• Medicine and Dentistry

    • Patient
    • Therapeutic Procedure
    • Inpatient
    • Disease Activity
    • Spontaneous Remission
  • Nursing and Health Professions

    • Rheumatoid Arthritis
    • Fatigue
  • Psychology

    • Health


Epidemiology, farmacology and healtheconomics in rheumatic diseases. 

Outcome research using ICT and IRT including computer adative tests.



2023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseasesAnnals of the rheumatic diseases, Article POS0307, 437-438 (E-pub ahead of print/First online). Dures, E., Farisoğulları, B., Santos, E. J. F., Molto, A., Feldthusen, C., Harris, C., Elling-Audersch, C., Connolly, D., Elefante, E., Estévez-López, F., Bini, I., Primdahl, J., Hoeper, K., Urban, M., van de Laar, M. A. F. J., Redondo, M., Böhm, P., Amarnani, R., Hayward, R., … Machado, P. M. value of gastrointestinal symptoms and patient risk factors for NSAID-associated gastrointestinal ulcers defined by endoscopy? Insights from a pooled analysis of two naproxen clinical trialsPLoS ONE, 18, Article e0284358, 1-14 (E-pub ahead of print/First online). van de Laar, M. A. F. J., Schöfl, R., Prevoo, M. & Jastorffi, J. Impact of Pain and Disease Activity on Improvements in Fatigue: Results From 2 Baricitinib Phase 3 Clinical TrialsJournal of Clinical Rheumatology, 29(3), 139-144. Fautrel, B., Wu, J., Wang, D., Haladyj, E., Van De Laar, M. A. F. J. & Takeuchi, T.
Healthcare professionals’ perceptions on barriers and facilitators to DMARD use in rheumatoid arthritisBMC health services research, 22(1), Article 62. Voshaar, M. J. H., van den Bemt, B. J. F., van de Laar, M. A. F. J., van Dulmen, A. M. & Vriezekolk, J. E. variability of rheumatoid arthritis: Balancing between population and individual. University of Twente. Versteeg, G. A. involvement in rheumatoid arthritis care to improve disease activity-based management in daily practice: A randomized controlled trialPatient education and counseling, 105(5), 1244-1253. Spijk-de Jonge, M. J., Weijers, J. M., Teerenstra, S., Elwyn, G., van de Laar, M. A. F. J., van Riel, P. L. C. M., Huis, A. M. P. & Hulscher, M. E. J. L. radiological progression remains associated with long-term joint damage in real-world rheumatoid arthritis patients treated to the target of remissionScandinavian journal of rheumatology, 51(2), 87-96. Versteeg, G. A., Steunebrink, L. M. M., Vonkeman, H. E., ten Klooster, P. M., van der Bijl, A. E. & van de Laar, M. A. F. J. cost-effectiveness analyses comparing combinations of urate lowering therapy and anti-inflammatory treatment in gout patientsPLoS ONE, 17(1 January), Article e0261940. van de Laar, C. J., Janssen, C. A., Janssen, M., Oude Voshaar, M. A. H., Maiwenn, J. A. & van de Laar, M. A. F. J. is associated with disease activity in some, but not all, patients living with rheumatoid arthritis: disentangling “between-person” and “within-person” associationsBMC Rheumatology, 6(1), Article 3. Versteeg, G. A., ten Klooster, P. M. & van de Laar, M. A. F. J.

Other contributions

1:  Cost-Effectiveness of a JAK1/JAK2 Inhibitor vs a Biologic Disease-Modifying Antirheumatic Drug (bDMARD) in a Treat-to-Target Strategy for Rheumatoid Arthritis
Celine J Van De Laar, Martijn A H Oude Voshaar, Walid K H Fakhouri, Liliana Zaremba-Pechmann, Francesco De Leonardis, Inmaculada De La Torre, Mart A F J Van De Laar
Clinicoecon Outcomes Res. 2020; 12: 213–222.  Published online 2020 Apr 15. doi: 10.2147/CEOR.S231558
PMCID: PMC7167259

2:  International Consortium for Health Outcome Measurement Set of Outcomes That Matter to People Living With Inflammatory Arthritis: Consensus From an International Working Group
Martijn A. H. Oude Voshaar, Zofia Das Gupta, Johannes W. J. Bijlsma, Annelies Boonen, Jeffrey Chau, Delphine S. Courvoisier, Jeffrey R. Curtis, Benjamin Ellis, Sofia Ernestam, Laure Gossec, Christine Hale, Jennifer Hornjeff, Katy Y. Y. Leung, Merav Lidar, Phillip Mease, Kaleb Michaud, Girish M. Mody, Mwidimi Ndosi, Christina H. Opava, Geraldo R. C. Pinheiro, Matthew Salt, Enrique R. Soriano, William J. Taylor, Maria J. H. Voshaar, Angelique E. A. M. Weel, Maarten de Wit, Nico Wulffraat, Mart A. F. J. van de Laar, Harald E. Vonkeman
Arthritis Care Res (Hoboken) 2019 Dec; 71(12): 1556–1565.  Published online 2019 Nov 29. doi: 10.1002/acr.23799
PMCID: PMC6900179

3:  Psychometric properties and cross-language equivalence of the revised Bristol Rheumatoid Arthritis Fatigue and the Rheumatoid Arthritis Impact of Disease scales in rheumatoid arthritis
Martijn A. H. Oude Voshaar, Christina Bode, Sarah Hewlett, John Kirwan, Laure Gossec, Mart A. F. J. van de Laar
Qual Life Res. 2019; 28(9): 2543–2552.  Published online 2019 Apr 26. doi: 10.1007/s11136-019-02188-8
PMCID: PMC6698264

4:  A systematic literature review of patient-reported outcome measures used in gout: an evaluation of their content and measurement properties
Carly A. Janssen, Martijn A. H. Oude Voshaar, Peter M. ten Klooster, Tim L. Th. A. Jansen, Harald E. Vonkeman, Mart A. F. J. van de Laar
Health Qual Life Outcomes. 2019; 17: 63.  Published online 2019 Apr 11. doi: 10.1186/s12955-019-1125-x
PMCID: PMC6460780

5:  Development and preliminary evaluation of a short self-report measure of generalized pain hypersensitivity
Peter F van Bemmel, Martijn AH Oude Voshaar, Peter M ten Klooster, Harald E Vonkeman, Mart AFJ van de Laar
J Pain Res. 2019; 12: 395–404.  Published online 2019 Jan 17. doi: 10.2147/JPR.S182287
PMCID: PMC6342225

6:  Towards standardized patient reported physical function outcome reporting: linking ten commonly used questionnaires to a common metric
M. A. H. Oude Voshaar, H. E. Vonkeman, D. Courvoisier, A. Finckh, L. Gossec, Y. Y. Leung, K. Michaud, G. Pinheiro, E. Soriano, N. Wulfraat, A. Zink, M. A. F. J. van de Laar
Qual Life Res. 2019; 28(1): 187–197.  Published online 2018 Oct 13. doi: 10.1007/s11136-018-2007-0
PMCID: PMC6339672

7:  A retrospective analysis of medication prescription records for determining the levels of compliance and persistence to urate-lowering therapy for the treatment of gout and hyperuricemia in The Netherlands
C. A. Janssen, M. A. H. Oude Voshaar, H. E. Vonkeman, M. Krol, M. A. F. J. van de Laar
Clin Rheumatol. 2018; 37(8): 2291–2296.  Published online 2018 May 2. doi: 10.1007/s10067-018-4127-x
PMCID: PMC6061072

8:  Quality of care in gout: a clinical audit on treating to the target with urate lowering therapy in real-world gout patients
Carly A. Janssen, Tim L. Th. A. Jansen, Martijn A. H. Oude Voshaar, Harald E. Vonkeman, Mart A. F. J. van de Laar
Rheumatol Int. 2017; 37(9): 1435–1440.  Published online 2017 Jul 26. doi: 10.1007/s00296-017-3777-3
PMCID: PMC5570767

9:  Measuring everyday functional competence using the Rasch assessment of everyday activity limitations (REAL) item bank
Martijn A. H. Oude Voshaar, Peter M. ten Klooster, Harald E. Vonkeman, Mart A. F. J. van de Laar
Qual Life Res. 2017; 26(11): 2949–2959.  Published online 2017 Jun 21. doi: 10.1007/s11136-017-1627-0
PMCID: PMC5655561

10:  Initial combination therapy versus step-up therapy in treatment to the target of remission in daily clinical practice in early rheumatoid arthritis patients: results from the DREAM registry
L. M. M. Steunebrink, G. A. Versteeg, H. E. Vonkeman, P. M. ten Klooster, H. H. Kuper, T. R. Zijlstra, P. L. C. M. van Riel, M. A. F. J. van de Laar
Arthritis Res Ther. 2016; 18: 60.  Published online 2016 Mar 8. doi: 10.1186/s13075-016-0962-9
PMCID: PMC4784382

Research profiles


University of Twente

Cubicus (building no. 41), room B125
De Zul 10
7522 NJ Enschede

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