prof.dr.ir. N.J.J. Verdonschot (Nico)

Professor Biomechanical Implants

About Me

In 1988 I did my master thesis in Nijmegen at the Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at the Radboudumc Institute for Health Sciences (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (see www.erc-biomechtools.eu).

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling


Knee Replacement Arthroplasties
Bone And Bones
Biomechanical Phenomena

Ancillary Activities

  • Exactech
    Consultancy to design a tibial component of a total knee replacment
  • Invibio Knees ltd
    Consultancy for design and testing of a PEEK knee
  • Politecnico di Milano
    geven van een cursus voor 1e jaars masterstudenten


Marra, M. A., Strzelczak, M., Heesterbeek, P. J. C., van de Groes, S. A. W., Janssen, D., Koopman, B. F. J. M., ... Wymenga, A. B. (2018). Flexing and downsizing the femoral component is not detrimental to patellofemoral biomechanics in posterior-referencing cruciate-retaining total knee arthroplasty. Knee surgery, sports traumatology, arthroscopy, 1-9. DOI: 10.1007/s00167-018-4900-z
Leijendekkers, R. A., Marra, M. A., Ploegmakers, M. J. M., Van Hinte, G., Frölke, J. P., Van De Meent, H., ... Verdonschot, N. (2018). Magnetic-resonance-imaging-based three-dimensional muscle reconstruction of hip abductor muscle volume in a person with a transfemoral bone-anchored prosthesis: A feasibility study. Physiotherapy Theory and Practice. DOI: 10.1080/09593985.2018.1453902
Leijendekkers, R. A., Marra, M. A., Kolk, S., Van Bon, G., Schreurs, B. W., Weerdesteyn, V., & Verdonschot, N. (2018). Gait symmetry and hip strength in women with developmental dysplasia following hip arthroplasty compared to healthy subjects: A cross-sectional study. PLoS ONE, 13(2), [e0193487]. DOI: 10.1371/journal.pone.0193487
Marra, M. A., Heskamp, L., Mul, K., Lassche, S., van Engelen, B. G. M., Heerschap, A., & Verdonschot, N. (2018). Specific muscle strength is reduced in facioscapulohumeral dystrophy: An MRI based musculoskeletal analysis. Neuromuscular disorders. DOI: 10.1016/j.nmd.2017.11.017
Van Susante, J. L. C., Verdonschot, N., Bom, L. P. A., Tomaszewski, P., Campbell, P., Ebramzadeh, E., & Schreurs, B. W. (2018). Lessons learnt from early failure of a patient trial with a polymer-on-polymer resurfacing hip arthroplasty. Acta orthopaedica, 89(1), 59-65. DOI: 10.1080/17453674.2017.1376526
Bitter, T., Khan, I., Marriott, T., Lovelady, E., Verdonschot, N., & Janssen, D. (2018). Finite element wear prediction using adaptive meshing at the modular taper interface of hip implants. Journal of the mechanical behavior of biomedical materials, 77, 616-623. DOI: 10.1016/j.jmbbm.2017.10.032
Schröder, F. F., Verdonschot, N. J. J., ten Haken, B., Peters, A., Vochteloo, A. J. H., Pakvis, D. F. M., & Huis in 't Veld, R. (2018). Low-field magnetic resonance imaging offers potential for measuring tibial component migration. Journal of Experimental Orthopaedics, 5(4). DOI: 10.1186/s40634-017-0116-2
Marra, M. A., Heesterbeek, P. J. C., van de Groes, S. A. W., Janssen, D. W., Koopman, H. F. J. M., Wymenga, A. B., & Verdonschot, N. J. J. (2017). Effect of referencing technique for the tibial slope in cruciate-retaining total knee arthroplasty. Journal of bone and joint surgery. British volume. Orthopaedic proceedings, 99-B(Suppl. 4), [139].
Marra, M. A., Strzelczak, M., van de Groes, S. A. W., Heesterbeek, P. J. C., Janssen, D. W., Koopman, H. F. J. M., ... Wymenga, A. B. (2017). The effect of flexion of the femoral component in TKA: A musculoskeletal simulation study. Abstract from European Knee Society Conference 2017, London, United Kingdom.

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Visiting Address

University of Twente
Faculty of Engineering Technology
Horst - Ring (building no. 21)
De Horst 2
7522LW  Enschede
The Netherlands

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University of Twente
P.O. Box 217
7500 AE Enschede
The Netherlands

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