Technohal

prof.dr.ir. H. Koffijberg (Erik)

Full Professor
BMS-TPS-HTSR
Technohal 3100
h.koffijberg@utwente.nl
+31534895384
Business card

Prof.Dr. H. (Erik) Koffijberg has an MSc in Technical Computer Science from Delft University and a PhD in Decision-Analytic Modelling from Utrecht University in the Netherlands. He is full professor Technology Assessment of Digital Health Innovations and chair of the section Health Technology & Services Research of the faculty Behavioural, Management and Social Sciences at the University of Twente in the Netherlands.

Erik has over 18 years of experience in (early) health technology assessment (HTA) applied to the evaluation of new diagnostic tests, imaging techniques, prediction models, artificial intelligence and medical devices. He has published on, among others, applied analyses focused on cost-effectiveness and budget impact of innovations in cardiology, oncology and neurology. He also developed new simulation techniques to estimate the long-term effects of (preventive) innovations and new selection approaches to improve efficiency of preventive strategies.

Erik teaches MSc and postgraduate external courses on HTA, Health Economic Modeling, Discrete Event Simulation in Healthcare, and Metamodeling. He also coordinates the Healthcare Technology & Management (HCTM) track of the master program Industrial Engineering & Management. He is PI in multiple large (international) research consortia focusing on the optimal use biomarkers, imaging technologies, and AI, for screening or early disease detection. With his research Erik supports the optimal use and implementation of diagnostic innovations in healthcare.

Erik has been a member of several ZonMw committees and of the board of the Dutch Health Economics Association. Currently he is member of the scientific advisory board of the National Healthcare Institute (ZIN).

You can follow Erik on LinkedIn and Twitter. 

Expertise

  • Medicine and Dentistry

    • Patient
    • Health Care Cost
    • Cost-Effectiveness Analysis
    • Health
    • Therapeutic Procedure
    • Diagnosis
    • Systematic Review
    • Cardiovascular Disease

Organisations

Ancillary activities

  • Zorginstituut NederlandLid wetenschappelijke adviesraad
  • Stichting Health Impact AssessmentBoard member of the “Stichting Health Impact Assessment”.

Publications

2025

Artificial Intelligence as a New Research Ally? Performing AI-Assisted Systematic Literature Reviews in Health Economics (2025)PharmacoEconomics. Article e072254 (E-pub ahead of print/First online). van Mossel, S., Oude-Wolcherink, M. J., de Feria Cardet, R. E., de Geus-Oei, L. F., Vriens, D., Koffijberg, H. & Saing, S.https://doi.org/10.1007/s40273-025-01481-4External validation of a serum tumor marker algorithm for early prediction of no durable benefit to immunotherapy in metastastic non-small cell lung carcinoma: Tumor Biology (2025)Tumor Biology, 47. Article 14230380251316788 (E-pub ahead of print/First online). Schuurbiers,  . M. F., van Delft,  . A., Koffijberg,  ., IJzerman,  . J., Monkhorst,  ., Ligtenberg,  . J. L., van den Broek,  ., van Rossum,  . H. & van den Heuvel,  . M.https://doi.org/10.1177/14230380251316788A direct comparison in diagnostic performance of CDUS, FDG-PET/CT and MRI in patients suspected of giant cell arteritis (2025)Rheumatology, 64(3), 1392-1399. van Nieuwland, M., Colin, E. M., Vermeer, M., Wagenaar, N. R. L., Vijlbrief, O. D., van Zandwijk, J. K., Slart, R. H. J. A., Koffijberg, H., Jebbink, E. G., van der Geest, K. S. M., Brouwer, E., Boumans, D. & Alves, C.https://doi.org/10.1093/rheumatology/keae171A Systematic Literature Review of Modelling Approaches to Evaluate the Cost Effectiveness of PET/CT for Therapy Response Monitoring in Oncology (2025)PharmacoEconomics, 43(2), 133-151. Article n71. van Mossel, S., de Feria Cardet, R. E., de Geus-Oei, L. F., Vriens, D., Koffijberg, H. & Saing, S.https://doi.org/10.1007/s40273-024-01447-y

2024

Cost-effectiveness analysis of transthoracic echocardiographic assessment in patients with ischemic stroke or TIA of undetermined cause (2024)Journal of Stroke & Cerebrovascular Diseases, 33(12). Article 108013. van der Maten, G., Pouwels, X. G. L. V., Meijs, M. F. L., von Birgelen, C., den Hertog, H. M. & Koffijberg, H.https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108013Strategic placement of volunteer responder system defibrillators (2024)Health care management science, 27, 503–524. Buter, R., Nazarian, A., Koffijberg, H., Hans, E. W., Stieglis, R., Koster, R. W. & Demirtas, D.https://doi.org/10.1007/s10729-024-09685-4Increasing cost-effectiveness of AEDs using algorithms to optimise location (2024)Resuscitation, 201. Article 110300. Buter, R., van Schuppen, H., Stieglis, R., Koffijberg, H. & Demirtas, D.https://doi.org/10.1016/j.resuscitation.2024.110300Validating Health Economic Models With the Probabilistic Analysis Check dashBOARD (2024)Value in health, 27(8), 1073-1084. Pouwels, X. G. L. V., Kroeze, K., van der Linden, N., Kip, M. M. A. & Koffijberg, H.https://doi.org/10.1016/j.jval.2024.04.008A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations (2024)PharmacoEconomics, 42(7), 797-810. Wang, J., Pouwels, X., Ramaekers, B., Frederix, G., van Lieshout, C., Hoogenveen, R., Li, X., de Wit, G. A., Joore, M., Koffijberg, H., van Giessen, A., Knies, S. & Feenstra, T.https://doi.org/10.1007/s40273-024-01376-wWillingness to participate in combination screening for lung cancer, chronic obstructive pulmonary disease and cardiovascular disease in four European countries (2024)European radiology, 34, 4448–4456. Behr, C., Koffijberg, H., IJzerman, M., Kauczor, H. U., Revel, M. P., Silva, M., von Stackelberg, O., van Til, J. & Vliegenthart, R.https://doi.org/10.1007/s00330-023-10474-w

Research profiles

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