Horst Complex

prof.dr.ir. N.J.J. Verdonschot (Nico)

Professor Implant Biomechanics
ET-BE-BDDP
Horst Complex W101
n.verdonschot@utwente.nl
+31534896472
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In 1988 I did my master thesis in Nijmegen at theĀ Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at theĀ Radboudumc Institute for Health SciencesĀ (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (seeĀ www.erc-biomechtools.eu).

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling

Expertise

  • Medicine and Dentistry

    • Total Knee Arthroplasty
    • Bone
    • Implant
    • Patient
    • Knee
    • Element
    • Magnetic Resonance Imaging
    • Measurement

Organisations

Ancillary activities

  • Atro Medical1
  • Exactechconsultant
  • Invibioconsultant

Publications

2025

Postoperative accuracy quantification of corrective osteotomies: Standardisation of Q3D-CT methodology (2025)European Journal of Trauma and Emergency Surgery, 51(1). Article 81. Tabernée Heijtmeijer, S. J. C., Meesters, A. M. L., Verdonschot, N. J. J., Jutte, P. C., Doornberg, J. N., Pijpker, P. A. J. & Kraeima, J.https://doi.org/10.1007/s00068-024-02684-8The effect of human bone morphology on sawing forces (2025)Journal of the mechanical behavior of biomedical materials, 172. Article 107185. Ramezani, A., Tamadon, I., Meinders, Q., van Emden, M., Verdonschot, N. & Tuijthof, G.https://doi.org/10.1016/j.jmbbm.2025.107185Dynamic CT-based assessment of ulnar-sided wrist kinematics in healthy participants using automated 3-D analysis (2025)Journal of Hand Surgery: European Volume (E-pub ahead of print/First online). Teule, E., Wolters, J., Verdonschot, N., Hummelink, S. & van der Heijden, B.https://doi.org/10.1177/17531934251397297The Importance of Modeling Pressā€Fit to Accurately Evaluate Interfacial Micromotion as an Indicator of Primary Stability in Uncemented Arthroplasty (2025)Journal of orthopaedic research (E-pub ahead of print/First online). Johnson, J. E., Verdonschot, N., Janssen, D. & Anderson, D. D.https://doi.org/10.1002/jor.70081Assessing Implant Stability in Cementless Femoral Components with Different Interference Fits (2025)Journal of orthopaedic research (E-pub ahead of print/First online). Sánchez, E., Schilling, C., Grupp, T. M., Giurea, A., Verdonschot, N. & Janssen, D.https://doi.org/10.1002/jor.70079Mechanical evaluation of the KneeReviver device under axial loading in knee joint distraction therapy for tibiofemoral osteoarthritis treatment: A cadaver study (2025)Journal of the mechanical behavior of biomedical materials, 170. Article 107098. Janssen, F., Bitter, T., Hanssen, E., van Roermund, P., Verdonschot, N. & Janssen, D.https://doi.org/10.1016/j.jmbbm.2025.107098Bone stress relaxation in press-fit femoral knee implant fixation: A combined experimental and computational analysis (2025)Journal of the mechanical behavior of biomedical materials, 169. Article 107067. Gersie, T., Bitter, T., Freeman, R., Verdonschot, N. & Janssen, D.https://doi.org/10.1016/j.jmbbm.2025.107067Artificial medial and lateral meniscus prostheses mimic kinematics of the native meniscus without affecting knee joint motion: A cadaveric study (2025)Journal of Experimental Orthopaedics, 12(3). Article e70379. van Minnen, B. S., Sturm, A. R., van der Veen, A. J., van de Groes, S. A. W., Verdonschot, N. & van Tienen, T. G.https://doi.org/10.1002/jeo2.70379A structured framework for standardized 3D leg alignment analysis: An international Delphi consensus study (2025)Knee surgery, sports traumatology, arthroscopy, 33(6), 2276-2292. Veerman, Q. W. T., Tuijthof, G. J. M., Verdonschot, N., Brouwer, R. W., Verdonk, P., van Haver, A., van der Veen, H. C., Pijpker, P. A. J., Heuvel, J. o. & Hoogeslag, R. A. G.https://doi.org/10.1002/ksa.12676Finite element analysis of primary stability in cementless tibial components with varying interference fits (2025)Clinical biomechanics, 126. Article 106539. Sánchez, E., Boot, M. R., Schilling, C., Grupp, T. M., Giurea, A., Verdonschot, N. & Janssen, D.https://doi.org/10.1016/j.clinbiomech.2025.106539

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University of Twente

Horst Complex (building no. 20), room W101
De Horst 2
7522 LW Enschede
Netherlands

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