In 1988 I did my master thesis in Nijmegen at the Orthopaedic Research Laboratory(ORL). After my graduation mid- 1989 I stayed at the ORL as Junior Researcher and performed various kinds of projects focusing on testing of orthopaedic implants. Most projects were funded by the Orthopaedic Industry which gradually led to an extensive network of R&D departments of small to large international orthopaedic companies. The publications of these projects resulted in my Ph.D. degree in 1995. Subsequently I was promoted to Assistant Professor and was appointed to be Director of Pre-clinical testing of joint implants. In 2003 I was further promoted to Associate Professor. Since February 2014 I am a full Professor at the Radboudumc Institute for Health Sciences (RIHS), my theme is 'Reconstructive and regenerative medicine'.

My research interests are focused on orthopaedic-biomechanical problems of the lower extremity. Our group utilizes computer modelling techniques in combination with cadaveric testing, animal research and clinical studies in order to optimize diagnostic and evaluation tools for orthopaedic patients. We work with researchers and orthopaedic companies to optimize the functionality and longevity of orthopaedic implants such as knee and hip prostheses. Furthermore, we focus on the calculation of bone strength for patients that have osteoporosis or metastatic lesions.

Since October 2007 I have a part-time appointment (1 day per week) as Professor in Implant Biomechanics at the University of Twente (dept. Biomechanical Engineering headed by Prof. Bart Koopman), where I am setting up a research line related to biomechanics of the Musculo-Skeletal system, see TLEMsafe (

In December 2012 I was awarded a 'European Research Council - Advanced Grant' for follow up research. In Nijmegen we are currently expanding our modelling efforts to generate patient specific models and feed these models with innovative dynamic imaging techniques (see

In 2016 I was appointed as a visiting professor at the Politecnico di Milano (Italy)

In 2018 I received an Honorary Doctorate of Aalborg University (Denmark)

Fields of interest

  • implants, biomechanics,
  • finite element models,
  • musculoskeletal modelling


  • Medicine and Dentistry

    • Bone
    • Total Knee Arthroplasty
    • Patient
    • Knee
    • Implant
    • Element
    • Magnetic Resonance Imaging
    • Measurement


Ancillary activities

  • Invibio and Exactechadvise
  • Atro Medical1


Testing and evaluation of lower limb prosthesis prototypes in people with a transfemoral amputation: a scoping review on research protocolsJournal of neuroengineering and rehabilitation, 20(1), Article 1. Kooiman, V. G. M., van Staveren, E. S., Leijendekkers, R. A., Buurke, J. H., Verdonschot, N., Prinsen, E. C. & Weerdesteyn, V. in modeling and simulation of the knee: Academic, industry, and regulatory perspectivesJournal of orthopaedic research, 41(12), 2569-2578. Imhauser, C. W., Baumann, A. P., Liu, X., Bischoff, J. E., Verdonschot, N., Fregly, B. J., Elmasry, S. S., Abdollahi, N. N., Hume, D. R., Rooks, N. B., Schneider, M. T. Y., Zaylor, W., Besier, T. F., Halloran, J. P., Shelburne, K. B. & Erdemir, A. sensitivity of the stiffness and thickness of a titanium inlay in a cementless PEEK femoral component to the micromotions and bone strain energy densityMedical Engineering and Physics, 122, Article 104072. Post, C. E., Bitter, T., Briscoe, A., Verdonschot, N. & Janssen, D. Surgery and Implant Modifications Been Associated With Reduction in Soft Tissue Complications in Transfemoral Bone-anchored Prostheses?Clinical orthopaedics and related research, 481(7), 1373-1384. Atallah, R., Reetz, D., Verdonschot, N., De Kleuver, M., Frölke, J. P. M. & Leijendekkers, R. A. consumption and gait dynamics in transfemoral bone-anchored prosthesis users compared to socket-prosthesis users: A cross-sectional studyGait and Posture, 103, 12-18. Kooiman, V., Haket, L., Verdonschot, N., Leijendekkers, R. & Weerdesteyn, V.

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University of Twente

Horst Complex (building no. 20), room W101
De Horst 2
7522 LW Enschede

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