I am an assistant professor within the CRPH group, with an interest in clinical decision support. Currently I work on challenges in acute care data analysis and prediction by using deterministic model combined with machine learning capabilities (physics informed machine learning -> towards a medical digital twin.

Expertise

  • Medicine and Dentistry

    • Septic Shock
    • Esmolol
    • Experimental Septic Shock
    • Heart Arrest
    • Mean Arterial Pressure
  • Pharmacology, Toxicology and Pharmaceutical Science

    • Lipopolysaccharide
    • Hypertensive Factor
    • Inflammation

Organisations

Publications

2024

Understanding the complexity of cardiogenic shock management: the added value of advanced computational modeling (2024)Current Opinion in Critical Care, 30(4), 340-343. Meuwese, C. L., van Loon, L. M. & Donker, D. W.https://doi.org/10.1097/MCC.0000000000001164Computational modeling of heart failure in microgravity transitions (2024)Frontiers in Physiology, 15. Article 1351985. Wilson, S. L., Schulte, K. M., Steins, A., Gruen, R. L., Tucker, E. M. & van Loon, L. M.https://doi.org/10.3389/fphys.2024.1351985

2020

Contribution of alarm noise to average sound pressure levels in the ICU: An observational cross-sectional study (2020)Intensive and Critical Care Nursing, 61. Article 102901. Vreman, J., van Loon, L. M., van den Biggelaar, W., van der Hoeven, J. G., Lemson, J. & van den Boogaard, M.https://doi.org/10.1016/j.iccn.2020.102901The inspiration hold maneuver is a reliable method to assess mean systemic filling pressure but its clinical value remains unclear (2020)Annals of Translational Medicine, 8(21). Article 1390. van Loon, L. M., Hoeven van der, H., Veltink, P. H. & Lemson, J.https://doi.org/10.21037/atm-20-3540The role of venous return in organ perfusion (2020)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. van Loon, L. M.https://doi.org/10.3990/1.9789036549462Effect of Vasopressors on the Macro- and Microcirculation during Systemic Inflammation in Humans in Vivo (2020)Shock, 53(2), 171-174. Van Loon, L. M., Stolk, R. F., Van Der Hoeven, J. G., Veltink, P. H., Pickkers, P., Lemson, J. & Kox, M.https://doi.org/10.1097/SHK.0000000000001357

2019

β-Blockade attenuates renal blood flow in experimental endotoxic shock by reducing perfusion pressure (2019)Physiological Reports, 7(23). Article e14301. van Loon, L. M., Rongen, G. A., van der Hoeven, J. G., Veltink, P. H. & Lemson, J.https://doi.org/10.14814/phy2.14301

Research profiles

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

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