dr. J.C.H. Leijten (Jeroen)

Associate Professor
TNW-BET-DBE
jeroen.leijten@utwente.nl
+31534894576
Business card

As a biomedical microtechnologist, I am passionate about integrating promising upcoming micromaterials and (micro)technologies into the fields of medical biology, cell-based therapies and clinical diagnostics. After my PhD in Tissue Engineering at University of Twente, I performed postdocs at KU Leuven and Harvard-MIT, where I became subgroup leader, after which I accepted a Tenure track position at University of Twente. I have a Visible research track, strong expertise and experimental background in: I) tissue engineering, II) microfluidic technology, III) organs-on-a-chip, IV) (stem) cell biology; and V) biomimetic biomaterials. This has led to numerous papers in high-ranked journals including Cell Stem Cell, Nature Communications, Small, Advanced Functional Materials, and PNAS. I have had the honour to have been awarded with Veni, Vidi, and ERC Starting grants as well as multiple early career and presentation awards.  

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Expertise

  • Medicine and Dentistry

    • Cartilage
    • Cells
    • Mesenchymal Stem Cell
    • Chondrocyte
    • Tissues
    • Osteoarthritis
    • Differentiation

  • Biochemistry, Genetics and Molecular Biology

    • Stem Cell

Organisations

Publications

2025

High-Throughput Single-Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC) (2025)Advanced materials, 37(6). Article 2415981. Meteling, M., Johnbosco, C., Wolfel, A., Conceição, F., Govindaraj, K., Teixeira, L. M. & Leijten, J.https://doi.org/10.1002/adma.202415981Synergistic effect of Hypoxic Conditioning and Cell-Tethering Colloidal Gels enhanced Productivity of MSC Paracrine Factors and Accelerated Vessel Regeneration (2025)Advanced materials, 37(3). Article 2408488. Lee, M. C., Lee, J. S., Kim, S., Jamaiyar, A., Wu, W., Gonzalez, M. L., Durán, T. C. A., Madrigal-Salazar, A. D., Bassous, N., Carvalho, V., Choi, C., Kim, D. S., Seo, J. W., Rodrigues, N., Teixeira, S. F. C. F., Alkhateeb, A. F., Soto, J. A. L., Hussain, M. A., Leijten, J., … Shin, S. R.https://doi.org/10.1002/adma.202408488Effect of fluid flow-induced shear stress on the behavior of synovial fibroblasts in a bioinspired synovium-on-chip model (2025)Journal of Cartilage & Joint Preservation. Article 100233 (E-pub ahead of print/First online). Piluso, S., Li, Y., Texeira, L. M., Padmanaban, P., Rouwkema, J., Leijten, J., van Weeren, R., Karperien, M. & Malda, J.https://doi.org/10.1016/j.jcjp.2025.100233Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration (2025)Pharmaceutics, 17(1). Article 64. Gomes, F. L., Conceição, F., Teixeira, L. M., Leijten, J. & Jonkheijm, P.https://doi.org/10.3390/pharmaceutics17010064

2024

Covalent On-Cell Conjugation of Biomaterials Through Oxidative Phenolic Coupling Regulates Stem Cell Fate via Intracellular Biophysical Programming (2024)Advanced functional materials. Article 2418963 (E-pub ahead of print/First online). Johnbosco, C., Becker, M., Willemen, N., Meteling, M., Govindaraj, K., Kamperman, T. & Leijten, J.https://doi.org/10.1002/adfm.202418963Upscaling Osteoclast Generation by Enhancing Macrophage Aggregation Using Hollow Microgels (2024)Small, 20(46). Article 2403272. Husch, J. F. A., Araújo-Gomes, N., Willemen, N. G. A., Cofiño-Fabrés, C., van Creij, N., Passier, R., Leijten, J. & van den Beucken, J. J. J. P.https://doi.org/10.1002/smll.202403272Microfluidic Generation of Thin-Shelled Polyethylene Glycol-Tyramine Microgels for Non-Invasive Delivery of Immunoprotected β-Cells (2024)Advanced healthcare materials, 13(25). Article 2301552. Araújo-Gomes, N., Zoetebier-Liszka, B., van Loo, B., Becker, M., Nijhuis, S., Smink, A. M., de Haan, B. J., de Vos, P., Karperien, M. & Leijten, J.https://doi.org/10.1002/adhm.202301552Injectable Self-Oxygenating Cardio-Protective and Tissue Adhesive Silk-Based Hydrogel for Alleviating Ischemia After Mi Injury (2024)Small, 20(32). Article 2312261. Hassan, S., Rezaei, Z., Luna, E., Yilmaz-Aykut, D., Lee, M. C., Perea, A. M., Jamaiyar, A., Bassous, N., Hirano, M., Tourk, F. M., Choi, C., Becker, M., Yazdi, I., Fan, K., Avila-Ramirez, A. E., Ge, D., Abdi, R., Fisch, S., Leijten, J., … Shin, S. R.https://doi.org/10.1002/smll.202312261Photoannealing of Microtissues Creates High-Density Capillary Network Containing Living Matter in a Volumetric-Independent Manner (2024)Advanced materials, 36(28). Article 2308949. Schot, M., Becker, M., Paggi, C. A., Gomes, F., Koch, T., Gensheimer, T., Johnbosco, C., Nogueira, L. P., van der Meer, A., Carlson, A., Haugen, H. & Leijten, J.https://doi.org/10.1002/adma.202308949Photoannealing of Microtissues Creates High-Density Capillary Network Containing Living Matter in a Volumetric-Independent Manner (Adv. Mater. 28/2024) (2024)Advanced materials, 36(28). Article 2470219. Schot, M., Becker, M., Paggi, C. A., Gomes, F., Koch, T., Gensheimer, T., Johnbosco, C., Nogueira, L. P., van der Meer, A., Carlson, A., Haugen, H. & Leijten, J.https://doi.org/10.1002/adma.202470219

Research profiles

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