prof.dr. S. Manohar (Srirang)

Srirang Manohar is Professor and Chair, Multi-Modality Medical Imaging (M3I), a new research group. He has pioneered research into photoacoustic imaging of breast cancer. He also investigates the feasibility of the method hybrid with ultrasound imaging in image guidance of Radiofrequency Ablation, imaging ulcers in the diabetic foot, inflammation in joints in rheumatoid arthritis, and imaging of thyroid nodules. Prof. Manohar’s research spans technology development to early clinical assessment. The intended applications of the technologies span the range of ex vivo tissue imaging, minimally-invasive imaging to non-invasive. He has also done investigations into synthesis and characterization of gold nanoparticles, and in vitro and in vivo application of these and iron oxide nanoparticles in the context of providing contrast for photoacoustics.

Prof. Manohar is the coordinator of the Domain Imaging & Diagnostics at the University of Twente. He also coordinates the H2020 project, PAMMOTH running from 2017-2021. He is also coordinator of the Dutch-India consortium Imaging Needles. He is member of the Organizing Committee for the conference “Photons plus Ultrasound: Imaging and Sensing held annually under auspices of SPIE (Photonics West, San Francisco, USA). He is also member of the Program Committee for the conference Opto-Acoustic Methods & Applications, European Conferences on Biomedical Optics (ECBO), Munich, Germany.

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Engineering & Materials Science

# Imaging Techniques
# Phantoms
# Photoacoustic Effect
# Ultrasonics

Physics & Astronomy

# Breast
# Tomography

Medicine & Life Sciences

# Breast
# Radiofrequency Ablation

Biomedical imaging specifically photoacoustic imaging and ultrasound imaging for non-invasive and minimally-invasive detection, diagnosis and therapy monitoring of various pathologies including breast cancer, rheumatoid arthritis, thyroid and the diabetic foot.

De Santi, B., Kim, L., Bulthuis, R. F. G., Lucka, F. , & Manohar, S. (2024). Automated three-dimensional image registration for longitudinal photoacoustic imaging. Journal of biomedical optics, 29(S1), S11515. https://doi.org/10.1117/1.JBO.29.S1.S11515

Boers, T., Brink, W., Bianchi, L., Saccomandi, P. , van Hespen, J., Wennemars, G., Braak, S. , Versluis, M. , & Manohar, S. (2023). An anthropomorphic thyroid phantom for ultrasound-guided radiofrequency ablation of nodules. Medical physics, Article 16906. Advance online publication. https://doi.org/10.1002/mp.16906

Dantuma, M. , Gasteau, D. B. , & Manohar, S. (2023). Photoacoustic spectrum analysis for spherical target size and optical property determination: A feasibility study. Photoacoustics, 32, Article 100534. https://doi.org/10.1016/j.pacs.2023.100534

IPASC (2023). A review of a strategic roadmapping exercise to advance clinical translation of photoacoustic imaging: From current barriers to future adoption. Photoacoustics, 32, Article 100539. https://doi.org/10.1016/j.pacs.2023.100539

Schoustra, S. M. , De Santi, B. , op 't Root, T. J. P. M., Klazen, C. A. H., van der Schaaf, M. C. , Veltman, J. , Steenbergen, W. , & Manohar, S. (2023). Imaging breast malignancies with the Twente Photoacoustic Mammoscope 2. PLoS ONE, 18, Article e0281434. https://doi.org/10.1371/journal.pone.0281434

Boers, T., Braak, S. J., Rikken, N. E. T. , Versluis, M. , & Manohar, S. (2023). Ultrasound imaging in thyroid nodule diagnosis, therapy, and follow‐up: Current status and future trends. Journal of Clinical Ultrasound, 51(6), 1087-1100. https://doi.org/10.1002/jcu.23430

Manohar, S. (2022). Imagination in imaging. University of Twente.

Schoustra, S. M. (2022). A photoacoustic 3D tomographic breast imager: Bench & bedside experiences. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036554169

Thompson, D. (2022). Laser-induced ultrasound transmitters for biomedical imaging. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036554473

Wermelink, B. , Mennes, O. A., Van Baal, J. G. , Steenbergen, W. , Geelkerken, R. H., & study group (2022). Assessing the Microcirculation of the Foot with Laser Speckle Contrast Imaging During Endovascular and Hybrid Revascularisation Procedures in Patients with Chronic Limb Threatening Ischaemia. European journal of vascular and endovascular surgery, 63(6), 898-899. https://doi.org/10.1016/j.ejvs.2022.03.036, https://doi.org/10.1016/j.ejvs.2022.03.036

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Prizes and Awards

[1] Best project Module in TNW 2015-2016 – Microscopisch detective van kanker – elected by students BMT. with Dr. J. Alers module coordinator

[2] Decentrale Onderwijsprijs 2015 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[3] Decentrale Onderwijsprijs 2014 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

[4] TNW (Science & Technology) Education Award 2012 for excellence in education in the Biomedical Technology (BMT) Education stream.

[5] Decentrale Onderwijsprijs 2010 (Best Teacher elected by students) in the Biomedical Technology (BMT) Education stream.

LIGHT BOARD PROJECT

Developed a DIY Lightboard to give online classes during the COVID-19 pandemic.

Bachelor

Biomedische Technologie

Master

Biomedical Engineering

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.