prof.dr. M.M.A.E. Claessens (Mireille) | University of Twente

Alpha-Synuclein

Alpha-Synuclein

Membranes

Membranes

Proteins

Parkinson Disease

Lipids

Amyloid

Faculty of Science and Technology (TNW), Nanobiophysics (NBP)

Semerdzhiev, S. A., Lindhoud, S., Stefanovic, A., Subramaniam, V., Van Der Schoot, P., & Claessens, M. M. A. E. (2018). Hydrophobic-Interaction-Induced Stiffening of α -Synuclein Fibril Networks. Physical review letters, 120(20), [208102]. DOI: 10.1103/PhysRevLett.120.208102

Hassink, G. C., Raiss, C. C., Segers-Nolten, I. M. J., Van Wezel, R. J. A., Subramaniam, V., Le Feber, J., & Claessens, M. M. A. E. (2018). Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons. PLoS ONE, 13(3), [e0193763]. DOI: 10.1371/journal.pone.0193763

Fakhree, M. A. A., Nolten, I. S., Blum, C., & Claessens, M. M. A. E. (2018). Different Conformational Subensembles of the Intrinsically Disordered Protein α-Synuclein in Cells. Journal of physical chemistry letters, 9(6), 1249-1253. DOI: 10.1021/acs.jpclett.8b00092

Iyer, A., Roeters, S. J., Kogan, V., Woutersen, S., Claessens, M. M. A. E., & Subramaniam, V. (2017). C-Terminal Truncated α-Synuclein Fibrils Contain Strongly Twisted β-Sheets. Journal of the American Chemical Society, 139(43), 15392-15400. DOI: 10.1021/jacs.7b07403

Chaudhary, H., Subramaniam, V., & Claessens, M. M. A. E. (2017). Direct Visualization of Model Membrane Remodeling by α-Synuclein Fibrillization. ChemPhysChem, 18(12), 1620-1626. DOI: 10.1002/cphc.201700050

Semerdzhiev, S. A., Shvadchak, V. V., Subramaniam, V., & Claessens, M. M. A. E. (2017). Non-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates. Scientific reports, 7(1), [7699]. DOI: 10.1038/s41598-017-06532-1

Arends, F., Chaudhary, H., Janmey, P., Claessens, M. M. A. E., & Lieleg, O. (2017). Lipid Head Group Charge and Fatty Acid Configuration Dictate Liposome Mobility in Neurofilament Networks. Macromolecular bioscience, 17(2), [1600229]. DOI: 10.1002/mabi.201600229

Sidhu, A., Segers-Nolten, G. M. J., Raussens, V., Claessens, M. M. A. E., & Subramaniam, V. (2017). Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation. ACS chemical neuroscience, 8(3), 538-547. DOI: 10.1021/acschemneuro.6b00287

Iyer, A., Schilderink, N., Claessens, M. M. A. E., & Subramaniam, V. (2016). Membrane-Bound Alpha Synuclein Clusters Induce Impaired Lipid Diffusion and Increased Lipid Packing. Biophysical journal, 111(11), 2440-2449. DOI: 10.1016/j.bpj.2016.10.016

Abolghassemi Fakhree, M. A., Blum, C., & Claessens, M. M. A. E. (2016). The number of α-synuclein proteins per vesicle gives insights into its physiological function.

+31534893157 (if no answer)

m.m.a.e.claessens@utwente.nl

Visiting Address

University of Twente
Faculty of Science and Technology
Horst Complex (building no. 20), room ZH163
De Horst 2
7522LW Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst Complex ZH163
P.O. Box 217
7500 AE Enschede
The Netherlands

Faculty of Science and Technology (TNW), Nanobiophysics (NBP)

University of Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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