dr. H.G.E. Meijer (Hil)

Associate Professor
EEMCS-AM-MIA
Zilverling 2096
h.g.e.meijer@utwente.nl
+31534893416
Business card

Hil Meijer is an associate professor (UHD) in the MIA group at the Department of Applied Mathematics. I started at the University of Twente in 2007 after finishing a PhD in Mathematics at the University of Utrecht (2006).

Can we characterise dynamical transitions in models using knowledge from geometry and structure? 

My research interests are in applied dynamical systems theory and neuroscience. Model simulations are helpful in understanding a model's behaviour, but we need clever approaches to determine linearised stability. I am a co-developer of MatCont, a leading numerical bifurcation analysis toolbox, for which I contribute new numerical algorithms and give courses and tutorials on its use.

How can we use neuromodulation to improve neuronal function?

Combining mathematical modelling with numerical analysis, I collaborate with several (clinical) groups to analyse clinical data to improve understanding, diagnostics and protocols. Current projects focus on ion dynamics during energy deprivation (ischemia) and neurostimulation for improved stimulation protocols in epilepsy surgery. Other and previous projects considered sensory processes, such as pain-related somatosensation and neuromodulation with deep brain stimulation for Parkinson's disease, combining models and experiments. I am open to new collaborations.


Teaching includes Mathematical Modelling, Calculus, Linear Algebra, Nonlinear Dynamics, Programming, and Numerical Methods for Biomedical Engineering and Applied Mathematics, Mathematical Neuroscience.

Expertise

  • Neuroscience

    • Neuron
    • Epilepsy
    • Seizure
    • Excitability

  • Medicine and Dentistry

    • Stimulus
    • Stimulation
    • Patient
    • Electro Stimulation

Organisations

Publications

2024
The effect of propofol on effective brain networksClinical neurophysiology, 161(5), 222-230. van Blooijs, D., Blok, S., Huiskamp, G. J. M., Van Eijsden, P., Meijer, H. G. E. & Leijten, F. S. S.https://doi.org/10.1016/j.clinph.2024.01.012
2023
Weak coupling of neurons enables very high-frequency and ultra-fast oscillations through the interplay of synchronized phase-shiftsNetwork Neuroscience, 8(1), 293-318 (E-pub ahead of print/First online). Přibylová, L., Sevcik, J., Eclerova, V., Klimes, P., Brazdil, M. & Meijer, H. G. E.https://doi.org/10.1162/netn_a_00351An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndromeStem cell reports, 18(8), 1686-1700. Doorn, N., Hugte, E. J. H. v., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Nadif Kasri, N. & Putten, M. J. A. M. v.https://doi.org/10.1016/j.stemcr.2023.06.003
2022
Internal resonance in a MEMS levitation force resonatorNonlinear Dynamics, 110(2), 1151–1174. Zamanzadeh, M., Meijer, H. G. E. & Ouakad, H. M.https://doi.org/10.1007/s11071-022-07721-yA neural mass model for the EEG in ischemia. Kalia, M., Meijer, H. G. E., Ligtenstein, S. L. B. & van Putten, M. J. A. M.Data, models and transitions in computational neuroscience: Bottom-up and top-down approaches. University of Twente. Kalia, M.https://doi.org/10.3990/1.9789036554091Simulating differentiation from iPS cells to chondrocytes. Jansen Klomp, L., Coutinho de Almeida, R., Meulenbelt, I., Post, J. N. & Meijer, H. G. E.Dynamical neural network reconstruction based on stimulation data. Meijer, H. G. E., Jansen Klomp, L. F., Hebbink, G. J., van Blooijs, D., Zijlmans, M. & Huiskamp, G. J. M.Modal interaction in a levitation force MEMS based resonatorIn Proceedings of ASME 2021 International Mechanical Engineering Congress and Exposition (IMECE2021), Article V07BT07A064. American Society of Mechanical Engineers. Zamanzadeh, M., Meijer, H. G. E., Jafarsadeghi-Pournaki, I. & Ouakad, H. M.https://doi.org/10.1115/IMECE2021-72755
2021
Glial chloride homeostasis under transient ischemic stressFrontiers in cellular neuroscience, 15, Article 735300. Engels, M., Kalia, M., Rahmati, S., Petersilie, L., Kovermann, P., van Putten, M. J. A. M., Rose, C. R., Meijer, H. G. E., Gensch, T. & Fahlke, C.https://doi.org/10.3389/fncel.2021.735300

Research profiles

Address

Visiting address

University of Twente

Zilverling (building no. 11), room 2096
Hallenweg 19
7522 NH Enschede
Netherlands

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