Horst Complex

prof.dr.ir. N.J.J. Verdonschot (Nico)

Professor Implant Biomechanics
ET-BE-BDDP
Horst Complex W101
n.verdonschot@utwente.nl
+31534896472
Business card

In 1988 I did my master thesis in Nijmegen at theĀ Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at theĀ Radboudumc Institute for Health SciencesĀ (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (www.tlemsafe.eu/).

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (seeĀ www.erc-biomechtools.eu).

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling

Expertise

  • Medicine and Dentistry

    • Total Knee Arthroplasty
    • Bone
    • Implant
    • Patient
    • Knee
    • Element
    • Magnetic Resonance Imaging
    • Measurement

Organisations

Ancillary activities

  • Invibio and Exactechadvise
  • Atro Medical1

Publications

2024

Prediction of micro-scale bone adaptation of human trabecular bone under different implanted conditions (2024)Journal of the mechanical behavior of biomedical materials, 160. Article 106747. Rana, M., Karmakar, S. K., Verdonschot, N. & Roychowdhury, A.https://doi.org/10.1016/j.jmbbm.2024.106747The influence of prosthetic suspension on gait and cortical modulations is persons with a transfemoral amputation: socket-suspended versus bone-anchored prosthesis (2024)Journal of neuroengineering and rehabilitation, 21(1). Article 35. Kooiman, V., van der Cruijsen, J., Leijendekkers, R., Verdonschot, N., Solis-Escalante, T. & Weerdesteyn, V.https://doi.org/10.1186/s12984-024-01331-ySIRC-UNet: Improving Bone Tracking Precision of A-mode Ultrasound by Decoding Hierarchical Resolution Features (2024)IEEE sensors journal, 24(22), 38174-38184. Lan, B., Abayazid, M., Verdonschot, N., Stramigioli, S. & Niu, K.https://doi.org/10.1109/JSEN.2024.3459657ISTA Award 2023: Toward functional reconstruction of the pre-diseased state in total knee arthroplasty (2024)The Bone & joint journal, 106-B(11), 1231 - 1239. Tzanetis, P., Fluit, R., de Souza, K., Robertson, S., Koopman, H. F. J. M. & Verdonschot, N. J. J.https://doi.org/10.1302/0301-620X.106B11.BJJ-2023-1357.R1High failure rate but promising clinical performance after implantation of a flexible medial meniscus prosthesis at 1ā€year followā€up (2024)Knee surgery, sports traumatology, arthroscopy (E-pub ahead of print/First online). van Minnen, B. S., Heesterbeek, P. J. C., Defoort, K. C., Emans, P. J., van Arkel, E. R. A., Struik, T., Jutten, L. M., Susan, S., van de Groes, S. A. W., Verdonschot, N. & van Tienen, T. G.https://doi.org/10.1002/ksa.12454Numerical study of osteophyte effects on preoperative knee functionality in patients undergoing total knee arthroplasty (2024)Journal of orthopaedic research, 42(9), 1943-1954. Tzanetis, P., de Souza, K., Robertson, S., Fluit, R., Koopman, H. F. J. M. & Verdonschot, N. J. J.https://doi.org/10.1002/jor.25850Knee Cartilage Estimation Based on Knee Bone Geometry Using Posterior Shape Model (2024)IEEE sensors journal, 24(19), 30600-30607. Chen, H., Tan, T., Kang, Y., Sun, Y., Xie, H., Wang, X. & Verdonschot, N.https://doi.org/10.1109/JSEN.2024.3443994The primary stability of a cementless PEEK femoral component is sensitive to BMI: A population-based FE study (2024)Journal of biomechanics, 168. Article 112061. Post, C. E., Bitter, T., Briscoe, A., Fluit, R., Verdonschot, N. & Janssen, D.https://doi.org/10.1016/j.jbiomech.2024.112061A Method to Track 3D Knee Kinematics by Multi-Channel 3D-Tracked A-Mode Ultrasound (2024)Sensors (Switzerland), 24(8). Article 2439. Niu, K., Sluiter, V., Lan, B., Homminga, J., Sprengers, A. & Verdonschot, N.https://doi.org/10.3390/s24082439Quantification of long-term nonlinear stress relaxation of bovine trabecular bone (2024)Journal of the mechanical behavior of biomedical materials, 152, 106434. Article 106434. Gersie, T., Bitter, T., Wolfson, D., Freeman, R., Verdonschot, N. & Janssen, D.https://doi.org/10.1016/j.jmbbm.2024.106434

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University of Twente

Horst Complex (building no. 20), room W101
De Horst 2
7522 LW Enschede
Netherlands

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