Srirang Manohar is Professor and Chair, Multi-Modality Medical Imaging (M3I), a new research group. He has pioneered research into photoacoustic imaging of breast cancer. He also investigates the feasibility of the method hybrid with ultrasound imaging in image guidance of Radiofrequency Ablation, imaging ulcers in the diabetic foot, inflammation in joints in rheumatoid arthritis, and imaging of thyroid nodules. Prof. Manohar’s research spans technology development to early clinical assessment. The intended applications of the technologies span the range of ex vivo tissue imaging, minimally-invasive imaging to non-invasive. He has also done investigations into synthesis and characterization of gold nanoparticles, and in vitro and in vivo application of these and iron oxide nanoparticles in the context of providing contrast for photoacoustics.

Prof. Manohar is the coordinator of the Domain Imaging & Diagnostics at the University of Twente. He also coordinates the H2020 project, PAMMOTH running from 2017-2021. He is also coordinator of the Dutch-India consortium Imaging Needles. He is member of the Organizing Committee for the conference “Photons plus Ultrasound: Imaging and Sensing held annually under auspices of SPIE (Photonics West, San Francisco, USA). He is also member of the Program Committee for the conference Opto-Acoustic Methods & Applications, European Conferences on Biomedical Optics (ECBO), Munich, Germany.

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Expertise

  • Nursing and Health Professions

    • Photoacoustics
    • Imaging
  • Physics

    • Ultrasound
    • Tomography
  • Medicine and Dentistry

    • Photoacoustic Imaging
    • Breast
    • Photoacoustic Tomography
    • Breast Imaging

Organisations

Biomedical imaging specifically photoacoustic imaging and ultrasound imaging for non-invasive and minimally-invasive detection, diagnosis and therapy monitoring of various pathologies including breast cancer, rheumatoid arthritis, thyroid and the diabetic foot.

Publications

2024

3D ultrasound guidance for radiofrequency ablation in an anthropomorphic thyroid nodule phantom (2024)European radiology experimental, 8(1). Article 115. Boers, T., Braak, S. J., Brink, W. M., Versluis, M. & Manohar, S.https://doi.org/10.1186/s41747-024-00513-6Super phantoms: advanced models for testing medical imaging technologies (2024)Communications Engineering, 3(1). Article 73. Manohar, S., Sechopoulos, I., Anastasio, M. A., Maier-Hein, L. & Gupta, R.https://doi.org/10.1038/s44172-024-00218-zEx-Vivo Human-Sized Organ Machine Perfusion: A Systematic Review on the Added Value of Medical Imaging for Organ Condition Assessment (2024)Transplant international, 37. Article 12827. van der Hoek, J. L., Krommendijk, M. E., Manohar, S., Arens, J. & Groot Jebbink, E.https://doi.org/10.3389/ti.2024.12827Ex-Vivo Human-Sized Organ Machine Perfusion: A Systematic Review on the Added Value of Medical Imaging for Organ Condition Assessment (2024)Transplant international, 37. Article 12827. Van Der Hoek, J. L., Krommendijk, M. E., Manohar, S., Arens, J. & Groot Jebbink, E.https://doi.org/10.3389/ti.2024.12827Tutorial on phantoms for photoacoustic imaging applications (2024)Journal of biomedical optics, 29(8). Article 080801. Hacker, L., Joseph, J., Lilaj, L., Manohar, S., Ivory, A. M., Tao, R. & Bohndiek, S. E.https://doi.org/10.1117/1.JBO.29.8.080801Enter the matrix: On how to improve thyroid nodule management using 3D ultrasound (2024)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Boers, T.https://doi.org/10.3990/1.9789036560696In-line spectroscopy for the quantification of iodine in a breast perfusion phantom for dynamic contrast-enhanced dedicated breast CT imaging validation (2024)In Medical Imaging 2024: Physics of Medical Imaging. Article 1292547. Goris, L., Mikerov, M., Manohar, S. & Sechopoulos, I.https://doi.org/10.1117/12.3006763Using denoising diffusion probabilistic models to enhance quality of limited-view photoacoustic tomography (2024)In Photons Plus Ultrasound: Imaging and Sensing 2024. Article 1284213 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 12842). SPIE. De Santi, B., Awasthi, N. & Manohar, S.https://doi.org/10.1117/12.3001616An anthropomorphic thyroid phantom for ultrasound-guided radiofrequency ablation of nodules (2024)Medical physics, 51(2), 826-838. Boers, T., Brink, W., Bianchi, L., Saccomandi, P., van Hespen, J., Wennemars, G., Braak, S., Versluis, M. & Manohar, S.https://doi.org/10.1002/mp.16906Automated three-dimensional image registration for longitudinal photoacoustic imaging (2024)Journal of biomedical optics, 29(S1), S11515. De Santi, B., Kim, L., Bulthuis, R. F. G., Lucka, F. & Manohar, S.https://doi.org/10.1117/1.JBO.29.S1.S11515

Research profiles

Prizes and Awards

[1]    Best project Module in TNW 2015-2016 – Microscopisch detective van kanker – elected by students BMT. with Dr. J. Alers module coordinator

[2]    Decentrale Onderwijsprijs 2015 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[3]    Decentrale Onderwijsprijs 2014 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[4]    TNW (Science & Technology) Education Award 2012 for excellence in education in the Biomedical Technology (BMT) Education stream.

[5]    Decentrale Onderwijsprijs 2010 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

 

LIGHT BOARD PROJECT

Developed a DIY Lightboard to give online classes during the COVID-19 pandemic.

Affiliated study programs

Courses academic year 2024/2025

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

Courses academic year 2023/2024

In the press

1) Volkskrant 9 December 2022 "Kan de screening van borstkanker nog beter? Vijf methoden waaraan Nederlandse onderzoekers werken".
2) National Televison (Atlas NTR NPO2) 19 October 2022 "Kun je pijnloos testen op borstkanker?"
3) Health Management (2016) "Dream Imager for Breast Cancer Diagnosis"
4) Volkskrant 4 oktober 2014 "Redt preventieve screening op borstkanker levens?"
5) NRC 22 december 2012 "Batsheba had toch geen borstkanker"

Address

University of Twente

Technohal (building no. 18), room 2380
Hallenweg 5
7522 NH Enschede
Netherlands

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Organisations

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