dr. J.C.H. Leijten (Jeroen)

As a biomedical microtechnologist, I am passionate about integrating promising upcoming micromaterials and (micro)technologies into the fields of medical biology, cell-based therapies and clinical diagnostics. After my PhD in Tissue Engineering at University of Twente, I performed postdocs at KU Leuven and Harvard-MIT, where I became subgroup leader, after which I accepted a Tenure track position at University of Twente. I have a Visible research track, strong expertise and experimental background in: I) tissue engineering, II) microfluidic technology, III) organs-on-a-chip, IV) (stem) cell biology; and V) biomimetic biomaterials. This has led to numerous papers in high-ranked journals including Cell Stem Cell, Nature Communications, Small, Advanced Functional Materials, and PNAS. I have had the honour to have been awarded with Veni, Vidi, and ERC Starting grants as well as multiple early career and presentation awards.

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Engineering & Materials Science

# Cartilage
# Hydrogels
# Stem Cells
# Tissue

Chemistry

# Biomaterial
# Hydrogel

Medicine & Life Sciences

# Chondrocytes
# Hydrogels

Faculty of Science and Technology (TNW), Developmental BioEngineering (DBE)

Schot, M. , Araújo-Gomes, N., van Loo, B. , Kamperman, T. , & Leijten, J. (2023). Scalable fabrication, compartmentalization and applications of living microtissues. Bioactive Materials, 19, 392-405. https://doi.org/10.1016/j.bioactmat.2022.04.005

Elkhoury, K., Chen, M., Koçak, P., Enciso-Martínez, E., Bassous, N. J., Lee, M. C., Byambaa, B., Rezaei, Z., Li, Y., Ubina López, M. E. , Gurian, M., Sobahi, N., Hussain, M. A., Sanchez-Gonzalez, L. , Leijten, J. , Hassan, S., Arab-Tehrany, E., Ward, J. E., & Ryon Shin, S. (2022). Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA. Biofabrication, 14(4), [045008]. https://doi.org/10.1088/1758-5090/ac8621

Kajtez, J., Wesseler, M. F., Birtele, M., Khorasgani, F. R., Rylander Ottosson, D., Heiskanen, A. , Kamperman, T. , Leijten, J., Martínez-Serrano, A., Larsen, N. B., Angelini, T. E., Parmar, M., Lind, J. U., & Emnéus, J. (2022). Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs. Advanced science, 9(25), [2201392]. https://doi.org/10.1002/advs.202201392

Govindaraj, K. , Meteling, M. A. W. , Becker, M. L. , Post, J. N. , & Leijten, J. (2022). Osmolarity-Induced altered intracellular molecular crowding drives osteoarthritis pathology. Osteoarthritis and cartilage, 30(Suppl. 1), S24-S25. https://doi.org/10.1016/j.joca.2022.02.021

Willemen, N. G. A. , Hassan, S. , Gurian, M., Jasso-Salazar, M. F., Fan, K., Wang, H. , Becker, M. , Allijn, I. E., Bal-Öztürk, A. , Leijten, J., & Ryon Shin, S. (2022). Enzyme-Mediated Alleviation of Peroxide Toxicity in Self-Oxygenating Biomaterials. Advanced healthcare materials, 11(13), [2102697]. https://doi.org/10.1002/adhm.202102697

Zhong, L. , Koerselman, M. , Karbaat, L. , Kamperman, T. , Leijten, J. , Zoetebier, B. , & Karperien, M. (2021). Injectable hydrogels functionalized with antibody fragments as intra-articular cytokine sinks neutralizing pro-catabolic cytokines. Osteoarthritis and cartilage, 29(Suppl. 1), S50-S50. https://doi.org/10.1016/j.joca.2021.02.073

Joglekar, M. M., Slebos, D-J. , Leijten, J., Burgess, J. K., & Pouwels, S. D. (2021). Crosslink bio-adhesives for bronchoscopic lung volume reduction: current status and future direction. European Respiratory Review, 30(162), [210142]. https://doi.org/10.1183/16000617.0142-2021

Kajtez, J., Wessler, M. F., Birtele, M., Khorasgani, F. R., Rylander Ottosson, D., Heiskanen, A. , Kamperman, T. , Leijten, J., Martínez-Serrano, A., Larsen, N. B., Angelini, T. E., Parmar, M., Lind, J. U., & Emnéus, J. (2021). Embedded 3D printing in self-healing annealable composites for functional patterning of human neural constructs. bioRxiv. https://doi.org/10.1101/2021.08.04.455135

Farzin, A. , Hassan, S. , Moreira Teixeira, L. S. , Gurian, M. , Crispim, J. F., Manhas, V., Carlier, A., Bae, H., Geris, L., Noshadi, I., Ryon Shin, S. , & Leijten, J. (2021). Self-Oxygenation of Tissues Orchestrates Full-Thickness Vascularization of Living Implants. Advanced functional materials, 31(42), [2100850]. https://doi.org/10.1002/adfm.202100850

Kamperman, T. , Henke, S. , Crispim, J. F. , Willemen, N. G. A. , Dijkstra, P. J. , Lee, W. , Offerhaus, H. L., Neubauer, M., Smink, A. M., de Vos, P., de Haan, B. J. , Karperien, M., Ryon Shin, S. , & Leijten, J. (2021). Tethering Cells via Enzymatic Oxidative Crosslinking Enables Mechanotransduction in Non-Cell-Adhesive Materials. Advanced materials, 33(42), [2102660]. https://doi.org/10.1002/adma.202102660

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Bachelor

Biomedische Technologie

Master

Biomedical Engineering

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.