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Luiz Olavo Bonino da Silva Santos is an Associate Professor at the University of Twente and at the Leiden University Medical Center (LUMC). His main research insterest are semantic data modeling, knowledge representation, and FAIR (Findable, Accessible, Interoperable, Reusable) data stewardship. His work focuses on enabling interoperability and machine-actionable data through the application of foundational ontologies, Semantic Web technologies and the FAIR principles.
He has been actively involved in the design and development of frameworks and infrastructures to support the realization of the FAIR principles, including approaches based on semantic modeling, FAIR Digital Objects, and distributed data architectures, supporting more transparent, reusable, and scalable data ecosystems.
He has contributed to several international research initiatives on data stewardship, FAIRification processes, and semantic technologies, bridging theory and practice in domains such as finances, security, law enforcement, healthcare and life sciences.
Expertise Computer Science Ontology Metadata Digital Object Conceptual Model FAIRification Data Management Digital Resource Modelers Organisations Together with my position at the University of Twente, I am also Associate Professor in the BioSemantics Group at the Leiden University Medica Center, in Leiden, the Netherlands.
Since 2014 I have been closely involved in the FAIR principles (findable, accessible, interoperable and reusable) movement. More specifically, I have participated in the research, design and development of a number of approaches and technologies to enable and/or facilitate the realisation of the FAIR principles such as FAIR metrics, FAIR Data Point, FAIRifier, FAIR Data Train and FAIR Digital Objects Framework.
Publications Jump to: 2026 | 2025
KGAP: An RDF knowledge graph of agricultural commodity prices (2026) Data in brief, 65 . Article 112607. Soares, F. M., Ferreira Pires, L., Corrêa, F. E., Bonino da Silva Santos, L. O. , Braghetto, K. R., de Abreu Moreira, D., Drucker, D. P., Botazzo Delbem, A. C. & Saraiva, A. M.https://doi.org/10.1016/j.dib.2026.112607 Mapping the Pain: How Modelers Experience and Respond to Common Domain Modeling Frustrations (2026) In Enterprise Design, Operations, and Computing: 29th International Conference, EDOC 2025, Lisbon, Portugal, September 9–12, 2025, Revised Selected Papers (pp. 193-209) (Lecture Notes in Computer Science; Vol. 16213). Springer. Valle, I., Sales, T. P., Guerra, E., Daneva, M., da Silva Santos, L. O. B. , Proper, H. & Guizzardi, G. https://doi.org/10.1007/978-3-032-15140-7_11 ChatGPT as a Semantic Engineering Assistant: Lessons from Ontology Design in the Agricultural Biodiversity Domain (2025) Biodiversity Information Science and Standards, 9 . Article e181272. Miranda Soares, F., Ferreira Pires, L., Bonino da Silva Santos, L. O. , Pignatari Drucker, D., de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Botazzo Delbem, A. C. & Saraiva, A. M.https://doi.org/10.3897/biss.9.181272 Business model innovation in a research ecosystem: the case of rare diseases (2025) International Journal of Organizational Analysis, 33 (11), 4385-4418. Sánchez, M. d. C., Sarmiento-Suárez, R., Hooft, R. W. W., Moreau, C., Bietrix, F., Jervelund, C., Mejer, M., Kreiner, K., Haddad, T., Bonino da Silva Santos, L. O. , Mimouni, Y., Rath, A., Posada de la Paz, M., Bermejo-Sánchez, E. & Julkowska, D.https://doi.org/10.1108/IJOA-06-2024-4588 Taxonomy OWLizer: A Tool for Converting Taxonomic Data into OWL (2025) Biodiversity Information Science and Standards, 9 . Soares, F., Saraiva, A., Ferreira Pires, L., Santos, L. & Drucker, D.https://doi.org/10.3897/biss.9.176413 A Semantic Interoperability Framework for Data-Centric Applications in Agriculture (2025) [Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Miranda Soares, F. https://doi.org/10.3990/1.9789036567626 A Novel UX-Based Approach for Ontology Evaluation: Applying Tree Testing to the Agricultural Product Types Ontology (2025) IEEE Access, 13 , 137986-138004. Article 11108173. Soares, F. M., Saraiva, A. M., Pires, L. F., Pignatari Drucker, D., Braghetto, K. R., Santos, L. O. B. d. S. , de Abreu Moreira, D., Corrêa, F. E. & Botazzo Delbem, A. C.https://doi.org/10.1109/ACCESS.2025.3595447 Unraveling the pain points of domain modeling (2025) Information and software technology, 183 . Article 107736. Valle, I., Sales, T. P., Guerra, E., Daneva, M., Guizzardi, R., Bonino da Silva Santos, L. O. , Proper, H. A. & Guizzardi, G.https://doi.org/10.1016/j.infsof.2025.107736 Restructuring Knowledge Graphs with Conceptual Models: Implications for Machine Learning Predictions in Drug Repurposing (2025) In Advanced Information Systems Engineering: 37th International Conference, CAiSE 2025, Vienna, Austria, June 16–20, 2025, Proceedings, Part II (pp. 297-313). Article Chapter 17 (Lecture Notes in Computer Science ; Vol. 15702). Springer. Bernabé, C., Zwart, R., Perdomo-Quinteiro, P., Jacobsen, A., Sales, T. P., Queralt-Rosinach, N., Wolstencroft, K., Santos, L. O. B. d. S. , Mons, B. & Roos, M. https://doi.org/10.1007/978-3-031-94571-7_17 The FAIR data point populator: collaborative FAIRification and population of FAIR data points (2025) BMC medical informatics and decision making, 25 (Suppl 1). Article 211. Wijnbergen, D., Kaliyaperumal, R., Burger, K., Bonino da Silva Santos, L. O. , Mons, B., Roos, M. & Mina, E.https://doi.org/10.1186/s12911-025-03022-7 Exploring a Large Language Model for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development (2025) Data Intelligence, 7 (2), 265-302. Soares, F. M., Saraiva, A. M., Pires, L. F., Santos, L. O. B. d. S. , de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C.https://doi.org/10.3724/2096-7004.di.2025.0020 Friend, Foe, or Target? Domain Models as Risk Deterrents, Risk Sources, and Assets at Risk (2025) In Research Challenges in Information Science: 19th International Conference, RCIS 2025, Seville, Spain, May 20–23, 2025, Proceedings, Part I (pp. 103-118) (Lecture Notes in Business Information Processing; Vol. 547 LNBIP). Springer. Valle, I., Sales, T. P., Guerra, E., Oliveira, Í., Guizzardi, R., Bonino da Silva Santos, L. O. , Proper, H. & Guizzardi, G. https://doi.org/10.1007/978-3-031-92474-3_7 GO-Plan: A goal-oriented method for FAIRification planning (2025) Information services & use, 45 (1-2), 100-124. Bernabé, C., Valle, I., Prince Sales, T., Schultes, E., van Ulzen, N., Silva Souza, V. E., Jacobsen, A., Bonino da Silva Santos, L. O. , Mons, B. & Roos, M.https://doi.org/10.1177/18758789251324008 Exploring a Large Language Model for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development (2025) [Working paper › Preprint]. ArXiv.org. Soares, F. M., Saraiva, A. M., Pires, L. F., Santos, L. O. B. d. S. , de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C. https://doi.org/10.48550/arXiv.2504.18651 Restructuring knowledge graphs with conceptual models - Supplementary material (2025) [Dataset Types › Dataset]. Zenodo. Bernabé, C., Zwart, R., Perdomo-Quinteiro, P., Jacobsen, A., Prince Sales, T., Queralt-Rosinach, N., Wolstencroft, K., Bonino da Silva Santos, L. O. , Mons, B. & Roos, M. https://doi.org/10.5281/zenodo.15163097 HTTP-Based Implementation Strategies for the FAIR Digital Object Framework Identifier Resolution (2025) Open Conference Proceedings, 5 . Santos, L. O. B. d. S. , Fonseca, C. M. & Sales, T. P.https://doi.org/10.52825/ocp.v5i.1423 FAIRDataTeam/FAIRDataPoint-client (2025) [Dataset Types › Dataset]. Zenodo. Slifka, J., Suchánek, M., Dennis & Bonino, L. O. https://doi.org/10.5281/zenodo.15020415 Supporting Data for "Exploring ChatGPT-4 for Transforming Taxonomic Data into OWL: Lessons Learned and Implications for Ontology Development" (2025) [Dataset Types › Dataset]. Zenodo. Soares, F., Saraiva, A. M., Ferreira Pires, L., Bonino, L. , de Abreu Moreira, D., Corrêa, F. E., Braghetto, K. R., Pignatari Drucker, D. & Botazzo Delbem, A. C. https://doi.org/10.5281/zenodo.12684940 JRC FAIR Data Guidelines (2025) [Book/Report › Report]. Publications Office of the European Union. Lowenthal, H., Bonino da Silva Santos, L. O. , Chiarelli, C., Cusinato, A., Ferigato, C., FRIIS-CHRISTENSEN, A., Kemper, T., Perrotta, D. & Wittwehr, C. https://doi.org/10.2760/5646214 GO-Plan: A goal-oriented method for FAIRification planning - supplementary material (2025) [Dataset Types › Dataset]. Zenodo. Bernabé, C., Valle Sousa, I., Prince Sales, T., Schultes, E., van Ulzen, N., Silva Souza, V. E., Jacobsen, A., Bonino da Silva Santos, L. O. , Barend, M. & Roos, M. https://doi.org/10.5281/zenodo.14780347 Research profiles 
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