Expertise
Medicine and Dentistry
- Cartilage
- Chondrocyte
- Cells
- Mesenchymal Stem Cell
- Culture
- In Vitro
Biochemistry, Genetics and Molecular Biology
- Stem Cell
- Stromal Cell
Organisations
Ancillary activities
- Hy2CareFounder of Hy2Care b.v.
- Hy2Care b.v.member supervisory board of Hy2Care
- Karperien Holding b.v.Management of Karperien Holding
- LipoCoat b.v.member of scientific advisory committee of LipoCoat b.v.
- Orthros MedicalFounder and non-executive CSO of Orthros Medical
- Orthros Medical b.v.Founder and non executive CSO of Orthros Medical
- Saxionguest lecturer at Saxion University of Applied Sciences
- academia.eduassociate editor Academia.edu section applied biology
Publications
2026
A Synovium-on-Chip Platform to Study Multicellular Interactions in Arthritis (2026)Advanced healthcare materials, 15(15). Article e04857. Spoelstra, L. R., Semmekrot, F. R., Araújo-Gomes, N., Wijnperle, D., Helsen, M. M. A., Van Den Bosch, M. H. J., Segerink, L. I., Le Gac, S. & Karperien, M.https://doi.org/10.1002/adhm.202504857Bioluminescence-based biosensing of NF-ĪŗB activity for osteoarthritis drug screening in a cartilage-on-chip model (2026)Biosensors & Bioelectronics: X, 30. Article 100786 (E-pub ahead of print/First online). Gudi, S., Araújo-Gomes, N., Conceição, F., van den Akker, G., Welting, T., Narcisi, R., Karperien, M. & Moreira Teixeira, L.https://doi.org/10.1016/j.biosx.2026.100786Non-oral tissue regeneration, angiogenesis, and healing with enamel matrix derivative (2026)Academia Biology, 4(1). Zada, O., Serrano-Larrea, C., Karperien, M. & Veen, E. J. D.https://doi.org/10.20935/AcadBiol8227Sex-related differences in femorotibial cartilage thickness: A matched pair analysis (2026)Annals of Anatomy, 266. Article 152824 (E-pub ahead of print/First online). Spoelder, N., Turmezei, T. D., Kessler, D. A., Mackay, J. W., Mastbergen, S. C., Karperien, M., Jansen, M. P. & Eckstein, F.https://doi.org/10.1016/j.aanat.2026.152824Guiding cell behaviour via intracellular crowding (2026)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Meteling, M. A. W.https://doi.org/10.3990/1.9789036570107Tailoring human joint-on-a-chip: From biological principles, materials, to disease modeling (2026)Materials Today Bio, 36. Article 102549. Wang, X., Ye Ong, L. J., Karperien, M. & Wen, C.https://doi.org/10.1016/j.mtbio.2025.102549
2025
A Quantitative Printability Framework for Programmable Assembly of PreāVascular Patterns via LaserāInduced Forward Transfer (2025)Advanced healthcare materials. Article e03665 (E-pub ahead of print/First online). Bosmans, C., Ginés Rodriguez, N., Hernández, U. J. G., Rivas, D. F., Karperien, M., Malda, J., Teixeira, L. M., Levato, R. & Leijten, J.https://doi.org/10.1002/adhm.202503665Automated routing for fluidic and pneumatic channels in standardized microfluidic platforms using CAD software (2025)[Contribution to conference › Poster] 29th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Micro-Total Analysis Systems, µTAS 2025. Spoelstra, L. R., Kramer, M., Karperien, M., Le Gac, S. & Segerink, L.Aqueous two-phase system enabled advances for biofabrication (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Becker, M. L.https://doi.org/10.3990/1.9789036568265Novel strategies to encode engineered living matter with self-feeding properties (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Gurian, M.https://doi.org/10.3990/1.9789036568302
Research profiles
Courses academic year 2026/2027
Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses academic year 2025/2026
- 193640999 - Internship BME
- 193650999 - Masters Assignment
- 201300196 - Clinical Specialization Internship
- 201400272 - Capita Selecta BME TNW-DBE
- 201800288 - Introduction to Bioengineering Techn.
- 202001586 - Elective course (Elders UT) 1
- 202001587 - Elective course (Elders UT) 2
- 202400231 - Cell Biology
- 202400311 - Cell-Material Interactions
- 202400318 - M12 BSc Assignment BMT
- 202400747 - Elective course (Elders UT) 3
- 202500335 - Project: Creating Biological Tissues
- 202500336 - Applied Cell Biology
Courses academic year 2024/2025
- 193640999 - Internship BME
- 193650999 - Masters Assignment
- 201300196 - Clinical Specialization Internship
- 201400272 - Capita Selecta BME TNW-DBE
- 201800288 - Introduction to Bioengineering Techn.
- 201900224 - Elective course (Elders UT)
- 202001586 - Elective course (Elders UT) 1
- 202001587 - Elective course (Elders UT) 2
- 202400231 - Cell Biology
- 202400255 - Project: Creating Biological Tissues
- 202400257 - Applied Cell Biology
- 202400310 - Nanoparticle Cell Interactions
- 202400311 - Cell-Material Interactions
- 202400318 - M12 BSc Assignment BMT
- 202400720 - SmartBio
- 202400747 - Elective course (Elders UT) 3
- 202400804 - Master Thesis Project EE - BMW
Address

University of Twente
Horst Complex (building no. 20), room ZH143
De Horst 2
7522 LW Enschede
Netherlands
University of Twente
Horst Complex ZH143
P.O. Box 217
7500 AE Enschede
Netherlands