dr.ir. T. Heida (Ciska)

Ciska Heida (PhD) is an Associate Professor in the Biomedical Signals & Systems group. She has a background in Electrical Engineering with a specialization in Biomedical Engineering (MSc 1997) and received her PhD in the field of neurotechnology at the University of Twente in 2002. Her current research interests focus on increasing our understanding of the central mechanisms of human motor control, the pathophysiology underlying movement disorders, and the application of neuromodulation techniques for restoring motor control. Her teaching activities are related to signal analysis of biomedical/clinical data and bioelectromagnetics.

Medicine & Life Sciences

# Basal Ganglia
# Cues
# Deep Brain Stimulation
# Essential Tremor
# Motor Cortex
# Parkinson Disease
# Subthalamic Nucleus
# Tremor

Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS), Biomedical Signals and Systems (BSS)

How does human neural circuitry control posture and voluntary movements? Insight into the central mechanisms of human motor control and motor disorders such as Parkinson’s disease forms the basis for development of advanced therapies. Deep Brain Stimulation (DBS) and cueing can be used to improve symptoms for Parkinson’s disease patients (e.g. tremor, bradykinesia, rigidity). However, the mechanisms of DBS and cueing are still unclear and especially with DBS side-effects may occur. It is not well known which neuronal elements and pathways are activated or blocked with these treatments, and how the entire neural circuitry responds to the induced activation patterns since there is still limited knowledge of the connections within this network.

With the use of computational models of (part of) the brain networks involved in motor control we study the function of these networks and the effects of neuromodulation on network behaviour. In addition, experimental research including movement tests performed by patients while recording brain activity (LFP, MER, EEG, fNIRS) provide us with information regarding the (patho)physiology, the mechanisms and clinical effects of neuromodulation techniques. Based on these insights we develop new techniques and methods for diagnostic and therapeutic purposes.

Sharifi, S., Buijink, A. W. G. , Luft, F., Scheijbeler, E. P., Potters, W. V., van Wingen, G. , Heida, T. , Bour, L. J., & van Rootselaar, A. F. (2022). Differences in Olivo-Cerebellar Circuit and Cerebellar Network Connectivity in Essential Tremor: a Resting State fMRI Study. Cerebellum. https://doi.org/10.1007/s12311-022-01486-1

Smid, A., Elting, J. W. J., Dijk, J. M. C. V., Otten, B., Oterdoom, D. L. M., Tamasi, K. , Heida, T., Laar, T. V., & Drost, G. (2022). Intraoperative Quantification of MDS-UPDRS Tremor Measurements Using 3D Accelerometry: A Pilot Study. Journal of Clinical Medicine, 11, [2275]. https://doi.org/10.3390/jcm11092275

Sharifi, S. , Luft, F. , Boer, L. D., Buijink, A. W. G., Mugge, W. , Schouten, A. C. , Heida, T. , Bour, L. J., & Rootselaar, A. F. V. (2022). Closing the loop: Novel quantitative fMRI approach for manipulation of the sensorimotor loop in tremor. NeuroImage, 262, [119554]. https://doi.org/10.1016/j.neuroimage.2022.119554

Gilbert, A. M. M., Howell, B., Bower, K. L. , Veltink, P. H. , Heida, T., & McIntyre, C. C. (2021). Comparison of methodologies for modeling directional deep brain stimulation electrodes. PLoS ONE, 16(12), [e0260162]. https://doi.org/10.1371/journal.pone.0260162

Heijs, J. J. A., Havelaar, R. J., Fiedler, P. , van Wezel, R. J. A. , & Heida, T. (2021). Validation of soft multipin dry EEG electrodes. Sensors, 21(20), [6827]. https://doi.org/10.3390/s21206827

Janssen, S., Heijs, J. J. A. , Bittner, M. , Droog, E., Bloem, B. R. , van Wezel, R. J. A. , & Heida, T. (2021). Visual cues added to a virtual environment paradigm do not improve motor arrests in Parkinson's disease. Journal of neural engineering, 18(4), [046009]. https://doi.org/10.1088/1741-2552/abe356

van Dijk, K. J. (2021). Technological advances in deep brain stimulation: Towards an adaptive therapy. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036551885

Sharifi, S. , Luft, F., Potgieter, S. , Heida, T., Mugge, W. , Schouten, A. C. , Bour, L. J., & Rootselaar, A. F. V. (2021). Directionality of corticomuscular coupling in essential tremor and cortical myoclonic tremor. Clinical neurophysiology, 132(8), 1878-1886. https://doi.org/10.1016/j.clinph.2021.04.011

Janssen, S., de Ruyter van Steveninck, J., Salim, H. S., Bloem, B. R. , Heida, T. , & van Wezel, R. J. A. (2020). The Beneficial Effects of Conventional Visual Cues Are Retained When Augmented Reality Glasses Are Worn. Parkinson's Disease, 2020, [4104712]. https://doi.org/10.1155/2020/4104712

Janssen, S., de Ruyter van Steveninck, J., Salim, H. S., Cockx, H. M., Bloem, B. R. , Heida, T. , & van Wezel, R. J. A. (2020). The Effects of Augmented Reality Visual Cues on Turning in Place in Parkinson's Disease Patients With Freezing of Gait. Frontiers in neurology, 11, [185]. https://doi.org/10.3389/fneur.2020.00185

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Master

Courses in the current academic year are added at the moment they are finalised in the Osiris system. Therefore it is possible that the list is not yet complete for the whole academic year.

INTENSE - Innovative Neurotechnology for Society

https://www.utwente.nl/en/eemcs/bss/research-projects/intense-project/

PROMP - Personalised-care and Research on Motoric dysfunctioning for patient-specific treatments

https://www.utwente.nl/en/eemcs/bss/research-projects/PROMPT-project-description/

+31534892759

+31534892760 (if no answer)

t.heida@utwente.nl

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University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex (building no. 20), room ZH214
De Horst 2
7522LW Enschede
The Netherlands

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University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex ZH214
P.O. Box 217
7500 AE Enschede
The Netherlands

Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS), Biomedical Signals and Systems (BSS)

University of Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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