My name is Marloes Levers. I’m a biomedical research technician and obtained my bachelor’s degree at Saxion Hogeschool Deventer in 2007. I started as a research technician in the group of Frank van Leeuwen at the laboratory of pediatric oncology at Radboud UMC in Nijmegen. After that I’ve worked at the Tissue Regeneration department at the UT and later for the spin-off company Materiomics.
Currently I work with human induced pluripotent stem cells, which we differentiate into neurons and culture on MEA's (multi electrode array's)
Expertise
Neuroscience
- Neuron
- In Vitro
- Brain
- Neuroprotective Agent
- Ischemic Stroke
- Cell Survival
- Neuroprotection
Biochemistry, Genetics and Molecular Biology
- Neuronal Activity
Organisations
Publications
2024
Hypothermia improves neuronal network recovery in a human-derived in vitro model of oxygen-deprivation (2024)PLoS ONE, 19(12). Article e0314913. Voogd, E. J. H. F., Thijs, M., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1371/journal.pone.0314913Neuroprotective role of lactate in a human in vitro model of the ischemic penumbra (2024)Scientific reports, 14(1). Article 7973. Cerina, M., Levers, M., Keller, J. M. & Frega, M.https://doi.org/10.1038/s41598-024-58669-5Breaking the burst: Unveiling mechanisms behind fragmented network bursts in patient-derived neurons (2024)Stem cell reports, 19(11), 1583-1597. Doorn, N., Voogd, E. J. H. F., Levers, M. R., van Putten, M. J. A. M. & Frega, M.https://doi.org/10.1016/j.stemcr.2024.09.001
2023
Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells (2023)Journal of neural engineering, 20(6), 1741-2552. Article 066038. Voogd, E. J. H. F., Doorn, N., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1088/1741-2552/ad17f3
2022
The Association between Hypoxia-Induced Low Activity and Apoptosis Strongly Resembles That between TTX-Induced Silencing and Apoptosis (2022)International journal of molecular sciences, 23(5). Article 2754. Taxis Di Bordonia E Valnigra, D., Hassink, G. C., Levers, M. R., Frega, M., Hofmeijer, J., van Putten, M. J. A. M. & Le Feber, J.https://doi.org/10.3390/ijms23052754
2021
Consolidation of memory traces in cultured cortical networks requires low cholinergic tone, synchronized activity and high network excitability (2021)Journal of neural engineering, 18(4). Article 046051. Dias, I., Levers, M. R., Lamberti, M., Hassink, G. C., Van Wezel, R. & Le Feber, J.https://doi.org/10.1088/1741-2552/abfb3fNeuroprotective effect of hypoxic preconditioning and neuronal activation in a in vitro human model of the ischemic penumbra (2021)Journal of neural engineering, 18(3). Article 036016. Pires Monteiro, S., Voogd, E., Muzzi, L., De Vecchis, G., Mossink, B., Levers, M., Hassink, G., van Putten, M., Le Feber, J., Hofmeijer, J. & Frega, M.https://doi.org/10.1088/1741-2552/abe68a
Research profiles
Address
University of Twente
Technohal (building no. 18), room 3384
Hallenweg 5
7522 NH Enschede
Netherlands
University of Twente
Horst Complex (building no. 20), room ZH188
De Horst 2
7522 LW Enschede
Netherlands
University of Twente
Technohal 3384
P.O. Box 217
7500 AE Enschede
Netherlands
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