Technohal

M. Frega PhD (Monica)

Assistant Professor
TNW-BIS-CNPH
Technohal 3383
m.frega@utwente.nl
+31534891802
Business card

Expertise

  • Neuroscience

    • In Vitro
    • Neuron
    • Brain
    • In Vivo

  • Biochemistry, Genetics and Molecular Biology

    • Microelectrode
    • Induced Pluripotent Stem Cell
    • Accuracy

  • Medicine and Dentistry

    • Cells

Organisations

Publications

2024

Modeling mTORopathy-related epilepsy in cultured murine hippocampal neurons using the multi-electrode array (2024)Experimental neurology, 379. Article 114874. Heuvelmans, A. M., Proietti Onori, M., Frega, M., de Hoogen, J. D., Nel, E., Elgersma, Y. & van Woerden, G. M.https://doi.org/10.1016/j.expneurol.2024.114874Neuroprotective role of lactate in a human in vitro model of the ischemic penumbra (2024)Scientific reports, 14(1). Article 7973 (E-pub ahead of print/First online). Cerina, M., Levers, M., Keller, J. M. & Frega, M.https://doi.org/10.1038/s41598-024-58669-5

2023

Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells (2023)Journal of neural engineering, 20(6), 1741-2552. Article 066038. Voogd, E. J. H. F., Doorn, N., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1088/1741-2552/ad17f3SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes (2023)Brain, 146(12), 5153-5167. Van Hugte, E. J. H., Lewerissa, E. I., Wu, K. M., Scheefhals, N., Parodi, G., Van Voorst, T. W., Puvogel, S., Kogo, N., Keller, J. M., Frega, M., Schubert, D., Schelhaas, H. J., Verhoeven, J., Majoie, M., Van Bokhoven, H. & Nadif Kasri, N.https://doi.org/10.1093/brain/awad245A human in vitro neuronal model for studying homeostatic plasticity at the network level (2023)Stem cell reports, 18(11), 2222-2239. Yuan, X., Puvogel, S., van Rhijn, J. R., Ciptasari, U., Esteve-Codina, A., Meijer, M., Rouschop, S., van Hugte, E. J. H., Oudakker, A., Schoenmaker, C., Frega, M., Schubert, D., Franke, B. & Nadif Kasri, N.https://doi.org/10.1016/j.stemcr.2023.09.011Neuronal Responses to Ischemia: Scoping Review of Insights from Human-Derived In Vitro Models (2023)Cellular and molecular neurobiology, 43(7), 3137-3160. Voogd, E. J. H. F., Frega, M. & Hofmeijer, J.https://doi.org/10.1007/s10571-023-01368-yAn in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome (2023)Stem cell reports, 18(8), 1686-1700. Doorn, N., Hugte, E. J. H. v., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Nadif Kasri, N. & Putten, M. J. A. M. v.https://doi.org/10.1016/j.stemcr.2023.06.003The potential of in vitro neuronal networks cultured on micro electrode arrays for biomedical research (2023)Progress in Biomedical Engineering, 5(3). Article 032002. Cerina, M., Piastra, M. C. & Frega, M.https://doi.org/10.1088/2516-1091/acce12Human-Derived Cortical Neurospheroids Coupled to Passive, High-Density and 3D MEAs: A Valid Platform for Functional Tests (2023)Bioengineering, 10(4). Article 449. Muzzi, L., Di Lisa, D., Falappa, M., Pepe, S., Maccione, A., Pastorino, L., Martinoia, S. & Frega, M.https://doi.org/10.3390/bioengineering10040449A micropatterned thermoplasmonic substrate for neuromodulation of in vitro neuronal networks (2023)Acta biomaterialia, 158, 281-291. Andolfi, A., Arnaldi, P., Donatella Di, L., Pepe, S., Frega, M., Fassio, A., Lagazzo, A., Martinoia, S. & Pastorino, L.https://doi.org/10.1016/j.actbio.2022.12.036

Research profiles

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2023/2024

Address

University of Twente

Technohal (building no. 18), room 3383
Hallenweg 5
7522 NH Enschede
Netherlands

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