dr.ir. T. Heida (Ciska)

Associate Professor

About Me

Ciska Heida (PhD) is an Associate Professor in the Biomedical Signals & Systems group. She has a background in Electrical Engineering with a specialization in Biomedical Engineering (MSc 1997) and received her PhD in the field of neurotechnology at the University of Twente in 2002. Her current research interests focus on increasing our understanding of the central mechanisms of human motor control, the pathophysiology underlying movement disorders, and the application of neuromodulation techniques for restoring motor control. Her teaching activities are related to signal analysis of biomedical/clinical data and bioelectromagnetics.


Medicine & Life Sciences
Basal Ganglia
Deep Brain Stimulation
Essential Tremor
Motor Cortex
Parkinson Disease
Subthalamic Nucleus


How does human neural circuitry control posture and voluntary movements? Insight into the central mechanisms of human motor control and motor disorders such as Parkinson’s disease forms the basis for development of advanced therapies. Deep Brain Stimulation (DBS) and cueing can be used to improve symptoms for Parkinson’s disease patients (e.g. tremor, bradykinesia, rigidity). However, the mechanisms of DBS and cueing are still unclear and especially with DBS side-effects may occur. It is not well known which neuronal elements and pathways are activated or blocked with these treatments, and how the entire neural circuitry responds to the induced activation patterns since there is still limited knowledge of the connections within this network.

With the use of computational models of (part of) the brain networks involved in motor control we study the function of these networks and the effects of neuromodulation on network behaviour. In addition, experimental research including movement tests performed by patients while recording brain activity (LFP, MER, EEG, fNIRS) provide us with information regarding the (patho)physiology, the mechanisms and clinical effects of neuromodulation techniques. Based on these insights we develop new techniques and methods for diagnostic and therapeutic purposes.


Tran, S. , Heida, T. C., Heijs, J. J. A., Al-Ozzi, T., Sumarac, S., Alanazi, F. I., Kalia, S. K., Hodaie, M., Lozano, A. M., Milosevic, L., Chen, R., & Hutchison, W. D. (2024). Subthalamic and pallidal neurons are modulated during externally cued movements in Parkinson's disease. Neurobiology of disease, 190, Article 106384. https://doi.org/10.1016/j.nbd.2023.106384
Sharifi, S., Buijink, A. W. G. , Luft, F., Scheijbeler, E. P., Potters, W. V., van Wingen, G. , Heida, T. , Bour, L. J., & van Rootselaar, A. F. (2022). Differences in Olivo-Cerebellar Circuit and Cerebellar Network Connectivity in Essential Tremor: a Resting State fMRI Study. Cerebellum. https://doi.org/10.1007/s12311-022-01486-1
Smid, A., Elting, J. W. J., Dijk, J. M. C. V., Otten, B., Oterdoom, D. L. M., Tamasi, K. , Heida, T., Laar, T. V., & Drost, G. (2022). Intraoperative Quantification of MDS-UPDRS Tremor Measurements Using 3D Accelerometry: A Pilot Study. Journal of Clinical Medicine, 11, Article 2275. https://doi.org/10.3390/jcm11092275
Heijs, J. J. A., Havelaar, R. J., Fiedler, P. , van Wezel, R. J. A. , & Heida, T. (2021). Validation of soft multipin dry EEG electrodes. Sensors, 21(20), Article 6827. https://doi.org/10.3390/s21206827
van Dijk, K. J. (2021). Technological advances in deep brain stimulation: Towards an adaptive therapy. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036551885

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INTENSE - Innovative Neurotechnology for Society 


PROMP - Personalised-care and Research on Motoric dysfunctioning for patient-specific treatments




Contact Details

Visiting Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex (building no. 20), room ZH214
De Horst 2
7522LW  Enschede
The Netherlands

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Mailing Address

University of Twente
Faculty of Electrical Engineering, Mathematics and Computer Science
Horst Complex  ZH214
P.O. Box 217
7500 AE Enschede
The Netherlands

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