Srirang Manohar is Professor and Chair, Multi-Modality Medical Imaging (M3I), a new research group. He has pioneered research into photoacoustic imaging of breast cancer. He also investigates the feasibility of the method hybrid with ultrasound imaging in image guidance of Radiofrequency Ablation, imaging ulcers in the diabetic foot, inflammation in joints in rheumatoid arthritis, and imaging of thyroid nodules. Prof. Manohar’s research spans technology development to early clinical assessment. The intended applications of the technologies span the range of ex vivo tissue imaging, minimally-invasive imaging to non-invasive. He has also done investigations into synthesis and characterization of gold nanoparticles, and in vitro and in vivo application of these and iron oxide nanoparticles in the context of providing contrast for photoacoustics.

Prof. Manohar is the Chair of the Biomedical Imaging & Sensing Department. He is also co-coordinator of the Domain Imaging & Diagnostics at the University of Twente. He has coordinated the H2020 project, PAMMOTH running from 2017-2021. He is also coordinator of the Dutch-India consortium Imaging Needles. Prof. Manohar is in the Editorial Board of the journal Elsevier Photoacoustics, and has co-edited two Special Issues. He is member of the Organizing Committee for the conference “Photons plus Ultrasound: Imaging and Sensing held annually under auspices of SPIE (Photonics West, San Francisco, USA). He is also member of the Program Committee for the conference Opto-Acoustic Methods & Applications, European Conferences on Biomedical Optics (ECBO), Munich, Germany.

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Expertise

  • Nursing and Health Professions

    • Photoacoustics
    • Imaging
  • Medicine and Dentistry

    • Photoacoustic Imaging
    • Breast
    • Photoacoustic Tomography
    • Breast Imaging
  • Physics

    • Ultrasound
    • Tomography

Organisations

Biomedical imaging specifically photoacoustic imaging and ultrasound imaging for non-invasive and minimally-invasive detection, diagnosis and therapy monitoring of various pathologies including breast cancer, rheumatoid arthritis, thyroid and the diabetic foot.

Publications

2025

Radiofrequency Ablation for Thyroid Nodules (RATED Study): Analysis of a Learning Curve and Predictors of Success (2025)Journal of clinical endocrinology and metabolism, 110(11), 3201-3209. Article dgaf058. van der Meeren, M. M. D., Boers, T., de Graaf, P., Duvivier, K. M., Dreijerink, K. M. A., Deden, L. N., Veendrick, P., Cernohorsky, P., Joosten, F. B. M., Savelberg, A. B. M. C., Braak, S. J., Roerink, S. H. P. P., Versluis, M., Manohar, S. & Oyen, W. J. G.https://doi.org/10.1210/clinem/dgaf058Artifacts in photoacoustic imaging: Origins and mitigations (2025)Photoacoustics, 45. Article 100745. Rietberg, M. T., Gröhl, J., Else, T. R., Bohndiek, S. E., Manohar, S. & Cox, B. T.https://doi.org/10.1016/j.pacs.2025.100745Feasibility of Laser Speckle-Based Perfusion Imaging in an Ex-Vivo Liver Model (2025)IEEE journal of translational engineering in health and medicine, 13, 437-449. Chizari, A., van der Hoek, J. L., Rook, A. R. D., Krommendijk, M. E., Snoeijink, T. J., Visser, A., Knop, T., Arens, J., Manohar, S., Steenbergen, W. & Groot Jebbink, E.https://doi.org/10.1109/JTEHM.2025.3602158Baseline PSMA PET/CT parameters predict overall survival and treatment response in metastatic castration-resistant prostate cancer patients (2025)European radiology, 35(7), 4223-4232. Article 4254. Kleiburg, F., de Geus-Oei, L. F., Spijkerman, R., Noortman, W. A., van Velden, F. H. P., Manohar, S., Smit, F., Toonen, F. A. J., Luelmo, S. A. C., van der Hulle, T. & Heijmen, L.https://doi.org/10.1007/s00330-025-11360-3Ultrasound contrast microbubbles to predict the microsphere distribution during transarterial radioembolization with holmium microspheres, an in vitro proof of concept study (2025)Drug Delivery, 32(1). Article 2505007 (E-pub ahead of print/First online). van der Hoek, J. L., Snoeijink, T. J., Mirgolbabaee, H., Kunst, R., Versluis, M., Arens, J., Manohar, S. & Groot Jebbink, E.https://doi.org/10.1080/10717544.2025.2505007Dataset for "In-vivo absorption and reduced scattering spectra across five body locations on ten subjects using time-domain diffuse optics" (2025)[Dataset Types › Dataset]. Zenodo. Bargigia, I., Karremans, S., Damagatla, V., Bossi, A., Manohar, S., Taroni, P., Cubeddu, R. & Pifferi, A.https://doi.org/10.5281/zenodo.15178164Artifacts in photoacoustic imaging (2025)In Photons Plus Ultrasound: Imaging and Sensing 2025. Article 1331912 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 13319). SPIE. Rietberg, M. T., Gröhl, J., Else, T. R., Bohndiek, S. E., Manohar, S. & Cox, B. T.https://doi.org/10.1117/12.3043855Development of a cerebral CT perfusion phantom: A structured approach (2025)Physica medica, 131. Article 104944. Goris, L., Zaid Al-Kaylani, A. H. A., Schuurmann, R. C. L., Greuter, M., Bokkers, R. & Manohar, S.https://doi.org/10.1016/j.ejmp.2025.104944The LiverTwin: a novel ex-vivo experimental platform for multi-modal image-guided liver cancer treatment studies (2025)[Contribution to conference › Poster] 10th Dutch Biomedical Engineering Conference, BME 2025. van der Hoek, J. L., Krommendijk, M. E., Snoeijink, T. J., Chizari, A., Rook, A., De Bree, K., Greve, J. G. M., Liefers, H. R., Steenbergen, W., Versluis, M., Arens, J., Manohar, S. & Groot Jebbink, E.Image Analysis of Patient Data from the Hybrid Photoacoustic-Ultrasound Tomography System PAM3 (2025)In Photons Plus Ultrasound: Imaging and Sensing 2025. Article 1331902 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 13319). SPIE. De Santi, B., Lucka, F., Bulthuis, R. F. G., Veltman, J., van der Schaaf, M., Messal, H., Brinkhuis, M., Cox, B. & Manohar, S.https://doi.org/10.1117/12.3043362

Research profiles

Prizes and Awards

[1]    Best project Module in TNW 2015-2016 – Microscopisch detective van kanker – elected by students BMT. with Dr. J. Alers module coordinator

[2]    Decentrale Onderwijsprijs 2015 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[3]    Decentrale Onderwijsprijs 2014 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[4]    TNW (Science & Technology) Education Award 2012 for excellence in education in the Biomedical Technology (BMT) Education stream.

[5]    Decentrale Onderwijsprijs 2010 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

 

LIGHT BOARD PROJECT

Developed a DIY Lightboard to give online classes during the COVID-19 pandemic.

Affiliated study programs

Courses academic year 2025/2026

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2024/2025

In the press

1) Volkskrant 9 December 2022 "Kan de screening van borstkanker nog beter? Vijf methoden waaraan Nederlandse onderzoekers werken".
2) National Televison (Atlas NTR NPO2) 19 October 2022 "Kun je pijnloos testen op borstkanker?"
3) Health Management (2016) "Dream Imager for Breast Cancer Diagnosis"
4) Volkskrant 4 oktober 2014 "Redt preventieve screening op borstkanker levens?"
5) NRC 22 december 2012 "Batsheba had toch geen borstkanker"

Address

University of Twente

Technohal (building no. 18), room 2380
Hallenweg 5
7522 NH Enschede
Netherlands

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