Zilverling

dr. L.O. Bonino da Silva Santos MSc (Luiz)

Associate Professor
EEMCS-CS-SCS
Zilverling 2005
l.o.boninodasilvasantos@utwente.nl
+31534896403
Business card

I'm an Associate Professor at the Semantics, Cybersecurity and Services group at the University of Twente and at the BioSemantics group, in the department of Human Genetics at the Leiden University Medical Center.

My main research topics are the FAIR principles, semantic interoperability, ontology-driven conceptual modelling and intelligent systems design. Since 2014 I have been closely involved in designing and leading the implementation of a number of technologies and approaches to support the realisation of the FAIR principles.

Expertise

  • Computer Science

    • Ontology
    • Interoperability
    • User
    • Models
    • Metadata
    • Digital Object
    • Conceptual Model
    • Domains

Organisations

Together with my position at the University of Twente, I am also Associate Professor in the BioSemantics Group at the Leiden University Medica Center, in Leiden, the Netherlands.

Since 2014 I have been closely involved in the FAIR principles (findable, accessible, interoperable and reusable) movement. More specifically, I have participated in the research, design and development of a number of approaches and technologies to enable and/or facilitate the realisation of the FAIR principles such as FAIR metrics, FAIR Data Point, FAIRifier, FAIR Data Train and FAIR Digital Objects Framework.

Publications

Jump to: 2026 | 2025 | 2024

2026

Mapping the Pain: How Modelers Experience and Respond to Common Domain Modeling Frustrations (2026)In Enterprise Design, Operations, and Computing: 29th International Conference, EDOC 2025, Lisbon, Portugal, September 9–12, 2025, Revised Selected Papers (pp. 193-209) (Lecture Notes in Computer Science; Vol. 16213). Springer. Valle, I., Sales, T. P., Guerra, E., Daneva, M., da Silva Santos, L. O. B., Proper, H. & Guizzardi, G.https://doi.org/10.1007/978-3-032-15140-7_11

2025

ChatGPT as a Semantic Engineering Assistant: Lessons from Ontology Design in the Agricultural Biodiversity Domain (2025)Biodiversity Information Science and Standards, 9. Article e181272. Miranda Soares, F., Ferreira Pires, L., Bonino da Silva Santos, L. O., Pignatari Drucker, D., de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Botazzo Delbem, A. C. & Saraiva, A. M.https://doi.org/10.3897/biss.9.181272Business model innovation in a research ecosystem: the case of rare diseases (2025)International Journal of Organizational Analysis, 33(11), 4385-4418. Sánchez, M. d. C., Sarmiento-Suárez, R., Hooft, R. W. W., Moreau, C., Bietrix, F., Jervelund, C., Mejer, M., Kreiner, K., Haddad, T., Bonino da Silva Santos, L. O., Mimouni, Y., Rath, A., Posada de la Paz, M., Bermejo-Sánchez, E. & Julkowska, D.https://doi.org/10.1108/IJOA-06-2024-4588Taxonomy OWLizer: A Tool for Converting Taxonomic Data into OWL (2025)Biodiversity Information Science and Standards, 9. Soares, F., Saraiva, A., Ferreira Pires, L., Santos, L. & Drucker, D.https://doi.org/10.3897/biss.9.176413A Semantic Interoperability Framework for Data-Centric Applications in Agriculture (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Miranda Soares, F.https://doi.org/10.3990/1.9789036567626A Novel UX-Based Approach for Ontology Evaluation: Applying Tree Testing to the Agricultural Product Types Ontology (2025)IEEE Access, 13, 137986-138004. Article 11108173. Soares, F. M., Saraiva, A. M., Pires, L. F., Pignatari Drucker, D., Braghetto, K. R., Santos, L. O. B. d. S., de Abreu Moreira, D., Corrêa, F. E. & Botazzo Delbem, A. C.https://doi.org/10.1109/ACCESS.2025.3595447Unraveling the pain points of domain modeling (2025)Information and software technology, 183. Article 107736. Valle, I., Sales, T. P., Guerra, E., Daneva, M., Guizzardi, R., Bonino da Silva Santos, L. O., Proper, H. A. & Guizzardi, G.https://doi.org/10.1016/j.infsof.2025.107736Restructuring Knowledge Graphs with Conceptual Models: Implications for Machine Learning Predictions in Drug Repurposing (2025)In Lecture Notes in Computer Science (pp. 297-313). Article Chapter 17 (Advanced Information Systems Engineering; Vol. 15702). Springer. Bernabé, C., Zwart, R., Perdomo-Quinteiro, P., Jacobsen, A., Sales, T. P., Queralt-Rosinach, N., Wolstencroft, K., Santos, L. O. B. d. S., Mons, B. & Roos, M.https://doi.org/10.1007/978-3-031-94571-7_17The FAIR data point populator: collaborative FAIRification and population of FAIR data points (2025)BMC medical informatics and decision making, 25(Suppl 1). Article 211. Wijnbergen, D., Kaliyaperumal, R., Burger, K., Bonino da Silva Santos, L. O., Mons, B., Roos, M. & Mina, E.https://doi.org/10.1186/s12911-025-03022-7Exploring a Large Language Model for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development (2025)Data Intelligence, 7(2), 265-302. Soares, F. M., Saraiva, A. M., Pires, L. F., Santos, L. O. B. d. S., de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C.https://doi.org/10.3724/2096-7004.di.2025.0020Friend, Foe, or Target? Domain Models as Risk Deterrents, Risk Sources, and Assets at Risk (2025)In Research Challenges in Information Science: 19th International Conference, RCIS 2025, Seville, Spain, May 20–23, 2025, Proceedings, Part I (pp. 103-118) (Lecture Notes in Business Information Processing; Vol. 547 LNBIP). Springer. Valle, I., Sales, T. P., Guerra, E., Oliveira, Í., Guizzardi, R., Bonino da Silva Santos, L. O., Proper, H. & Guizzardi, G.https://doi.org/10.1007/978-3-031-92474-3_7GO-Plan: A goal-oriented method for FAIRification planning (2025)Information services & use, 45(1-2), 100-124. Bernabé, C., Valle, I., Prince Sales, T., Schultes, E., van Ulzen, N., Silva Souza, V. E., Jacobsen, A., Bonino da Silva Santos, L. O., Mons, B. & Roos, M.https://doi.org/10.1177/18758789251324008Exploring a Large Language Model for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development (2025)[Working paper › Preprint]. ArXiv.org. Soares, F. M., Saraiva, A. M., Pires, L. F., Santos, L. O. B. d. S., de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C.https://doi.org/10.48550/arXiv.2504.18651Restructuring knowledge graphs with conceptual models - Supplementary material (2025)[Dataset Types › Dataset]. Zenodo. Bernabé, C., Zwart, R., Perdomo-Quinteiro, P., Jacobsen, A., Prince Sales, T., Queralt-Rosinach, N., Wolstencroft, K., Bonino da Silva Santos, L. O., Mons, B. & Roos, M.https://doi.org/10.5281/zenodo.15163097FAIRDataTeam/FAIRDataPoint-client (2025)[Dataset Types › Dataset]. Zenodo. Slifka, J., Suchánek, M., Dennis & Bonino, L. O.https://doi.org/10.5281/zenodo.15020415Supporting Data for "Exploring ChatGPT-4 for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development" (2025)[Dataset Types › Dataset]. Zenodo. Soares, F., Saraiva, A. M., Ferreira Pires, L., Bonino, L., de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C.https://doi.org/10.5281/zenodo.12684940JRC FAIR Data Guidelines (2025)[Book/Report › Report]. Publications Office of the European Union. Lowenthal, H., Bonino da Silva Santos, L. O., Chiarelli, C., Cusinato, A., Ferigato, C., FRIIS-CHRISTENSEN, A., Kemper, T., Perrotta, D. & Wittwehr, C.https://doi.org/10.2760/5646214GO-Plan: A goal-oriented method for FAIRification planning - supplementary material (2025)[Dataset Types › Dataset]. Zenodo. Bernabé, C., Valle Sousa, I., Prince Sales, T., Schultes, E., van Ulzen, N., Silva Souza, V. E., Jacobsen, A., Bonino da Silva Santos, L. O., Barend, M. & Roos, M.https://doi.org/10.5281/zenodo.14780347FAIR Software as a Service: Combining tools to implement FAIR for clinical data platforms (2025)CEUR workshop proceedings, 3890, 208-209. Overkleeft, R., van Boom, S., Prud’Hommeaux, E., Burger, K., Fransen, J., Kappen, T., Bonino da Silva Santos, L., Kaliyaperumal, R. & Roos, M.

2024

Towards a Conceptual Model for FAIR Metadata Schemas (2024)In Companion Proceedings of the 43rd International Conference on Conceptual Modeling: ER Forum, Special Topics, Posters and Demos : Co-located with ER 2024 (pp. 42-55) (CEUR Workshop Proceedings; Vol. 3849). CEUR. Soares, F. M., Pires, L. F., Santos, L. O. B. d. S., Calhau, R. F., Moreira dos Santos Maculan, B. C., Coyle, K., Wang, S., Folmer, E., Pignatari Drucker, D., Campos, M. L. d. A., Marcondes, C. H., Almeida, M. B., Braghetto, K. R., Dias, G. A., Salim, J. A., Corrêa, F. E., de Abreu Moreira, D., Botazzo Delbem, A. C. & Saraiva, A. M.https://ceur-ws.org/Vol-3849/forum4.pdf

Research profiles

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

Address

University of Twente

Zilverling (building no. 11), room 2005
Hallenweg 19
7522 NH Enschede
Netherlands

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