Technohal

prof.dr. S. Siesling (Sabine)

Full Professor
BMS-TPS-HTSR
Technohal 3105
s.siesling@utwente.nl
+31534895638
Business card

Sabine Siesling, clinical epidemiologist, is professor ‘Outcomes Research and Personalized cancer care’ at the University of Twente and senior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. She tailors care and follow-up using/developing prediction models which are based on data from e.g. the Netherlands Cancer registry. She is board member of the National breast cancer working group (NABON) and the NABON Breast cancer audit and PROMS sections, and the European Initiative on Breast cancer Care-Quality assurance Development group. Moreover, she leads the program on Women’s Health at the University of Twente.  


She has been president of the Netherlands Epidemiological Society.  

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Therapeutic Procedure
    • Cancer Registry
    • Survival
    • Neoplasm
    • Malignant Neoplasm
    • Recurrent Disease

Organisations

Ancillary activities

  • Integraal Kankercentrum Nederland (IKNL)head researcher

Publications

Jump to: 2026 | 2025

2026

Balancing burden and benefit in advanced cancer: Real-world insights into treatment considerations, patterns and outcomes (2026)[Thesis › PhD Thesis - Research external, graduation UT]. University of Twente. Slotman, E.https://doi.org/10.3990/1.9789036571357Characteristics, treatment and survival in de novo and metachronous metastatic breast cancer: A nationwide comparative analysis (2026)Breast cancer research and treatment, 217(2). Article 33 (E-pub ahead of print/First online). Slotman, E., de Munck, L., Jager, A., Honkoop, A. H., Siemerink, E. J. M., Heijns, J. B., van der Wall, E., Raijmakers, N. J. H., Fransen, H. P. & Siesling, S.https://doi.org/10.1007/s10549-026-07979-5Breast cancer: Global Quality care (2026)Belgian journal of medical oncology, 20(2), 77-78. Verhoeven, D., Kaufman, C., Roy, P. & Siesling, S.https://www.bjmo.be/journal-article/breast-cancer-global-quality-care/The Personalized cAnceR TreatmeNt and caRe (PARTNR) project: Optimizing intervention recommendations for breast cancer-related fatigue (2026)[Contribution to conference › Poster] TechMed Research Day 2026. Wijlens, K. A. E., Bode, C., Siesling, S., Vollenbroek-Hutten, M. M. R. & Witteveen, A.International comparisons of survival after recurrent metastatic breast cancer in four countries: A population-based study (2026)The Breast, 87, 104778. Article 104778 (E-pub ahead of print/First online). Fink, H., Soerjomataram, I., Bardot, A., Brennan, A., Woods, R. R., Gonsalves, L., Nygård, J. F., Negoita, S., Ramirez-Pena, E., Gelmon, K., Siesling, S., Cardoso, F., Gralow, J. & Morgan, E.https://doi.org/10.1016/j.breast.2026.104778Development and validation of prediction models for health-related quality of life outcomes after breast cancer surgery and reconstruction (2026)European journal of surgical oncology, 52(4). Article 111466. Verheul, E. M., Karsten, M. M., Gebert, P., Doppelbauer, L., Borstnar, S., Siesling, S., Lingsma, H. F., Vrancken-Peeters, N. J. M. C., Stiggelbout, A. M., Mureau, M. A. M., Koppert, L. B., van Klaveren, D., Bak, M., de Wreede, L. C., Frank, K., Hartman, L., Hedayati, E., Hackmann, T., Hallsson, L. R., … Wouters, M. W.https://doi.org/10.1016/j.ejso.2026.111466Impact of screening on late-stage breast cancer in the Netherlands: a population-based cohort study (2007-2016) (2026)The Breast, 86. Article 104745. Li, Y., Sidorenkov, G., Wang, J., Greuter, M. J. W., Houssami, N., Dorrius, M. D., Siesling, S., de Munck, L. & de Bock, G. H.https://doi.org/10.1016/j.breast.2026.104745Breast Cancer: Global Quality Care (2026)[Book/Report › Book editing]. Oxford University Press. Verhoeven, D., Kaufman, C. S., Roy, P. & Siesling, S.https://doi.org/10.1093/med/9780198911296.001.0001Preface (2026)In Breast Cancer: Global Quality Care (pp. V-VII). Oxford University Press. Verhoeven, D., Kaufman, C., Roy, P. & Siesling, S.Breast cancer incidence, by stage at diagnosis, and mortality in 21 European countries in the era of mammography screening: an international population-based study (2026)The Lancet Regional Health - Europe, 62. Article 101574. Cardoso, R., Ola, I., Jansen, L., Hackl, M., Ihle, P., Francart, J., Van Damme, N., Valerianova, Z., Atanasov, T., Májek, O., Ngo, O., Innos, K., Mägi, M., Yonli, S. D., Woronoff, A. S., Tretarre, B., Poncet, F., Katalinic, A., Walsh, P. M., … Brenner, H.https://doi.org/10.1016/j.lanepe.2025.101574Nazorg bij en na kanker (2026)In Probleemgeoriënteerd denken in de oncologie (pp. 57-65). Uitgeverij Boom. Siesling, S., Korevaar, J. C., van der Lee, M. & Velthuis, M. J.Comparative validation of PREDICT versions 3.1 and 2.2 for overall survival in the Dutch breast cancer population (2026)The Breast, 85. Article 104681. Vreven, L. W. A., Verheul, E. M., van Maaren, M. C., Doornkamp, F., Schipper, R.-J., Siesling, S., Pharoah, P. D. P., Tjan-Heijnen, V. C. G. & Voogd, A. C.https://doi.org/10.1016/j.breast.2025.104681Less endocrine therapy in HR+/HER2- breast cancer: a nationwide trend despite unchanged guidelines (2026)The Breast, 85. Article 104664. Verreck, E. E. F., Postma, E. L., Oostergo, T., Meijer, J., Eijkelboom, A., Siesling, S., Rizopoulos, D., van Dalen, T. & Volders, J. H.https://doi.org/10.1016/j.breast.2025.104664Trends in local, regional and contralateral breast tumor recurrence within five years after diagnosis in the Netherlands: A population-based study including 121347 patients (2026)The Breast, 85. Article 104673. Meijer, J., van den Bongard, H. J. G. D., Koppert, L. B., Menke-van der Houven van Oordt, C. W., de Munck, L., van Nijnatten, T. J. A., van der Sangen, M. J. C., Schipper, R. J., Schmidt, M. K., Smidt, M. L., Vreuls, W., van Maaren, M. C. & Siesling, S.https://doi.org/10.1016/j.breast.2025.104673Acute toxicity and quality of life after 5-fraction versus 15-fraction adjuvant radiotherapy following conventional or oncoplastic breast-conserving surgery − a real-world prospective cohort study (2026)Radiotherapy and oncology, 214. Article 111310. Mink van der Molen, D. R., Batenburg, M. C. T., van ’t Westeinde, T., Houweling, A. C., Maarse, W., Verhoeven, K., Strijbos, J., Murrer, L., Siesling, S., Monninkhof, E. M., Verkooijen, H. M., Boersma, L. J. & van der Leij, F.https://doi.org/10.1016/j.radonc.2025.111310Breast cancer: Global quality care (2026)[Book/Report › Book editing]. Oxford University Press. Verhoeven, D., Kaufman, C., Mansel, R. & Siesling, S.

2025

Primary tumour response on breast MRI as a predictor of axillary pathologic response in breast cancer patients treated with neoadjuvant chemotherapy (2025)European radiology (E-pub ahead of print/First online). van Amstel, F. J. G., van Mierlo, R. G. M., Nelemans, P. J., Engelen, S. M. E., Houwers, J., Kooreman, L. F. S., Tjan-Heijnen, V. C. G., Siesling, S., Smidt, M. L. & van Nijnatten, T. J. A.https://doi.org/10.1007/s00330-025-12249-xImplementation of ultra-hypofractionated radiotherapy for breast cancer in the Netherlands in 2020–2023, using registry data and questionnaires (2025)Radiation Oncology, 20(1). Article 99. Eijkelboom, A. H., van Beek, E. J. A., Stam, M. R., Westhoff, P., van Maaren, M. C., Sattler, M. G. A., Bantema-Joppe, E. J., Verheij, M., van den Bongard, D. H. J. G. & Siesling, S.https://doi.org/10.1186/s13014-025-02669-wMargin status after breast-conserving surgery for breast cancer in the Netherlands from 2009-2022 – room for improvement (2025)European journal of surgical oncology, 51(Suppl. 2), 110551. Nijveldt, J., Keizers, B., Siesling, S., Francken, A. B., Rajan, K., de Haas, S., van der Vegt, B., Koppert, L., Kruijff, S., van der Zaag, P. & Kelder, W.https://doi.org/10.1016/j.ejso.2025.110551Pathological complete response and survival after neoadjuvant chemotherapy in patients with stage I TNBC: a registry-based study (2025)ESMO Open, 10(12). Article 105923. de Graaf, M., Gielen, R. C. A. M., Balduzzi, S., Siesling, S., Linn, S. C. & Kok, M.https://doi.org/10.1016/j.esmoop.2025.105923

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