Prof.Dr. H. (Erik) Koffijberg has an MSc in Technical Computer Science from Delft University and a PhD in Decision-Analytic Modelling from Utrecht University in the Netherlands. He is full professor Technology Assessment of Digital Health Innovations and chair of the section Health Technology & Services Research of the faculty Behavioural, Management and Social Sciences at the University of Twente in the Netherlands.

Erik has over 18 years of experience in (early) health technology assessment (HTA) applied to the evaluation of new diagnostic tests, imaging techniques, prediction models, artificial intelligence and medical devices. He has published on, among others, applied analyses focused on cost-effectiveness and budget impact of innovations in cardiology, oncology and neurology. He also developed new simulation techniques to estimate the long-term effects of (preventive) innovations and new selection approaches to improve efficiency of preventive strategies.

Erik teaches MSc and postgraduate external courses on HTA, Health Economic Modeling, Discrete Event Simulation in Healthcare, and Metamodeling. He also coordinates the Healthcare Technology & Management (HCTM) track of the master program Industrial Engineering & Management. He is PI in multiple large (international) research consortia focusing on the optimal use biomarkers, imaging technologies, and AI, for screening or early disease detection. With his research Erik supports the optimal use and implementation of diagnostic innovations in healthcare.

Erik has been a member of several ZonMw committees and of the board of the Dutch Health Economics Association. Currently he is member of the scientific advisory board of the National Healthcare Institute (ZIN).

You can follow Erik on LinkedIn and Twitter

Expertise

  • Medicine and Dentistry

    • Patient
    • Health Care Cost
    • Cost-Effectiveness Analysis
    • Health
    • Therapeutic Procedure
    • Diagnosis
    • Cardiovascular Disease
    • Systematic Review

Organisations

Ancillary activities

  • Zorginstituut NederlandLid wetenschappelijke adviesraad
  • Stichting Health Impact AssessmentBoard member of the “Stichting Health Impact Assessment”.

Publications

2025

Model-based cost-effectiveness studies in nuclear medicine: an unavoidable fact of life (2025)European journal of nuclear medicine and molecular imaging, 53, 24-29. van Mossel, S., Vriens, D., Barnes, A., Muylle, K., Saing, S., Treglia, G., Koffijberg, H. & de Geus-Oei, L. F.https://doi.org/10.1007/s00259-025-07473-yModelling alcohol consumption patterns to enable policy impact assessment (2025)PLoS ONE, 20(12). Article e0327264. ten Dam, J., Rodenburg, A. J., Koffijberg, H., Feenstra, T. L. & van Giessen, A.https://doi.org/10.1371/journal.pone.0327264From Promise to Practice: Evaluating the Health and Economic Impact of AI in Breast Cancer Imaging Surveillance (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Voets, M.https://doi.org/10.3990/1.9789036568982Discrete Event Simulation in R using the ‘Simmer’ Package for Health Economic Modelling: A Tutorial and Illustration in Colon Cancer (2025)Applied health economics and health policy, 23(6), 961-975. Degeling, K., Karnon, J., van de Ven, M., Brennan, A. & Koffijberg, H.https://doi.org/10.1007/s40258-025-00983-8Who Needs Real Data Anyway? Exploring the Use of Synthetic Data in Economic Evaluations of Health Interventions (2025)Value in health, 28(11), 1722-1731. van der Linden, N., Pouwels, X. G. L. V., Jahn, B., Siebert, U. & Koffijberg, H.https://doi.org/10.1016/j.jval.2025.06.007Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study (2025)PharmacoEconomics (E-pub ahead of print/First online). van Well, E. B., Govers, T. M. & Koffijberg, H.https://doi.org/10.1007/s40273-025-01547-3Cost-effectiveness of [18F]FDG PET/CT in follow-up after thermal ablation in patients with colorectal liver metastases in the Dutch healthcare setting (2025)European journal of radiology, 191. Article 112277. van Mossel, S., Bijlstra, O. D., van Delft, F. A., Boekestijn, B., Burgmans, M. C., Hendriks, P., Kapiteijn, E., Mieog, J. S. D., van Persijn van Meerten, E. L., Rietbergen, D. D. D., Feshtali, S. S., Swijnenburg, R. J., de Geus-Oei, L. F. & Koffijberg, H.https://doi.org/10.1016/j.ejrad.2025.112277Making a difference: describing and evaluating the impact of the Dutch CardioVascular Alliance (2025)Netherlands heart journal, 33(10), 307-312. Saing, S., Roos-Hesselink, J. W., Schut, A., van Asselt, T., Abma-Schouten, R., Boels, M. G. S., Tramper, N., van Ofwegen-Hanekamp, C., Willemsen, R., Kip, M. M. A. & Koffijberg, H.https://doi.org/10.1007/s12471-025-01975-yAddressing Subgroup-Specific Treatment Effects to Avoid Inefficient Care: The Conflict Between Statistical and Health Economic Analyses (2025)Value in health, 28(8), 1145-1152. Saing, S., Hannink, G., Geuzinge, H. A. & Koffijberg, H.https://doi.org/10.1016/j.jval.2025.05.004External validation of prediction models for early relapse in advanced epithelial ovarian cancer using Australian and Dutch population-based data (2025)Cancer epidemiology, 97. Article 102824. Said, S. A., IntHout, J., Koffijberg, H., de Hullu, J. A., Hyde, S. E., van der Aa, M. A. & van Altena, A. M.https://doi.org/10.1016/j.canep.2025.102824

Research profiles

Address

University of Twente

Technohal (building no. 18), room 3100
Hallenweg 5
7522 NH Enschede
Netherlands

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Organisations

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