prof.dr.ir. N.J.J. Verdonschot (Nico)

Professor Implant Biomechanics

About Me

In 1988 I did my master thesis in Nijmegen at the Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at the Radboudumc Institute for Health Sciences (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (see www.erc-biomechtools.eu).

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling


Engineering & Materials Science
Medicine & Life Sciences
Biomechanical Phenomena
Bone And Bones
Knee Replacement Arthroplasties

Ancillary Activities

  • Invibio and Exactech
  • Atro Medical


Tzanetis, P. (2024). Toward personalized total knee arthroplasty: Pre-planning the patient's optimal joint function. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036559355
Atallah, R., Reetz, D. , Verdonschot, N., De Kleuver, M., Frölke, J. P. M., & Leijendekkers, R. A. (2023). Have Surgery and Implant Modifications Been Associated With Reduction in Soft Tissue Complications in Transfemoral Bone-anchored Prostheses? Clinical orthopaedics and related research, 481(7), 1373-1384. https://doi.org/10.1097/CORR.0000000000002535
Imhauser, C. W., Baumann, A. P., Liu, X., Bischoff, J. E. , Verdonschot, N., Fregly, B. J., Elmasry, S. S., Abdollahi, N. N., Hume, D. R., Rooks, N. B., Schneider, M. T. Y., Zaylor, W., Besier, T. F., Halloran, J. P., Shelburne, K. B., & Erdemir, A. (2023). Reproducibility in modeling and simulation of the knee: Academic, industry, and regulatory perspectives. Journal of orthopaedic research, 41(12), 2569-2578. https://doi.org/10.1002/jor.25652
Soltanihafshejani, N., Peroni, F., Toniutti, S., Bitter, T., Tanck, E., Eggermont, F. , Verdonschot, N., & Janssen, D. (2023). The application of an isotropic crushable foam model to predict the femoral fracture risk. PLoS ONE, 18(7), 1-16. Article e0288776. Advance online publication. https://doi.org/10.1371/journal.pone.0288776

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Contact Details

Visiting Address

University of Twente
Faculty of Engineering Technology
Horst Complex (building no. 20), room W101
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Engineering Technology
Horst Complex  W101
P.O. Box 217
7500 AE Enschede
The Netherlands

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