Expertise
Medicine & Life Sciences
# Electrodes
# In Vitro Techniques
# Induced Pluripotent Stem Cells
# Kleefstra Syndrome
# Neurons
Engineering & Materials Science
# Electrodes
# Neurons
# Stem Cells
Organisations
Publications
Recent
van Rhijn, J. R., Shi, Y., Bormann, M., Mossink, B.
, Frega, M., Recaioglu, H., Hakobjan, M., Klein Gunnewiek, T., Schoenmaker, C., Palmer, E., Faivre, L., Kittel-Schneider, S., Schubert, D., Brunner, H., Franke, B., & Nadif Kasri, N. (2022).
Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons.
Neurobiology of disease,
163, [105587].
https://doi.org/10.1016/j.nbd.2021.105587
Linda, K., Lewerissa, E. I., Verboven, A. H. A., Gabriele, M.
, Frega, M., Klein Gunnewiek, T. M., Devilee, L., Ulferts, E., Hommersom, M., Oudakker, A., Schoenmaker, C., van Bokhoven, H., Schubert, D., Testa, G., Koolen, D. A., de Vries, B. B. A., & Nadif Kasri, N. (2022).
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders.
Autophagy,
18(2), 423-442.
https://doi.org/10.1080/15548627.2021.1936777
Mossink, B., van Rhijn, J. R., Wang, S., Linda, K., Vitale, M. R., Zöller, J. E. M., van Hugte, E. J. H., Bak, J., Verboven, A. H. A., Selten, M., Negwer, M., Latour, B. L., van der Werf, I., Keller, J. M., Klein Gunnewiek, T. M., Schoenmaker, C., Oudakker, A., Anania, A., Jansen, S., ... Nadif Kasri, N. (2022).
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks.
Molecular Psychiatry,
27, 1-18.
https://doi.org/10.1038/s41380-021-01117-x
Muzzi, L., Di Lisa, D., Arnaldi, P., Aprile, D., Pastorino, L., Martinoia, S.
, & Frega, M. (2021).
Rapid generation of functional engineered 3D human neuronal assemblies: Network dynamics evaluated by micro-electrodes arrays.
Journal of neural engineering,
18(6), [066030].
https://doi.org/10.1088/1741-2552/ac3e02
Mossink, B., Verboven, A. H. A., van Hugte, E. J. H., Klein Gunnewiek, T. M., Parodi, G., Linda, K., Schoenmaker, C., Kleefstra, T., Kozicz, T., van Bokhoven, H., Schubert, D., Nadif Kasri, N.
, & Frega, M. (2021).
Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro.
Stem cell reports,
16(9), 2182-2196.
https://doi.org/10.1016/j.stemcr.2021.07.001
Muzzi, L., Falappa, M., Maccione, A., di Lisa, D.
, Frega, M., & Martinoia, S. (2021).
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array. In
2021 10th International IEEE/EMBS Conference on Neural Engineering, NER 2021 (pp. 123-127). [9441261] (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2021). IEEE Computer Society Press.
https://doi.org/10.1109/NER49283.2021.9441261
Pires Monteiro, S.
, Voogd, E.
, Muzzi, L., De Vecchis, G., Mossink, B.
, Levers, M.
, Hassink, G.
, van Putten, M.
, Le Feber, J.
, Hofmeijer, J.
, & Frega, M. (2021).
Neuroprotective effect of hypoxic preconditioning and neuronal activation in a in vitro human model of the ischemic penumbra.
Journal of neural engineering,
18(3), [036016].
https://doi.org/10.1088/1741-2552/abe68a
Klein Gunnewiek, T. M., Van Hugte, E. J. H.
, Frega, M., Guardia, G. S., Foreman, K., Panneman, D., Mossink, B., Linda, K., Keller, J. M., Schubert, D., Cassiman, D., Rodenburg, R., Vidal Folch, N., Oglesbee, D., Perales-Clemente, E., Nelson, T. J., Morava, E., Nadif Kasri, N., & Kozicz, T. (2020).
m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity.
Cell reports,
31(3), [107538].
https://doi.org/10.1016/j.celrep.2020.107538
Frega, M., Selten, M., Mossink, B., Keller, J. M., Linda, K., Moerschen, R., Qu, J., Koerner, P., Jansen, S., Oudakker, A., Kleefstra, T., van Bokhoven, H., Zhou, H., Schubert, D., & Nadif Kasri, N. (2020).
Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype.
Cell reports,
30(1), 173-186.e6.
https://doi.org/10.1016/j.celrep.2019.12.002
Muzzi, L.
, Hassink, G.
, Levers, M. R., Jansman, M. M. T.
, Frega, M.
, Hofmeijer, J.
, van Putten, M. J. A. M.
, & le Feber, J. (2019).
Mild stimulation improves neuronal survival in an in-vitro model of the ischemic penumbra.
Journal of neural engineering,
17(1), [016001].
https://doi.org/10.1088/1741-2552/ab51d4
UT Research Information System
Courses Academic Year 2021/2022
Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses Academic Year 2020/2021
Contact Details
Visiting Address
University of Twente
Faculty of Science and Technology
Technohal
(building no. 18), room 3383
Hallenweg 5
7522NH Enschede
The Netherlands
Mailing Address
University of Twente
Faculty of Science and Technology
Technohal
3383
P.O. Box 217
7500 AE Enschede
The Netherlands