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Hil Meijer is Programme Director of Applied Mathematics at the University of Twente. He is also an associate professor (UHD) in the MIA group at the Department of Applied Mathematics. He started at the University of Twente in 2007 after finishing his PhD in Mathematics at the University of Utrecht (2006).

Mathematics is a fascinating subject. It isĀ great to share that joy through teaching.

Mathematics is the language of graphs, geometry and other objects, and finds its way in physics, engineering, and data science. Students need aĀ solid training in depth within Mathematics or more goal-oriented for service teaching. As programme director, I shape the setting for my colleagues to provide inspiring maths education.

I use analysis, geometry, numericsĀ and data to characterise dynamical transitions in models.Ā 

My research interests are in applied dynamical systems theory and neuroscience. Model simulations are helpful in understanding a model's behaviour, but we need clever approaches to determine linearised stability. I am a co-developer ofĀ MatCont, a leading numerical bifurcation analysis toolbox, for which I contribute new numerical algorithms and give courses and tutorials on its use.

How can we use neuromodulation to improve neuronal function?

Combining mathematical modelling with numerical analysis, I collaborate with several (clinical) groups to analyse clinical data to improve understanding, diagnostics and protocols. Current projects focus on ion dynamics during energy deprivation (ischemia) and neurostimulation for improved stimulation protocols in epilepsy surgery. Other and previous projects considered sensory processes, such as pain-related somatosensation and neuromodulation with deep brain stimulation for Parkinson's disease, combining models and experiments. I am open to new collaborations.


Teaching includes Mathematical Modelling, Calculus, Linear Algebra, Nonlinear Dynamics, Programming, and Numerical Methods for Biomedical Engineering and Applied Mathematics, Mathematical Neuroscience.

Expertise

  • Neuroscience

    • Neuron
    • Epilepsy
    • Seizure
    • Excitability
  • Medicine and Dentistry

    • Stimulus
    • Stimulation
    • Patient
    • Electro Stimulation

Organisations

Publications

2025

DANSE: A pipeline for dynamic modelling of time-series multi-omics data (2025)BMC bioinformatics, 27(1). Article 28 (E-pub ahead of print/First online). Jansen Klomp, L. F., Yan, X., Snabel, R. R., Veenstra, G. J. C., Meijer, H. G. E. & Post, J. N.https://doi.org/10.1186/s12859-025-06354-3New functionalities in MatCont: delay equations and Lyapunov exponents (2025)[Working paper › Preprint]. ArXiv.org. Liessi, D., Santi, E., Vermiglio, R., Thakur, M., Meijer, H. G. E. & Scarabel, F.https://doi.org/10.48550/arXiv.2504.12785Identification of models describing gene expression data leveraging machine learning methods (2025)Interface focus, 15(3). Article 20250014. Jansen Klomp, L. F., Queirolo, E., Post, J. N., Meijer, H. G. E. & Brune, C.https://doi.org/10.1098/rsfs.2025.0014DANSE: a pipeline for dynamic modelling of time-series multi-omics data (2025)[Working paper › Preprint]. bioRxiv. Klomp, L. F. J., Yan, X., Snabel, R. R., Veenstra, G. J. C., Meijer, H. G. E. & Post, J. N.https://doi.org/10.1101/2025.07.04.663170MODELING CARTILAGE FATE: ADVANCING OA TREATMENTS AND CHONDROCYTE DIFFERENTIATION (2025)Osteoarthritis and cartilage, 33(Supplement), S108. Klomp, L. J., Schivo, S., Kannan, S., Meijer, H. & Post, J.https://doi.org/10.1016/j.joca.2025.02.146Atypical plume-like events contribute to glutamate accumulation in metabolic stress conditions (2025)iScience, 28(4). Article 112256. Ziebarth, T., Pape, N., Nelson, J. S. E., van Alphen, F. I. M., Kalia, M., Meijer, H. G. E., Rose, C. R. & Reiner, A.https://doi.org/10.1016/j.isci.2025.112256Widespread neuronal chaos induced by slow oscillating currents (2025)Chaos, 35(3). Article 033120. Scully, J., Hinsley, C., Bloom, D., Meijer, H. G. E. & Shilnikov, A. L.https://doi.org/10.1063/5.0248001

2024

Widespread neuronal chaos induced by slow oscillating currents (2024)[Working paper › Preprint]. ArXiv.org. Scully, J., Hinsley, C., Bloom, D., Meijer, H. G. E. & Shilnikov, A. L.https://doi.org/10.48550/arXiv.2411.06304On choosing activation functions for neural fields (2024)[Contribution to conference › Poster] 9th International Conference on Mathematical Neuroscience, ICMNS 2024. Meijer, H. G. E. & van Harten, W.The effect of propofol on effective brain networks (2024)Clinical neurophysiology, 161(5), 222-230. van Blooijs, D., Blok, S., Huiskamp, G. J. M., Van Eijsden, P., Meijer, H. G. E. & Leijten, F. S. S.https://doi.org/10.1016/j.clinph.2024.01.012

Research profiles

Courses academic year 2026/2027

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2025/2026

Courses academic year 2024/2025

Address

University of Twente

Zilverling (building no. 11), room 2096
Hallenweg 19
7522 NH Enschede
Netherlands

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