prof.dr. M.M.A.E. Claessens (Mireille) | University of Twente

Alpha-Synuclein

Membranes

Lipids

Proteins

Proteins

Membranes

Amyloid

Parkinson Disease

Faculty of Science and Technology (TNW), Nanobiophysics (NBP)

Hassink, G. C., Raiss, C. C., Segers-Nolten, I. M. J., Van Wezel, R. J. A., Subramaniam, V., Le Feber, J., & Claessens, M. M. A. E. (2018). Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons. PLoS ONE, 13(3), [e0193763]. DOI: 10.1371/journal.pone.0193763

Fakhree, M. A. A., Nolten, I. S., Blum, C., & Claessens, M. M. A. E. (2018). Different Conformational Subensembles of the Intrinsically Disordered Protein α-Synuclein in Cells. Journal of physical chemistry letters, 9(6), 1249-1253. DOI: 10.1021/acs.jpclett.8b00092

Semerdzhiev, S. A., Shvadchak, V. V., Subramaniam, V., & Claessens, M. M. A. E. (2017). Non-uniform self-assembly: On the anisotropic architecture of α-synuclein supra-fibrillar aggregates. Scientific reports, 7(1), [7699]. DOI: 10.1038/s41598-017-06532-1

Sidhu, A., Segers-Nolten, G. M. J., Raussens, V., Claessens, M. M. A. E., & Subramaniam, V. (2017). Distinct Mechanisms Determine α-Synuclein Fibril Morphology during Growth and Maturation. ACS chemical neuroscience, 8(3), 538-547. DOI: 10.1021/acschemneuro.6b00287

Arends, F., Chaudhary, H., Janmey, P., Claessens, M. M. A. E., & Lieleg, O. (2017). Lipid Head Group Charge and Fatty Acid Configuration Dictate Liposome Mobility in Neurofilament Networks. Macromolecular bioscience, 17(2), [1600229]. DOI: 10.1002/mabi.201600229

Chaudhary, H., Subramaniam, V., & Claessens, M. M. A. E. (2017). Direct Visualization of Model Membrane Remodeling by α-Synuclein Fibrillization. ChemPhysChem, 18(12), 1620-1626. DOI: 10.1002/cphc.201700050

Iyer, A., Roeters, S. J., Kogan, V., Woutersen, S., Claessens, M. M. A. E., & Subramaniam, V. (2017). C-Terminal Truncated α-Synuclein Fibrils Contain Strongly Twisted β-Sheets. Journal of the American Chemical Society, 139(43), 15392-15400. DOI: 10.1021/jacs.7b07403

Abolghassemi Fakhree, M. A., Blum, C., & Claessens, M. M. A. E. (2016). The number of α-synuclein proteins per vesicle gives insights into its physiological function.

Chaudhary, H., Iyer, A. S., Subramaniam, V., & Claessens, M. M. A. E. (2016). α-Synuclein Oligomers Stabilize Pre-Existing Defects in Supported Bilayers and Propagate Membrane Damage in a Fractal-Like Pattern. Langmuir, 32(45), 11827-11836. DOI: 10.1021/acs.langmuir.6b02572

Iyer, A., Schilderink, N., Claessens, M. M. A. E., & Subramaniam, V. (2016). Membrane-Bound Alpha Synuclein Clusters Induce Impaired Lipid Diffusion and Increased Lipid Packing. Biophysical journal, 111(11), 2440-2449. DOI: 10.1016/j.bpj.2016.10.016

+31534893157 (if no answer)

m.m.a.e.claessens@utwente.nl

Visiting Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst (building no. 28), room 163
De Horst 2
7522LW Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst 163
P.O. Box 217
7500 AE Enschede
The Netherlands

Faculty of Science and Technology (TNW), Nanobiophysics (NBP)

University of Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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