prof.dr. P.C.J.J. Passier (Robert)

Full Professor


Pluripotent Stem Cells
Cardiac Myocytes
Stem Cells
In Vitro Techniques
Cell Line
Transcription Factors
Blood Vessels
Embryonic Stem Cells


Recent Articles
Passier, R. (2017). Modelling and drug screening for cardiovascular disease. Acta physiologica, 219(S711), 7-7. [SO2-2]. DOI: 10.1111/apha.12866
Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., ... Denning, C. (2017). InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility. Journal of Pharmacological and Toxicological Methods, 88(2), 238-238. [0227]. DOI: 10.1016/j.vascn.2017.09.228
Rogers, M., Ridley, J., El-Haou, S., Williams, S., Webdale, L., Sutton, K., ... Passier, R. (2017). Human Ventricular Stem Cell Cardiomyocytes: Validating In Vitro Assays and Screening Platforms for Pro-arrhythmia Risk Prediction. Journal of Pharmacological and Toxicological Methods, 88(2), 241-241. [0237]. DOI: 10.1016/j.vascn.2017.09.238
Van Eldik, W., Den Adel, B., Monshouwer-Kloots, J. J., Salvatori, D., Maas, S., Van Der Made, I., ... Beqqali, A. (2017). Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart. PLoS ONE, 12(12), [e0189139]. DOI: 10.1371/journal.pone.0189139
Guadix, J. A., Orlova, V. V., Giacomelli, E., Bellin, M., Ribeiro, M. C., Mummery, C. L., ... Passier, R. (2017). Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells. Stem cell reports, 9(6), 1754-1764. DOI: 10.1016/j.stemcr.2017.10.023
Schwach, V., Verkerk, A. O., Mol, M., Monshouwer-Kloots, J. J., Devalla, H. D., Orlova, V. V., ... Passier, R. (2017). A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes. Stem cell reports, 9(6), 1765-1779. DOI: 10.1016/j.stemcr.2017.10.024
Mummery, C., Birket, M. J., Meer, B., Ribeiro, M., Passier, R., Bellin, M., ... Tertoolen, L. (2016). Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models. Human Gene Therapy, 27(11), A11-A11. [INV38]. DOI: 10.1089/hum.2016.29035.abstracts
van Meer, B., Catarino Ribeiro, M., Tertoolen, L., Birket, M. J., Passier, R., & Mummery, C. (2016). Organ-on-Chip: A synthetic mimic for human myocardium. Journal of Pharmacological and Toxicological Methods, 81, 388-388. [0176]. DOI: 10.1016/j.vascn.2016.02.173

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Contact Details

Visiting Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst (building no. 28), room 126
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Science and Technology
Horst - Zuidhorst  126
P.O. Box 217
7500 AE Enschede
The Netherlands