I am interested in how macroscopic behaviour of soft matter systems relates to their microscopic composition. If we know the properties of the microscopic particles, can we predict the behaviour of a macroscopic system containing many millions of these particles? Current and past applications range from ionic liquids in supercapacitors, liquid in porous media and self-assembly of protein cages to lipid membranes, liquid crystals and polymer melts. Based on concepts from statistical mechanics, it is possible to determine the static and dynamic properties of these systems by particle-based simulation techniques like molecular dynamics and Brownian dynamics.

Expertise

  • Physics

    • Simulation
    • Particle
    • Liquids
    • Model
    • Colloid
    • Molecular Dynamics
  • Chemistry

    • Polymer
    • Procedure

Organisations

Publications

2024

Pressure Anisotropy in Polymer Brushes and Its Effects on Wetting (2024)Langmuir, 40(8), 4401-4409. Veldscholte, L. B., Snoeijer, J. H., den Otter, W. K. & de Beer, S.https://doi.org/10.1021/acs.langmuir.3c03727Charging and discharging a supercapacitor in molecular simulations (2024)The Journal of chemical physics, 160(4). Article 044111. Sitlapersad, R. S., Thornton, A. R. & den Otter, W. K.https://doi.org/10.1063/5.0177103A simple efficient algorithm for molecular simulations of constant potential electrodes (2024)The Journal of chemical physics, 160(3). Article 034107. Sitlapersad, R. S., Thornton, A. R. & den Otter, W. K.https://doi.org/10.1063/5.0171502

2023

Molecular simulations of Supercapacitors (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Sitlapersad, R. S.https://doi.org/10.3990/1.9789036558129Numerical simulations of liquid bridges between colloids (2023)[Contribution to conference › Poster] Burgers Symposium 2023. Onofri, S., Hulikal Chakrapani, T., Luding, S., Scholten, E., Jarray, A. & den Otter, W. K.Numerical simulations of liquid bridges between colloids (2023)[Contribution to conference › Poster] NWO Physics 2023. Onofri, S., Hulikal Chakrapani, T., Luding, S., Scholten, E., Jarray, A. & den Otter, W. K.Stress-dependent macromolecular crowding in the mitochondrial matrix (2023)EMBO journal, 42(7). Article e108533. Bulthuis, E. P., Dieteren, C. E. J., Bergmans, J., Berkhout, J., Wagenaars, J. A., van de Westerlo, E. M. A., Podhumljak, E., Hink, M. A., Hesp, L. F. B., Rosa, H. S., Malik, A. N., Lindert, M. K. t., Willems, P. H. G. M., Gardeniers, H. J. G. E., den Otter, W. K., Adjobo-Hermans, M. J. W. & Koopman, W. J. H.https://doi.org/10.15252/embj.2021108533The permeability of pillar arrays in microfluidic devices: an application of Brinkman's theory towards wall friction (2023)Soft matter, 19(3), 436-450. Hulikal Chakrapani, T., Bazyar, H., Lammertink, R. G. H., Luding, S. & den Otter, W. K.https://doi.org/10.1039/d2sm01261h

2022

Cancer immune therapy using engineered ‛tail-flipping’ nanoliposomes targeting alternatively activated macrophages (2022)Nature communications, 13(1). Article 4548. Kuninty, P. R., Binnemars-Postma, K., Jarray, A., Pednekar, K. P., Heinrich, M. A., Pijffers, H. J., ten Hoopen, H., Storm, G., van Hoogevest, P., den Otter, W. K. & Prakash, J.https://doi.org/10.1038/s41467-022-32091-9Mesoscale Modelling of Multiphase Flow and Wetting (2022)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Hulikal Chakrapani, T.https://doi.org/10.3990/1.9789036554756

Research profiles

Address

University of Twente

Horst Complex (building no. 20), room N230
De Horst 2
7522 LW Enschede
Netherlands

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