dr. J.C.H. Leijten (Jeroen)

Associate Professor
TNW-BET-DBE
jeroen.leijten@utwente.nl
+31534894576
Business card

As a biomedical microtechnologist, I am passionate about integrating promising upcoming micromaterials and (micro)technologies into the fields of medical biology, cell-based therapies and clinical diagnostics. After my PhD in Tissue Engineering at University of Twente, I performed postdocs at KU Leuven and Harvard-MIT, where I became subgroup leader, after which I accepted a Tenure track position at University of Twente. I have a Visible research track, strong expertise and experimental background in: I) tissue engineering, II) microfluidic technology, III) organs-on-a-chip, IV) (stem) cell biology; and V) biomimetic biomaterials. This has led to numerous papers in high-ranked journals including Cell Stem Cell, Nature Communications, Small, Advanced Functional Materials, and PNAS. I have had the honour to have been awarded with Veni, Vidi, and ERC Starting grants as well as multiple early career and presentation awards.  

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Expertise

  • Medicine and Dentistry

    • Cartilage
    • Cells
    • Mesenchymal Stem Cell
    • Chondrocyte
    • Tissues
    • Osteoarthritis

  • Biochemistry, Genetics and Molecular Biology

    • Stem Cell

  • Chemistry

    • Microfluidics

Organisations

Publications

2024
Towards single-cell bioprinting: micropatterning tools for organ-on-chip developmentTrends in biotechnology, 42(6), 739-759 (E-pub ahead of print/First online). Bosmans, C., Ginés Rodriguez, N., Karperien, M., Malda, J., Moreira Teixeira, L., Levato, R. & Leijten, J.https://doi.org/10.1016/j.tibtech.2023.11.014An oxygenating colloidal bioink for the engineering of biomimetic tissue constructsBio-Design and Manufacturing, 7(3), 240-261 (Accepted/In press). Jeong, S. H., Hiemstra, J., Blokzijl, P. V., Damian-Ferrara, R., dos Santos, D. M., da Fonseca, J. H. L., Kang, M. H., Kim, J., Yilmaz-Aykut, D., Cham-Pérez, M. L. L., Leijten, J. & Shin, S. R.https://doi.org/10.1007/s42242-024-00281-7Osmolarity-Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis PathologyAdvanced science, 11(11), Article 2306722. Govindaraj, K., Meteling, M., van Rooij, J., Becker, M., van Wijnen, A. J., van den Beucken, J. J. J. P., Ramos, Y. F. M., van Meurs, J., Post, J. N. & Leijten, J.https://doi.org/10.1002/advs.202306722Scalable production of 3D microtissues using novel microfluidic technologies. University of Twente. van Loo, S. R.https://doi.org/10.3990/1.9789464960372Engineering Synthetic Erythrocytes as Next-Generation Blood SubstitutesAdvanced functional materials (E-pub ahead of print/First online). Gomes, F. L., Jeong, S. H., Shin, S. R., Leijten, J. & Jonkheijm, P.https://doi.org/10.1002/adfm.202315879Injectable Self-Oxygenating Cardio-Protective and Tissue Adhesive Silk-Based Hydrogel for Alleviating Ischemia After Mi InjurySmall (Accepted/In press). Hassan, S., Rezaei, Z., Luna, E., Yilmaz-Aykut, D., Lee, M. C., Perea, A. M., Jamaiyar, A., Bassous, N., Hirano, M., Tourk, F. M., Choi, C., Becker, M., Yazdi, I., Fan, K., Avila-Ramirez, A. E., Ge, D., Abdi, R., Fisch, S., Leijten, J., … Shin, S. R.https://doi.org/10.1002/smll.202312261
2023
Photoannealing of Microtissues Creates High-Density Capillary Network Containing Living Matter in a Volumetric-Independent MannerAdvanced materials, Article 2308949 (E-pub ahead of print/First online). Schot, M., Becker, M., Paggi, C. A., Gomes, F., Koch, T., Gensheimer, T., Johnbosco, C., Nogueira, L. P., van der Meer, A., Carlson, A., Haugen, H. & Leijten, J.https://doi.org/10.1002/adma.202308949Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsulesNature communications, 14, Article 6685. van Loo, S. R., ten Den, S. A., Araújo-Gomes, N., de Jong, V., Snabel, R., Schot, M. R., Rivera Arbelaez, J. M., Veenstra, G. J., Passier, R., Kamperman, T. & Leijten, J.https://doi.org/10.1038/s41467-023-42297-0Single-Step Biofabrication of In Situ Spheroid-Forming Compartmentalized Hydrogel for Clinical-Sized Cartilage Tissue FormationAdvanced healthcare materials, 12(27), Article 2300095. van Loo, B., Schot, M., Gurian, M., Kamperman, T. & Leijten, J.https://doi.org/10.1002/adhm.202300095Bioluminescence imaging on-chip platforms for non-invasive high-content bioimagingBiosensors and Bioelectronics, 237, Article 115510. Araújo-Gomes, N., Zambito, G., Johnbosco, C., Calejo, I., Leijten, J., Löwik, C., Karperien, M., Mezzanotte, L. & Teixeira, L. M.https://doi.org/10.1016/j.bios.2023.115510

Research profiles

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