prof.dr. H.E. Vonkeman (Harald)


About Me


My aim is to advance research that facilitates a transition of care, in which healthcare supported by technology is increasingly being delivered at a distance from healthcare institutions, in a way that is both meaningful to patients and has added value to society. To achieve this, I intend to further develop a platform and network that facilitates collaboration between patients, scientists, medical specialists, primary care professionals and tech companies, that stimulates development of innovative health technologies and accelerates access to evidence-based technological innovations in healthcare.

As a physician, my main aim has been to enhance quality of life of patients living with chronic rheumatic diseases. Although this work has significantly improved long term outcomes of patients, I have found that there are often striking discrepancies in perceptions of disease between patients and caregivers. Much of my research has been on measuring and using patients’ perspectives as goals of treatment, i.e., outcomes that are relevant to patients; such as pain, fatigue, physical function and participation. These outcomes are often multidimensional and complex, difficult to measure and even harder to use in treatment strategies. In recent years this work has branched out to the development and implementation of Value Based Health Care. 

The role of Health Technology has become increasingly important in the way professionals diagnose, treat and monitor patients, in healthcare institutions and increasingly also at home, as well as for patients themselves. Projects aimed at using innovative technology to measure and improve outcomes involve telemonitoring of chronic diseases, computer adaptive tests, pain threshold measurement and therapeutic use of virtual reality.

As a board member of the Dutch Society for Rheumatology (NVR), charged with the portfolio Training & Education, and as director of the MST Rheumatology Fellowship, I endeavor to include innovative health technology in future medical intern- and fellowships of physicians and nurses.


Medicine & Life Sciences
Antirheumatic Agents
Drug-Related Side Effects And Adverse Reactions
Patient Reported Outcome Measures
Rheumatoid Arthritis
Tumor Necrosis Factor Inhibitors

Ancillary Activities

  • Medisch Spectrum Twente
    Medical Specialist


ISARIC Clinical Characterisation Group (2023). Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19. International journal of epidemiology, 52(2), 355-376. https://doi.org/10.1093/ije/dyad012
Wainstein, M., Spyrison, N., Dai, D., Ghadimi, M., Chávez-Iñiguez, J. S., Claure-Del Granado, R. , Brusse-Keizer, M. , Haalboom, M. , Nguyen, D. , Silva, C. , van der Palen, J. , Vonkeman, H., & ISARIC Characterization Group (2023). Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19. Kidney International Reports, 8(8), 1514-1530. https://doi.org/10.1016/j.ekir.2023.05.015
Velthuis, K., Poppelaars, F. , ten Klooster, P. M., Jessurun, N. T. , & Vonkeman, H. E. (2023). Medicamenteuze behandelroutes van nieuw-gediagnosticeerde RA-patiënten: verschillen tussen patiënten met en zonder bijwerkingen. Nederlands tijdschrift voor reumatologie, 2023(2), 52-55.
van Lint, J. A., Jessurun, N. T., Tas, S. W. , Vonkeman, H. E., van Doorn, M. B. A., Hoentjen, F., Nurmohamed, M. T., van Puijenbroek, E. P., & van den Bemt, B. J. F. (2023). Recurring Fatigue After Biologic Administration: Patient-Reported Data from the Dutch Biologic Monitor. BioDrugs, 37(4), 541-550. Advance online publication. https://doi.org/10.1007/s40259-023-00592-8
Gosselt, H. R., van Lint, J. A., Kosse, L. J., Spuls, P. I. , Vonkeman, H. E., Tas, S. W., Hoentjen, F., Nurmohamed, M. T., van den Bemt, B. J. F., van Doorn, M. B. A., & Jessurun, N. T. (2023). Sex differences in adverse drug reactions from Adalimumab and etanercept in patients with inflammatory rheumatic diseases. Expert opinion on drug safety, 22(6), 501-507. Advance online publication. https://doi.org/10.1080/14740338.2023.2181340

UT Research Information System

Contact Details

Visiting Address

University of Twente
Faculty of Behavioural, Management and Social Sciences
Cubicus (building no. 41), room B131B
De Zul 10
7522NJ  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Behavioural, Management and Social Sciences
Cubicus  B131B
P.O. Box 217
7500 AE Enschede
The Netherlands