The goal of the VESCEL project is to produce working vascular systems from human induced pluripotent stem cells. The vessels on a chip will be a platform for both drug screening and the study of vascular disease in a personalized system. The resulting devises should help reduce the need for animal testing and clinical studies.
My part in this project is the development of 3D printed vascular networks. After being cultured with endothelial cells, the printed structures will mimic the capillary networks found in natural tissues. This technique will not only provide a platform for studying the vascular system, but will produce fine structures which can support higher cell densities than currently possible in three dimensional tissue analogs.