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drs. M.J. Oude Wolcherink (Martijn)

PhD Candidate

About Me

During my studies in technical medicine and health sciences, I discovered I would like to commit myself to improving our healthcare system. I believe the saying "prevention is better than cure" is very relevant for healthcare, especially within the field of cardiovascular disease. This is also the main theme of my PhD track, as I am involved in three studies that focus on early detection or screening of cardiovascular disease. Within these studies, I work on the health economic evaluation of the clinical trial and developing a simulation model to extrapolate follow up results to lifetime outcomes. Below each study is shortly summarised.

CONCRETE focusses on availability of CT-based calcium scoring in the first-line care to adequately diagnose coronary artery disease in individuals with aspecific angina pectoris or atypical chest discomfort.

EARLY SYNERGY is the second stage in a 2-stage screeningsprogram. In the first stage screening with a CT-based calcium score in asymptomatic individuals is performed. In EARLY SYNERGY, the impact of detection of ischaemia by subsequent stress MRI as indicator for preventive invasive treatment in individuals with high CT-calcium score is studied.

In RED-CVD, a screening strategy for cardiovascular disease is developed for COPD and diabetes patients. A newly developed questionnaire will indicate which patients require further cardiovascular diagnostics.

Expertise

Medicine & Life Sciences
Asthma
Calcium
Chest Pain
Coronary Artery Disease
General Practitioners
Inhalation
Myocardial Perfusion Imaging
Respiratory Therapy

Publications

Recent
Koopman, M. Y., Reijnders, J. J. W., Willemsen, R. T. A., Van Bruggen, R. , Doggen, C. J. M., Kietselaer, B. , Oude Wolcherink, M. J., Van Ooijen, P. M. A., Gratama, J. W. C., Braam, R., Oudkerk, M., Van Der Harst, P., Dinant, G. J., & Vliegenthart, R. (2022). Coronary calcium scoring as first-line test to detect and exclude coronary artery disease in patients presenting to the general practitioner with stable chest pain: protocol of the cluster-randomised CONCRETE trial. BMJ open, 12(4), [e055123]. https://doi.org/10.1136/bmjopen-2021-055123
Ties, D., van Dorp, P., Pundziute, G., van der Aalst, C. M., Gratama, J. W. C., Braam, R. L., Kuijpers, D., Lubbers, D. D., van der Bilt, I. A. C., Westenbrink, B. D. , Wolcherink, M. J. O. , Doggen, C. J. M., IĆĄgum, I., Nijveldt, R., de Koning, H. J., Vliegenthart, R., Oudkerk, M., & van der Harst, P. (2022). Early detection of obstructive coronary artery disease in the asymptomatic high-risk population: objectives and study design of the EARLY-SYNERGY trial. American heart journal, 246, 166-177. https://doi.org/10.1016/j.ahj.2022.01.005

Contact Details

Visiting Address

University of Twente
Faculty of Behavioural, Management and Social Sciences
Technohal (building no. 18), room 3106
Hallenweg 5
7522NH  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Behavioural, Management and Social Sciences
Technohal  3106
P.O. Box 217
7500 AE Enschede
The Netherlands