prof.dr. P.C.J.J. Passier (Robert)

Full Professor
TNW-BET-AST
Horst - Zuidhorst 123
robert.passier@utwente.nl
+31534895553
Business card

Expertise

  • Medicine and Dentistry

    • Cardiomyocyte
    • Pluripotent Stem Cell
    • Cells
    • Heart
    • Tissues
    • Disease
    • In Vitro
    • Differentiation

Organisations

Publications

2026

Development of advanced in vitro models of the human heart recapitulating pump function and cardiac conduction dynamics (2026)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Cano Jorge, M.https://doi.org/10.3990/1.9789036570183Cross-modal integration of metabolomics and cardiac functionality captures dynamic metabotoxic effects of doxorubicin in engineered heart tissues (2026)Stem cell reports, 21(1). Article 102725. Conte, F., Staykova, D. K., Cofiño-Fabres, C., Snippert, D., van Rooij, A., Lefeber, D. J. & Passier, R.https://doi.org/10.1016/j.stemcr.2025.102725Mini-hearts for disease modeling and drug testing – process optimization versus biological functionality (2026)Frontiers in bioengineering and biotechnology, 13. Article 1719533. Hecking, J., Cano-Jorge, M., Passier, R. & Rivera-Arbeláez, J. M.https://doi.org/10.3389/fbioe.2025.1719533

2025

Mapping cardiac drug transport: In vitro assessment of cardiac P-glycoprotein function with [18F]MC225 by using µ-engineered heart tissues (2025)European Heart Journal Open, 5(6). Article oeaf150. Liu, W., Dannenberg, M., Mossel, P., Cai, Z., Farinha Antunes, I., Sijbesma, J., Kwizera, C., Cao, L., van der Meer, A., Passier, R., Slart, R. H. J. A., Schwach, V. & Luurtsema, G.https://doi.org/10.1093/ehjopen/oeaf150In vitro approaches to mimic cardiac mechanical load dynamics for enhancing maturation and disease modelling (2025)Cardiovascular Research, 121(16), 2484-2502. Cano-Jorge, M., Gómez, S., Den Toonder, J., Wang, Y. & Passier, R.https://doi.org/10.1093/cvr/cvaf247Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues (2025)Frontiers in bioengineering and biotechnology, 13. Article 1686342.. Sterckel, S., Passier, R. & Rivera Arbelaez, J. M.https://doi.org/10.3389/fbioe.2025.1686342A human engineered mini-heart platform for mimicking ventricular pump function (2025)[Working paper › Preprint]. bioRxiv. Ribeiro, M. C., Cano-Jorge, M., ten Den, S., Snippert, D., Karperien, M., Kamperman, T., Lajoinie, G. P. R., Versluis, M. & Passier, R.https://doi.org/10.1101/2025.08.25.672056Translational insight into MASH: From mechanisms to medicine (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. ten Hove, M. M.https://doi.org/10.3990/1.9789036566315Blood-perfused vessels-on-chip for disease modelling and precision medicine (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Weener, H. J.https://doi.org/10.3990/1.9789036567107Retina-on-chip with local oxygen sensing (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Gensheimer, T.https://doi.org/10.3990/1.9789036567084

Research profiles

Address

University of Twente

Horst - Zuidhorst (building no. 28), room 123
De Horst 2
7522 LW Enschede
Netherlands

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