Prof.Dr. H. (Erik) Koffijberg has an MSc in Technical Computer Science from Delft University and a PhD in Decision-Analytic Modelling from Utrecht University in the Netherlands. He is full professor Technology Assessment of Digital Health Innovations and chair of the section Health Technology & Services Research of the faculty Behavioural, Management and Social Sciences at the University of Twente in the Netherlands.

Erik has over 18 years of experience in (early) health technology assessment (HTA) applied to the evaluation of new diagnostic tests, imaging techniques, prediction models, artificial intelligence and medical devices. He has published on, among others, applied analyses focused on cost-effectiveness and budget impact of innovations in cardiology, oncology and neurology. He also developed new simulation techniques to estimate the long-term effects of (preventive) innovations and new selection approaches to improve efficiency of preventive strategies.

Erik teaches MSc and postgraduate external courses on HTA, Health Economic Modeling, Discrete Event Simulation in Healthcare, and Metamodeling. He also coordinates the Healthcare Technology & Management (HCTM) track of the master program Industrial Engineering & Management. He is PI in multiple large (international) research consortia focusing on the optimal use biomarkers, imaging technologies, and AI, for screening or early disease detection. With his research Erik supports the optimal use and implementation of diagnostic innovations in healthcare.

Erik has been a member of several ZonMw committees and of the board of the Dutch Health Economics Association. Currently he is member of the scientific advisory board of the National Healthcare Institute (ZIN).

You can follow Erik on LinkedIn and Twitter


  • Medicine and Dentistry

    • Patient
    • Health Care Cost
    • Health
    • Cost-Effectiveness Analysis
    • Therapeutic Procedure
    • Diagnosis
    • Screening
    • Systematic Review


Ancillary activities

  • Zorginstituut NederlandLid wetenschappelijke adviesraad
  • Stichting Health Impact AssessmentBoard member of the “Stichting Health Impact Assessment”.
  • Zorginstituut NederlandLid van werkgroep ACP/WAR/ZIN - omgaan met onzekerheid in prijsadviezen


Introducing Open Science in Teaching Health Economic ModellingPharmacoEconomics - Open, 8, 347-357 (E-pub ahead of print/First online). Pouwels, X. G. L. V. & Koffijberg, H. VTE exclusion in general practice: Using capillary quantitative point-of-care D-dimer testing across various contexts. University of Twente. Heerink, J. S. Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel ConsultationsPharmacoEconomics (E-pub ahead of print/First online). Wang, J., Pouwels, X., Ramaekers, B., Frederix, G., van Lieshout, C., Hoogenveen, R., Li, X., de Wit, G. A., Joore, M., Koffijberg, H., van Giessen, A., Knies, S. & Feenstra, T. and healing of diabetes-related foot ulcers: Motivational interviewing, objective adherence and offloading. University of Twente. Jongebloed-Westra, M. for personalised follow-up in breast cancer: the gap between daily practice and recurrence riskBreast cancer research and treatment, 205, 313-322 (E-pub ahead of print/First online). Voets, M., Hassink, N., Veltman, J., Slump, C. H., Koffijberg, H. & Siesling, S. Value of Information Using Minimal ModellingIn Value of Information for Healthcare Decision-Making (pp. 220-228). CRC Press (Taylor & Francis) (E-pub ahead of print/First online). Rothery, C., Glynn, D. & Koffijberg, H. of home-based screening of the general population for albuminuria to prevent progression of cardiovascular and kidney diseaseEClinicalMedicine, 68, Article 102414. Pouwels, X. G. L. V., Mil, D. v., Kieneker, L. M., Boersma, C., Etten, R. W. v., Evers-Roeten, B., Heerspink, H. J. L., Hemmelder, M. H., Langelaan, M., Thelen, M., Gansevoort, R. T. & Koffijberg, H.
Comment on: “Adding Value to CHEERS: New Reporting Standards for Value of Information Analyses”Applied health economics and health policy (E-pub ahead of print/First online). Kunst, N., Siu, A., Drummond, M., Grimm, S., Grutters, J., Husereau, D., Koffijberg, H., Rothery, C., Wilson, E. C. F. & Heath, A. yield of a proactive strategy for early detection of cardiovascular disease versus usual care in adults with type 2 diabetes or chronic obstructive pulmonary disease in primary care in the Netherlands (RED-CVD): A multicentre, pragmatic, cluster-randomised, controlled trialThe Lancet Public Health (E-pub ahead of print/First online). Groenewegen, A., Zwartkruis, V. W., Rienstra, M., Zuithoff, N. P. A., Hollander, M., Koffijberg, H., Oude Wolcherink, M., Cramer, M. J., van der Schouw, Y. T., Hoes, A. W., Rutten, F. H. & de Boer, R. A. van digitale zorginnovaties: optimalisatie door simulatie. University of Twente. Koffijberg, H.

Research profiles


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