Technohal

prof.dr. S. Siesling (Sabine)

Full Professor
BMS-TPS-HTSR
Technohal 3105
s.siesling@utwente.nl
+31534895638
Business card

Sabine Siesling, clinical epidemiologist, is professor ā€˜Outcomes Research and Personalized cancer careā€™ at the University of Twente andā€Æsenior researcher at the Netherlands Comprehensive Cancer Organisation (IKNL). She focusses on the effect of interventions, such as care pathways or implementation of new technologies, on the quality, organisation and outcome of cancer care. She tailors care and follow-up using/developing prediction models which are based on data from e.g. the Netherlands Cancer registry. She is board member of the National breast cancer working group (NABON) and the NABON Breast cancer audit and PROMS sections, and the European Initiative on Breast cancer Care-Quality assurance Development group. Moreover, she leads the program on Womenā€™s Health at the University of Twente.Ā Ā 


She has been president of the Netherlands Epidemiological Society.Ā Ā 

Expertise

  • Medicine and Dentistry

    • Breast Cancer
    • Patient
    • Therapeutic Procedure
    • Cancer Registry
    • Survival
    • Neoplasm
    • Hospital
    • Malignant Neoplasm

Organisations

Ancillary activities

  • Integraal Kankercentrum Nederland (IKNL)headresearcher

Publications

Jump to: 2025 | 2024

2025

Diagnostic delay in women with cancer: What do we know and which factors contribute? (2025)The Breast, 80. Article 104427. Hoveling, L. A., Schuurman, M., Siesling, S., van Asselt, K. M. & Bode, C.https://doi.org/10.1016/j.breast.2025.104427The effect of neoadjuvant chemotherapy on ductal carcinoma in situ in triple-negative breast cancer patients: A nationwide analysis (2025)The Breast, 80. Article 104425. Claassens, E. L., Ploumen, R. A. W., Kooreman, L. F. S., van Kats, M. A. C. E., Siesling, S., van Nijnatten, T. J. A. & Smidt, M. L.https://doi.org/10.1016/j.breast.2025.104425Patient-reported outcomes after immediate and delayed DIEP-flap breast reconstruction in the setting of post-mastectomy radiation therapyā€”results of the multicenter UMBRELLA breast cancer cohort (2025)Breast cancer research and treatment (E-pub ahead of print/First online). Jansen, B. A. M., Bargon, C. A., Bouman, M. A., Mink van der Molen, D. R., Postma, E. L., van der Leij, F., Zonnevylle, E., Ruhe, Q., Bruekers, S. E., Maarse, W., Siesling, S., Young-Afat, D. A., Doeksen, A. & Verkooijen, H. M.https://doi.org/10.1007/s10549-025-07613-wDeintensification of Radiotherapy Use in Treatment of Ductal Carcinoma In Situ in the Netherlandsā€“A Nationwide Overview From 2008 Until 2022 (2025)Clinical oncology, 38. Article 103740. Evers, J., van der Sangen, M. J. C., van Maaren, M. C., Maduro, J. H., Strobbe, L., Aarts, M. J., Bloemers, M. C. W. M., Wesseling, J., van den Bongard, D. H. J. G., Struikmans, H. & Siesling, S.https://doi.org/10.1016/j.clon.2024.103740High-impact complications after breast cancer surgery in the Dutch national quality registry: evaluating case-mix adjustment for hospital comparisons (2025)BJS open, 9(1). Article zrae147. Verheul, E. M., Van Klaveren, D., Lingsma, H. F., Vos, E., Hoornweg, M. J., Siesling, S. & Koppert, L. B.https://doi.org/10.1093/bjsopen/zrae147Surgical treatment after neoadjuvant systemic therapy for HER2-positive invasive breast cancer in the Netherlands: 10-Year trends and the influence an accompanying DCIS component (2025)The Breast, 79. Article 103854. Ploumen, R. A. W., van Nijnatten, T. J. A., Kooreman, L. F. S., Voogd, A. C., Keymeulen, K. B. M. I., Siesling, S. & Smidt, M. L.https://doi.org/10.1016/j.breast.2024.103854ASO Author Reflections: Sentinel Lymph Node Biopsy for Patients with a Non-classic Lobular Carcinoma In Situ Breast Biopsy (2025)Annals of surgical oncology. Article 113500 (E-pub ahead of print/First online). Westenend, P. J., Meurs, C. J. C., Siesling, S. & Menke-Pluijmers, M. B. E.https://doi.org/10.1245/s10434-024-16863-9Working toward Personalized Intervention Advice: A Survey Study on Preference Heterogeneity in Patients with Breast Cancerā€“Related Fatigue (2025)MDM Policy and Practice, 10(1). Beenhakker, L., Wijlens, K. A. E., Bode, C., Vollenbroek-Hutten, M. M. R., Siesling, S., van Til, J. & Witteveen, A.https://doi.org/10.1177/23814683241309676The added value of physical examination for breast cancer recurrence detection in women: A systematic review (2025)Clinical breast cancer (E-pub ahead of print/First online). Godding, L. T. H., Klaassen-Dekker, A., Volders, J. H., van Hezewijk, M., Siemerink, E. J. M., van Uden, D., Veltman, J., Eijkelboom, A. & Siesling, S.https://doi.org/10.1016/j.clbc.2024.12.014Considerations to forgo systemic treatment in patients with advanced esophageal or gastric cancer: A realā€world evidence study (2025)International journal of cancer (E-pub ahead of print/First online). Slotman, E., Pape, M., van Laarhoven, H. W. M., Pouw, R. E., van der Linden, Y. M., Verhoeven, R. H. A., Siesling, S., Fransen, H. P. & Raijmakers, N. J. H.https://doi.org/10.1002/ijc.3531470-Gene signature-guided adjuvant systemic treatment adjustments in early-stage ER+ā€‰breast cancer patients: 7-year follow-up of a prospective multicenter cohort study (2025)Breast cancer research and treatment, 209, 331–340. Verreck, E. E. F., Kuijer, A., van Steenhoven, J. E. C., Volders, J. H., van der Velden, A. W. G., Siesling, S., Timmer-Bonte, A. N. H., Smilde, T. J., Imholz, A. L. T., Blanken-Peeters, C. F. J. M., de Valk, B., Vrijaldenhoven, S., Lastdrager, W. B., Haringhuizen, A. W., Hunting, J. C. B., Hovenga, S., Nieboer, P., Zuetenhorst, H. M., Tetteroo, G. W. M., ā€¦ van Dalen, T.https://doi.org/10.1007/s10549-024-07496-3

2024

Surgery for Classic, Pleomorphic and Non-classic Lobular Carcinoma In Situ: Surgery Rate, Risk of Upstaging and Short-Term Follow-Up (2024)Annals of surgical oncology (E-pub ahead of print/First online). Meurs, C. J. C., Kerkhoven, C., Siesling, S., Menke-Pluijmers, M. B. E. & Westenend, P. J.https://doi.org/10.1245/s10434-024-16686-8Adding Anti-HER2 Therapy to Neoadjuvant Endocrine Therapy Seems Effective in Hormone Receptor and HER2 Positive Breast Cancer Patients Unfit for Chemotherapy: A Nationwide Population-Based Cohort Study (2024)Cancers, 16(24). Article 4188. de Bruijn, A., Schipper, R.-J., Voogd, A. C., Pullens, M. J. J., Bloemen, J. G., de Munck, L., van Riet, Y. E., Siesling, S., Vriens, B. E. P. & Nieuwenhuijzen, G. A. P.https://doi.org/10.3390/cancers16244188Data-driven decision support for multidisciplinary clinical decision-making & reporting in breast cancer (2024)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Hendriks, M. P.https://doi.org/10.3990/1.9789036563390Long-term outcomes of young, node-negative, chemotherapy-naĆÆve, triple-negative breast cancer patients according to BRCA1 status (2024)BMC Medicine, 22. Article 9. Wang, Y., Dackus, G. M. H. E., Rosenberg, E. H., Cornelissen, S., de Boo, L. W., Broeks, A., Brugman, W., Chan, T. W. S., van Diest, P. J., Hauptmann, M., ter Hoeve, N. D., Isaeva, O. I., de Jong, V. M. T., Jóźwiak, K., Kluin, R. J. C., Kok, M., Koop, E., Nederlof, P. M., Opdam, M., ā€¦ Schmidt, M. K.https://doi.org/10.1186/s12916-023-03233-7Radiotherapy Trends and Variations in Invasive Non-metastatic Breast Cancer Treatment in the Netherlands: A Nationwide Overview From 2008 to 2019 (2024)Clinical oncology, 36(12), 765-779. Evers, J., van der Sangen, M. J. C., van Maaren, M. C., Maduro, J. H., Strobbe, L., Aarts, M. J., Bloemers, M. C. W. M., van den Bongard, D. H. J. G., Struikmans, H. & Siesling, S.https://doi.org/10.1016/j.clon.2024.08.010Shared decision-making supported by outcome information regarding surveillance after curative treatment for breast cancer: Results of the SHOUT-BC study (2024)European journal of cancer, 213. Article 115107. Ankersmid, J. W., Drossaert, C. H. C., Strobbe, L. J. A., Hackert, M. Q. N., Engels, N., Prick, J. C. M., Teerenstra, S., van Riet, Y. E. A., The, R., van Uden-Kraan, C. F. & Siesling, S.https://doi.org/10.1016/j.ejca.2024.115107Symptom Monitoring and Health-Related Quality of Life in Non-metastatic Breast Cancer Patients: A Systematic Review (2024)Current Breast Cancer Reports, 16(4), 417-428. Vrancken Peeters, N. J. M. C., Koppert, L. B., Jager, A., Hendriks, M. P., Siesling, S. & van den Hurk, C. J. G.https://doi.org/10.1007/s12609-024-00562-1Clinical and patient-reported outcomes after oncoplastic versus conventional breast conserving surgery: A longitudinal, multicenter cohort study (2024)Journal of the National Cancer Institute (E-pub ahead of print/First online). Bargon, C. A., Mink van der Molen, D. R., Young-Afat, D. A., Batenburg, M. C. T., van Dam, I. E., Baas, I. O., Ernst, M. F., Maarse, W., Sier, M. F., Schoenmaeckers, E., Burgmans, J. P. J., Bijlsma, R., Siesling, S., Rakhorst, H. A., Mureau, M. A. M., van der Leij, F., Doeksen, A. & Verkooijen, H. M.https://doi.org/10.1093/jnci/djae310Guidelines versus real-world data in metastatic bladder cancer: A population-based study on first-line chemotherapy treatment patterns (2024)Urologic Oncology (E-pub ahead of print/First online). Slotman, E., Richters, A., Fransen, H. P., Smilde, T. J., van der Linden, Y. M., Siesling, S., Aben, K. K. H. & Raijmakers, N. J. H.https://doi.org/10.1016/j.urolonc.2024.10.026

Research profiles

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