prof.dr. P.C.J.J. Passier (Robert)

Medicine & Life Sciences

# Cardiac Myocytes
# Heart
# Human Embryonic Stem Cells
# Microfluidics
# Pluripotent Stem Cells

Engineering & Materials Science

# Cell Culture
# Microfluidics
# Stem Cells

Faculty of Science and Technology (TNW), Applied Stem Cell Technologies (AST)

Cofiño-Fabres, C., Boonen, T., Rivera-Arbeláez, J. M., Rijpkema, M., Blauw, L., Rensen, P. C. N. , Schwach, V. , Ribeiro, M. C. , & Passier, R. (2024). Micro-Engineered Heart Tissues On-Chip with Heterotypic Cell Composition Display Self-Organization and Improved Cardiac Function. Advanced healthcare materials, Article 2303664. Advance online publication. https://doi.org/10.1002/adhm.202303664

Schwach, V. , Slaats, R. H., Cofiño-Fabres, C., ten Den, S. A., Rivera-Arbeláez, J. M., Dannenberg, M., van Boheemen, C. , Ribeiro, M., van der Zanden, S. Y., Nollet, E. E., van der Velden, J., Neefjes, J. , Cao, L. , & Passier, R. (2024). A safety screening platform for individualized cardiotoxicity assessment. iScience, 27(3), Article 109139. https://doi.org/10.1016/j.isci.2024.109139

Jongsma, S. , Schwach, V., Den, S. A. T. , Passier, R., Verbeek, F. J. , & Cao, L. (2023). Segmentation of NKX2.5 Signal in Human Pluripotent Stem Cell-Derived Cardiomyocytes. In C. Anutariya, & M. M. Bonsangue (Eds.), Data Science and Artificial Intelligence - 1st International Conference, DSAI 2023, Proceedings (pp. 170-184). (Communications in Computer and Information Science; Vol. 1942 CCIS). Springer. https://doi.org/10.1007/978-981-99-7969-1_13

Cofiño-Fabres, C. , Passier, R. , & Schwach, V. (2023). Towards Improved Human In Vitro Models for Cardiac Arrhythmia: Disease Mechanisms, Treatment, and Models of Atrial Fibrillation. Biomedicines, 11(9), Article 2355. https://doi.org/10.3390/biomedicines11092355

Conte, F., Sam, J.-E., Lefeber, D. J. , & Passier, R. (2023). Metabolic Cardiomyopathies and Cardiac Defects in Inherited Disorders of Carbohydrate Metabolism: A Systematic Review. International journal of molecular sciences, 24(10), Article 8632. https://doi.org/10.3390/ijms24108632

van Loo, S. R., ten Den, S. A. , Araújo-Gomes, N., de Jong, V., Snabel, R. , Schot, M. R., Rivera Arbelaez, J. M., Veenstra, G. J. , Passier, R. , Kamperman, T. , & Leijten, J. (2023). Mass production of lumenogenic human embryoid bodies and functional cardiospheres using in-air-generated microcapsules. Nature communications, 14, Article 6685. https://doi.org/10.1038/s41467-023-42297-0

Cofino Fabres, C. (2023). Advancements in molecular and bioengineering techniques for driving maturation of human pluripotent stem cell-derived cardiac three-dimensional models. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036558228

Mostert, D., Jorba, I., Groenen, B. G. W. , Passier, R., Goumans, M. J. T. H., van Boxtel, H. A., Kurniawan, N. A., Bouten, C. V. C., & Klouda, L. (2023). Methacrylated human recombinant collagen peptide as a hydrogel for manipulating and monitoring stiffness-related cardiac cell behavior. iScience, 26(4), Article 106423. https://doi.org/10.1016/j.isci.2023.106423

Rivera-Arbeláez, J. M., Keekstra, D., Cofiño-Fabres, C., Boonen, T., Dostanic, M., ten Den, S. A., Vermeul, K., Mastrangeli, M. , van den Berg, A. , Segerink, L. I., Ribeiro, M. C. , Strisciuglio, N. , & Passier, R. (2023). Automated assessment of human engineered heart tissues using deep learning and template matching for segmentation and tracking. Bioengineering and Translational Medicine, 8(3), Article e10513. https://doi.org/10.1002/btm2.10513

Cao, L., Schoenmaker, L., Ten Den, S. A. , Passier, R. , Schwach, V., & Verbeek, F. J. (2023). Automated Sarcomere Structure Analysis for Studying Cardiotoxicity in Human Pluripotent Stem Cell-Derived Cardiomyocytes. Microscopy and microanalysis, 29(1), 254-264. https://doi.org/10.1093/micmic/ozac016

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