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Lejla currently holds the position of Associate Professor at the Department of Magnetic Detection and Imaging. Her expertise lies in the fields of medical imaging, computer vision, medical devices, and laparoscopy, as evidenced by her (co-)authorship of over 70 publications (excluding conference abstracts).
Lejla pursued her studies in Electrical Engineering at Delft University of Technology. Under the guidance of Prof. Babuska , she successfully completed her undergraduate program focusing on fuzzy clustering of medical signals. She also worked alongside Dr. ir. van Wijk van Brievingh, Prof. Ince , and Prof. Lelieveldt exploring the analysis of colonoscopy images. In 2013 she obtained het PhD from Erasmus Universiteit Rotterdam (Biomedical imaging Group Rotterdam ) supervised by Prof. Niessen . Her research in this period encompassed a wide range of methods for assessing cancer treatment outcomes using pre-clinical and clinical data. Her doctoral thesis, titled ‘Quantification of tumour heterogeneity in MRI ’, was defended within two graduate schools: Advanced School for Computing and Imaging and Molecular Medicine .
Throughout her academic journey, Lejla has held research fellowships at esteemed institutions, including Leiden University Medical Center (Division of Image Processing ), Academic Medical Center University of Amsterdam (Experimental Anaesthesiology), Engineering Science at the University of Oxford (Robotics Research Group, led by Sir. Brady ), Texas A&M University at Qatar (Department of Electrical and Computer Engineering ). Additionally, she served as a scientific researcher and project leader at TNO , a renowned Dutch contract research institute. In 2019, she assumed the role of Assistant Professor at the Department of Magnetic Detection and Imaging at the University of Twente .
Expertise Biochemistry, Genetics and Molecular Biology Magnetic Resonance Imaging Magnetism Iron Contrast Medicine and Dentistry Patient Tissues Magnetic Nanoparticle Lymph Node Organisations Lejla currently holds the position of Associate Professor at the Department of Magnetic Detection and Imaging. Her expertise lies in the fields of medical imaging, computer vision, medical devices, and laparoscopy, as evidenced by her (co-)authorship of over 70 publications (excluding conference abstracts).
Publications Jump to: 2024 | 2023 | 2022 | 2021
Engineered SPIONs functionalized with endothelin a receptor antagonist ameliorate liver fibrosis by inhibiting hepatic stellate cell activation (2024) Bioactive Materials, 39 , 406-426. ten Hove, M., Smyris, A., Booijink, R., Wachsmuth, L., Hansen, U., Alic, L. , Faber, C., Hӧltke, C. & Bansal, R.https://doi.org/10.1016/j.bioactmat.2024.05.034 Sentinel Lymph Node Mapping in Prostate Cancer: Magnetic Route (2024) JU Open Plus, 2 (8). Article e00081. Molenaar, L., Roelink, H. J. H., Stomps, S., Haken, B. t., Hulsbergen-van de Kaa, C., Braak, S., Veltman, J., Alic, L. & Broeders, I. A. M. J.https://doi.org/10.1097/JU9.0000000000000183 Amide proton transfer weighted imaging in pediatric neuro-oncology: initial experience (2024) NMR in biomedicine, 37 (6). Article e5122. Obdeijn, I. V., Wiegers, E. C., Alic, L. , Plasschaert, S. L. A., Kranendonk, M. E. G., Hoogduin, H. M., Klomp, D. W. J., Wijnen, J. P. & Lequin, M. H.https://doi.org/10.1002/nbm.5122 Technical innovations in breast cancer surgery (2024) [Thesis › PhD Thesis - Research external, graduation UT]. University of Twente. Christenhusz, A. https://doi.org/10.3990/1.9789036561556 Influence of Nanoparticle Coating on the Differential Magnetometry and Wireless Actuation of Biohybrid Microrobots (2023) In 2023 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) (pp. 2653-2658). IEEE. Magdanz, V., Cumming, J. R., Salamzadeh, S., Tesselaar, S., Alic, L. , Abelmann, L. & S.M. Khalil, I. https://doi.org/10.1109/IROS55552.2023.10341258 Performance of a Nonlinear Magnetic Handheld Probe for Intraoperative Sentinel Lymph Node Detection: A Phantom Study (2023) Annals of surgical oncology, 30 (13), 8735-8742. Nieuwenhuis, E. R., Mir, N., Horstman-van de Loosdrecht, M. M., Meeuwis, A. P. W., de Bakker, M. G. J., Scheenen, T. W. J. & Alic, L. https://doi.org/10.1245/s10434-023-14166-z Recovery of dilute (bio-based) volatile fatty acids by adsorption with magnetic hyperthermal swing desorption (2023) Separation and purification technology, 323 . Article 124273. Elhami, V., Hempenius, M. A., Vancso, G. J., Krooshoop, E. J. G., Alic, L. , Qian, X., Jebur, M., Wickramasinghe, R. & Schuur, B.https://doi.org/10.1016/j.seppur.2023.124273 Look-up table for assessment of iron content in Magtrace® samples based on Sentimag® (2023) [Dataset Types › Dataset]. 4TU.Centre for Research Data. Salamzadeh, S., Christenhusz, A. & Alic, L. https://doi.org/10.4121/2ad11693-4d07-488f-936e-a3d4d9430ae0 Resolving power phantom for nanoparticles (2023) [Dataset Types › Dataset]. 4TU.Centre for Research Data. Alic, L. , Horstman - van de Loosdrecht, M. & Mocking-Nieuwenhuis, E. https://doi.org/10.4121/20193302 Radiofrequency localization of nonpalpable breast cancer in a multicentre prospective cohort study: feasibility, clinical acceptability, and safety (2023) Breast cancer research and treatment, 201 , 67-75. Christenhusz, A., den Dekker, B. M., van Dalen, T., Jongen, L., van der Schaaf, M. C., Alic, L. , ten Haken, B., Pijnappel, R. M. & Dassen, A. E.https://doi.org/10.1007/s10549-023-07006-x Differentiating between giant cell arteritis and atherosclerosis on [18 F]FDG-PET: An explainable machine learning approach (2023) In 2023 IEEE 36th International Symposium on Computer-Based Medical Systems (CBMS) (pp. 870-875) (Proceedings - IEEE Symposium on Computer-Based Medical Systems; Vol. 2023-June). IEEE. Vries, H. S., Van Praagh, G. D., Nienhuis, P. H., Bouhali, O., Slart, R. H. J. A. & Alic, L. https://doi.org/10.1109/CBMS58004.2023.00334 Differential Magnetometry: Selective Magnetometry for In Vivo Use (2023) [Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Waanders, S. https://doi.org/10.3990/1.9789036556934 Settings of DiffMag handheld probe for maximal detection depth aiming perioperative lymph node harvesting (2023) International Journal on Magnetic Particle Imaging, 9 (1, suppl. 1). Article 2303052. Salamzadeh, S., Krooshoop, H. J. G., ten Haken, B. & Alic, L. https://doi.org/10.18416/IJMPI.2023.2303052 Near-Infrared Spectral Similarity between Ex Vivo Porcine and In Vivo Human Tissue (2023) Life, 13 (2). Article 357. Vries, E. d., Alic, L. , Schols, R. M., Emanuel, K. S., Wieringa, F. P., Bouvy, N. D. & Tuijthof, G. J. M.https://doi.org/10.3390/life13020357 Intracerebral Hemorrhage Segmentation on Noncontrast Computed Tomography Using a Masked Loss Function U-Net Approach (2023) Journal of Computer Assisted Tomography, 47 (1), 93-101. Coorens, N. A., Lipman, K. G., Krishnam, S. P., Tan, C. O., Alic, L. & Gupta, R.https://doi.org/10.1097/RCT.0000000000001380 Excitation coil for sentinel lymph node harvesting: design, digital twin and prototype (2022) Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2022 , 4402-4406. Molenaar, L., Horstman-van de Loosdrecht, M. M., Krooshoop, H. J. G., Wesselink, R. J. H., Ten Haken, B., Broeders, I. A. M. J. & Alic, L. https://doi.org/10.1109/EMBC48229.2022.9871415 Quantification of Magnetic Nanoparticles in ex vivo Colorectal Lymph Nodes (2022) Nano LIFE, 12 (03). Article 2250006. Molenaar, L., Loosdrecht, M. M. H. v. d., Alic, L. , Baarlen, J. v., Meijerink, J. J. H. J., Haken, B. t., Broeders, I. A. M. J. & Lips, D. J.https://doi.org/10.1142/S1793984422500064 Magnetic identification of sentinel lymph nodes in the head and neck: Reaching leaves (2022) [Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Nieuwenhuis, E. R. https://doi.org/10.3990/1.9789036554114 Tuning Excitation Field Frequency for Magnetic Particle Sensing using Superparamagnetic Quantifier (2022) Journal of biomedical nanotechnology, 18 (8), 1994-2000. Horstman - van de Loosdrecht, M. M., Kahmann, T., Ludwig, F. & Alic, L. https://doi.org/10.1166/jbn.2022.3406 A Comprehensive Grading System for a Magnetic Sentinel Lymph Node Biopsy Procedure in Head and Neck Cancer Patients (2022) Cancers, 14 (3). Article 678. Nieuwenhuis, E. R., Kolenaar, B., Hof, J. J., Baarlen, J. v., van Bemmel, A. J. M., Christenhusz, A., Scheenen, T. W. J., ten Haken, B., de Bree, R. & Alic, L. https://doi.org/10.3390/cancers14030678 Breast MRI in patients after breast conserving surgery with sentinel node procedure using a superparamagnetic tracer (2022) European radiology experimental, 6 (1). Article 3. Christenhusz, A., Pouw, J. J., Simonis, F. F. J., Douek, M., Ahmed, M., Klaase, J. M., Dassen, A. E., Klazen, C. A. H., van der Schaaf, M. C., ten Haken, B. & Alic, L. https://doi.org/10.1186/s41747-021-00257-7 Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging (2022) International journal of computer assisted radiology and surgery, 17 (1), 211-218. Azargoshasb, S., Molenaar, L., Rosiello, G., Buckle, T., van Willigen, D. M., van de Loosdrecht, M. M., Welling, M. M., Alic, L. , van Leeuwen, F. W. B., Winter, A. & van Oosterom, M. N.https://doi.org/10.1007/s11548-021-02458-2 Changing iron content and excitation field: Comparative study of Synomag® nanoparticles (2022) International Journal on Magnetic Particle Imaging, 8 (1). Article 2203053. Alic, L. , Riahi, K., Horstman-van de Loosdrecht, M. M., Rietberg, M., Perez y Perez, J., Dijkstra, C. & ten Haken, B.https://doi.org/10.18416/ijmpi.2022.2203053 Laparoscopic Probe for Sentinel Lymph Node Harvesting using Magnetic Nanoparticles (2022) IEEE transactions on biomedical engineering, 69 (1), 286-293. van de Loosdrecht, M., Molenaar, L., Krooshoop, E., Haken, B. t., Meijerink, J., Alic, L. & Broeders, I. A. M. J.https://doi.org/10.1109/TBME.2021.3092437 Modelling of dynamic behaviour in magnetic nanoparticles (2021) Nanomaterials, 11 (12). Article 3396. Rietberg, M., Waanders, S., Horstman-Van de Loosdrecht, M. M., Wildeboer, R. R., Haken, B. T. & Alic, L. https://doi.org/10.3390/nano11123396 Research profiles Affiliated study programs Courses academic year 2024/2025 Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses academic year 2023/2024