Technohal

dr. M.C. van Maaren (Marissa)

Assistant Professor
BMS-TPS-HTSR
Technohal 3304
m.c.vanmaaren@utwente.nl
+31534898007
Business card

I am a clinical epidemiologist and assistant professor of oncology care at the University of Twente. I also have an external positition at the Netherlands Comprehensive Cancer Organisation (IKNL). I obtained my PhD in 2018 at the University of Twente. My thesis was entitled: ā€œLocal management of early breast cancer and clinical risk prediction of survivalā€. In this thesis I mainly focused on 1) the evaluation of breast-conserving therapy and mastectomy in the daily breast cancer population, in which I worked with several methodologies suitable for observational research, and 2) development and validation of prediction models for use in daily clinical practice.

My current research activities include research on long-term outcomes following a variety of treatments for breast cancer. I am involved in the registration of pathologically confirmed recurrences in the Netherlands Cancer Registry (NCR), which is hosted by IKNL. I am part of the NABOR project team working on a by ZonMW subsidised research on personalised breast cancer follow-up. Here I am responsible for the development/update of the INFLUENCE 3.0 prediction tool that estimates the risk of locoregional recurrence and second primary breast cancer, for which I use the data from IKNL.

I teach on research methodology and quality of care in several modules within theĀ BMT/BME and GZW/HS bachelor and master programmes.Ā Besides, I am co-developer of a new learning line in the BMT bachelor on methodology and statistics.

Furthermore, I am a board member of the Netherlands Epidemiology Society (VvE) in which I focus on advanced epidemiological methods: how do we make sure epidemiologists within and outside of academia know of these methodologies and how can we spread our knowledge. In addition, I am member and coordinator of the national breast cancer working groups (NABON-BOOG) scientific evaluation committee of NCR data requests.

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Therapeutic Procedure
    • Mastectomy
    • Recurrent Disease
    • Breast
    • Cancer Registry
    • Overall Survival

Organisations

Publications

2025

Implementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020ā€“2023, using registry data and questionnaires (2025)Radiation Oncology, 20(1). Article 99. Eijkelboom, A. H., van Beek, E. J. A., Stam, M. R., Westhoff, P., van Maaren, M. C., Sattler, M. G. A., Bantema-Joppe, E. J., Verheij, M., van den Bongard, D. H. J. G. & Siesling, S.https://doi.org/10.1186/s13014-025-02669-wTrends in Surgical Treatment for cT4 Breast Cancer After Neoadjuvant Systemic Therapy: A Nationwide Study in The Netherlands (2025)Annals of surgical oncology, 32(12), 8668-8677. Jansen, B. A. M., Kelder, J. C., Borchert, T., van Uden, D. J. P., van der Leij, F., Schröder, C., Doeksen, A., Siesling, S., van Maaren, M. C. & Postma, E. L.https://doi.org/10.1245/s10434-025-17585-2Trends in use of magnetic resonance imaging and partial breast irradiation between 2011ā€“2022 in the Netherlands: A population-based study (2025)Clinical and Translational Radiation Oncology, 55. Article 101039. Civil, Y. A., Eijkelboom, A. H., Veldink, A. E., van Maarenc, M. C., Maduro, J. H., Duvivier, K. M., Siesling, S. & van den Bongard, H. J. G. D.https://doi.org/10.1016/j.ctro.2025.101039Doubly Robust Estimation of Marginal Cumulative Incidence Curves for Competing Risk Analysis (2025)Statistics in medicine, 44(18-19). Article e70066. van Hage, P., le Cessie, S., van Maaren, M. C., Putter, H. & van Geloven, N.https://doi.org/10.1002/sim.70066Different needs ask for different care: Breast cancer patientsā€™ preferences regarding assessment of care needs and information provision in personalized aftercare (2025)European journal of oncology nursing, 76. Article 102873. Dekker-Klaassen, A., Drossaert, C. H. C., Folkert, L. S., van der Lee, M. L., Guerrero-Paez, C., Claassen, S., Korevaar, J. C., Siesling, S., Maaren, M. v., Retel, V., Leeuwen, E. v., Knottnerus, B., Burgers, J., Vrancken, M. J., Siemerink, E., Honkoop, A., Veltman, J., Zeillemaker, A., Mann, R., ā€¦ Hezewijk, M. v.https://doi.org/10.1016/j.ejon.2025.102873Five-year conditional relative survival up to 10 years post-diagnosis among adolescent and young adult breast cancer patients by age, stage, and receptor subtype (2025)Journal of the National Cancer Center, 5(3), 297-305. Vrancken Peeters, N. J. M. C., van der Meer, D. J., Kok, M., van Maaren, M. C., Baas-Vrancken Peeters, M.-J. T. F. D., Siesling, S., van der Graaf, W. T. A. & Husson, O.https://doi.org/10.1016/j.jncc.2025.01.005Notification of locoregional breast cancer recurrence based on pathology reports: A nationwide validation study with the Netherlands Cancer Registry (2025)Cancer epidemiology, 96. Article 102780. van Maaren, M. C., Voorham, Q. J. M., Wijnen, E. M., de Munck, L., Wesseling, J., Visser, O. & Siesling, S.https://doi.org/10.1016/j.canep.2025.102780Deintensification of Radiotherapy Use in Treatment of Ductal Carcinoma In Situ in the Netherlandsā€“A Nationwide Overview From 2008 Until 2022 (2025)Clinical oncology, 38. Article 103740. Evers, J., van der Sangen, M. J. C., van Maaren, M. C., Maduro, J. H., Strobbe, L., Aarts, M. J., Bloemers, M. C. W. M., Wesseling, J., van den Bongard, D. H. J. G., Struikmans, H. & Siesling, S.https://doi.org/10.1016/j.clon.2024.103740The INFLUENCE 3.0 model: updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy (2025)The Breast, 79. Article 103829. van Maaren , M. C., Hueting, T. A., van Uden, D. J. P., van Hezewijk, M., de Munck, L., Mureau, M. A. M., Seegers, P. A., Voorham, Q. J. M., Schmidt, M. K., Sonke, G. S., Groothuis-Oudshoorn, C. G. M. & Siesling, S.https://doi.org/10.1016/j.breast.2024.10382970-Gene signature-guided adjuvant systemic treatment adjustments in early-stage ER+ā€‰breast cancer patients: 7-year follow-up of a prospective multicenter cohort study (2025)Breast cancer research and treatment, 209, 331–340. Verreck, E. E. F., Kuijer, A., van Steenhoven, J. E. C., Volders, J. H., van der Velden, A. W. G., Siesling, S., Timmer-Bonte, A. N. H., Smilde, T. J., Imholz, A. L. T., Blanken-Peeters, C. F. J. M., de Valk, B., Vrijaldenhoven, S., Lastdrager, W. B., Haringhuizen, A. W., Hunting, J. C. B., Hovenga, S., Nieboer, P., Zuetenhorst, H. M., Tetteroo, G. W. M., ā€¦ van Dalen, T.https://doi.org/10.1007/s10549-024-07496-3

Research profiles

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

Address

University of Twente

Technohal (building no. 18), room 3304
Hallenweg 5
7522 NH Enschede
Netherlands

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