dr. X.G.L.V. Pouwels (Xavier)

Assistant Professor

About Me

Before joining the department of Health Technology and Services research in 2020, Xavier performed his doctoral research, "Embracing Uncertainty in Health Technology Assessment", at the Maastricht University Medical Centre+. His research interests are the use of simulation models to evaluate the value of new health care technologies and how to improve the transparency of these simulation models. Currently, Xavier is involved in research projects focusing on the early detection of (risk factors for) cardiovascular diseases. Xavier also teaches the basic principles of (early) health economic evaluations in multiple study programs (Bachelor Health Sciences and Master Biomedical Engineering).


Medicine & Life Sciences
Cost-Benefit Analysis
Delivery Of Health Care
Quality-Adjusted Life Years
Social Sciences


Egmond, S. V., van Vliet, E. D., Wakkee, M., Hollestein, L. M. , Pouwels, X. G. L. V. , Koffijberg, H., Misirli, Y., Bakkum, R. S. L. A., Bastiaens, M. T., Kukutsch, N. A., Oosting, A. J., Plasmeijer, E. I., van Rengen, A., de Roos, K. P., Nijsten, T. E. C., de Vries, E., & de Bekker-Grob, E. W. (2022). Efficacy, cost-minimization, and budget impact of a personalized discharge letter for basal cell carcinoma patients to reduce low-value follow-up care. PLoS ONE, 17, [e0260978]. https://doi.org/10.1371/journal.pone.0260978
Grimm, S. E. , Pouwels, X., Ramaekers, BLT., van, R. NT., Sankatsing, VDV., Grutters, J. P. C., & Joore, MA. (2021). Implementation Barriers to Value of Information Analysis in Health Technology Decision Making: Results From a Process Evaluation. Value in health, 24(8), 1126-1136. https://doi.org/10.1016/j.jval.2021.03.013
Grimm, SE. , Pouwels, X., Ramaekers, BLT., Wijnen, B., Otten, T., Grutters, J. P. C., & Joore, MA. (2021). State of the ART? Two New Tools for Risk Communication in Health Technology Assessments. PharmacoEconomics, 39(10), 1185-1196. https://doi.org/10.1007/s40273-021-01060-3
Schneider, PP., Ramaekers, B. , Pouwels, X., Geurts, S., Ibragimova, K., den, B. M., Vriens, B., van, D. W. Y., den, B. M., Pepels, M., Tjan-Heijnen, V., & Joore, M. (2021). Direct Medical Costs of Advanced Breast Cancer Treatment: A Real-World Study in the Southeast of The Netherlands. Value in health, 24(5), 668-675. https://doi.org/10.1016/j.jval.2020.12.007
Wang, J. , Pouwels, X. G. L. V., Ramaekers, B. L. T., Frederix, G. W., van Lieshout, C., Hogenveen, R., Li, X., de Wit, G. A., Joore, M. A. , Koffijberg, H., van Giessen, A., & Feenstra, T. (2021). Multi-use disease models : A blueprint for application in support of health care insurance coverage policy and a case study in Diabetes Mellitus. RIVM. https://doi.org/10.21945/RIVM-2020-0145
Witlox, W. J. A., Grimm, S. E. , Riemsma, R., Armstrong, N., Ryder, S., Duffy, S., Carrera, V. H., Posadzki, P., Worthy, G. , Pouwels, X. G. L. V., Ramaekers, B. L. T., Kleijnen, J., Joore, M. A., & van Asselt, A. D. I. (2021). Lenalidomide with Rituximab for Previously Treated Follicular Lymphoma and Marginal Zone Lymphoma: An Evidence Review Group Perspective of a NICE Single Technology Appraisal. PharmacoEconomics, 39(2), 171-180. https://doi.org/10.1007/s40273-020-00971-x
Petersohn, S. , Pouwels, X., Ramaekers, B., ten Cate-Hoek, A., & Joore, M. (2020). Rivaroxaban plus aspirin for the prevention of ischaemic events in patients with cardiovascular disease: a cost-effectiveness study. European journal of preventive cardiology, 27(13), 1354-1365. https://doi.org/10.1177/2047487320913380

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University of Twente
Faculty of Behavioural, Management and Social Sciences
Technohal (building no. 18), room 3306
Hallenweg 5
7522NH  Enschede
The Netherlands

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University of Twente
Faculty of Behavioural, Management and Social Sciences
Technohal  3306
P.O. Box 217
7500 AE Enschede
The Netherlands