M.R. Levers BSc | People Pages: Find employees & contact details | University of Twente

My name is Marloes Levers. I’m a biomedical research technician and obtained my bachelor’s degree at Saxion Hogeschool Deventer in 2007. I started as a research technician in the group of Frank van Leeuwen at the laboratory of pediatric oncology at Radboud UMC in Nijmegen. After that I’ve worked at the Tissue Regeneration department at the UT and later for the spin-off company Materiomics.

Currently I work with human induced pluripotent stem cells, which we differentiate into neurons and culture on MEA's (multi electrode array's). And with rodent cortical cells.

Expertise

Neuroscience
- In Vitro
- Stem Cell
- Brain Ischemia
- Neuroprotective Agent
- Neuronal Activity
- Cerebrovascular Accident
- Enhancer Region
- N-Methyl-D-Aspartic Acid

Organisations

Publications

2025

Does sex matter in neurons’ response to hypoxic stress? (2025)Journal of Stroke & Cerebrovascular Diseases, 34(11). Article 108444. Voogd, E. J. H. F., Levers, M. R., Hofmeijer, J., Frega, M. & van Putten, M. J. A. M.https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108444

2024

Hypothermia improves neuronal network recovery in a human-derived in vitro model of oxygen-deprivation (2024)PLoS ONE, 19(12). Article e0314913. Voogd, E. J. H. F., Thijs, M., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1371/journal.pone.0314913Neuroprotective role of lactate in a human in vitro model of the ischemic penumbra (2024)Scientific reports, 14(1). Article 7973. Cerina, M., Levers, M., Keller, J. M. & Frega, M.https://doi.org/10.1038/s41598-024-58669-5Breaking the burst: Unveiling mechanisms behind fragmented network bursts in patient-derived neurons (2024)Stem cell reports, 19(11), 1583-1597. Doorn, N., Voogd, E. J. H. F., Levers, M. R., van Putten, M. J. A. M. & Frega, M.https://doi.org/10.1016/j.stemcr.2024.09.001

2023

Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells (2023)Journal of neural engineering, 20(6), 1741-2552. Article 066038. Voogd, E. J. H. F., Doorn, N., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1088/1741-2552/ad17f3

2022

The Association between Hypoxia-Induced Low Activity and Apoptosis Strongly Resembles That between TTX-Induced Silencing and Apoptosis (2022)International journal of molecular sciences, 23(5). Article 2754. Taxis Di Bordonia E Valnigra, D., Hassink, G. C., Levers, M. R., Frega, M., Hofmeijer, J., van Putten, M. J. A. M. & Le Feber, J.https://doi.org/10.3390/ijms23052754

2021

Consolidation of memory traces in cultured cortical networks requires low cholinergic tone, synchronized activity and high network excitability (2021)Journal of neural engineering, 18(4). Article 046051. Dias, I., Levers, M. R., Lamberti, M., Hassink, G. C., Van Wezel, R. & Le Feber, J.https://doi.org/10.1088/1741-2552/abfb3f

Research profiles

Address

University of Twente

Technohal (building no. 18), room 3384
Hallenweg 5
7522 NH Enschede
Netherlands

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University of Twente

Horst Complex (building no. 20), room ZH188
De Horst 2
7522 LW Enschede
Netherlands

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Organisations