Horst Complex

prof.dr.ir. N.J.J. Verdonschot (Nico)

Professor Implant Biomechanics
ET-BE-BDDP
Horst Complex W101
n.verdonschot@utwente.nl
+31534896472
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In 1988 I did my master thesis in Nijmegen at the Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at the Radboudumc Institute for Health Sciences (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (see www.erc-biomechtools.eu).

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling

Expertise

  • Medicine and Dentistry

    • Total Knee Arthroplasty
    • Bone
    • Implant
    • Patient
    • Knee
    • Element
    • Magnetic Resonance Imaging
    • Measurement

Organisations

Ancillary activities

  • Atro Medical1
  • Exactechconsultant
  • Invibioconsultant

Publications

2025

The effect of human bone morphology on sawing forces (2025)Journal of the mechanical behavior of biomedical materials, 172. Article 107185. Ramezani, A., Tamadon, I., Meinders, Q., van Emden, M., Verdonschot, N. & Tuijthof, G.https://doi.org/10.1016/j.jmbbm.2025.107185A structured framework for standardized 3D leg alignment analysis: An international Delphi consensus study (2025)Knee surgery, sports traumatology, arthroscopy, 33(6), 2276-2292. Veerman, Q. W. T., Tuijthof, G. J. M., Verdonschot, N., Brouwer, R. W., Verdonk, P., van Haver, A., van der Veen, H. C., Pijpker, P. A. J., Heuvel, J. o. & Hoogeslag, R. A. G.https://doi.org/10.1002/ksa.12676Reactive balance and stepping strategy in persons using a transfemoral prosthesis (2025)In I.S.P.O. 20th World Congress 2025: Stockholm Sweden, 16-19 June 2025: Abstract Book (pp. 146-146). Article 5.063. International Society for Prosthetics and Orthotics (ISPO). Kooiman, V., Weerdesteyn, V., Verdonschot, N. & Leijendekkers, R.Towards Deployable Implants: Conceptual Designs of a Novel Deployable Interposition Wrist Implant Using Origami, Scissor, And Sliding Block Mechanisms (2025)[Contribution to conference › Paper] 25th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, CAOS 2025. Boksebeld, M., Leverink, J., Flinkert, M., Tamadon, I., Ramezani, A., Verdonschot, N., Tuijthof, G. & Asseln, M.The MyFlex-ζ Foot: A Variable Stiffness ESR Ankle-Foot Prosthesis (2025)IEEE transactions on neural systems and rehabilitation engineering, 33, 653-663. Tabucol, J., Kooiman, V. G. M., Leopaldi, M., Leijendekkers, R., Selleri, G., Mellini, M., Verdonschot, N., Oddsson, M., Carloni, R., Zucchelli, A. & Brugo, T. M.https://doi.org/10.1109/TNSRE.2025.3534096AI-accelerated prediction of optimal implant alignment in total knee arthroplasty (2025)[Contribution to conference › Abstract] 10th Dutch Biomedical Engineering Conference, BME 2025. Verdonschot, N. J. J., ten Klooster, L. R., Tzanetis, P. & Wolterink, J. M.Are kinematic and ligament strain restoration interchangeable targets in total knee arthroplasty? (2025)[Contribution to conference › Abstract] 30th Congress of the European Society of Biomechanics, ESB 2025. Tzanetis, P., ten Klooster, L., Wolterink, J. M. & Verdonschot, N. J. J.Assessing the accuracy of ligament attachment sites for improved slope-correcting high tibial osteotomy planning in ACL-deficient patients using personalized musculoskeletal models (2025)[Contribution to conference › Poster] 10th Dutch Biomedical Engineering Conference, BME 2025. de Wilde, M., Veerman, Q., Tzanetis, P., Los, M. & Verdonschot, N. J. J.Comparative evaluation of sparse and minimal data point cloud registration: A study on Tibiofemoral Bones (2025)Journal of computational science, 84. Article 102463. Christie, D. A., Fluit, R., Durandau, G., Sartori, M. & Verdonschot, N.https://doi.org/10.1016/j.jocs.2024.102463Deviating from mechanical alignment in total knee arthroplastyinterchangeable targets?: are osteophyte-free knee kinematic and ligament strain restoration (2025)[Contribution to conference › Abstract] 36th International Society for Technology in Arthroplasty (ISTA) Annual Congress 2025. Tzanetis, P. & Verdonschot, N. J. J.

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University of Twente

Horst Complex (building no. 20), room W101
De Horst 2
7522 LW Enschede
Netherlands

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