University of Twente
People

Welcome...

H.H.T. Goosen - Middelkamp MSc (Heleen)

PhD Candidate

About Me

Heleen obtained her BSc. Biomedical laboratory research at Saxion University of Applied Sciences in Enschede. Her BSc. thesis was performed at the University of Iowa (US) and was focussed on measuring the in vivo effects of a new anti-cancer compound. Her MSc. in Health Sciences was obtained at the University of Twente, where her Master thesis was focussed on the possibility of improving the drug development process using Organs-on-Chips. After graduating, she started at AST as a researcher where she combined both her research programmes and incorporated MCDA models in the development of a thrombosis-on-a-chip model. She then proceeded in the collaborative TURBO project together with the Radboud University Medical Center and which involved differentiating cells in a microfluidic platform with the intention to develop a blood-brain-barrier-on-a-chip model.

Her current project is focused on Parallelized 3D Blood Vessels-on-a-Chip for Vascular Disease Modelling.

Expertise

Medicine & Life Sciences
# Endothelial Cells
# Induced Pluripotent Stem Cells
# Microfluidics
# Technology
# Thrombosis
Engineering & Materials Science
# Angiography
# Blood Vessels
# Microfluidics

Organisations

Publications

Recent
Le, K. , Goosen - Middelkamp, H. H. T., Do, L., Netea, M., Jonkers, I., Orlova, V., Withoff, S. , van der Meer, A., & Kumar, V. (2022). A Blood-vessel-on-chip to characterize trained immunity in endothelial cells. Poster session presented at EUROoCS Annual Meeting 2022, Grenoble, France.
Middelkamp, H. H. T. , van den Berg, A. , & van der Meer, A. D. (2021). 3D Blood Vessels-on-Chip for atherosclerosis modelling. In 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences: 10-14 October 2021, Palm Springs, CA, USA (pp. 16931694). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).
Paloschi, V., Sabater-Lleal, M. , Middelkamp, H. , Vivas, A., Johansson, S. , van der Meer, A., Tenje, M., & Maegdefessel, L. (2021). Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases. Cardiovascular Research, 117(14), 2742-2754. https://doi.org/10.1093/cvr/cvab088
Albers, H. J., Linssen, J. E. A., Costa, P. F. , Middelkamp, H. H. T., van der Hout, L., Malda, J. , Passier, R. , van den Berg, A. , & van der Meer, A. D. (2020). Using 3D-printing to fabricate a microfluidic vascular model to mimic arterial thrombosis. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 1070-1071). The Chemical and Biological Microsystems Society.
Albers, H. J., da Silva Simão, J. P. , Middelkamp, H. H. T. , Mummery, C. L. , Passier, R. , van den Berg, A., Orlova, V. V. , & van der Meer, A. D. (2018). Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices. In F-G. Tseng, & G-B. Lee (Eds.), MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 2392-2393). The Chemical and Biological Microsystems Society.

UT Research Information System

See all research output of this employee

Google Scholar Link

View my profile

Contact Details

 
 

Visiting Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Carré (building no. 15), room C2243
Hallenweg 23
7522NH  Enschede
The Netherlands

Navigate to location

Mailing Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Carré  C2243
P.O. Box 217
7500 AE Enschede
The Netherlands

Organisations

Social Media

University of Twente Drienerlolaan 5
7522 NB Enschede
+31 (0)53 489 9111
info@utwente.nl
Route