dr. L.M. van Loon (Lex)

Assistant Professor
TNW-BIS-CRPH
l.m.vanloon@utwente.nl
+31534896917
Business card

I am an part-time assistant professor within the CRPH group and Technical Physician at the UMC Utrecht, with an interest in clinical decision support. Currently I work on challenges in acute care data analysis and prediction by using deterministic model combined with machine learning capabilities (physics informed machine learning -> towards a medical digital twin.

Interesed in doing an internship or want to collaborate: please reach out.

Expertise

  • Medicine and Dentistry

    • Septic Shock
    • Esmolol
    • Experimental Septic Shock
    • Heart Arrest
    • Mean Arterial Pressure

  • Pharmacology, Toxicology and Pharmaceutical Science

    • Lipopolysaccharide
    • Hypertensive Factor
    • Inflammation

Organisations

Publications

2024

Understanding the complexity of cardiogenic shock management: the added value of advanced computational modeling (2024)Current Opinion in Critical Care, 30(4), 340-343. Meuwese, C. L., van Loon, L. M. & Donker, D. W.https://doi.org/10.1097/MCC.0000000000001164Computational modeling of heart failure in microgravity transitions (2024)Frontiers in Physiology, 15. Article 1351985. Wilson, S. L., Schulte, K. M., Steins, A., Gruen, R. L., Tucker, E. M. & van Loon, L. M.https://doi.org/10.3389/fphys.2024.1351985

2020

Contribution of alarm noise to average sound pressure levels in the ICU: An observational cross-sectional study (2020)Intensive and Critical Care Nursing, 61. Article 102901. Vreman, J., van Loon, L. M., van den Biggelaar, W., van der Hoeven, J. G., Lemson, J. & van den Boogaard, M.https://doi.org/10.1016/j.iccn.2020.102901The inspiration hold maneuver is a reliable method to assess mean systemic filling pressure but its clinical value remains unclear (2020)Annals of Translational Medicine, 8(21). Article 1390. van Loon, L. M., Hoeven van der, H., Veltink, P. H. & Lemson, J.https://doi.org/10.21037/atm-20-3540

Research profiles

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Current PhD students
UMC Utrecht - Ruben Zoodsma
University of Amsterdam - Joeri van de Sande

Current Technical Medicine student rojects:
M3 - UMC Utrecht - Intensive Care - Kim van der Tak
Project title: Fluid Resuscitation and Vasopressor Therapy in Hemodynamic Unstable ICU Patients

M3 - UMC Utrecht - Intensive Care - Arno Fennema  
Project title:  Prognostic value of pulse pressure features in venoarterial extracorporeal membrane oxygenation weaning, a research proposal

M3 - UMC Utrecht - Cardioanesthesiology - Daan Imholz
Project title: Optimization of ex vivo lung perfusion using perfusion and ventilation modelling

M3 - WKZ / UMC Utrecht - Anesthesiology - Myrna van Veen
Project title: Cerebral Hemodynamics in Neonates During Congenital Heart Surgery.

Previous Technical Medicine student projects:
M3 - UMC Utrecht - Intensive Care - Kimmia Azampanah
Project title: A digital twin for cardiac monitoring in patients receiving venoarterial extracorporeal membrane oxygenation

M3 - UMC Utrecht - Intensive Care - Catharina Jansen
Project title: Predictive model for successful weaning in VA-ECMO treatment

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