Before joining the department of Health Technology and Services research in 2020, Xavier performed his doctoral research, "Embracing Uncertainty in Health Technology Assessment", at the Maastricht University Medical Centre+. His research interests are the use of simulation models to evaluate the value of new health care technologies and how to improve the transparency of these simulation models. Currently, Xavier is involved in research projects focusing on the early detection of (risk factors for) cardiovascular diseases. Xavier also teaches the basic principles of (early) health economic evaluations in multiple study programs (Bachelor Health Sciences and Master Biomedical Engineering).

Expertise

  • Medicine and Dentistry

    • Cost-Effectiveness Analysis
    • Health Care Cost
    • Patient
    • Quality Adjusted Life Year
    • Therapeutic Procedure
    • Cardiovascular Disease
    • Systematic Review
    • Breast Cancer

Organisations

Publications

2025

Who Needs Real Data Anyway? Exploring the Use of Synthetic Data in Economic Evaluations of Health Interventions (2025)Value in health, 28(11), 1722-1731. van der Linden, N., Pouwels, X. G. L. V., Jahn, B., Siebert, U. & Koffijberg, H.https://doi.org/10.1016/j.jval.2025.06.007Cost-effectiveness analysis of the covered endovascular reconstruction of the aortic bifurcation versus kissing stents and open surgical repair for the treatment of aorto-iliac occlusive disease (2025)The European journal of health economics (E-pub ahead of print/First online). Pouwels, X. G. L. V., Holewijn, S., Veen, D. v. d., Gonzalez-Urquijo, M., Reijnen, M. M. P. J. & Koffijberg, H.https://doi.org/10.1007/s10198-025-01792-5Mapping the Landscape of Open Source Health Economic Models: A Systematic Database Review and Analysis: An ISPOR Special Interest Group Report (2025)Value in health, 28(6), 813-820. Henderson, R. H., Sampson, C., Pouwels, X. G. L. V., Harvard, S., Handels, R., Feenstra, T., Bhandari, R., Sepassi, A. & Arnold, R.https://doi.org/10.1016/j.jval.2025.01.019Cost-Effectiveness of Three Different New-Generation Drug-Eluting Stents in the Randomised BIO-RESORT Trial at 3 Years (2025)PharmacoEconomics - Open, 9(1), 137–145. Article e000064. Ploumen, E. H., Oude Wolcherink, M. J., Buiten, R. A., Pinxterhuis, T. H., Doggen, C. J. M., Schotborgh, C. E., Danse, P. W., Scholte, M., van Houwelingen, K. G., Zocca, P., Pouwels, X. G. L. V. & von Birgelen, C.https://doi.org/10.1007/s41669-024-00539-x

2024

Cost-effectiveness analysis of transthoracic echocardiographic assessment in patients with ischemic stroke or TIA of undetermined cause (2024)Journal of Stroke & Cerebrovascular Diseases, 33(12). Article 108013. van der Maten, G., Pouwels, X. G. L. V., Meijs, M. F. L., von Birgelen, C., den Hertog, H. M. & Koffijberg, H.https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108013Validating Health Economic Models With the Probabilistic Analysis Check dashBOARD (2024)Value in health, 27(8), 1073-1084. Pouwels, X. G. L. V., Kroeze, K., van der Linden, N., Kip, M. M. A. & Koffijberg, H.https://doi.org/10.1016/j.jval.2024.04.008A Blueprint for Multi-use Disease Modeling in Health Economics: Results from Two Expert-Panel Consultations (2024)PharmacoEconomics, 42(7), 797-810. Wang, J., Pouwels, X., Ramaekers, B., Frederix, G., van Lieshout, C., Hoogenveen, R., Li, X., de Wit, G. A., Joore, M., Koffijberg, H., van Giessen, A., Knies, S. & Feenstra, T.https://doi.org/10.1007/s40273-024-01376-wSource code of the Probabilistic Analysis Check dashBOARD (PACBOARD) (2024)[Dataset Types › Dataset]. Zenodo. Pouwels, X. & Kroeze, K. A.https://doi.org/10.5281/zenodo.11279943Introducing Open Science in Teaching Health Economic Modelling (2024)PharmacoEconomics - Open, 8, 347-357. Pouwels, X. G. L. V. & Koffijberg, H.https://doi.org/10.1007/s41669-023-00469-0Cost-effectiveness of home-based screening of the general population for albuminuria to prevent progression of cardiovascular and kidney disease (2024)EClinicalMedicine, 68. Article 102414. Pouwels, X. G. L. V., Mil, D. v., Kieneker, L. M., Boersma, C., Etten, R. W. v., Evers-Roeten, B., Heerspink, H. J. L., Hemmelder, M. H., Langelaan, M., Thelen, M., Gansevoort, R. T. & Koffijberg, H.https://doi.org/10.1016/j.eclinm.2023.102414

Research profiles

Address

University of Twente

Technohal (building no. 18), room 3306
Hallenweg 5
7522 NH Enschede
Netherlands

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