About Me
Nienke Bosschaart is an adjunct professor in Biomedical Photonic Imaging with a focus on innovative diagnostic techniques for mother and child care. Her research aims to develop novel methods for i) noninvasive blood analysis in newborns and ii) human lactation research. Nienke Bosschaart has been awarded with an ERC Starting grant from the European Research Council (2022), as well as a Vidi (2021) and Veni (2014) grant from the Dutch Research Council. She graduated in Biomedical Engineering at the University of Twente (2007) and received her PhD at the department of Biomedical Engineering and Physics of the Amsterdam UMC (2012) under the supervision of Prof.dr. Ton van Leeuwen and Prof.dr. Maurice Aalders. Since 2015, she works at the Biomedical Photonic Imaging group of the University of Twente.
For more info about Nienke Bosschaart on the 'Featured Scientists' page, click below:
Expertise
Medicine & Life Sciences
# Bilirubin
# Optical Coherence Tomography
Physics & Astronomy
# Milk
# Tomography
Engineering & Materials Science
# Hemoglobin
# Human Milk
# Optical Tomography
# Tissue
Organisations
Research
My research focuses on the development of optical diagnostic tools for mother and child care. I am working on two major research themes:
Publications
Recent
Morsink, C. F., Dam-Vervloet, A. J., Krommendijk, M. E., Kaya, M.
, Cuartas-Vélez, C.
, Knop, T.
, Francis, K. J.
, & Bosschaart, N. (2023).
Design and characterization of color printed polyurethane films as biomedical phantom layers.
Biomedical optics express,
14(9), 4485-4506.
https://doi.org/10.1364/BOE.491695
Cuartas Velez, C. A. (2023).
Visible-light spectroscopic optical coherence tomography: applications and technology. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente.
https://doi.org/10.3990/1.9789036557368
Dam-Vervloet, A. J., de Boer, F. A., Nijholt, I. M., Poot, L.
, Bosschaart, N., & van Straaten, H. L. M. (2022).
Quantification of cephalocaudal progression of jaundice in preterm infants.
Pediatric Research.
https://doi.org/10.1038/s41390-022-02396-y
Bosschaart, N.
, & Manohar, S. (2022).
New directions for optical breast imaging and sensing: Multimodal cancer imaging and lactation research.
Current Opinion in Biomedical Engineering,
22, [100380].
https://doi.org/10.1016/j.cobme.2022.100380
Dam-Vervloet, A. J.
, Bosschaart, N., van Straaten, H. L. M., Poot, L., & Hulzebos, C. V. (2022).
Irradiance footprint of phototherapy devices: a comparative study.
Pediatric Research,
92, 453-458.
https://doi.org/10.1038/s41390-021-01795-x
Bosschaart, N., de Wolf, J. R.
, Schoustra, S. M., van der Hoek, M., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O'Sullivan, T. D. (2021).
Diffuse optical spectroscopic imaging of the human lactating breast. In D. Contini, Y. Hoshi, & T. D. O'Sullivan (Eds.),
Diffuse Optical Spectroscopy and Imaging VIII [119200N] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11920). SPIE.
https://doi.org/10.1117/12.2615233
Cuartas-Vélez, C.
, Veenstra, C.
, Kruitwagen, S.
, Petersen, W.
, & Bosschaart, N. (2021).
Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography. In B. J. Vakoc, M. Wojtkowski, & Y. Yasuno (Eds.),
Optical Coherence Imaging Techniques and Imaging in Scattering Media IV [119240R] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11924). SPIE.
https://doi.org/10.1117/12.2616058
Bosschaart, N., de Wolf, J. R.
, Schoustra, S. M., van der Hoek, M., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O’Sullivan, T. D. (2021).
Diffuse optical spectroscopic imaging of the human lactating breast. In
European Conferences on Biomedical Optics, ECBO 2021 [ETu3C.1] The Optical Society.
https://opg.optica.org/abstract.cfm?uri=ECBO-2021-ETu3C.1
Cuartas-Vélez, C.
, Veenstra, C.
, Kruitwagen, S.
, Petersen, W.
, & Bosschaart, N. (2021).
Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography. In
European Conferences on Biomedical Optics, ECBO 2021 [EW3C.6] The Optical Society.
https://opg.optica.org/abstract.cfm?URI=ECBO-2021-EW3C.6
de Wolf, J. R., Lenferink, A., Lenferink, A. T. M.
, Otto, C.
, & Bosschaart, N. (2021).
Changes in human milk lipid composition and conformational state during a single breastfeed. In E. Beaurepaire, A. Ben-Yakar, & Y. Park (Eds.),
European Conferences on Biomedical Optics, ECBO 2021: Advances in Microscopic Imaging III [ETu2A.26] (SPIE Conference Proceedings; Vol. 11922). The Optical Society.
https://doi.org/10.1117/12.2615815
de Wolf, J. R., Lenferink, A., Lenferink, A.
, Otto, C.
, & Bosschaart, N. (2021).
Evaluation of the changes in human milk lipid composition and conformational state with Raman spectroscopy during a breastfeed.
Biomedical optics express,
12(7), 3934-3947.
https://doi.org/10.1364/BOE.427646
Arik, Y. B., Buijsman, W.
, Loessberg-Zahl, J. T.
, Cuartas Velez, C. A.
, Veenstra, C., Logtenberg, S., Grobbink, A. M.
, Bergveld, P., Gagliardi, G., den Hollander, A. I.
, Bosschaart, N.
, van den Berg, A.
, Passier, R.
, & van der Meer, A. (2021).
Microfluidic organ-on-a-chip model of the outer blood–retinal barrier with clinically relevant readouts for tissue permeability and vascular structure.
Lab on a chip,
21(2), 272-283.
https://doi.org/10.1039/d0lc00639d
Dam-Vervloet, A. J., van Erk, M. D.
, Doorn, N., Lip, S. G. J., Timmermans, N. A., Vanwinsen, L., de Boer, F. A., van Straaten, H. L. M.
, & Bosschaart, N. (2021).
Inter-device reproducibility of transcutaneous bilirubin meters.
Pediatric Research,
89(4), 770-775.
https://doi.org/10.1038/s41390-020-01118-6
Veenstra, C., Every, D. E.
, Petersen, W., van Goudoever, J. B.
, Steenbergen, W.
, & Bosschaart, N. (2020).
Dependency of the optical scattering properties of human milk on casein content and common sample preparation methods.
Journal of biomedical optics,
25(4), [045001].
https://doi.org/10.1117/1.JBO.25.4.045001
Veenstra, C. (2020).
Visible light spectroscopic optical coherence tomography for applications in neonatal healthcare. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente.
https://doi.org/10.3990/1.9789036549875
van Erk, M. D., Dam-Vervloet, A. J., de Boer, F. A., Boomsma, M. F., Straaten, H. V.
, & Bosschaart, N. (2019).
How skin anatomy influences transcutaneous bilirubin determinations: an in vitro evaluation.
Pediatric Research,
86(4), 471-477.
https://doi.org/10.1038/s41390-019-0471-z
Veenstra, C.
, Kruitwagen, S., Groener, D.
, Petersen, W.
, Steenbergen, W.
, & Bosschaart, N. (2019).
Quantification of total haemoglobin concentrations in human whole blood by spectroscopic visible-light optical coherence tomography.
Scientific reports,
9(1), [15115].
https://doi.org/10.1038/s41598-019-51721-9
Veenstra, C., Lenferink, A.
, Petersen, W.
, Steenbergen, W.
, & Bosschaart, N. (2019).
Optical properties of human milk.
Biomedical optics express,
10(8), 4059-4074. [361809].
https://doi.org/10.1364/BOE.10.004059
Bosschaart, N., Leproux, A., Abdalsalam, O., Chen, W-P., McLaren, C. E., Tromberg, B. J., & O'Sullivan, T. D. (2019).
Diffuse optical spectroscopic imaging for the investigation of human lactation physiology: a case study on mammary involution.
Journal of biomedical optics,
24(5), 056006. [056006].
https://doi.org/10.1117/1.JBO.24.5.056006
van der Hoek, M., den Haan, L., Kaspers, A.
, Steenbergen, W.
, & Bosschaart, N. (2019).
Cutaneous perfusion of the human lactating breast: a pilot study with laser Doppler perfusion monitoring.
Physiological measurement,
40(5), [05NT01].
https://doi.org/10.1088/1361-6579/ab1ad7
Veenstra, C.
, Petersen, W.
, Vellekoop, I. M.
, Steenbergen, W.
, & Bosschaart, N. (2018).
Spatially confined quantification of bilirubin concentrations by spectroscopic visible-light optical coherence tomography.
Biomedical optics express,
9(8), 3581-3589. [327320].
https://doi.org/10.1364/BOE.9.003581
UT Research Information System
Google Scholar Link
Affiliated Study Programmes
Bachelor
Master
Courses Academic Year 2023/2024
Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.
Courses Academic Year 2022/2023
Current Projects
-
Noninvasive blood analysis
In this project, we use optical spectroscopy and visible light sOCT (spectroscopic optical coherence tomography) to noninvasively quantify the concentrations of bilirubin and hemoglobin in the blood of newborns.
-
Human milk and lactation
In this project, we use our optical technologies to learn more about the composition of breast milk and the physiology of lactation.
In the press
Videos
- Universiteit van Nederland, Waarom lukt borstvoeding soms niet?, October (2022)
Books
- Dolf Jansen en Jim Jansen, PromovendA tot Z, ISBN: 9789464042085, Fontaine Uitgevers, November (2022)
Articles
- Campus Magazine, De UT-pijler: Gezondheid van vrouwen, Michaela Nesvarova, August (2022)
- Ouders van Nu, Nieuw in de maak: sensor die meet hoe veel borstvoeding je baby binnenkrijgt, Carin Röst, August (2022)
- Het Parool, Nienke Bosschaart: ‘Op een congres over borstvoeding in Florence beleefde ik een aha-moment’, Jim Jansen, August (2022)
- Algemeen Dagblad, New Scientist, We weten bitter weinig over moedermelk, Jim Jansen, April (2022)
- Nederlands Dagblad, Wat gebeurt er in de borst tijdens het voeden? Dat weet (nu nog) niemand, Eymeke Verhoeven, January (2022)
- U-Today, Methods to help women breastfeed, Michaela Nesvarova, January (2022)
- SPIE International Society for Optics and Photonics, Women in Optics planner – featured page, Alison Walker (2022)
- University of Twente, ERC Starting Grant voor drie UT-wetenschappers, January (2022)
- European Research Council, ERC Starting Grants – Project Highlights, Pioneering methods to help women breastfeed, January (2022)
- University of Twente, Drie UT-onderzoekers ontvangen NWO Vidi-financiering, July (2021)
- NWO, NWO-Vidi van 800.000 euro voor 78 ervaren onderzoekers, July (2021)
- U-Today, Aan de Borreltafel: Bijna iedereen vindt babietjes leuk, Enith Vlooswijk, July (2021)
- University of Twente, Featured Scientists: Dr.ir. Nienke Bosschaart, Michaela Nesvarova, August (2020)
- U-Today, Moedermelk ontwikkelde zich enorm in miljoenen jaren evolutie, Ditta op den Dries, March (2019)
- University of Twente, Zeven vrouwelijke UT-wetenschappers in Viva 400, October (2018)
- De Ingenieur: Ingenieurstalent, De Babybeamer, Marc Seijlhouwer, September (2018)
- De Maatschappij, Jaarcongres 2018 met een Koninklijk tintje, Pierre van Aalst, September (2018)
- University of Twente, Studentgedreven werkbezoek onderwijsminister Van Engelshoven aan Universiteit Twente, February (2018)
- U-Today, Rising Star Nienke Bosschaart: All about babies, Michaela Nesvarova, May (2017)
- MIRA mag, Sparring partners: Painless optic ‘prick’, Kees de Rijk, issue 2 (2016)
- Medisch Contact, Meten zonder prikken, Danka Stuijver, January (2015)
- RTV Noord Holland radio, interview on Veni grant award in ‘NH Spitstijd’, Aart van Eldik, 29 July (2014)
- NWO, Veni 2014, July (2014)
- Kennislink, Slimme techniek spoort pijnloos geelzucht op, Robert Visscher, 16 October (2013)
- De Telegraaf, Bloedonderzoek zonder prikken, 12 October (2013)
- Technologiestichting STW – Technologisch Toptalent, Meten met licht, Sybe Rispens, vol. 9 (2013)
- AMC Magazine, Babies meten zonder prikken, Anne Koeleman, issue 9 (2013)
- Technisch Weekblad, Bloedwaarden meten zonder prikken, Marianne Vincken, issue 41 (2013)
Contact Details
Visiting Address
University of Twente
Faculty of Science and Technology
Horst Complex
(building no. 20), room ZH262
De Horst 2
7522LW Enschede
The Netherlands
Mailing Address
University of Twente
Faculty of Science and Technology
Horst Complex
ZH262
P.O. Box 217
7500 AE Enschede
The Netherlands