dr.ir. W.K. den Otter (Wouter)

2016 - now: Assistant professor (associate professor since 2018) at the Faculty of Engineering Technology at the University of Twente.

2011 - 2016: Assistant professor at the Faculty of Science and Technology and the Faculty of Constructive Sciences of the Universiteit Twente, using simulations and statistical mechanical theory to explore the assembly of clathrin-coated pits against a cell membrane, developing polymorph patchy particles to explore the aggregation processes of alpha-synuclein in Parkinson's disease, and derived & validated a quaternion-based rotational Brownian Dynamics algorithm.

2003 - 2011: Assistant professor a the Faculty of Science and Technology of the Universiteit Twente, using (highly) coarse-grained models in combinations with Molecular Dynamics, Brownian Dynamics and free-energy techniques to study the mechanical and dynamical properties of lipid membranes, the thermodynamics of trans-membrane pores, the periodic tumbling of liquid crystals under shear, the dynamics of liquid-liquid interfaces, the dynamical properties of (sheared) polymeric solutions and of polymer melts, viscous effects in Atomic Force Microscopy, (de-)mixing of granules in a rotating drum, and the self-assembly to three-legged clathrin proteins into polyhedral cages.

2001 - 2003: PostDoc at the Faculty of Physics of the Universiteit Twente, exploring the mechanical properties of lipid bilayers and worm-like micelles by coarse-grained simulations.

1998 - 2001: PostDoc at the chemistry department of the University of Manchester Institute of Science and Technology (UMIST, Manchester, UK), simulating liquid crystals with Dissipative Particle Dynamics and free energies with Molecular Dynamics.

1993 - 1998: PhD student at the faculty of chemical engineering of the Universiteit Twente (UT, Enschede, The Netherlands), combining statistical mechanics of rare events with Molecular Dynamics simulations to study the free-energy landscape and conformational transition rates of calix[4]arenes in solutions.

1987 - 1993: Student of applied physics (ingenieur, MSc) at the Technische Universiteit Eindhoven (TUE, Eindhoven, The Netherlands), with an emphasis on solid state physics, graduating in simulations of Low Energy Ion Scattering (LEIS) of a supported rhodium catalyst.

Chemistry

# Colloid
# Molecular Dynamics
# Simulation

Physics & Astronomy

# Colloids
# Liquids
# Molecular Dynamics
# Shear Thinning
# Simulation

Faculty of Engineering Technology (ET), Multi Scale Mechanics (MSM)

Sitlapersad, R. S. (2023). Molecular simulations of Supercapacitors. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036558129

Hulikal Chakrapani, T. , Bazyar, H. , Lammertink, R. G. H. , Luding, S. , & den Otter, W. K. (2023). The permeability of pillar arrays in microfluidic devices: an application of Brinkman's theory towards wall friction. Soft matter, 19(3), 436-450. https://doi.org/10.1039/d2sm01261h

Hulikal Chakrapani, T. (2022). Mesoscale Modelling of Multiphase Flow and Wetting. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036554756

Kuninty, P. R. , Binnemars-Postma, K. , Jarray, A., Pednekar, K. P. , Heinrich, M. A., Pijffers, H. J. , ten Hoopen, H. , Storm, G., van Hoogevest, P. , den Otter, W. K. , & Prakash, J. (2022). Cancer immune therapy using engineered ‛tail-flipping’ nanoliposomes targeting alternatively activated macrophages. Nature communications, 13(1), [4548]. https://doi.org/10.1038/s41467-022-32091-9

Cats, P., Sitlapersad, R. S. , den Otter, W. K. , Thornton, A. R., & van Roij, R. (2022). Capacitance and Structure of Electric Double Layers: Comparing Brownian Dynamics and Classical Density Functional Theory. Journal of Solution Chemistry, 51, 296-319. https://doi.org/10.1007/s10953-021-01090-7

Sitlapersad, R. S. , den Otter, W. K. , & Thornton, A. R. (2021). Capacitance and Structure of Electric Double Layers. Poster session presented at Physics@Veldhoven 2021, Online Event, Netherlands.

Sitlapersad, R. S. , den Otter, W. K. , & Thornton, A. R. (2021). Constant Potential by the Particle-Particle-Particle-Mesh Method. Poster session presented at 6th International Conference on Ionic Liquid-Based Materials, ILMAT 2021, Alsace, France.

Roy, S. , Luding, S. , Den Otter, W. K. , Thornton, A. R. , & Weinhart, T. (2021). Drift-diffusive liquid migration in partly saturated sheared granular media. Journal of fluid mechanics, 915, [A30]. https://doi.org/10.1017/jfm.2021.30

Hulikal Chakrapani, T. , & den Otter, W. K. (2020). Capillary Imbibition of Binary Fluid Mixtures in Nanochannels. Langmuir, 36(42), 12712-12722. https://doi.org/10.1021/acs.langmuir.0c02361

Palanisamy, D. , & den Otter, W. K. (2020). Fluctuating Brownian stresslets and the intrinsic viscosity of colloidal suspensions. The Journal of chemical physics, 152, [074901]. https://doi.org/10.1063/1.5141527

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