Zilverling

dr. H.G.E. Meijer (Hil)

Programme Director Applied Mathematics & Associate Professor
EEMCS-AM-MIA
EEMCS-SERVICES-OLD
Zilverling 2096
h.g.e.meijer@utwente.nl
+31534893416
Business card

Hil Meijer is Programme Director of Applied Mathematics at the University of Twente. He is also an associate professor (UHD) in the MIA group at the Department of Applied Mathematics. He started at the University of Twente in 2007 after finishing his PhD in Mathematics at the University of Utrecht (2006).

Mathematics is a fascinating subject. It isĀ great to share that joy through teaching.

Mathematics is the language of graphs, geometry and other objects, and finds its way in physics, engineering, and data science. Students need aĀ solid training in depth within Mathematics or more goal-oriented for service teaching. As programme director, I shape the setting for my colleagues to provide inspiring maths education.

I use analysis, geometry, numericsĀ and data to characterise dynamical transitions in models.Ā 

My research interests are in applied dynamical systems theory and neuroscience. Model simulations are helpful in understanding a model's behaviour, but we need clever approaches to determine linearised stability. I am a co-developer ofĀ MatCont, a leading numerical bifurcation analysis toolbox, for which I contribute new numerical algorithms and give courses and tutorials on its use.

How can we use neuromodulation to improve neuronal function?

Combining mathematical modelling with numerical analysis, I collaborate with several (clinical) groups to analyse clinical data to improve understanding, diagnostics and protocols. Current projects focus on ion dynamics during energy deprivation (ischemia) and neurostimulation for improved stimulation protocols in epilepsy surgery. Other and previous projects considered sensory processes, such as pain-related somatosensation and neuromodulation with deep brain stimulation for Parkinson's disease, combining models and experiments. I am open to new collaborations.


Teaching includes Mathematical Modelling, Calculus, Linear Algebra, Nonlinear Dynamics, Programming, and Numerical Methods for Biomedical Engineering and Applied Mathematics, Mathematical Neuroscience.

Expertise

  • Neuroscience

    • Neuron
    • Epilepsy
    • Seizure
    • Excitability

  • Medicine and Dentistry

    • Stimulus
    • Stimulation
    • Patient
    • Electro Stimulation

Organisations

Publications

2025

Identification of models describing gene expression data leveraging machine learning methods (2025)Interface focus, 15(3). Article 20250014. Jansen Klomp, L. F., Queirolo, E., Post, J. N., Meijer, H. G. E. & Brune, C.https://doi.org/10.1098/rsfs.2025.0014DANSE: a pipeline for dynamic modelling of time-series multi-omics data (2025)[Working paper › Preprint]. bioRxiv. Klomp, L. F. J., Yan, X., Snabel, R. R., Veenstra, G. J. C., Meijer, H. G. E. & Post, J. N.https://doi.org/10.1101/2025.07.04.663170Atypical plume-like events contribute to glutamate accumulation in metabolic stress conditions (2025)iScience, 28(4). Article 112256. Ziebarth, T., Pape, N., Nelson, J. S. E., van Alphen, F. I. M., Kalia, M., Meijer, H. G. E., Rose, C. R. & Reiner, A.https://doi.org/10.1016/j.isci.2025.112256Widespread neuronal chaos induced by slow oscillating currents (2025)Chaos, 35(3). Article 033120. Scully, J., Hinsley, C., Bloom, D., Meijer, H. G. E. & Shilnikov, A. L.https://doi.org/10.1063/5.0248001

2024

Widespread neuronal chaos induced by slow oscillating currents (2024)[Working paper › Preprint]. ArXiv.org. Scully, J., Hinsley, C., Bloom, D., Meijer, H. G. E. & Shilnikov, A. L.https://doi.org/10.48550/arXiv.2411.06304On choosing activation functions for neural fields (2024)[Contribution to conference › Poster] 9th International Conference on Mathematical Neuroscience, ICMNS 2024. Meijer, H. G. E. & van Harten, W.The effect of propofol on effective brain networks (2024)Clinical neurophysiology, 161(5), 222-230. van Blooijs, D., Blok, S., Huiskamp, G. J. M., Van Eijsden, P., Meijer, H. G. E. & Leijten, F. S. S.https://doi.org/10.1016/j.clinph.2024.01.012Weak coupling of neurons enables very high-frequency and ultra-fast oscillations through the interplay of synchronized phase-shifts (2024)Network Neuroscience, 8(1), 293-318. Přibylová, L., Sevcik, J., Eclerova, V., Klimes, P., Brazdil, M. & Meijer, H. G. E.https://doi.org/10.1162/netn_a_00351

2023

An in silico and inĀ vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome (2023)Stem cell reports, 18(8), 1686-1700. Doorn, N., Hugte, E. J. H. v., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Nadif Kasri, N. & Putten, M. J. A. M. v.https://doi.org/10.1016/j.stemcr.2023.06.003A neural mass model for the EEG in ischemia (2023)[Working paper › Preprint]. bioRxiv. Kalia, M., Ligtenstein, S. L. B., Meijer, H. G. E. & van Putten, M. J. A. M.https://doi.org/10.1101/2023.04.07.535995

Research profiles

Address

University of Twente

Zilverling (building no. 11), room 2096
Hallenweg 19
7522 NH Enschede
Netherlands

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