I am co-founder and CEO of Phos4nova B.V.. I hold a PhD in nanochemistry and more than 15 years of experience in nanomedicine and imaging agent development. In the last 5 years I have, moreover, built a strong business development skills. Currently, I am about to complete executive MBA in business management at the University of Münster.
Expertise
Chemistry
- Nanoparticle
- Magnetic Resonance Imaging
- Polymer
- Particle Size
- Surface Property
- Silicon Dioxide
- Time
Material Science
- Particle
Organisations
Publications
2025
Mimicking Block Copolymer Self-Assembly with One-Pot Synthesized Polyphosphoester Gradient Copolymers (2025)Advanced functional materials. Article e26728 (E-pub ahead of print/First online). Azhdari, S., Rheinberger, T., Mansfeld, U., Post, Y., Linders, J., Koshkina, O., Gröschel, A. H. & Wurm, F. R.https://doi.org/10.1002/adfm.202526728The Environmental Impact of Medical Imaging Agents and the Roadmap to Sustainable Medical Imaging (2025)Advanced science, 12(9). Article 2404411. Pichler, V., Martinho, R. P., Temming, L., Segers, T., Wurm, F. R. & Koshkina, O.https://doi.org/10.1002/advs.202404411
2024
Super-resolution Optoacoustic Imaging of Cerebral Microcirculation with Indocyanine Green Microcapsules (2024)ACS photonics, 11(11), 4642-4647. Tang, L., Nozdriukhin, D., Özsoy, C., Chen, Y., Wrum, F. R., Koshkina, O., Razansky, D. & Deán-Ben, X. L.https://doi.org/10.1021/acsphotonics.4c01050Accelerated hydrolysis and degradation of polylactide nanocomposites using loaded silica nanocarriers (2024)Chemical Engineering Journal, 491. Article 151903. Zhu, X., Gojzewski, H., Koshkina, O. & Wurm, F. R.https://doi.org/10.1016/j.cej.2024.151903
2023
The internal structure of gadolinium and perfluorocarbon-loaded polymer nanoparticles affects 19F MRI relaxation times (2023)Nanoscale, 15(44), 18068-18079. Mali, A., Verbeelen, M., White, P. B., Staal, A. H. J., van Riessen, N. K., Cadiou, C., Chuburu, F., Koshkina, O. & Srinivas, M.https://doi.org/10.1039/d3nr04577cMake a break with polyphosphoesters: From sequence control to biodegradable polymers and biomedical materials (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Rheinberger, T.https://doi.org/10.3990/1.9789036557412Real-time 31P NMR reveals different gradient strengths in polyphosphoester copolymers as potential MRI-traceable nanomaterials (2023)Communications Chemistry, 6(1). Article 182. Rheinberger, T., Flögel, U., Koshkina, O. & Wurm, F. R.https://doi.org/10.1038/s42004-023-00954-xBiobased Agents for Single‐Particle Detection with Optoacoustics (2023)Small, 19(29). Article 2207199. Chen, Y., Nozdriukhin, D., Michel-Souzy, S., Padberg, C., Wurm, F. R., Razansky, D., Deán‐Ben, X. L. & Koshkina, O.https://doi.org/10.1002/smll.202207199Biodegradable polyphosphoester micelles act as both background-free 31P magnetic resonance imaging agents and drug nanocarriers (2023)Nature communications, 14(1). Article 4351. Koshkina, O., Rheinberger, T., Flocke, V., Windfelder, A., Bouvain, P., Hamelmann, N. M., Paulusse, J. M. J., Gojzewski, H., Flögel, U. & Wurm, F. R.https://doi.org/10.1038/s41467-023-40089-0Multibranched-Based Fluorinated Materials: Tailor-Made Design of 19F-MRI Probes (2023)Accounts of Materials Research, 4(1), 71-85. Bona, B. L., Koshkina, O., Chirizzi, C., Dichiarante, V., Metrangolo, P. & Baldelli Bombelli, F.https://doi.org/10.1021/accountsmr.2c00203
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