Islam S. M. Khalil received his master's and doctoral degrees in Mechatronics Engineering. He is currently an Associate Professor in the RAM—Robotics and Mechatronics research group at the University of Twente. For two years, he was a post-doctoral fellow in the Robotics and Mechatronics research group and MIRA–Institute for Biomedical Technology and Technical Medicine, University of Twente. After serving as the Director of the Medical Micro and Nanorobotics Laboratory at the German University in Cairo, Egypt, he held a position as an Assistant Professor in the Department of Biomechanical Engineering. His research interests include the modeling and design of motion control systems for soft microrobots, biologically-inspired microrobots, mechatronic system design, and untethered magnetic micro/nanorobotics with applications in micro/nanomanipulation, microassembly, and targeted drug delivery.
Expertise
Physics
- Propulsion
- Magnetic Fields
- Speed
- Frequencies
- Model
- Rotation
Engineering
- Robot
- Microrobots
Organisations
Publications
2024
X-Ray-Guided Magnetic Fields for Wireless Control of Untethered Magnetic Robots in Cerebral Vascular Phantoms (2024)In 2024 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2024 (pp. 4624-4629) (IEEE International Conference on Intelligent Robots and Systems). IEEE. Ligtenberg, L. J. W., De Boer, M. C. J., Mulder, I., Lomme, R., Wasserberg, D., Klein Rot, E. A. M., Ben Ami, D., Sadeh, U., Liefers, H. R., Shoseyov, O., Jonkheijm, P., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1109/IROS58592.2024.10802534Ex vivo validation of magnetically actuated intravascular untethered robots in a clinical setting (2024)Communications Engineering, 3. Article 68. Ligtenberg, L.-J. W., Rabou, N. C. A., Goulas, C., Duinmeijer, W., Halfwerk, F. R., Arens, J., Lomme, R., Magdanz, V., Klingner, A., Klein Rot, E. A. M., Nijland, C. H. E., Wasserberg, D., Liefers, H. R., Jonkheijm, P., Susarrey-Arce, A., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1038/s44172-024-00215-2Exploring sperm cell motion dynamics: Insights from genetic algorithm-based analysis (2024)Computational and Structural Biotechnology Journal, 23, 2837-2850. Klingner, A., Kovalenko, A., Magdanz, V. & Khalil, I. S. M.https://doi.org/10.1016/j.csbj.2024.06.008Magnetic control of soft microrobots near step-out frequency: Characterization and analysis (2024)Computational and Structural Biotechnology Journal, 25, 165-176. Wang, Z., Li, W., Klingner, A., Pei, Y., Misra, S. & S.M. Khalil, I.https://doi.org/10.1016/j.csbj.2024.08.022Controlled Locomotion of IRONSperm Clusters: Evaluating Maneuverability with X-Ray-Guided Magnetic Fields (2024)In 2024 10th IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob) (pp. 883-888). IEEE. K. van der Mijle Meijer, J., Mulder , I., Ligtenberg, L.-J. W., Liefers, H. R., Magdanz, V. & S.M. Khalil, I.https://doi.org/10.1109/BioRob60516.2024.10719702Exploring PEMFCs for Powering Untethered Small-Scale Robots (2024)In 2024 10th IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob) (pp. 753-760) (Proceedings IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob); Vol. 2024). IEEE. Lakshmi Manikandan, A., Gurboga, B., Münzenrieder, N., Raman, A., Gardeniers, H. J. G. E., Susarrey-Arce, A., Abelmann, L. & S.M. Khalil, I.https://doi.org/10.1109/BioRob60516.2024.10719906X-Ray-Guided Robotic Platform for Remote Control of Untethered Magnetic Robots Targeting Blood Clots in the Iliac Artery (2024)In 2024 10th IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob) (pp. 526-531) (Proceedings IEEE RAS/EMBS International Conference for Biomedical Robotics and Biomechatronics (BioRob); Vol. 2024). IEEE. Ligtenberg, L.-J. W., de Jongh, L., Liefers, H. R., Wasserberg, D., Klein Rot, E. A. M., Ben Ami, D., Sadeh, U., Lomme, R. M., Tuijthof, G. G. M., Shoseyov, O., Jonkheijm, P., Warlé, M. & S.M. Khalil, I.https://doi.org/10.1109/BioRob60516.2024.10719845Magnetic alginate microrobots with dual-motion patterns through centrifugally driven flow control (2024)Materials & Design, 246. Article 113337. Wang, Z., Li, W., Li, C., Klingner, A., Pei, Y., Misra, S. & Khalil, I. S. M.https://doi.org/10.1016/j.matdes.2024.113337Advancements in navigation of untethered small-scale helical devices (2024)[Thesis › PhD Thesis - Research external, graduation external]. University of Groningen. Li, C.https://doi.org/10.33612/diss.918484711Soft Bio-Microrobots: Toward Biomedical Applications (2024)Advanced Intelligent Systems, 6(2). Article 2300093. Wang, Z., Klingner, A., Magdanz, V., Misra, S. & S.M. Khalil, I.https://doi.org/10.1002/aisy.202300093Magnetic polycaprolactone microspheres: drug encapsulation and control (2024)International Journal of Polymeric Materials and Polymeric Biomaterials, 73(2), 143-153. El Gohary, N. A., Mahmoud, A., Ashraf Nazmy, M., Zaabalawi, R., El Zahar, L., Khalil, I. S. M. & Mitwally, M. E.https://doi.org/10.1080/00914037.2022.2132248Control of Tetherless Magnetic Helical Devices Using A Synchronized Rotating Magnetic Actuation System. (2024)[Thesis › PhD Thesis - Research external, graduation external]. University of Groningen. Zhang, Z.https://doi.org/10.33612/diss.1079359598Machine Learning Based Tool for Automated Sperm Cell Tracking and Sperm Bundle Detection (2024)In Machine Learning and Knowledge Discovery in Databases. Applied Data Science Track: European Conference, ECML PKDD 2024, Vilnius, Lithuania, September 9–13, 2024, Proceedings, Part X (pp. 19-32) (Lecture Notes in Computer Science; Vol. 14950). Springer. Horenin, J., Magdanz, V., Khalil, I. S. M., Klingner, A., Kovalenko, A. & Čepek, M.https://doi.org/10.1007/978-3-031-70381-2_2Remote Control of Untethered Magnetic Robots within a Lumen using X-Ray-Guided Robotic Platform (2024)In 2024 IEEE International Conference on Robotics and Automation, ICRA 2024 (pp. 17763-17769) (Proceedings - IEEE International Conference on Robotics and Automation; Vol. 2024). IEEE. Ligtenberg, L. J. W., Rabou, N. C. A., Peters, S., Vengetela, T., Schut, V., Liefers, H. R., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1109/ICRA57147.2024.10611161
2023
Helical Propulsion in Low-Re Numbers with Near-Zero Angle of Attack (2023)In 2023 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (pp. 2647-2652). IEEE. Ligtenberg, L.-J. W., Ekkelkamp, I. A. A., Halfwerk, F. R., Goulas, C., Arens, J., Warlé, M. & Khalil, I. S. M.https://doi.org/10.1109/iros55552.2023.10341627Influence of Nanoparticle Coating on the Differential Magnetometry and Wireless Actuation of Biohybrid Microrobots (2023)In 2023 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (pp. 2653-2658). IEEE. Magdanz, V., Cumming, J. R., Salamzadeh, S., Tesselaar, S., Alic, L., Abelmann, L. & S.M. Khalil, I.https://doi.org/10.1109/IROS55552.2023.10341258Navigation of Untethered Small-Scale Helical Devices Using Magnetic System under Ultrasound Guidance (2023)IEEE Transactions on Medical Robotics and Bionics, 5(4), 1093-1104. Li, C., Misra, S. & Khalil, I. S. M.https://doi.org/10.1109/TMRB.2023.3318642IRONSperm swimming by rigid-body rotation versus transverse bending waves influenced by cell membrane charge (2023)Journal of micro-bio robotics, 18(1-2), 49-60. Magdanz, V., Klingnert, A., Abelmann, L. & S.M. Khalil, I.https://doi.org/10.1007/s12213-023-00158-5Input-Output Boundedness of a Magnetically-Actuated Helical Device (2023)In 2023 IEEE International Conference on Robotics and Automation (ICRA 2023) (pp. 5433-5438). IEEE. Ligtenberg, L.-J. W. & S.M. Khalil, I.https://doi.org/10.1109/ICRA48891.2023.10160556Closed-Loop Control Characterization of Untethered Small-Scale Helical Device in Physiological Fluid with Dynamic Flow Rates (2023)Advanced Intelligent Systems, 5(5). Article 2200322. Li, C., Misra, S. & Khalil, I. S. M.https://doi.org/10.1002/aisy.202200322Locomotion of bovine spermatozoa during the transition from individual cells to bundles (2023)Proceedings of the National Academy of Sciences of the United States of America, 120(3). Article e2211911120. Zhang , K., Klingner, A., Le Gars, Y., Misra, S., Magdanz, V. & S.M. Khalil, I.https://doi.org/10.1073/pnas.2211911120Embedded 3D printing of dilute particle suspensions into dense complex tissue fibers using shear thinning xanthan baths (2023)Biofabrication, 15(1). Article 015014. Trikalitis, V. D., Kroese, N. J. J., Kaya, M., Cofino Fabres, C., ten Den, S. A., S.M. Khalil, I., Misra, S., Koopman, B. F. J. M., Passier, R., Schwach, V. & Rouwkema, J.https://doi.org/10.1088/1758-5090/aca124Flagellar Propulsion of Sperm Cells Against a Time-Periodic Interaction Force (2023)Advanced Biology, 7(1). Article 2200210. Wang, Z., Klingnert, A., Magdanz, V., Hoppenreijs, M., Misra, S. & S.M. Khalil, I.https://doi.org/10.1002/adbi.202200210
2022
Visualization of micro-agents and surroundings by real-time multicolor fluorescence microscopy (2022)Scientific reports, 12(1). Article 13375. Kaya, M., Stein, F., Padmanaban, P., Zhang, Z., Rouwkema, J., Khalil, I. S. M. & Misra, S.https://doi.org/10.1038/s41598-022-17297-7Drug-Loaded IRONSperm clusters: modeling, wireless actuation, and ultrasound imaging (2022)Biomedical materials, 17(6). Article 065001. Middelhoek, K., Magdanz, V., Abelmann, L. & S. M. Khalil, I.https://doi.org/10.1088/1748-605X/ac8b4b
Research profiles
Courses academic year 2024/2025
Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses academic year 2023/2024
In the press
- American Institute of Physics | Using untethered microrobots to remove blood clots
- De Ingenieur | Magnetic robots remove blood clots
- Scientias | Dutch develop revolutionary microrobots that could potentially save many lives
- UT News | Magnetics microrobots remove blood clots from sheep iliac artery
- FOX NEWS | How tiny corkscrew robots could save lives by breaking up blood clots
- RTL News | Robot through your bloodsteam
- RD.nl | Dutch researchers let robot swim through blood vessel
- Oost | Robot for clearing blood clots
- ChemistryWorld | Suit of iron turns sperm cells into spermbots
- Innovation Origins | Wireless millirobots successfully navigate blood vessels, piercing blood clots along the way
- Innovation Origins | Millirobots on an adventure: wireless robots navigate arteries
- Kennispark Twente | Millirobots on an adventure: wireless millirobots successfully navigate arteries
- New Atlas | Clot-busting "millirobots" corkscrew their way through blood vessels
- NPO Radio | Michiel Warle - Interview Humberto
- Radboudumc | Magnetics microrobots remove blood clots from sheep iliac artery
- ICRA18 Finalist of Medical Robot Paper: Mechanical Rubbing of Blood Clots using Helical Robots
News on utwente.nl
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University of Twente
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Netherlands
University of Twente
Carré C3605
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Netherlands
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