.Double-Hydrophilic Linear-Hyperbranched Block Copolymers Based on Poly(ethylene oxide) and Poly(glycerol) (2008)Macromolecules, 41(4), 1184–1188. Wurm, F., Nieberle, J. & Frey, H.https://doi.org/10.1021/ma702308gWell-defined hyperbranched and linear polymers by anionic polymerization in continuous flow (2008)In 10th International Conference on Microreaction Technology, IMRET 2008 - Topical Conference at the 2008 AIChE Spring National Meeting (pp. 28-35). American Institute of Chemical Engineers. Wilms, D., Wurm, F., Klos, J., Löwe, H. & Frey, H.

2007

Cover Picture Macromol. Rapid Commun. 6/2007 (2007)Macromolecular rapid communications, 28(6), 681-681. López-Villanueva, F.-J., Wurm, F., Kilbinger, A. F. M. & Frey, H.https://doi.org/10.1002/marc.200790011A facile two-step route to branched polyisoprenes via AB n-macromonomers (2007)Macromolecular rapid communications, 28(6), 704-709. López-Villanueva, F.-J., Wurm, F., Kilbinger, A. F. M. & Frey, H.https://doi.org/10.1002/marc.200600782Pencil lead as a matrix for MALDI-ToF mass spectrometry of sensitive functional polymers (2007)Macromolecules, 40(3), 746–751. Berger-Nicoletti, E., Wurm, F., Kilbinger, A. F. M. & Frey, H.https://doi.org/10.1021/ma062458cAutomated large-scale synthesis of supramolecular oligo(p-benzamide) block copolymers (2007)Macromolecules, 40(22), 7827–7833. Klos, J., Wurm, F., König, H. M. & Kilbinger, A. F. M.https://doi.org/10.1021/ma0710378

Research profiles

Frederik teaches Organic and Polymer Chemistry and materials in several study programs displayed below. For further information, please contact the study advisor or Frederik.

Affiliated study programs

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

Get in contact for more projects and descriptions or check out our Twitter account. A research summary is found on the SPC website.

Website research group: https://www.utwente.nl/en/tnw/spc/


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In the press

November 2025 - Opinion piece for One Earth on Sustainable Polymers

November 2025 - Frederik and the LigniLabs team in German TV

November 2023 - salon.com interviewed Frederik about bioplastics 

July 2023 - Frederik talks about the new labs for LigniLabs in the newspaper „Mainzer Allgemeine“

June 2023 - Frederik talks about nanotechnology and prospects of the spin-off company LigniLabs with IHK

March 2023 - Interview about "forever chemicals" for heute journal (ZDF, German TV):

September 2022 - Interview about plastic bags and alternatives in supermarkets:

September 2022 - Interview in "Die Zeit" on recycled plastic toys:

August 2022 - Frederik talks with the newspaper „Mainzer Allgemeine“ about the Spin-Off company LigniLabs and lignin microcarriers

February 2022 -  Interview for "Der Spiegel" - Plastic waste problem:

October 2021 -  Interview for Spektrum on seawater-degradable polymers

October 2020 -  A chance for bioplastics - article in Spektrum.

June 2020 - Youtube video about plastic and sustainable alternatives

November 2019 – Youtube summary of Future award on drug delivery in plants:

July 2019 – TV broadcast (BR Alpha) Campus TV about reducing pesticides in agriculture and the use of biobased and biodegradable polymer carriers.

July 2019 – Interview of “The Guardian” about biodegradable polymers

June 2019 – Interview and TV broadcast for Sat.1 (regional TV news) about biobased and biodegradable nanocarriers in agriculture

May 2019 – Interview for Heise Verlag (Journal “Technology Review”) “Gutes Plastik – schlechtes Plastik“

May 2019 – Interview for Plastisphere Blog about biodegradable polymers

April 2019 – Interview with Dresdner Morgenpost on Sustainable Polymer Packaging

February 2019 TV Interview about polymer packaging and degradable polymers in 3sat

September 2018 Radio Broadcast in “Deutschlandfunk” about Drug Delivery in Agriculture.

September 2018 TV Beitrag in 3sat Nano about Biodegradable Polymer Packaging and composting.

August 2018 Interview in ZEIT online “Was, wenn nicht Plastik?” - about biodegradable polymers and packaging.

July 2018 Radio Broadcast in „SWR Aktuell“ (Frederik explains nanotechnology for treating grapevine plants)

June 2018 Radio Broadcast in „Deutschlandfunk“ (Frederik was interviewed about plastics and recycling).

June 2018 Public panel discussion about plastic packaging (“Leben im Plastikzeitalter: Wie ist ein nachhaltiger Umgang mit Plastik möglich?“, Frankfurt Institute for Social-Ecological Research).

June 2018 Journal Article in profil.at (Frederik was interviewed about degradable polyethylene alternatives)

June 2018 Radio broadcast at „Bayern 2” (Radioshow: IQ, Frederik was interviewed about nanotechnology for agricultural use)

May 2018 Journal Article “Plastik, gut verträglich." The research on biodegradable polymers of the "Functional Polymers" group was highlighted in the Max Planck Forschung Research Journal.

May 2018 Journal Interview for the journal EURO (Frederik interviewed about polymers in daily life)

April 2018 Article for schools: Techmax (Link: https://www.max-wissen.de/ ) about microplastics and degradable polymers. Our research about degradable polymers summarized (in German) for schools in Germany.

April 2018 Journal Article in “Gesunde Pflanzen (2018) 70:109–113“ – about treatment of plant diseases with biodegradable nanocarriers

February 2018 Youtube Video about BioRescue online (“BIOrescue - A novel biorefinery concept for mushroom compost”)

November 2017 Radio Interview; Frederik was interviewed about reusable plastic bags in supermarkets.

August 2017 Journal Article; The research about biodegradable polymers of the group was highlighted in “Chemie Extra” (ChemieXtra 7-8/2017)

April 2017 Public panel discussion at the Max-Planck-Forum (Berlin) – “Plastik – nicht nur Müll“

November 2016 Journal Article in “DocCheck” about our Research on the “Stealth” Effect of Nanocarriers

September 2016 Journal Article in “Krebs Nachrichten” on the “Stealth” Effect of Nanocarriers

News on utwente.nl

December 2023 - NWO Perspektief Proposal SusInkCoat granted - research on biodegradable and recyclable coatings and inks 

February 2023 - Our master students from the AMM Organic Materials and Polymer Science Class publish a review article on accelerated biodegradation in polymer blends and composites

December 2022 - Take-Off and TTT grants on research on biodegradable polyphosphoester - together with Timo Rheinberger and Olga Koshkina

November 2022 - Our master students from the AMM Organic Materials and Polymer Science Class publish a review article on composting of polyesters in the journal Waste Managment

November 2022 - Frederik‘s Inaugural lecture

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