Guest staff

prof.dr. H.E. Vonkeman (Harald)

Honorary Professor
BMS-HIB-PHT
Capitool 15 138
h.e.vonkeman@utwente.nl
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CHAIR PATIENT CENTERED HEALTH TECHNOLOGY

My aim is to advance research that facilitates a transition of care, in which healthcare supported by technology is increasingly being delivered at a distance from healthcare institutions, in a way that is both meaningful to patients and has added value to society. To achieve this, I intend to further develop a platform and network that facilitates collaboration between patients, scientists, medical specialists, primary care professionals and tech companies, that stimulates development of innovative health technologies and accelerates access to evidence-based technological innovations in healthcare.

As a physician, my main aim has been to enhance quality of life of patients living with chronic rheumatic diseases. Although this work has significantly improved long term outcomes of patients, I have found that there are often striking discrepancies in perceptions of disease between patients and caregivers. Much of my research has been on measuring and using patients’ perspectives as goals of treatment, i.e., outcomes that are relevant to patients; such as pain, fatigue, physical function and participation. These outcomes are often multidimensional and complex, difficult to measure and even harder to use in treatment strategies. In recent years this work has branched out to the development and implementation of Value Based Health Care. 

The role of Health Technology has become increasingly important in the way professionals diagnose, treat and monitor patients, in healthcare institutions and increasingly also at home, as well as for patients themselves. Projects aimed at using innovative technology to measure and improve outcomes involve telemonitoring of chronic diseases, computer adaptive tests, pain threshold measurement and therapeutic use of virtual reality.

As a board member of the Dutch Society for Rheumatology (NVR), charged with the portfolio Training & Education, and as director of the MST Rheumatology Fellowship, I endeavor to include innovative health technology in future medical intern- and fellowships of physicians and nurses.

Expertise

  • Medicine and Dentistry

    • Patient
    • Rheumatoid Arthritis
    • Inpatient
    • Spondylarthritis
    • Disease Activity
    • Therapeutic Procedure
    • Pain
    • TNF Inhibitor

Organisations

Ancillary activities

  • Medisch Spectrum TwenteMedical Specialist

Publications

2026

A GPT-reinforced social robot for patient communication: a pilot study (2026)Frontiers in Digital Health, 7. Article 1653168. van 't Klooster, J. W. J. R., Capasso, M., van Gorssel, D., Vrolijk, E., Rettagliata, G., Gerritsen, D., Hegeman, M. C., Tauro , E., Caiani , E. G. & Vonkeman, H. E.https://doi.org/10.3389/fdgth.2025.1653168Preferences regarding technology to unobtrusively monitor symptoms in rheumatoid arthritis: a qualitative study using focus group discussions (2026)Rheumatology international, 46(1). Article 13. Wolkorte, R., Vonkeman, H. E. & Tuijthof, G. J. M.https://doi.org/10.1007/s00296-025-06041-9

2025

Almost half of the patients with axial spondyloarthritis reporting an acceptable symptom state have high disease activity; data from two standard-of-care cohorts (2025)Seminars in arthritis & rheumatism, 77. Article 152903 (E-pub ahead of print/First online). Carbo, M., Kampman, A., Paap, D., Wink, F., Webers, C., Vonkeman, H., van Tubergen, A., Arends, S. & Spoorenberg, A.https://doi.org/10.1016/j.semarthrit.2025.152903PeRsonalIsed MEdicine in Rheumatoid Arthritis (PRIMERA) trial: a multicentre, open-label, randomised controlled trial comparing routine care with a tailor-made approach (2025)BMJ open, 15(12). Article e108887. Dag, H. H., Looijen, A. E. M., Vonkeman, H. E., Willemze, A., Korswagen, L. A., Padmos, R. C., van Gaalen, F. A., Tchetverikov, I., van der Kaap, J. H., Veris-Van Dieren, J. J., Riyazi, N., Spierings, J., van der Helm-Van Mil, A. H. M. & De Jong, P. H. P.https://doi.org/10.1136/bmjopen-2025-108887The development of a clinical prediction model for response to methotrexate, tofacitinib, and etanercept in patients with Psoriatic Arthritis (2025)Arthritis research & therapy, 27(1). Article 197. Perton, F. T., Bentvelzen, M. L. M., Fadaei, S., Pouw, J. N., Spierings, J., Vonkeman, H. E., Mooij, S. C., Schipper, L. G., Herman, A., Wijngaarden, S., Vreugdenhil, S. A., Vonkeman, H. E., van Tubergen, A. M., Schipper, L. G., Mooij, S. C., Leijten, E. F. A., van Kuijk, A. W. R., Kok, M. R., Kloth, J. S. L., … Welsing, P. M. J.https://doi.org/10.1186/s13075-025-03660-2Improving the quality of life in post-COVID-19-patients: A mixed-methods investigation toward self-management support for post-COVID-19 syndrome (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Schaap, G.https://doi.org/10.3990/1.9789036568562Which ASDAS cut-off corresponds best to treatment intensification in patients with axial spondyloarthritis in daily practice? A prospective study from a clinical registry (2025)Rheumatology international, 45(11). Article 256. Nezam El-Din, R., van Tubergen, A., Vonkeman, H. E. & Webers, C.https://doi.org/10.1007/s00296-025-06011-1Evaluation of a web-based self-monitoring application (MyRA) to empower people with rheumatoid arthritis in daily life (2025)Rheumatology (E-pub ahead of print/First online). Hochstenbach, L. M. J., Verbeek, J. G. E., Brokken-Peters, M. B. J., den Dungen, P. v., Knops, A. M., Spreeuwenberg, M. D., Vonkeman, H. E. & van Tubergen, A. M.https://doi.org/10.1093/rheumatology/keaf565Predictive Value of Severe Symptoms for Residual Disease After Transitioning From High to Low Disease Activity in Axial Spondyloarthritis: A Longitudinal Study (2025)Journal of rheumatology, jrheum.2025-0421. Smits, M. L., Renet, E., Vonkeman, H. E., Webers, C. & van Tubergen, A.https://doi.org/10.3899/jrheum.2025-0421The burden of adverse drug reactions reported by patients in the Dutch ADR monitor:: A proof of concept (2025)Expert opinion on drug safety, 24(9), 1023-1033. Quik, J. M., Gosselt, H. R., van Lint, J. A., Kosse, L. J., ten Klooster, P. M., Vonkeman, H. E., van den Bemt, B. J. F. & Jessurun, N. T.https://doi.org/10.1080/14740338.2024.2383707

Research profiles

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

Address

University of Twente

Capitool 15 (building no. 78), room 138
Capitool 15
7521 PL Enschede
Netherlands

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