prof.dr. P.C.J.J. Passier (Robert)

Medicine & Life Sciences

# Cardiac Myocytes
# Heart
# Human Embryonic Stem Cells
# Microfluidics
# Pluripotent Stem Cells

Engineering & Materials Science

# Cell Culture
# Microfluidics
# Stem Cells

Faculty of Science and Technology (TNW), Applied Stem Cell Technology (AST)

Harlaar, N., Dekker, S. O., Zhang, J., Snabel, R. R., Veldkamp, M. W., Verkerk, A. O. , Fabres, C. C. , Schwach, V., Lerink, L. J. S., Rivaud, M. R., Mulder, A. A., Corver, W. E., Goumans, M. J. T. H., Dobrev, D., Klautz, R. J. M., Schalij, M. J., Veenstra, G. J. C. , Passier, R., van Brakel, T. J., ... de Vries, A. A. F. (2022). Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation. Nature Biomedical Engineering, 6, 389-402. https://doi.org/10.1038/s41551-021-00827-5

Ribeiro, M. C. , Rivera-Arbelaez, J. M. , Cofino-Fabres, C. , Schwach, V. , Slaats, R. H. , ten Den, S. A. , Vermeul, K. , van den Berg, A., Perez-Pomares, J. M. , Segerink, L. I., Guadix, J. A. , & Passier, R. (2022). A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues. Journal of Personalized Medicine, 12(2), [214]. https://doi.org/10.3390/jpm12020214

Mostert, D., Masdeu, I. J. , Passier, R. P. C. J. J., Kurniawan, N. A., & Bouten, C. V. C. (2022). Mechanical constraint model to understand remodeling in beating cardiac microtissues. Biophysical journal, 121(3), 263A-264A. https://doi.org/10.1016/j.bpj.2021.11.1413

Vivas, A. , van den Berg, A. , Passier, R. , Odijk, M. , & van der Meer, A. D. (2022). Fluidic circuit board with modular sensor and valves enables stand-alone, tubeless microfluidic flow control in organs-on-chips. Lab on a chip, 22(6), 1231-1243. https://doi.org/10.1039/d1lc00999k

Vivas, A., IJspeert, C., Pan, J. Y. , Vermeul, K. , van den Berg, A. , Passier, R., Keller, S. S. , & van der Meer, A. D. (2022). Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co-Culture. Advanced Materials Technologies, 7(7), [2101355]. https://doi.org/10.1002/admt.202101355

van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. In Proceedings of the 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 (pp. 495-496)

van Dorp, T. , Paggi, C. A. , Slaats, R. H. , Schwach, V. , le Gac, S. , Passier, R. , & Karperien, M. (2021). Cyclic exposure to compressive forces increases the differentiation efficiency of hipscs towards chondrocytes in a cartilage-on-chip platform. Poster session presented at 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2021, Palm Springs, California, United States.

Vivas, A. , Berg, A. V. D. , Passier, R. , Odijk, M. , & Meer, A. D. V. D. (2021). Fluidic Circuit Board with Modular Sensor and Valves Enables Stand-Alone, Tubeless Microfluidic Flow Control in Organs-on-Chips. bioRxiv. https://doi.org/10.1101/2021.11.24.469685

Slaats, R. H. (2021). Modelling the human heart: Human stem cell-based models lead the way in physiological, pathological, and toxicological research. University of Twente. https://doi.org/10.3990/1.9789036552318

Arik, Y. B. , De sa Vivas, A., Laarveld, D., Van Laar, N., Gemser, J., Visscher, T. , van den Berg, A. , Passier, R. , & van der Meer, A. D. (2021). Collagen I based enzymatically degradable membranes for organ-on-a-chip barrier models. ACS Biomaterials Science and Engineering, 7(7), 2998-3005. https://doi.org/10.1021/acsbiomaterials.0c00297

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