Zilverling

dr. H.G.E. Meijer (Hil)

Associate Professor
EEMCS-AM-MIA
Zilverling 2096
h.g.e.meijer@utwente.nl
+31534893416
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Hil Meijer is an associate professor (UHD) in the MIA group at the Department of Applied Mathematics. I started at the University of Twente in 2007 after finishing a PhD in Mathematics at the University of Utrecht (2006).

Can we characterise dynamical transitions in models using knowledge from geometry and structure? 

My research interests are in applied dynamical systems theory and neuroscience. Model simulations are helpful in understanding a model's behaviour, but we need clever approaches to determine linearised stability. I am a co-developer of MatCont, a leading numerical bifurcation analysis toolbox, for which I contribute new numerical algorithms and give courses and tutorials on its use.

How can we use neuromodulation to improve neuronal function?

Combining mathematical modelling with numerical analysis, I collaborate with several (clinical) groups to analyse clinical data to improve understanding, diagnostics and protocols. Current projects focus on ion dynamics during energy deprivation (ischemia) and neurostimulation for improved stimulation protocols in epilepsy surgery. Other and previous projects considered sensory processes, such as pain-related somatosensation and neuromodulation with deep brain stimulation for Parkinson's disease, combining models and experiments. I am open to new collaborations.


Teaching includes Mathematical Modelling, Calculus, Linear Algebra, Nonlinear Dynamics, Programming, and Numerical Methods for Biomedical Engineering and Applied Mathematics, Mathematical Neuroscience.

Expertise

  • Neuroscience

    • Neuron
    • Epilepsy
    • Seizure
    • Excitability

  • Medicine and Dentistry

    • Stimulus
    • Stimulation
    • Patient
    • Electro Stimulation

Organisations

Publications

2024

On choosing activation functions for neural fields (2024)[Contribution to conference › Poster] 9th International Conference on Mathematical Neuroscience, ICMNS 2024. Meijer, H. G. E. & van Harten, W.The effect of propofol on effective brain networks (2024)Clinical neurophysiology, 161(5), 222-230. van Blooijs, D., Blok, S., Huiskamp, G. J. M., Van Eijsden, P., Meijer, H. G. E. & Leijten, F. S. S.https://doi.org/10.1016/j.clinph.2024.01.012Weak coupling of neurons enables very high-frequency and ultra-fast oscillations through the interplay of synchronized phase-shifts (2024)Network Neuroscience, 8(1), 293-318. Přibylová, L., Sevcik, J., Eclerova, V., Klimes, P., Brazdil, M. & Meijer, H. G. E.https://doi.org/10.1162/netn_a_00351

2023

An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome (2023)Stem cell reports, 18(8), 1686-1700. Doorn, N., Hugte, E. J. H. v., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Nadif Kasri, N. & Putten, M. J. A. M. v.https://doi.org/10.1016/j.stemcr.2023.06.003

2022

Internal resonance in a MEMS levitation force resonator (2022)Nonlinear Dynamics, 110(2), 1151–1174. Zamanzadeh, M., Meijer, H. G. E. & Ouakad, H. M.https://doi.org/10.1007/s11071-022-07721-yA neural mass model for the EEG in ischemia (2022)[Contribution to conference › Poster] Bridging the Gap: from Brain Mechanics to Brain Dynamics 2022. Kalia, M., Meijer, H. G. E., Ligtenstein, S. L. B. & van Putten, M. J. A. M.Data, models and transitions in computational neuroscience: Bottom-up and top-down approaches (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Kalia, M.https://doi.org/10.3990/1.9789036554091Simulating differentiation from iPS cells to chondrocytes (2022)[Contribution to conference › Poster] Bioinformatics & Systems Biology Conference, BioSB 2022. Jansen Klomp, L., Coutinho de Almeida, R., Meulenbelt, I., Post, J. N. & Meijer, H. G. E.Dynamical neural network reconstruction based on stimulation data (2022)[Contribution to conference › Poster] Perturbations In Epilepsy 2022. Meijer, H. G. E., Jansen Klomp, L. F., Hebbink, G. J., van Blooijs, D., Zijlmans, M. & Huiskamp, G. J. M.Modal interaction in a levitation force MEMS based resonator (2022)In Proceedings of ASME 2021 International Mechanical Engineering Congress and Exposition (IMECE2021). Article V07BT07A064 (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 7B-2021). American Society of Mechanical Engineers. Zamanzadeh, M., Meijer, H. G. E., Jafarsadeghi-Pournaki, I. & Ouakad, H. M.https://doi.org/10.1115/IMECE2021-72755

Research profiles

Address

University of Twente

Zilverling (building no. 11), room 2096
Hallenweg 19
7522 NH Enschede
Netherlands

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