Welcome...

dr.ir. J. Rouwkema (Jeroen)

Associate Professor

About Me

Jeroen Rouwkema is currently an Associate Professor in the Department of Biomechanical Engineering at the University of Twente. Jeroen received his doctoral degree from the University of Twente under the supervision of prof. Clemens van Blitterswijk. Prior to this, he worked 6 months in the lab of prof. Robert (Bob) Langer at MIT, USA. Between 2014 and 2015 he was also appointed as a Visiting Researcher at Harvard Medical School, USA, in the group of Prof. Ali Khademhosseini.

His expertise and interests are tissue engineering, vascularization, and the role that biomechanical signals play in these processes. He has published in multiple high-impact journals, including Nature Biotechnology (IF 41.5), Advanced Materials (IF19.0), TRENDS in Biotechnology (4x, IF 12.0), and PNAS (2x, IF 9.7). He has directed approximately € 3 million in research funding.

Jeroen has received a VENI fellowship from NWO, as well as an International Outgoing Fellowship, which is part of the Marie Skłodowska-Curie actions of the European Commission. In 2017 he received a European Research Council (ERC) Advanced grant and in 2019 an ERC Proof of Concept grant. In 2017 he also received the TERMIS EU Robert Brown Early Career Principal Investigator Award.

For more info about Jeroen Rouwkema on the 'Featured Scientists' page, click below:

Expertise

Engineering & Materials Science
Biomaterials
Hydrogels
Intercellular Signaling Peptides And Proteins
Scaffolds
Tissue
Tissue Engineering
Agriculture & Biology
Blood Vessels
Medicine & Life Sciences
Tissue Engineering

Research

Dr. Rouwkema focuses on tuning the local mechanical and chemical micro-environment in order to control development and organization of vascularized engineered tissues. Adding a vascular network to an engineered tissue is a promising method to enhance tissue integration and survival after implantation. The engineered vascular network can connect to the vasculature of the patient, resulting in a faster perfusion with blood and therefore a better supply of nutrients and oxygen.

For more information see the following website: http://www.vascularizationlab.com/ 

Publications

Recent
Padmanaban, P. , Rouwkema, J., Kerstholt, M., & Merks , R. M. H. (2022). Simulate before you stimulate: predictive cell-based models for tissue engineering applications. 121-121. Poster session presented at EMBO Workshop Building networks: engineering in vascular biology, Barcelona , Netherlands.
Trikalitis, V. D. , Stein, F. , Kandar, A. K., Rangel, V., Perea Paizal, J., Stimac, M. , & Rouwkema, J. (2021). Motile Bioactive Embedding Baths based on Biomaterial Hydrogel Particles. Poster session presented at 6th world congress of the Tissue Engineering and Regenerative Medicine International Society, TERMIS 2021, Maastricht , Netherlands.
Mohanty, S. , Zhang, J., McNeill, J. M., Kuenen, T., Linde, F. P. , Rouwkema, J. , & Misra, S. (2021). Acoustically-actuated bubble-powered rotational micro-propellers. Sensors and Actuators B: Chemical, 347, [130589]. https://doi.org/10.1016/j.snb.2021.130589
Silva, A. L., Babo, P. S., Rodrigues, M. T., Gonçalves, A. I., Novoa-Carballal, R., Pires, R. A. , Rouwkema, J., Reis, R. L., & Gomes, M. E. (2021). Hyaluronic Acid Oligomer Immobilization as an Angiogenic Trigger for the Neovascularization of TE Constructs. ACS Applied Bio Materials, 4(8), 6023-6035. https://doi.org/10.1021/acsabm.1c00291
Vroemen, P. A. M. M. , Sinha, R., Gamardo, A. S. , Rouwkema, J. , Moroni, L., Webers, C. A. B., & Gorgels, T. G. M. F. (2020). The effects of pressure and strain on neuronal cells. Acta Ophthalmologica, 98(S264), 20-20. https://doi.org/10.1111/aos.14387
Rana, D. , Trikalitis, V. D., Rangel, V. R. , Kandar, A. K. , & Rouwkema, J. (Accepted/In press). Patterning Self-Organizing Microvascular Networks within Engineered Matrices. Abstract from 29th Annual Meeting Netherlands Society for Biomaterials and Tissue Engineering, Netherlands.
Rana, D. , Trikalitis, V. D., Rangel, V. R. , Salehi Nik, N. , & Rouwkema, J. (Accepted/In press). Engineering Patterned Aptamer-Functionalized Hydrogels for Controlling Vascularization. Abstract from 11th World Biomaterials Congress, WBC 2020.

UT Research Information System

Google Scholar Link

Contact Details

Visiting Address

University of Twente
Faculty of Engineering Technology
Horst Complex (building no. 20), room W104
De Horst 2
7522LW  Enschede
The Netherlands

Navigate to location

Mailing Address

University of Twente
Faculty of Engineering Technology
Horst Complex  W104
P.O. Box 217
7500 AE Enschede
The Netherlands