dr.ir. N. Bosschaart (Nienke)

I am an Associate Professor in Biomedical Photonic Imaging. My research focuses on the development of optical diagnostic tools for mother and child care. I am working on two major research lines:

1. Noninvasive blood analysis in newborns

2. Human milk and lactation

For more info about Nienke Bosschaart on the 'Featured Scientists' page, click below:

Medicine & Life Sciences

# Bilirubin
# Optical Coherence Tomography

Physics & Astronomy

# Milk
# Tomography

Engineering & Materials Science

# Hemoglobin
# Human Milk
# Optical Tomography
# Scattering

Faculty of Science and Technology (TNW), Biomedical Photonic Imaging (BMPI)

I am an Associate Professor in Biomedical Photonic Imaging. My research focuses on the development of optical diagnostic tools for mother and child care. I am working on two major research lines:

1. Noninvasive blood analysis in newborns

2. Human milk and lactation

Bosschaart, N. , de Wolf, J. R. , Schoustra, S. M., van der Hoek, M., Leproux, A., Abdalsalam, O., Chen, W. P., McLaren, C. E., Tromberg, B. J., & O’Sullivan, T. D. (2021). Diffuse optical spectroscopic imaging of the human lactating breast. In European Conferences on Biomedical Optics, ECBO 2021 [ETu3C.1] (Optics InfoBase Conference Papers). The Optical Society. https://doi.org/10.1117/12.2615233

Cuartas-Vélez, C. , Veenstra, C. , Kruitwagen, S. , Petersen, W. , & Bosschaart, N. (2021). Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography. In European Conferences on Biomedical Optics, ECBO 2021 [EW3C.6] (Optics InfoBase Conference Papers). The Optical Society.

de Wolf, J. R. , Lenferink, A. T. M. , Otto, C. , & Bosschaart, N. (2021). Changes in human milk lipid composition and conformational state during a single breastfeed. In E. Beaurepaire, A. Ben-Yakar, & Y. Park (Eds.), European Conferences on Biomedical Optics, ECBO 2021: Advances in Microscopic Imaging III [ETu2A.26] (SPIE Conference Proceedings; Vol. 11922). The Optical Society. https://doi.org/10.1117/12.2615815

Dam-Vervloet, A. J. , Bosschaart, N., van Straaten, H. L. M., Poot, L., & Hulzebos, C. V. (2021). Irradiance footprint of phototherapy devices: a comparative study. Pediatric Research. https://doi.org/10.1038/s41390-021-01795-x

de Wolf, J. R., Lenferink, A. , Lenferink, A. , Otto, C. , & Bosschaart, N. (2021). Evaluation of the changes in human milk lipid composition and conformational state with Raman spectroscopy during a breastfeed. Biomedical optics express, 12(7), 3934-3947. https://doi.org/10.1364/BOE.427646

Cuartas-Vélez, C. , Veenstra, C. , Kruitwagen, S. , Petersen, W. , & Bosschaart, N. (2021). Optical density based quantification of total haemoglobin concentrations with spectroscopic optical coherence tomography. Scientific reports, 11(1), [8680]. https://doi.org/10.1038/s41598-021-88063-4

Arik, Y. B. , Buijsman, W. , Loessberg-Zahl, J. T. , Cuartas Velez, C. A. , Veenstra, C., Logtenberg, S., Grobbink, A. M. , Bergveld, P., Gagliardi, G., den Hollander, A. I. , Bosschaart, N. , van den Berg, A. , Passier, R. , & van der Meer, A. (2021). Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant readouts for tissue permeability and vascular structure. Lab on a chip, 21(2), 272-283. https://doi.org/10.1039/d0lc00639d

Dam-Vervloet, A. J., van Erk, M. D., Doorn, N., Lip, S. G. J., Timmermans, N. A., Vanwinsen, L., de Boer, F. A., van Straaten, H. L. M. , & Bosschaart, N. (2021). Inter-device reproducibility of transcutaneous bilirubin meters. Pediatric Research, 89(4), 770-775. https://doi.org/10.1038/s41390-020-01118-6

Veenstra, C. , Every, D. E. , Petersen, W., van Goudoever, J. B. , Steenbergen, W. , & Bosschaart, N. (2020). Dependency of the optical scattering properties of human milk on casein content and common sample preparation methods. Journal of biomedical optics, 25(4), [045001]. https://doi.org/10.1117/1.JBO.25.4.045001

Veenstra, C. (2020). Visible light spectroscopic optical coherence tomography for applications in neonatal healthcare. University of Twente. https://doi.org/10.3990/1.9789036549875

van Erk, M. D., Dam-Vervloet, A. J., de Boer, F. A., Boomsma, M. F., Straaten, H. V. , & Bosschaart, N. (2019). How skin anatomy influences transcutaneous bilirubin determinations: an in vitro evaluation. Pediatric Research, 86(4), 471-477. https://doi.org/10.1038/s41390-019-0471-z

Veenstra, C. , Kruitwagen, S., Groener, D. , Petersen, W. , Steenbergen, W. , & Bosschaart, N. (2019). Quantification of total haemoglobin concentrations in human whole blood by spectroscopic visible-light optical coherence tomography. Scientific reports, 9(1), [15115]. https://doi.org/10.1038/s41598-019-51721-9

Veenstra, C., Lenferink, A. , Petersen, W. , Steenbergen, W. , & Bosschaart, N. (2019). Optical properties of human milk. Biomedical optics express, 10(8), 4059-4074. [361809]. https://doi.org/10.1364/BOE.10.004059

Bosschaart, N., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O'Sullivan, T. D. (2019). Diffuse optical spectroscopic imaging for the investigation of human lactation physiology: a case study on mammary involution. Journal of biomedical optics, 24(5), 056006. [056006]. https://doi.org/10.1117/1.JBO.24.5.056006

van der Hoek, M., den Haan, L., Kaspers, A. , Steenbergen, W. , & Bosschaart, N. (2019). Cutaneous perfusion of the human lactating breast: a pilot study with laser Doppler perfusion monitoring. Physiological measurement, 40(5), [05NT01]. https://doi.org/10.1088/1361-6579/ab1ad7

Veenstra, C. , Petersen, W. , Vellekoop, I. M. , Steenbergen, W. , & Bosschaart, N. (2018). Spatially confined quantification of bilirubin concentrations by spectroscopic visible-light optical coherence tomography. Biomedical optics express, 9(8), 3581-3589. [327320]. https://doi.org/10.1364/BOE.9.003581

Veenstra, C., Jeurink, L. , Vellekoop, I. , & Bosschaart, N. (2017). Spectroscopic optical coherence tomography for absorption quantification in the blue wavelength region. Abstract from SPIE Photonics West 2017, San Francisco, California, United States.

Veenstra, C., Jeurink, L. , Vellekoop, I. M. , & Bosschaart, N. (2017). Quantification of bilirubin concentrations by visible light spectroscopic optical coherence tomography. Abstract from European Conferences on Biomedical Optics, EBCO 2017, Munster, Germany.

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Bachelor

Master

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