prof.dr.ir. N.J.J. Verdonschot (Nico)

Scientific Director of the Technical Medical Centre

About Me

In 1988 I did my master thesis in Nijmegen at the Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at the Radboudumc Institute for Health Sciences (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (see www.erc-biomechtools.eu).

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Currently, I am the Scientific Director of the Technical Medical Centre. 

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling


Engineering & Materials Science
Medicine & Life Sciences
Biomechanical Phenomena
Bone And Bones
Knee Replacement Arthroplasties


Van Keulen, L. Z. , Hoogeslag, R. A. G., Brouwer, R. W., Huis In ’t Veld, R. , & Verdonschot, N. (2022). The importance of continuous remnant preservation in anterior cruciate ligament reconstruction. Knee surgery, sports traumatology, arthroscopy, 30, 1818-1827. https://doi.org/10.1007/s00167-021-06746-x
Tzanetis, P., de Souza, K., Robertson, S. , Fluit, R. , Koopman, H. F. J. M. , & Verdonschot, N. J. J. (Accepted/In press). Personalized musculoskeletal modeling of premorbid knees towards an optimally planned total knee arthroplasty. Abstract from 9th Dutch Bio-Medical Engineering Conference POSTPONED, Egmond aan Zee, Netherlands.
van Sambeeck, J. D. P. , Verdonschot, N., van Kampen, A., & van de Groes, S. A. W. (2021). Age at surgery is correlated with pain scores following trochlear osteotomy in lateral patellar instability: a cross-sectional study of 113 cases. Journal of orthopaedic surgery and research, 16(1), [337]. https://doi.org/10.1186/s13018-021-02485-4
Sánchez, E., Schilling, C., Grupp, T. M., Giurea, A., Wyers, C., van den Bergh, J. , Verdonschot, N., & Janssen, D. (2021). The effect of different interference fits on the primary fixation of a cementless femoral component during experimental testing. Journal of the mechanical behavior of biomedical materials, 113, [104189]. https://doi.org/10.1016/j.jmbbm.2020.104189
Anijs, T., Eemers, S., Minoda, Y., Wolfson, D. , Verdonschot, N., & Janssen, D. (2021). Computational tibial bone remodeling over a population after total knee arthroplasty: A comparative study. Journal of Biomedical Materials Research. Part B: Applied Biomaterials. https://doi.org/10.1002/jbm.b.34957
Ataei, A., Eggermont, F., Baars, M., Van Der Linden, Y., De Rooy, J. , Verdonschot, N., & Tanck, E. (2021). Evaluation of inter- and intra-operator reliability of manual segmentation of femoral metastatic lesions. International journal of computer assisted radiology and surgery, 16(10), 1841-1849. https://doi.org/10.1007/s11548-021-02450-w
Sánchez, E., Schilling, C., Grupp, T. M., Giurea, A. , Verdonschot, N., & Janssen, D. (2021). No effect in primary stability after increasing interference fit in cementless TKA tibial components. Journal of the mechanical behavior of biomedical materials, 118, [104435]. https://doi.org/10.1016/j.jmbbm.2021.104435
Soltanihafshejani, N., Bitter, T., Janssen, D. , & Verdonschot, N. (2021). Development of a crushable foam model for human trabecular bone. Medical engineering & physics, 96, 53-63. https://doi.org/10.1016/j.medengphy.2021.08.009

UT Research Information System

Courses Academic Year  2021/2022

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses Academic Year  2020/2021

Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Technohal (building no. 18), room 2103
Hallenweg 5
7522NH  Enschede
The Netherlands

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University of Twente
Faculty of Engineering Technology
Technohal (building no. 18), room 2103
Hallenweg 5
7522NH  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Technohal  2103
P.O. Box 217
7500 AE Enschede
The Netherlands

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