M.R. Levers BSc (Marloes) | University of Twente

My name is Marloes Levers. I’m a biomedical research technician and obtained my bachelor’s degree at Saxion Hogeschool Deventer in 2007. I started as a research technician in the group of Frank van Leeuwen at the laboratory of pediatric oncology at Radboud UMC in Nijmegen. After that I’ve worked at the Tissue Regeneration department at the UT and later for the spin-off company Materiomics.

Currently I work with human induced pluripotent stem cells, which we differentiate into neurons and culture on MEA's (multi electrode array's)

Medicine & Life Sciences

# Hypoxia
# In Vitro Techniques
# Memory Consolidation
# Stroke

Engineering & Materials Science

# Cell Death
# Chemical Activation
# Neurons
# Recovery

Faculty of Science and Technology (TNW), Clinical Neurophysiology (CNPH)

Cerina, M. , Levers, M., Keller, J. M. , & Frega, M. (2024). Neuroprotective role of lactate in a human in vitro model of the ischemic penumbra. Scientific reports, 14(1), Article 7973. Advance online publication. https://doi.org/10.1038/s41598-024-58669-5

Voogd, E. J. H. F. , Doorn, N. , Levers, M. R. , Hofmeijer, J. , & Frega, M. (2023). Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells. Journal of neural engineering, 20(6), 1741-2552. Article 066038. https://doi.org/10.1088/1741-2552/ad17f3

Taxis Di Bordonia E Valnigra, D. , Hassink, G. C. , Levers, M. R. , Frega, M. , Hofmeijer, J. , van Putten, M. J. A. M. , & Le Feber, J. (2022). The Association between Hypoxia-Induced Low Activity and Apoptosis Strongly Resembles That between TTX-Induced Silencing and Apoptosis. International journal of molecular sciences, 23(5), Article 2754. https://doi.org/10.3390/ijms23052754

Dias, I. , Levers, M. R. , Lamberti, M. , Hassink, G. C. , Van Wezel, R. , & Le Feber, J. (2021). Consolidation of memory traces in cultured cortical networks requires low cholinergic tone, synchronized activity and high network excitability. Journal of neural engineering, 18(4), Article 046051. https://doi.org/10.1088/1741-2552/abfb3f

Pires Monteiro, S. , Voogd, E. , Muzzi, L., De Vecchis, G., Mossink, B. , Levers, M. , Hassink, G. , van Putten, M. , Le Feber, J. , Hofmeijer, J. , & Frega, M. (2021). Neuroprotective effect of hypoxic preconditioning and neuronal activation in a in vitro human model of the ischemic penumbra. Journal of neural engineering, 18(3), Article 036016. https://doi.org/10.1088/1741-2552/abe68a

Muzzi, L. , Hassink, G. , Levers, M. R., Jansman, M. M. T. , Frega, M. , Hofmeijer, J. , van Putten, M. J. A. M. , & le Feber, J. (2019). Mild stimulation improves neuronal survival in an in-vitro model of the ischemic penumbra. Journal of neural engineering, 17(1), Article 016001. https://doi.org/10.1088/1741-2552/ab51d4

Pires Monteiro, S., Covelo, J. , Levers, M. , Hassink, G. , le Feber, J. , & Frega, M. (2019). Ischemic Stroke: Treatments to Improve Neuronal Functional Recovery in vitro. In B. Blobel, & M. Giacomini (Eds.), pHealth 2019 (Vol. 261, pp. 313-316). (Studies in health technology and informatics; Vol. 261). https://doi.org/10.3233/978-1-61499-975-1-313

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+31534895189 (secretary)

+31534895189 (if no answer)

m.r.levers@utwente.nl

Visiting Address

University of Twente
Faculty of Science and Technology
Technohal (building no. 18), room 3384
Hallenweg 5
7522NH Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Technohal 3384
P.O. Box 217
7500 AE Enschede
The Netherlands

Faculty of Science and Technology (TNW), Clinical Neurophysiology (CNPH)

University of Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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