Technohal

prof.dr. S. Siesling (Sabine)

Full Professor
BMS-TPS-HTSR
Technohal 3105
s.siesling@utwente.nl
+31534895638
Business card

Sabine Siesling, clinical epidemiologist, is professor ‘Outcomes Research and Personalized cancer care’ at the University of Twente and senior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. She tailors care and follow-up using/developing prediction models which are based on data from e.g. the Netherlands Cancer registry. She is board member of the National breast cancer working group (NABON) and the NABON Breast cancer audit and PROMS sections, and the European Initiative on Breast cancer Care-Quality assurance Development group. Moreover, she leads the program on Women’s Health at the University of Twente.  


She has been president of the Netherlands Epidemiological Society.  

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Therapeutic Procedure
    • Cancer Registry
    • Survival
    • Neoplasm
    • Hospital
    • Malignant Neoplasm

Organisations

Ancillary activities

  • Integraal Kankercentrum Nederland (IKNL)headresearcher

Publications

2025

Implementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020–2023, using registry data and questionnaires (2025)Radiation Oncology, 20(1). Article 99. Eijkelboom, A. H., van Beek, E. J. A., Stam, M. R., Westhoff, P., van Maaren, M. C., Sattler, M. G. A., Bantema-Joppe, E. J., Verheij, M., van den Bongard, D. H. J. G. & Siesling, S.https://doi.org/10.1186/s13014-025-02669-wThe impact of a mainstream genetic testing pathway and socioeconomic factors on the uptake of germline genetic testing in breast cancer patients: results of the nationwide GENE-SMART study (2025)Breast cancer research, 27(1). Article 129. Jong, C. L. d., Siesling, S., Puts, G. C. W. M., Jager, A. & Ausems, M. G. E. M.https://doi.org/10.1186/s13058-025-02081-yFrom Promise to Practice: Evaluating the Health and Economic Impact of AI in Breast Cancer Imaging Surveillance (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Voets, M.https://doi.org/10.3990/1.9789036568982Disparities in cancer incidence and stage at diagnosis between male and female patients in the Netherlands (2025)European journal of cancer, 230, 116063. Article 116063. Hoveling, L. A., Eijkelboom, A., Schuurman, M., Bode, C., Atema, V., van Laarhoven, H. W. M., Oertelt-Prigione, S., Richters, A., van Asselt, K. M., Siesling, S. & Aarts, M. J.https://doi.org/10.1016/j.ejca.2025.116063Global variation in patterns of care and time to initial treatment for breast, cervical, and ovarian cancer from 2015 to 2018 (VENUSCANCER): a secondary analysis of individual records for 275 792 women from 103 population-based cancer registries in 39 countries and territories (2025)The Lancet, 406(10517), 2325-2348. Allemani, C., Minicozzi, P., Morawski, B., Lima, C. A., Bennett, D., Pongnikorn, D., Petrova, D., Innos, K., Girardi, F., Galán Alvarez, Y., Schaffar, R., Dal Maso, L., Molinié, F., Valkov, M., Phillips, K., Siesling, S., Schultz, A., Daubisse-Marliac, L., Marcos-Gragera, R. & Di Carlo, V.https://doi.org/10.1016/S0140-6736(25)01383-2Patient perceptions around the use of clinico-pathologic and genomic tools in the management of early breast cancer (2025)Breast cancer research and treatment, 214(1), 87-99. Beltran-Bless, A. A., Saunders, D., Clemons, L., Machado, I., Pond, G., Hutton, B., El-Emam, K., McGee, S., Ng, T. L., Savard, M. F., Hilton, J., Rushton, M., Larocque, G., Siesling, S., Leblanc, A., Vandermeer, L. & Clemons, M.https://doi.org/10.1007/s10549-025-07797-1Trends in Surgical Treatment for cT4 Breast Cancer After Neoadjuvant Systemic Therapy: A Nationwide Study in The Netherlands (2025)Annals of surgical oncology, 32(12), 8668-8677. Jansen, B. A. M., Kelder, J. C., Borchert, T., van Uden, D. J. P., van der Leij, F., Schröder, C., Doeksen, A., Siesling, S., van Maaren, M. C. & Postma, E. L.https://doi.org/10.1245/s10434-025-17585-2Trends in use of magnetic resonance imaging and partial breast irradiation between 2011–2022 in the Netherlands: A population-based study (2025)Clinical and Translational Radiation Oncology, 55. Article 101039. Civil, Y. A., Eijkelboom, A. H., Veldink, A. E., van Maarenc, M. C., Maduro, J. H., Duvivier, K. M., Siesling, S. & van den Bongard, H. J. G. D.https://doi.org/10.1016/j.ctro.2025.101039Understanding delays in breast cancer diagnosis in Africa: Key insights and contributing factors (2025)International journal of cancer, 157(9), 1830-1840. Hoveling, L. A., Heuken, L. P., Harfst, T., Schuurman, M. S., van Asselt, K. M., Siesling, S. & Bode, C.https://doi.org/10.1002/ijc.70008Breast cancer-related fatigue risk and intervention recommendations: What can and cannot be personalised? (2025)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Beenhakker, L.https://doi.org/10.3990/1.9789036568425Overall survival of patients with de Novo HER2-positive metastatic breast cancer in the Netherlands from 2008 to 2017: A population-based cohort study of systemically treated patients (2025)European journal of cancer, 222. Article 115475. Ding, N., Hermans, K. E. P. E., van Nijnatten, T. J. A., Engelen, S. M. E., Tol, J., Kooreman, L., Vrancken-Peeters, M.-J. T. F. D., Siesling, S., Voogd, A. C., Tjan-Heijnen, V. C. G. & Geurts, S. M. E.https://doi.org/10.1016/j.ejca.2025.115475A holistic profile for cancer-related fatigue for women with breast cancer–a qualitative study (2025)Psychology & health, 40(6), 1037-1061. Wijlens, K. A. E., Beenhakker, L., Witteveen, A., Siemerink, E. J. M., Jansen, L., Gernaat, C., Schellekens, M. P. J., Siesling, S., Vollenbroek-Hutten, M. M. R. & Bode, C.https://doi.org/10.1080/08870446.2023.2289457Different needs ask for different care: Breast cancer patients’ preferences regarding assessment of care needs and information provision in personalized aftercare (2025)European journal of oncology nursing, 76. Article 102873. Dekker-Klaassen, A., Drossaert, C. H. C., Folkert, L. S., van der Lee, M. L., Guerrero-Paez, C., Claassen, S., Korevaar, J. C., Siesling, S., Maaren, M. v., Retel, V., Leeuwen, E. v., Knottnerus, B., Burgers, J., Vrancken, M. J., Siemerink, E., Honkoop, A., Veltman, J., Zeillemaker, A., Mann, R., … Hezewijk, M. v.https://doi.org/10.1016/j.ejon.2025.102873Five-year conditional relative survival up to 10 years post-diagnosis among adolescent and young adult breast cancer patients by age, stage, and receptor subtype (2025)Journal of the National Cancer Center, 5(3), 297-305. Vrancken Peeters, N. J. M. C., van der Meer, D. J., Kok, M., van Maaren, M. C., Baas-Vrancken Peeters, M.-J. T. F. D., Siesling, S., van der Graaf, W. T. A. & Husson, O.https://doi.org/10.1016/j.jncc.2025.01.005Notification of locoregional breast cancer recurrence based on pathology reports: A nationwide validation study with the Netherlands Cancer Registry (2025)Cancer epidemiology, 96. Article 102780. van Maaren, M. C., Voorham, Q. J. M., Wijnen, E. M., de Munck, L., Wesseling, J., Visser, O. & Siesling, S.https://doi.org/10.1016/j.canep.2025.102780The added value of physical examination for breast cancer recurrence detection in women: A systematic review (2025)Clinical breast cancer, 25(4), e383-e393.e2. Godding, L. T. H., Klaassen-Dekker, A., Volders, J. H., van Hezewijk, M., Siemerink, E. J. M., van Uden, D., Veltman, J., Eijkelboom, A. & Siesling, S.https://doi.org/10.1016/j.clbc.2024.12.014Considerations to forgo systemic treatment in patients with advanced esophageal or gastric cancer: A real‐world evidence study (2025)International journal of cancer, 156(10), 1950-1960. Slotman, E., Pape, M., van Laarhoven, H. W. M., Pouw, R. E., van der Linden, Y. M., Verhoeven, R. H. A., Siesling, S., Fransen, H. P. & Raijmakers, N. J. H.https://doi.org/10.1002/ijc.35314ASO Author Reflections: Sentinel Lymph Node Biopsy for Patients with a Non-classic Lobular Carcinoma In Situ Breast Biopsy (2025)Annals of surgical oncology, 32, 2597-2598. Article 113500. Westenend, P. J., Meurs, C. J. C., Siesling, S. & Menke-Pluijmers, M. B. E.https://doi.org/10.1245/s10434-024-16863-9ASO Visual Abstract: Surgery for Classic, Pleomorphic and Nonclassic Lobular Carcinoma In Situ Surgery Rate, Risk of Upstaging and Short-Term Follow-Up (2025)Annals of surgical oncology, 32(4), 2610-2611. Meurs, C. J. C., Kerkhoven, C., Siesling, S., Menke-Pluijmers, M. B. E. & Westenend, P. J.https://doi.org/10.1245/s10434-025-16906-9Development of machine learning models to predict cancer-related fatigue in Dutch breast cancer survivors up to 15 years after diagnosis (2025)Journal of cancer survivorship, 19(2), 580-593. Beenhakker, L., Wijlens, K. A. E., Witteveen, A., Heins, M., Korevaar, J. C., de Ligt, K. M., Bode, C., Vollenbroek-Hutten, M. M. R. & Siesling, S.https://doi.org/10.1007/s11764-023-01491-1

Research profiles

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