About Me
Srirang Manohar is Adjunct Professor, Biomedical Photonic Imaging. He has pioneered research into photoacoustic imaging of breast cancer. He also investigates the feasibility of the method in imaging inflammation in joints in rheumatoid arthritis. Prof. Manohar’s research spans technology development to early clinical assessment. The intended applications of the technologies span the range of ex vivo tissue imaging, minimally invasive imaging to non-invasive. He has also done investigations into synthesis and characterization of gold nanoparticles, and in vitro and in vivo application of these and iron oxide nanoparticles in the context of providing contrast for photoacoustics.
Prof. Manohar is the coordinator of the Domain Imaging & Diagnostics at the University of Twente. He also coordinates the H2020 project, PAMMOTH running from 2017-2021. He is also coordinator of the Dutch-India consortium Imaging Needles. He is member of the Organizing Committee for the conference “Photons plus Ultrasound: Imaging and Sensing held annually under auspices of SPIE (Photonics West, San Francisco, USA). He is also member of the Program Committee for the conference Opto-Acoustic Methods & Applications, European Conferences on Biomedical Optics (ECBO), Munich, Germany.
Prof. Manohar is the coordinator of the Domain Imaging & Diagnostics at the University of Twente. He also coordinates the H2020 project, PAMMOTH running from 2017-2021. He is also coordinator of the Dutch-India consortium Imaging Needles. He is member of the Organizing Committee for the conference “Photons plus Ultrasound: Imaging and Sensing held annually under auspices of SPIE (Photonics West, San Francisco, USA). He is also member of the Program Committee for the conference Opto-Acoustic Methods & Applications, European Conferences on Biomedical Optics (ECBO), Munich, Germany.
Expertise
Breast
Imaging Techniques
Imaging Techniques
Gold
Photoacoustic Effect
Neoplasms
Cancer
Tomography
Gold
Organizations
Research
Biomedical imaging specifically photoacoustic imaging for non-invasive and minimally-invasive detection, diagnosis and therapy monitoring of various pathologies including breast cancer and rheumatoid arthritis;
Molecular medicine spanning the trajectory from synthesis, characterization, minimizing cytotoxicity to preclinical applications of antibody conjugated gold nanoparticles for photoacoustic imaging and photothermal therapies.
Publications
Recent
Boink, Y. E., Lagerwerf, M. J., Steenbergen, W., van Gils, S. A., Manohar, S., & Brune, C. (2018). A framework for directional and higher-order reconstruction in photoacoustic tomography. Physics in medicine and biology, 63(4), [045018]. DOI: 10.1088/1361-6560/aaaa4a
Kuniyil Ajith Singh, M., Parameshwarappa, V., Hendriksen, E., Steenbergen, W., & Manohar, S. (2017). Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds. In Photons Plus Ultrasound: Imaging and Sensing 2017 (Vol. 10064). [100640G] SPIE. DOI: 10.1117/12.2252561
Biswas, S. K., van Es, P., Steenbergen, W., & Manohar, S. (2016). A Method for Delineation of Bone Surfaces in Photoacoustic Computed Tomography of the Finger. Ultrasonic imaging, 38(1), 63-76. DOI: 10.1177/0161734615589288
Heijblom, M., Piras, D., van den Engh, F. M., van der Schaaf, M., Klaase, J. M., Steenbergen, W., & Manohar, S. (2016). The state of the art in breast imaging using the Twente Photoacoustic Mammoscope: results from 31 measurements on malignancies. European radiology, 26(11), 3874-3887. DOI: 10.1007/s00330-016-4240-7
Venugopal, M., van Es, P., Manohar, S., Roy, D., & Vasu, R. M. (2016). Quantitative photoacoustic tomography by stochastic search, direct recovery of the optical absorption field. Optics letters, 41(18), 4202-4205. DOI: 10.1364/OL.41.004202
Manohar, S., & Razansky, D. (2016). Photoacoustics: a historical review. Advances in optics and photonics, 8(4), 586-617. DOI: 10.1364/AOP.8.000586
Kuniyil Ajith Singh, M., Parameshwarappa, V., Hendriksen, E., Steenbergen, W., & Manohar, S. (2016). Photoacoustic-guided focused ultrasound for accurate visualization of brachytherapy seeds with the photoacoustic needle. Journal of biomedical optics, 21(12), -. [120501]. DOI: 10.1117/1.JBO.21.12.120501
Grootendorst, D., Fratila, R. M., Pouw, J. J., ten Haken, B., van Wezel, R. J. A., Rottenberg, S., ... Ruers, T. J. M. (2016). photoacoustic staging of nodal metastases using spios: comparison between in vivi, in toto and ex vivo imaging in a rat model. Biomedical spectroscopy and imaging, 5(1), 71-87. DOI: 10.3233/BSI-150127
Groot Nibbelink, M., Daoudi, K., Slegers, S., Grootendorst, D. C., Dantuma, M., Steenbergen, W., ... van Apeldoorn, A. A. (2016). Opening the ‘‘White Box’’ in Tissue Engineering: Visualization of Cell Aggregates in Optically Scattering Scaffolds. Tissue engineering. Part C: Methods, 22(6), 534-542. DOI: 10.1089/ten.tec.2015.0462
Heijblom, M., Steenbergen, W., & Manohar, S. (2015). Clinical Photoacoustic Breast Imaging: The Twente experience. IEEE pulse, 6(3), 42-46. DOI: 10.1109/MPUL.2015.2409102
UT Research Information System
Courses
Contact Details
Visiting Address
University of Twente
Faculty of Science and Technology
Horst Complex
(building no. 20), room ZH265
De Horst 2
7522LW Enschede
The Netherlands
Mailing Address
University of Twente
Faculty of Science and Technology
Horst Complex
ZH265
P.O. Box 217
7500 AE Enschede
The Netherlands