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dr.ir. N. Bosschaart (Nienke)

Associate Professor

About Me

Nienke Bosschaart is an adjunct professor in Biomedical Photonic Imaging with a focus on innovative diagnostic techniques for mother and child care. Her research aims to develop novel methods for i) noninvasive blood analysis in newborns and ii) human lactation research. Nienke Bosschaart has been awarded with an ERC Starting grant from the European Research Council (2022), as well as a Vidi (2021) and Veni (2014) grant from the Dutch Research Council. She graduated in Biomedical Engineering at the University of Twente (2007) and received her PhD at the department of Biomedical Engineering and Physics of the Amsterdam UMC (2012) under the supervision of Prof.dr. Ton van Leeuwen and Prof.dr. Maurice Aalders. Since 2015, she works at the Biomedical Photonic Imaging group of the University of Twente.

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Expertise

Medicine & Life Sciences
Bilirubin
Optical Coherence Tomography
Physics & Astronomy
Milk
Tomography
Engineering & Materials Science
Hemoglobin
Human Milk
Optical Tomography
Tissue

Research

My research focuses on the development of optical diagnostic tools for mother and child care. I am working on two major research themes:

1. Noninvasive blood analysis

2. Human milk and lactation

 

Publications

Recent
Bosschaart, N. , de Wolf, J. R. , Schoustra, S. M., van der Hoek, M., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O'Sullivan, T. D. (2021). Diffuse optical spectroscopic imaging of the human lactating breast. In D. Contini, Y. Hoshi, & T. D. O'Sullivan (Eds.), Diffuse Optical Spectroscopy and Imaging VIII [119200N] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11920). SPIE Press. https://doi.org/10.1117/12.2615233
Cuartas-Vélez, C. , Veenstra, C. , Kruitwagen, S. , Petersen, W. , & Bosschaart, N. (2021). Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography. In B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (Eds.), Optical Coherence Imaging Techniques and Imaging in Scattering Media IV [119240R] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11924). SPIE Press. https://doi.org/10.1117/12.2616058
Bosschaart, N. , de Wolf, J. R. , Schoustra, S. M., van der Hoek, M., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O’Sullivan, T. D. (2021). Diffuse optical spectroscopic imaging of the human lactating breast. In European Conferences on Biomedical Optics, ECBO 2021 [ETu3C.1] The Optical Society. https://opg.optica.org/abstract.cfm?uri=ECBO-2021-ETu3C.1
de Wolf, J. R., Lenferink, A. , Lenferink, A. T. M. , Otto, C. , & Bosschaart, N. (2021). Changes in human milk lipid composition and conformational state during a single breastfeed. In E. Beaurepaire, A. Ben-Yakar, & Y. Park (Eds.), European Conferences on Biomedical Optics, ECBO 2021: Advances in Microscopic Imaging III [ETu2A.26] (SPIE Conference Proceedings; Vol. 11922). The Optical Society. https://doi.org/10.1117/12.2615815
Dam-Vervloet, A. J. , Bosschaart, N., van Straaten, H. L. M., Poot, L., & Hulzebos, C. V. (2021). Irradiance footprint of phototherapy devices: a comparative study. Pediatric Research. https://doi.org/10.1038/s41390-021-01795-x
Dam-Vervloet, A. J., van Erk, M. D. , Doorn, N., Lip, S. G. J., Timmermans, N. A., Vanwinsen, L., de Boer, F. A., van Straaten, H. L. M. , & Bosschaart, N. (2021). Inter-device reproducibility of transcutaneous bilirubin meters. Pediatric Research, 89(4), 770-775. https://doi.org/10.1038/s41390-020-01118-6
van Erk, M. D., Dam-Vervloet, A. J., de Boer, F. A., Boomsma, M. F., Straaten, H. V. , & Bosschaart, N. (2019). How skin anatomy influences transcutaneous bilirubin determinations: an in vitro evaluation. Pediatric Research, 86(4), 471-477. https://doi.org/10.1038/s41390-019-0471-z
Bosschaart, N., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O'Sullivan, T. D. (2019). Diffuse optical spectroscopic imaging for the investigation of human lactation physiology: a case study on mammary involution. Journal of biomedical optics, 24(5), 056006. [056006]. https://doi.org/10.1117/1.JBO.24.5.056006
Veenstra, C., Jeurink, L. , Vellekoop, I. , & Bosschaart, N. (2017). Spectroscopic optical coherence tomography for absorption quantification in the blue wavelength region. Abstract from SPIE Photonics West 2017, San Francisco, California, United States.
Veenstra, C., Jeurink, L. , Vellekoop, I. M. , & Bosschaart, N. (2017). Quantification of bilirubin concentrations by visible light spectroscopic optical coherence tomography. Abstract from European Conferences on Biomedical Optics, EBCO 2017, Munster, Germany.

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Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Horst Complex (building no. 20), room ZH262
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst Complex  ZH262
P.O. Box 217
7500 AE Enschede
The Netherlands