Technohal

prof.dr. J. Hofmeijer (Jeannette)

Full Professor
TNW-BIS-CNPH
Technohal 3381
j.hofmeijer@utwente.nl
+31534894835
Business card

General information

Jeannette Hofmeijer studied Medicine and Philosophy at Radboud University Nijmegen. She received her master’s degree in Medicine cum laude in 1998. She was trained as a neurologist and as intensive care physician at University Medical Center Utrecht. Meanwhile, she obtained a PhD at the Biomedical MR Imaging and Spectroscopy Group of Utrecht University on the topic of edema formation in cerebral ischemia (2007). Since 2008, she combines her work as a vascular neurologist in Rijnstate Hospital (Arnhem) with a research and teaching position at University of Twente. She was appointed professor of Translational Neurophysiology in 2019.

Research interests

Hofmeijer studies the effects of ischemia on the brain. Cerebral ischemia is of particular interest in patients with brain infarction or after cardiac arrest. These conditions are leading causes of disability, worldwide. Apart from acute reperfusion therapies, effective treatments to promote cerebral recovery are unavailable.

Hofmeijer exploits her dual position at hospital and UT to combine clinical with fundamental research on cerebral ischemia. She believes that the combination of systematic observation in patients and targeted experimentation holds strong potential to provide new, clinically relevant, pathophysiological insights, that assist in the development of novel diagnostics or treatments. For example, by combining clinical EEG registrations and experimental in vitro studies, her research group positioned synaptic failure as a key pathological mechanisms after cardiac arrest and brain infarction. Neuronal stimulation effectively improved neuronal recovery under experimental in vitro conditions and is currently investigated in phase 2 and 3 clinical trials in comatose patients after cardiac arrest.

Hofmeijer established the Dutch-Belgian TELSTAR consortium and is principle investigator of various state of the art multicenter clinical trials to test new treatments and diagnostics in comatose patients after cardiac arrest (amongst other www.telstartrial.nl, www.grecotrial.nl). Her research is supported by grants from ZonMW, NWO, Hartstichting, and Hersenstichting. She sits on national guideline committees for treatment of ischemic stroke and coma after cardiac arrest and chairs the jury of the two-yearly science award of the Netherlands Neurovascular Society.

Expertise

  • Medicine and Dentistry

    • Patient
    • Therapeutic Procedure
    • Brain Ischemia
    • Apoplexy
    • Heart Arrest
    • Inpatient

  • Neuroscience

    • Ischemic Stroke
    • Stroke

Organisations

Ancillary activities

  • Rijnstate hospitalneurologist

Publications

2026

Postictal agitation is associated with brain-wide postictal microstructural changes after electroconvulsive therapy-induced seizures (2026)Brain stimulation, 19(2). Article 103031. Verdijk, J. P. A. J., van Dijk-Schouten, T. A. L., Pottkämper, J. C. M., van de Mortel, L. A., ten Doesschate, F., Stuiver, S., Chamberland, M., Norris, D. G., van Putten, M. J. A. M., Hofmeijer, J., van Wingen, G. A. & van Waarde, J. A.https://doi.org/10.1016/j.brs.2026.103031Serum biomarkers of postanoxic encephalopathy in relation to ghrelin treatment.: A secondary analysis of the GRECO trial (2026)Resuscitation. Article 110980 (Accepted/In press). Omes, Q. P. M., Nutma, S., Beishuizen, A., Filius, P. M. G., van der Worp, H. B., Foudraine, N. A., Krabbe, J. G., Strate, I. A., van Putten, M. J. A. M., Hofmeijer, J., Nutma, S., Beishuizen, A., van den Bergh, W. M., Foudraine, N. A., Le Feber, J., Filius, P. M. G., Cornet, A. D., van der Palen, J., van Putten, M. J. A. M. & Hofmeijer, J.https://doi.org/10.1016/j.resuscitation.2026.110980Integrating cross-sectional imaging data into functional outcome prediction models for acute ischemic stroke of the anterior circulation (2026)Neuroscience Informatics, 6(1). Article 100260 (E-pub ahead of print/First online). te Nijenhuis, F., van der Sluijs, M., van Doormaal, P. J., van Zwam, W., Hofmeijer, J., Zhang, X., Cornelissen, S., Ruijters, D., Su, R. & van Walsum, T.https://doi.org/10.1016/j.neuri.2026.100260Association of anesthesia strategies with outcomes in endovascular treatment for distal and medium vessel occlusions: A propensity score-matched analysis of the MR CLEAN registry and meta-analysis (2026)European stroke journal, 11(1). Article 23969873251352406. Doheim, M. F., Knapen, R. R. M. M., Dippel, D. W. J., Staals, J., Hofmeijer, J., van Es, A. C. G. M., Coutinho, J. M., van der Leij, C., Nogueira, R. G., van Oostenbrugge, R. J. & van Zwam, W. H.https://doi.org/10.1177/23969873251352406Hyperglycaemia does not modify the efficacy of endovascular therapy in the late time window (6–24 hours) (2026)International journal of stroke, 21(1), 138-145. Kersten, C. J., Zandbergen, A. A. M., Olthuis, S. G. H., van Zwam, W. H., Hofmeijer, J., Emmer, B. J., Hoving, J. W., van Oostenbrugge, R. J. & den Hertog, H. M.https://doi.org/10.1177/17474930251358824Perfusion Angiography in Reperfused Patients with Ischemic Stroke: Differentiating between Favorable and Unfavorable Outcome (2026)American journal of neuroradiology, 47(1), 59-65. van der Sluijs, P. M., Su, R., Schoon, B. A., van de Graaf, R. A., Cornelissen, S. A. P., van Es, A. C. G. M., van Doormaal, P. J., Hofmeijer, J., Roozenbeek, B., van Zwam, W. H., van der Lugt, A. & van Walsum, T.https://doi.org/10.3174/ajnr.A8936Temporal dynamics of electroconvulsive therapy induced seizures (2026)Clinical neurophysiology, 181. Article 2111439. Stuiver, S., Tewarie, P. K. B., Pottkämper, J. C. M., Verdijk, J. P. A. J., van Putten, M. J. A. M., Hofmeijer, J. & van Waarde, J. A.https://doi.org/10.1016/j.clinph.2025.2111439

2025

National trends in patient characteristics, interventional techniques and outcomes of endovascular treatment for acute ischaemic stroke: Final results of the MR CLEAN Registry (2014–2018) (2025)European stroke journal, 10(4), 1268-1280. Hinsenveld, W. H., Brouwer, J., den Hartog, S. J., Bruggeman, A., Kappelhof, M., Jansen, I. G. H., Mulder, M. J. H. L., Compagne, K. C. J., Goldhoorn, R. J. B., Lingsma, H., Lycklama à Nijeholt, G., Gons, R. A. R., Yo, L. F. S., Uyttenboogaart, M., Bokkers, R., van der Worp, B. H., Lo, R. H., Schonewille, W., Brouwers, P., … van Oostenbrugge, R.https://doi.org/10.1177/23969873251334271Does sex matter in neurons’ response to hypoxic stress? (2025)Journal of Stroke & Cerebrovascular Diseases, 34(11). Article 108444. Voogd, E. J. H. F., Levers, M. R., Hofmeijer, J., Frega, M. & van Putten, M. J. A. M.https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108444Early EEG and serum biomarkers for prognostication after cardiac arrest (2025)Resuscitation Plus, 26. Article 101154. Strate, I. A., Krabbe, J. G., Nutma, S., Beishuizen, A., Vermeijden, W. J., Kornips, F. H. M., Foudraine, N. A., Hofmeijer, J. & van Putten, M. J. A. M.https://doi.org/10.1016/j.resplu.2025.101154

Research profiles

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

Address

University of Twente

Technohal (building no. 18), room 3381
Hallenweg 5
7522 NH Enschede
Netherlands

Navigate to location

Organisations

Scan the QR code or
Download vCard