Sabine Siesling, clinical epidemiologist, is professor ‘Outcomes Research and Personalized cancer care’ at the University of Twente and senior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. She tailors care and follow-up using/developing prediction models which are based on data from e.g. the Netherlands Cancer registry. She is board member of the National breast cancer working group (NABON) and the NABON Breast cancer audit and PROMS sections, and the European Initiative on Breast cancer Care-Quality assurance Development group. Moreover, she leads the program on Women’s Health at the University of Twente.  


She has been president of the Netherlands Epidemiological Society.  

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Therapeutic Procedure
    • Survival
    • Cancer Registry
    • Neoplasm
    • Hospital
    • Malignant Neoplasm

Organisations

Ancillary activities

  • Integraal Kankercentrum Nederland (IKNL)headresearcher

Publications

2024

Data-driven decision support for multidisciplinary clinical decision-making & reporting in breast cancer (2024)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Hendriks, M. P.https://doi.org/10.3990/1.9789036563390Long-term outcomes of young, node-negative, chemotherapy-naïve, triple-negative breast cancer patients according to BRCA1 status (2024)BMC Medicine, 22. Article 9. Wang, Y., Dackus, G. M. H. E., Rosenberg, E. H., Cornelissen, S., de Boo, L. W., Broeks, A., Brugman, W., Chan, T. W. S., van Diest, P. J., Hauptmann, M., ter Hoeve, N. D., Isaeva, O. I., de Jong, V. M. T., Jóźwiak, K., Kluin, R. J. C., Kok, M., Koop, E., Nederlof, P. M., Opdam, M., … Schmidt, M. K.https://doi.org/10.1186/s12916-023-03233-7Symptom Monitoring and Health-Related Quality of Life in Non-metastatic Breast Cancer Patients: A Systematic Review (2024)Current Breast Cancer Reports, 16(4), 417-428. Vrancken Peeters, N. J. M. C., Koppert, L. B., Jager, A., Hendriks, M. P., Siesling, S. & van den Hurk, C. J. G.https://doi.org/10.1007/s12609-024-00562-1Guidelines versus real-world data in metastatic bladder cancer: A population-based study on first-line chemotherapy treatment patterns (2024)Urologic Oncology (E-pub ahead of print/First online). Slotman, E., Richters, A., Fransen, H. P., Smilde, T. J., van der Linden, Y. M., Siesling, S., Aben, K. K. H. & Raijmakers, N. J. H.https://doi.org/10.1016/j.urolonc.2024.10.026The INFLUENCE 3.0 model: updated predictions of locoregional recurrence and contralateral breast cancer, now also suitable for patients treated with neoadjuvant systemic therapy (2024)The Breast, 79. Article 103829 (E-pub ahead of print/First online). van Maaren , M. C., Hueting, T. A., van Uden, D. J. P., van Hezewijk, M., de Munck, L., Mureau, M. A. M., Seegers, P. A., Voorham, Q. J. M., Schmidt, M. K., Sonke, G. S., Groothuis-Oudshoorn, C. G. M. & Siesling, S.https://doi.org/10.1016/j.breast.2024.103829Adherence to guideline recommendations for follow-up in patients with DCIS at a large teaching hospital in the Netherlands (2024)Breast cancer research and treatment, 207(3), 633-640. Rajan, K. K., Nijveldt, J. J., Verheijen, S., Siesling, S., Beek, M. A. & Francken, A. B.https://doi.org/10.1007/s10549-024-07391-xCollecting Long-Term Outcomes in Population-Based Cancer Registry Data: The Case of Breast Cancer Recurrence (2024)JCO Global Oncology, 10. Article e2400249. Morgan, E., O'Neill, C., Bardot, A., Walsh, P., Woods, R. R., Gonsalves, L., Hawkins, S., Nygård, J. F., Negoita, S., Ramirez-Pena, E., Gelmon, K., Siesling, S., Cardoso, F., Gralow, J., Soerjomataram, I. & Arnold, M.https://doi.org/10.1200/GO-24-00249Face and content validity of a holistic assessment questionnaire to assess cancer-related fatigue after breast cancer (2024)Fatigue: Biomedicine, Health and Behavior, 12(4), 293-307. Wijlens, K. A. E., Witteveen, A., Beenhakker, L., Siemerink, E. J. M., Achterkamp, R., Siesling, S., Vollenbroek-Hutten, M. M. R. & Bode, C.https://doi.org/10.1080/21641846.2024.238900770-Gene signature-guided adjuvant systemic treatment adjustments in early-stage ER+ breast cancer patients: 7-year follow-up of a prospective multicenter cohort study (2024)Breast cancer research and treatment (E-pub ahead of print/First online). Verreck, E. E. F., Kuijer, A., van Steenhoven, J. E. C., Volders, J. H., van der Velden, A. W. G., Siesling, S., Timmer-Bonte, A. N. H., Smilde, T. J., Imholz, A. L. T., Blanken-Peeters, C. F. J. M., de Valk, B., Vrijaldenhoven, S., Lastdrager, W. B., Haringhuizen, A. W., Hunting, J. C. B., Hovenga, S., Nieboer, P., Zuetenhorst, H. M., Tetteroo, G. W. M., … van Dalen, T.https://doi.org/10.1007/s10549-024-07496-3Surgical outcomes and prognosis of HER2+ invasive breast cancer patients with a DCIS component treated with breast-conserving surgery after neoadjuvant systemic therapy (2024)European journal of surgical oncology, 50(9). Article 108465. Ploumen, R. A. W., Claassens, E. L., Kooreman, L. F. S., Keymeulen, K., van Kats, M. A. C. E., van Kuijk, S. M. J., Siesling, S., van Nijnatten, T. J. A. & Smidt, M. L.https://doi.org/10.1016/j.ejso.2024.108465Radiotherapy Trends and Variations in Invasive Non-metastatic Breast Cancer Treatment in the Netherlands: A Nationwide Overview From 2008 to 2019 (2024)Clinical oncology (E-pub ahead of print/First online). Evers, J., van der Sangen, M. J. C., van Maaren, M. C., Maduro, J. H., Strobbe, L., Aarts, M. J., Bloemers, M. C. W. M., van den Bongard, D. H. J. G., Struikmans, H. & Siesling, S.https://doi.org/10.1016/j.clon.2024.08.010Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy (2024)JAMA Oncology, 10(8), 1077-1086. Geurts, V. c. m., Balduzzi, S., Steenbruggen, T. g., Linn, S. c., Siesling, S., Badve, S. s., Demichele, A., Ignatiadis, M., Leon-Ferre, R. a., Goetz, M. P., Wolff, A. c., Klar, N., Michiels, S., Loi, S., Adams, S., Horlings, H. m., Sonke, G. s., Salgado, R. & Kok, M.https://doi.org/10.1001/jamaoncol.2024.1917Een korte, praktische vragenlijst voor borstkankerpatiënten in de klinische praktijk: een aanpassing van de NABON MiniPROM (2024)Nederlands Tijdschrift voor Oncologie, 21, 45-50 (Accepted/In press). De Rooij, B. H., de Ligt, K., Verloop, J., Ezendam, N. P. M., Honkoop, A., Boersma, L. J., Schlooz-Vries, M., Siesling, S., Bessems, M. & Zeestraten, E.A comparison of treatment allocation and survival between younger and older patients with HER2-overexpressing de novo metastatic breast cancer (2024)Journal of geriatric oncology, 15(6). Article 101805. Lemij, A., de Glas, N., Kroep, J., Siesling, S., van den Bos, F., Bastiaannet, E., Liefers, G. J. & Portielje, J.https://doi.org/10.1016/j.jgo.2024.101805High-value breast cancer care within resource limitations (2024)Oncologist, 29(7), e899-e909. Verhoeven, D., Siesling, S., Allemani, C., Roy, P., Travado, L., Bhoo-Pathy, N., Rhayns, C., Junkermann, H., Nakamura, S., Lasebikan, N. & Tucker, F.https://doi.org/10.1093/oncolo/oyae080Implementation of ultra-hypofractionated radiotherapy schedules for breast cancer during the COVID-19 pandemic in the Netherlands (2024)Clinical and Translational Radiation Oncology, 47. Article 100807. Eijkelboom, A. H., Stam, M. R., van den Bongard, D. H. J. G., Sattler, M. G. A., Bantema-Joppe, E. J., Siesling, S. & van Maaren, M. C.https://doi.org/10.1016/j.ctro.2024.100807Information and communication priorities of patients and healthcare professionals in shared decision making regarding adjuvant systemic breast cancer treatment: A survey study (2024)European journal of oncology nursing, 70. Article 102574. Damman, O. C., van Strien-Knippenberg, I. S., Engelhardt, E. G., Determann, D., Bruijne, M. C. D., Siesling, S., Konings, I. R. & Timmermans, D. R. M.https://doi.org/10.1016/j.ejon.2024.102574Internal Responsiveness of EQ-5D-5L and EORTC QLQ-C30 in Dutch Breast Cancer Patients during the First Year Post-Surgery: A Longitudinal Cohort Study (2024)Cancers, 16(11), 1952. Article 1952. Vrancken Peeters, N. J. M. C., van Til, J. A., Huberts, A. S., Siesling, S., Husson, O. & Koppert, L. B.https://doi.org/10.3390/cancers16111952Opportunities for personalised follow-up in breast cancer: the gap between daily practice and recurrence risk (2024)Breast cancer research and treatment, 205, 313-322. Voets, M., Hassink, N., Veltman, J., Slump, C. H., Koffijberg, H. & Siesling, S.https://doi.org/10.1007/s10549-024-07246-5Continuity of care for patients with de novo metastatic cancer during the COVID-19 pandemic: A population-based observational study (2024)International journal of cancer, 154(10), 1786-1793. Slotman, E., Weijzen, F., Fransen, H. P., van Hoeve, J. C., Huijben, A. M. T., Kuip, E. J. M., Jager, A., Kunst, P. W. A., van Laarhoven, H. W. M., Tol, J., Tjan-Heijnen, V. C. G., Raijmakers, N. J. H., van der Linden, Y. M. & Siesling, S.https://doi.org/10.1002/ijc.34857

Research profiles

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