Technohal

prof.dr. S. Siesling (Sabine)

Full Professor
BMS-TPS-HTSR
Technohal 3105
s.siesling@utwente.nl
+31534895638
Business card

Sabine Siesling, clinical epidemiologist, is professor ā€˜Outcomes Research and Personalized cancer careā€™ at the University of Twente andā€Æsenior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. She tailors care and follow-up using/developing prediction models which are based on data from e.g. the Netherlands Cancer registry. She is board member of the National breast cancer working group (NABON) and the NABON Breast cancer audit and PROMS sections, and the European Initiative on Breast cancer Care-Quality assurance Development group. Moreover, she leads the program on Womenā€™s Health at the University of Twente.Ā Ā 


She has been president of the Netherlands Epidemiological Society.Ā Ā 

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Cancer Registry
    • Tumor
    • Recurrent Disease
    • Radiation Therapy
    • Overall Survival
    • Systemic Therapy

  • Nursing and Health Professions

    • Malignant Neoplasm

Organisations

Ancillary activities

  • Integraal Kankercentrum Nederland (IKNL)head researcher

Publications

2026

Development of an algorithm to support cancer registry registration by identifying patients with metachronous metastases after primary breast cancer (2026)ESMO Real World Data and Digital Oncology, 14. Article 100811. de Munck, L., Buisman, H., Verloop, J. & Siesling, S.https://doi.org/10.1016/j.esmorw.2026.100811Radiation therapy trends following breast-conserving surgery in early-stage estrogen receptor-positive breast cancer: particularly in older patients more frequently omitted (2026)The Breast, 89. Article 104893. Bouwman, L., Blok, E. J., Scholten, A. N., Siesling, S., Portielje, J. E. A. & Liefers, G. J.https://doi.org/10.1016/j.breast.2026.104893Factors associated with local breast cancer recurrence after mastectomy in the Netherlands: a retrospective nationwide cohort study (2026)The Breast, 88. Article 104844. Stindt, T. D. A., van Maaren, M. C., Offersen, B. V., Siesling, S., van Uden, D. J. P., Poortmans, P. M. P., Boersma, L. J. & Kaidar-Person, O.https://doi.org/10.1016/j.breast.2026.104844The relevance of cancer type specific scenarios in predicting primary radiotherapy use in non-metastatic cancer patients in the Netherlands towards 2032 (2026)Clinical oncology, 56. Article 104211. Struikmans, H., Evers, J., Bauhuis, J. W., Bloemers, C. W. M. M., Dirkx, M. L. P., Doornaert, P. A. H., Minken, A. W. H., van der Sangen, M. J. C., Siesling, S., Slotman, B. J., Bijlsma, M. J. & Aarts, M. J.https://doi.org/10.1016/j.clon.2026.104211Real-world systemic therapy utilization and survival in synchronous metastatic solid cancer: A comprehensive nationwide analysis (2026)[Working paper › Preprint]. MedRxiv. Slotman, E., van Disseldorp, L. M., de Jong, G., Fransen, H. P., Reyners, A. K. L., Tol, J., Jager, A., Westgeest, H. M., Sonke, G. S., van Laarhoven, H. W. M., van Zuylen, L., van den Heuvel, M. M., Koopman, M., Smit, E., Raijmakers, N. J. H. & Siesling, S.https://doi.org/10.64898/2026.07.20.26358468Risicofactoren voor diagnostische vertraging bij borstkanker (2026)Huisarts en Wetenschap. Hoveling, L., Schuurman, M., Siesling, S., Bode, C. & Van Asselt, K. M.Impact of Reimbursement on the Utilisation of Gene Expression Profiles and Chemotherapy Decisionā€Making in Dutch Breast Cancer Patients: A Populationā€Based Study (2026)International journal of cancer, 159(10), 2485-2497 (E-pub ahead of print/First online). Meijer, J., Hermanns, N., Bijlsma, R., Blommestein, H. M., van den Bongard, D. H. J. G., van Dalen, T., van Diest, P. J., Drukker, C. A., Guerrero Paez, C., Honkoop, A. H., Jager, A., Koppert, L. B., Linn, S. C., van Maaren, M. C., Siemerink, E. J., van ’t Veer, L. J., Volders, J. H., Vrancken Peeters, M. J. & Siesling, S.https://doi.org/10.1002/ijc.70571Characteristics, treatment and survival in de novo and metachronous metastatic breast cancer: A nationwide comparative analysis (2026)Breast cancer research and treatment, 217(2). Article 33. Slotman, E., de Munck, L., Jager, A., Honkoop, A. H., Siemerink, E. J. M., Heijns, J. B., van der Wall, E., Raijmakers, N. J. H., Fransen, H. P. & Siesling, S.https://doi.org/10.1007/s10549-026-07979-5External validation of PREDICT Breast v3.1 for overall survival in international cohorts, including young and invasive lobular subgroups (2026)Breast cancer research and treatment, 217(2). Article 14. Verheul, E. M., Doornkamp, F., Petrov, I., Siesling, S., Lingsma, H. F., Koppert, L. B., Vreven, L. W. A., Voogd, A. C., Karsten, M. M., Doppelbauer, L., Gebert, P., Kiani, N., Borstnar, S., Pharoah, P. D. P., Hedayati, E., Steyerberg, E. W., van Klaveren, D., Puértolas, T., Nwosu, A. C., ā€¦ Frank, K.https://doi.org/10.1007/s10549-026-07958-wInternational comparisons of survival after recurrent metastatic breast cancer in four countries: A population-based study (2026)The Breast, 87, 104778. Article 104778. Fink, H., Soerjomataram, I., Bardot, A., Brennan, A., Woods, R. R., Gonsalves, L., Nygård, J. F., Negoita, S., Ramirez-Pena, E., Gelmon, K., Siesling, S., Cardoso, F., Gralow, J. & Morgan, E.https://doi.org/10.1016/j.breast.2026.104778Margin status after breast-conserving surgery for breast cancer in the Netherlands from 2009 to 2022 (2026)BJS open, 10(3). Article zrag063. Nijveldt, J. J., Keizers, B., Siesling, S., Francken, A. B., Rajan, K. K., de Haas, A. H., van der Vegt, B., Koppert, L. B., Kruijff, S., van der Zaag, P. J., Kelder, W., Beek, M. A., Schuttevaer, H. A., Schok, T., Rakhorst, H. A., Jansen, L., van Hezewijk, M., van Deurzen, C. H. M., Volders, J. H., ā€¦ Gooiker, G. A.https://doi.org/10.1093/bjsopen/zrag063Balancing burden and benefit in advanced cancer: Real-world insights into treatment considerations, patterns and outcomes (2026)[Thesis › PhD Thesis - Research external, graduation UT]. University of Twente. Slotman, E.https://doi.org/10.3990/1.9789036571357Interactive symptom monitoring and coaching to optimise toxicity management of chemo(immune)therapy in early stage breast cancer: study protocol of the multicentre randomised controlled eChemoCoach trial (2026)BMC cancer, 26(1). Article 571 (E-pub ahead of print/First online). Verduin, R. J. T., van den Hurk, C. J. G., van Maurik, I. S., Nota, N. M., van Leeuwen-Stok, A. E., Komen, M. M. C., Jager, A., Drossaert, C. H. C., Siesling, S. & Hendriks, M. P.https://doi.org/10.1186/s12885-026-15905-7Breast cancer: Global Quality care (2026)Belgian journal of medical oncology, 20(2), 77-78. Verhoeven, D., Kaufman, C., Roy, P. & Siesling, S.https://www.bjmo.be/journal-article/breast-cancer-global-quality-care/The Personalized cAnceR TreatmeNt and caRe (PARTNR) project: Optimizing intervention recommendations for breast cancer-related fatigue (2026)[Contribution to conference › Poster] TechMed Research Day 2026. Wijlens, K. A. E., Bode, C., Siesling, S., Vollenbroek-Hutten, M. M. R. & Witteveen, A.Development and validation of prediction models for health-related quality of life outcomes after breast cancer surgery and reconstruction (2026)European journal of surgical oncology, 52(4). Article 111466. Verheul, E. M., Karsten, M. M., Gebert, P., Doppelbauer, L., Borstnar, S., Siesling, S., Lingsma, H. F., Vrancken-Peeters, N. J. M. C., Stiggelbout, A. M., Mureau, M. A. M., Koppert, L. B., van Klaveren, D., Bak, M., de Wreede, L. C., Frank, K., Hartman, L., Hedayati, E., Hackmann, T., Hallsson, L. R., ā€¦ Wouters, M. W.https://doi.org/10.1016/j.ejso.2026.111466Impact of screening on late-stage breast cancer in the Netherlands: a population-based cohort study (2007-2016) (2026)The Breast, 86. Article 104745. Li, Y., Sidorenkov, G., Wang, J., Greuter, M. J. W., Houssami, N., Dorrius, M. D., Siesling, S., de Munck, L. & de Bock, G. H.https://doi.org/10.1016/j.breast.2026.104745Breast Cancer: Global Quality Care (2026)[Book/Report › Book editing]. Oxford University Press. Verhoeven, D., Kaufman, C. S., Roy, P. & Siesling, S.https://doi.org/10.1093/med/9780198911296.001.0001Preface (2026)In Breast Cancer: Global Quality Care (pp. V-VII). Oxford University Press. Verhoeven, D., Kaufman, C., Roy, P. & Siesling, S.Breast cancer: Global quality care (2026)[Book/Report › Book editing]. Oxford University Press. Verhoeven, D., Kaufman, C., Roy, P. & Siesling, S.https://doi.org/10.1093/med/9780198911296.001.0001

Research profiles

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