prof.dr.ir. S. Le Gac (Severine)

Séverine Le Gac received her Engineer degree in chemistry (specialization biology) from the ESPCI (Paris, France) and her DEA (MSc equivalent; interface biology/chemistry) from the MNHN (Paris, France) in 2000. In 2004, she obtained her PhD degree cum laude in life sciences from the University of Lille (Lille, France) for the development of microfluidic systems for proteomic analysis by mass spectrometry. For this work she conducted in the group of Dr. Rolando, she was attributed the PhD prize of the French Society for Mass Spectrometry in 2005. After a 2-months stay in the lab of Prof. Yoshinobu Baba in Japan, she started as a post-doctoral fellow at the University of Twente, at the MESA+ Institute for Nanotechnology and the BIOS, Lab-on-a-Chip Group under the supervision of Prof. Albert van den Berg. After a 3-year post-doctoral stay, she was offered a tenure-track position (assistant professor) in the same group and the same institute. In 2012, she was appointed Program Director for the topic “Innovative Nanotechnology for Medicine” at the MESA+ Institute for Nanotechnology and in 2013, she obtained tenure.

Currently, Dr. Le Gac is a Full Professor at the University of Twente (The Netherlands) and she is leading a team called “Applied Microfluidics for BioEngineering Research – AMBER” which is part of the MESA+ Institute for Nanotechnology and the TechMed Institute. She is Associate Editor of the peer-reviewed journal Lab on a Chip (RSC) and president of the Director Board of the CBMS Society (Chemical and Biological Microsystems Society). She was chairing MicroTAS, 2020 with Prof. Hang Lu (GeorgiaTech).

Her research interests focus on the use of microfluidic devices for biological and medical applications, for biomarker analysis and the development of organ-on-a-chip platforms with a particular focus on disease modeling (cancer, fibrotic diseases) and the field of medically assisted reproduction.

Expertise

• Engineering

  • Microfluidic Device
  • Microfluidic Platform

• Material Science

  • Polydimethylsiloxane
  • Cell Membrane
  • Lipid Bilayer
  • Tumor
  • Nanoparticle
  • Raman Spectroscopy

Organisations

Ancillary activities

• Royal Society of ChemistryAssociate Editor for the Lab on a Chip journal
• Swedish Research CouncilPanel Chair

Publications

Research profiles

Affiliated study programs

Courses academic year 2026/2027

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2025/2026

Courses academic year 2024/2025

Address

University of Twente

Horst Complex (building no. 20), room ZH135
De Horst 2
7522 LW Enschede
Netherlands

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Organisations